Entresto 市场按适应症、剂型、强度、年龄层、性别、分销管道、最终用户和地区划分

2025 年创业市场规模估计为 90.9 亿美元，预计到 2032 年将达到 122.1 亿美元，2025 年至 2032 年的复合年增长率为 4.3%。

心臟衰竭盛行率不断上升以及对创新治疗方案日益增长的需求的推动，全球恩欣妥 (Entresto) 市场在心血管治疗领域占据关键地位。恩欣妥是一种突破性的血管收缩素受体-脑啡肽酶抑制剂 (ARNI)，它透过将沙库巴曲和Valsartan结合在单一製剂中，心臟衰竭治疗带来了革命性的变化，与传统的血管紧张素转换酶 (ACE) 抑制剂相比，其临床疗效更为卓越。

这种双机制药物透过阻断血管收缩素II 受体并同时抑制脑啡肽酶（一种降解有益利钠肽的酶）来增强心血管保护并改善患者预后。人口老化、久坐不动的生活方式以及糖尿病和高血压等併发症的日益增加（这些併发症会导致心臟衰竭）显着推动了市场扩张。 Entresto 的临床和经济价值已得到全球医疗保健系统的认可，这从其被纳入主要心臟衰竭治疗指南以及在已开发市场和新兴市场日益普及可以看出。

市场动态

全球 Entresto 市场受到多个强劲驱动因素的支撑，这些因素凸显了其强劲的成长轨迹和市场渗透潜力。第一个驱动因素是全球心臟衰竭负担日益加重，影响全球超过 6,400 万人。人口老化和生活方式相关的心血管危险因子不断扩大，需要先进治疗性介入的患者群体也随之扩大。临床证据表明，与传统疗法相比，Entresto 在降低心血管死亡率和心臟衰竭住院率方面具有更显着的疗效，这正在加速医生对 Entresto 的采用，并促使各大循环系统协会将其纳入指南推荐。

医疗保健的经济压力和基于价值的护理计划正在进一步推动市场成长，因为 Entresto 已透过降低住院率和改善生活品质证明了其成本效益。然而，市场扩张面临重大限制因素，包括与学名药相比价格较高，这给价格敏感型市场的可及性带来了挑战，并限制了其在预算受限的医疗保健系统中的采用。此外，某些禁忌症，如有血管性水肿病史的患者和更容易受到副作用影响的某些族裔患者，限制了目标患者群体。复杂的滴定要求和潜在的药物交互作用也对医疗保健提供者的处方构成挑战。儘管有这些限制，但新兴市场地域分布的不断扩大、探索新适应症（包括射血分数保留的心臟衰竭）的临床试验正在进行中，以及可以显着扩展治疗用途和市场范围的联合治疗的潜力，正在涌现出巨大的商机。

本报告的主要特点

• 本报告对全球创业市场进行了详细分析，并以 2024 年为基准年，展示了预测期（2025-2032 年）的市场规模和复合年增长率。
• 它还强调了每个领域的潜在商机，并描述了该市场的一系列有吸引力的投资提案。
• 它还提供了有关市场驱动因素、限制因素和机会、新产品发布和核准、市场趋势、区域前景和主要企业采用的竞争策略的重要见解。
• 全球 Entresto 市场的主要企业已根据以下参数进行分析，例如公司概况、产品系列、主要亮点、财务表现和策略。
• 主要公司包括诺华公司。
• 本报告的见解将使负责人和企业经营团队能够就未来的产品发布、合作伙伴关係、市场扩张和行销策略做出明智的决策。
• 「全球 Entresto 市场」报告涉及该行业的各个相关人员，包括投资者、供应商、产品製造商、经销商、新进业者和金融分析师。
• 相关人员可以透过用于分析全球 Entresto 市场的各种策略矩阵更轻鬆地做出决策。

目录

第一章 分析目标与前提条件

• 分析目的
• 先决条件
• 简称

第二章 市场展望

• 报告描述
  • 市场定义和范围
• 执行摘要

第三章：市场动态、法规与趋势分析

• 市场动态
• 驱动程式
• 抑制因素
• 机会
• 影响分析
• 主要进展
• 监管情景
• 产品发布/核准
• PEST分析
• 波特五力分析
• 企业合併（M&A）场景
• 产业趋势

4. 全球 Entresto 市场以适应症划分（以金额为准，2020-2032 年）

• 慢性心臟衰竭（CHF）
• 儿科患者左心室收缩功能障碍伴随症状性心臟衰竭衰竭

5. 全球 Entresto 市场按剂型划分（以金额为准，2020-2032 年）

• 膜衣锭
• 胶囊中的薄膜衣口服颗粒

6. 全球 Entresto 市场以强度划分（以金额为准，2020-2032 年）

• 24/26mg
• 49/51mg
• 97/103 mg
• 6mg/6mg
• 15mg/16mg

7. 全球 Entresto 市场按年龄组别划分（以金额为准，2020-2032 年）

• 成人
• 孩子们

8. 全球 Entresto 市场以性别划分（以金额为准，2020-2032 年）

• 男性
• 女士

9. 全球 Entresto 市场按分销管道划分（以金额为准，2020-2032 年）

• 医院药房
• 零售药局
• 网路药局

第 10 章：全球 Entresto 市场以最终用户划分（以金额为准，2020-2032 年）

• 医院和诊所
• 心臟病中心
• 长期照护机构
• 门诊治疗中心
• 居家医疗
• 其他（学术研究机构等）

第 11 章 按地区分類的全球 Entresto 市场（以金额为准，2020-2032 年）

• 北美洲
  • 美国
  • 加拿大
• 拉丁美洲
  • 巴西
  • 阿根廷
  • 墨西哥
  • 其他拉丁美洲
• 欧洲
  • 德国
  • 英国
  • 西班牙
  • 法国
  • 义大利
  • 俄罗斯
  • 其他欧洲国家
• 亚太地区
  • 中国
  • 印度
  • 日本
  • 澳洲
  • 韩国
  • ASEAN
  • 其他亚太地区
• 中东
  • 海湾合作委员会国家
  • 以色列
  • 其他中东地区
• 非洲
  • 南非
  • 北非
  • 中部非洲

第十二章竞争格局

• Novartis AG

第十三章 分析师建议

• “命运之轮”
• 分析师观点
• Coherent Opportunity Map (COM)

第十四章参考文献与调查方法

• 参考
• 分析方法
• 关于 Coherent Market Insights

ENTRESTO Market is estimated to be valued at USD 9.09 Bn in 2025 and is expected to reach USD 12.21 Bn by 2032, growing at a compound annual growth rate (CAGR) of 4.3% from 2025 to 2032.

The Global ENTRESTO Market represents a pivotal segment within the cardiovascular therapeutics landscape, driven by the increasing prevalence of heart failure and the growing demand for innovative treatment solutions. ENTRESTO, a groundbreaking angiotensin receptor-neprilysin inhibitor (ARNI), has revolutionized heart failure management by combining sacubitril and valsartan in a single formulation, offering superior clinical outcomes compared to traditional ACE inhibitors.

This dual-mechanism medication works by simultaneously blocking the angiotensin II receptor and inhibiting neprilysin, an enzyme responsible for breaking down beneficial natriuretic peptides, thereby providing enhanced cardiovascular protection and improved patient outcomes. The market's expansion is significantly influenced by the rising geriatric population, sedentary lifestyles, and increasing incidence of comorbidities such as diabetes and hypertension that contribute to heart failure development. Healthcare systems worldwide are increasingly recognizing the clinical and economic value of ENTRESTO, as evidenced by its inclusion in major heart failure treatment guidelines and growing adoption across both developed and emerging markets.

Market Dynamics

The Global ENTRESTO Market is propelled by several compelling drivers that underscore its robust growth trajectory and market penetration potential. The primary driver stems from the escalating global burden of heart failure, affecting over 64 million people worldwide, coupled with aging demographics and lifestyle-related cardiovascular risk factors that continue to expand the patient population requiring advanced therapeutic interventions. Clinical evidence demonstrating ENTRESTO's superior efficacy in reducing cardiovascular mortality and heart failure hospitalizations compared to traditional treatments has accelerated physician adoption and guideline recommendations across major cardiology societies.

Healthcare economic pressures and value-based care initiatives further drive market growth as ENTRESTO demonstrates cost-effectiveness through reduced hospitalization rates and improved quality of life metrics. However, market expansion faces significant restraints including the medication's premium pricing compared to generic alternatives, which creates accessibility challenges in price-sensitive markets and limits adoption in healthcare systems with stringent budget constraints. Additionally, specific contraindications, including patients with a history of angioedema and certain ethnic populations with higher susceptibility to adverse reactions, restrict the eligible patient population. Complex titration requirements and potential drug interactions also pose prescribing challenges for healthcare providers. Despite these constraints, substantial opportunities emerge from expanding geographical presence in emerging markets, ongoing clinical trials investigating new indications including preserved ejection fraction heart failure, and potential combination therapies that could broaden therapeutic applications and market reach significantly.

Key Features of the Study

• This report provides an in-depth analysis of the global ENTRESTO market, and provides market size (USD Billion) and compound annual growth rate (CAGR%) for the forecast period (2025-2032), considering 2024 as the base year.
• It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market.
• This study also provides key insights about market drivers, restraints, opportunities, new product launches or approvals, market trends, regional outlook, and competitive strategies adopted by key players.
• It profiles key players in the global ENTRESTO market based on the following parameters - company highlights, products portfolio, key highlights, financial performance, and strategies.
• Key company covered as a part of this study include Novartis AG.
• Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics.
• The global ENTRESTO market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts.
• Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global ENTRESTO market.

Market Segmentation

• Indication Insights (Revenue, USD Bn, 2020 - 2032)
  • Chronic Heart Failure (CHF)
  • Symptomatic heart failure with left ventricular systolic dysfunction in pediatric patients
• Dosage Forms Insights (Revenue, USD Bn, 2020 - 2032)
  • Film-coated tablets
  • Film-coated oral pellets within capsules
• Strength Insights (Revenue, USD Bn, 2020 - 2032)
  • 24/26 mg
  • 49/51 mg
  • 97/103 mg
  • 6 mg/6 mg
  • 15 mg/16 mg
• Age Group Insights (Revenue, USD Bn, 2020 - 2032)
  • Adults
  • Pediatric
• Gender Insights (Revenue, USD Bn, 2020 - 2032)
  • Male
  • Female
• Distribution Channel Insights (Revenue, USD Bn, 2020 - 2032)
  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies
• End User Insights (Revenue, USD Bn, 2020 - 2032)
  • Hospitals and Clinics
  • Cardiology Centers
  • Long-Term Care Facilities
  • Ambulatory Care Centers
  • Homecare Settings
  • Others (Academic and Research Institutes, etc.)
• Regional Insights (Revenue, USD Bn, 2020 - 2032)
  • North America
  • U.S.
  • Canada
  • Latin America
  • Brazil
  • Argentina
  • Mexico
  • Rest of Latin America
  • Europe
  • Germany
  • U.K.
  • Spain
  • France
  • Italy
  • Russia
  • Rest of Europe
  • Asia Pacific
  • China
  • India
  • Japan
  • Australia
  • South Korea
  • ASEAN
  • Rest of Asia Pacific
  • Middle East
  • GCC Countries
  • Israel
  • Rest of Middle East
  • Africa
  • South Africa
  • North Africa
  • Central Africa
• Key Players Insights
  • Novartis AG

Table of Contents

1. Research Objectives and Assumptions

• Research Objectives
• Assumptions
• Abbreviations

2. Market Purview

• Report Description
  • Market Definition and Scope
• Executive Summary
  • Global ENTRESTO Market, By Indication
  • Global ENTRESTO Market, By Dosage Forms
  • Global ENTRESTO Market, By Strength
  • Global ENTRESTO Market, By Age Group
  • Global ENTRESTO Market, By Gender
  • Global ENTRESTO Market, By Distribution Channel
  • Global ENTRESTO Market, By End User
  • Global ENTRESTO Market, By Region

3. Market Dynamics, Regulations, and Trends Analysis

• Market Dynamics
• Driver
• Restraint
• Opportunity
• Impact Analysis
• Key Developments
• Regulatory Scenario
• Product Launches/Approvals
• PEST Analysis
• PORTER's Analysis
• Merger and Acquisition Scenario
• Industry Trends

4. Global ENTRESTO Market, By Indication, 2020-2032, (USD Bn)

• Introduction
  • Market Share Analysis, 2025 and 2032 (%)
  • Y-o-Y Growth Analysis, 2021 - 2032
  • Segment Trends
• Chronic Heart Failure (CHF)
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• Symptomatic heart failure with left ventricular systolic dysfunction in pediatric patients
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)

5. Global ENTRESTO Market, By Dosage Forms, 2020-2032, (USD Bn)

• Introduction
  • Market Share Analysis, 2025 and 2032 (%)
  • Y-o-Y Growth Analysis, 2021 - 2032
  • Segment Trends
• Film-coated tablets
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• Film-coated oral pellets within capsules
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)

6. Global ENTRESTO Market, By Strength, 2020-2032, (USD Bn)

• Introduction
  • Market Share Analysis, 2025 and 2032 (%)
  • Y-o-Y Growth Analysis, 2021 - 2032
  • Segment Trends
• 24/26 mg
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• 49/51 mg
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• 97/103 mg
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• 6 mg/6 mg
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• 15 mg/16 mg
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)

7. Global ENTRESTO Market, By Age Group, 2020-2032, (USD Bn)

• Introduction
  • Market Share Analysis, 2025 and 2032 (%)
  • Y-o-Y Growth Analysis, 2021 - 2032
  • Segment Trends
• Adults
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• Pediatric
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)

8. Global ENTRESTO Market, By Gender, 2020-2032, (USD Bn)

• Introduction
  • Market Share Analysis, 2025 and 2032 (%)
  • Y-o-Y Growth Analysis, 2021 - 2032
  • Segment Trends
• Male
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• Female
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)

9. Global ENTRESTO Market, By Distribution Channel, 2020-2032, (USD Bn)

• Introduction
  • Market Share Analysis, 2025 and 2032 (%)
  • Y-o-Y Growth Analysis, 2021 - 2032
  • Segment Trends
• Hospital Pharmacies
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• Retail Pharmacies
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• Online Pharmacies
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)

10. Global ENTRESTO Market, By End User, 2020-2032, (USD Bn)

• Introduction
  • Market Share Analysis, 2025 and 2032 (%)
  • Y-o-Y Growth Analysis, 2021 - 2032
  • Segment Trends
• Hospitals and Clinics
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• Cardiology Centers
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• Long-Term Care Facilities
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• Ambulatory Care Centers
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• Homecare Settings
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• Others (Academic and Research Institutes, etc.)
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)

11. Global ENTRESTO Market, By Region, 2020 - 2032, Value (USD Bn)

• Introduction
  • Market Share (%) Analysis, 2025, 2028 & 2032, Value (USD Bn)
  • Market Y-o-Y Growth Analysis (%), 2021 - 2032, Value (USD Bn)
  • Regional Trends
• North America
  • Introduction
  • Market Size and Forecast, By Indication, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Dosage Forms, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Strength, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Age Group, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Gender, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Distribution Channel, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By End User, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Country, 2020 - 2032, Value (USD Bn)
    • U.S.
    • Canada
• Latin America
  • Introduction
  • Market Size and Forecast, By Indication, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Dosage Forms, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Strength, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Age Group, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Gender, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Distribution Channel, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By End User, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Country, 2020 - 2032, Value (USD Bn)
    • Brazil
    • Argentina
    • Mexico
    • Rest of Latin America
• Europe
  • Introduction
  • Market Size and Forecast, By Indication, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Dosage Forms, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Strength, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Age Group, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Gender, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Distribution Channel, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By End User, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Country, 2020 - 2032, Value (USD Bn)
    • Germany
    • U.K.
    • Spain
    • France
    • Italy
    • Russia
    • Rest of Europe
• Asia Pacific
  • Introduction
  • Market Size and Forecast, By Indication, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Dosage Forms, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Strength, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Age Group, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Gender, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Distribution Channel, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By End User, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Country, 2020 - 2032, Value (USD Bn)
    • China
    • India
    • Japan
    • Australia
    • South Korea
    • ASEAN
    • Rest of Asia Pacific
• Middle East
  • Introduction
  • Market Size and Forecast, By Indication, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Dosage Forms, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Strength, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Age Group, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Gender, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Distribution Channel, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By End User, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Country, 2020 - 2032, Value (USD Bn)
    • GCC Countries
    • Israel
    • Rest of Middle East
• Africa
  • Introduction
  • Market Size and Forecast, By Indication, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Dosage Forms, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Strength, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Age Group, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Gender, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Distribution Channel, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By End User, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Country/Region, 2020 - 2032, Value (USD Bn)
    • South Africa
    • North Africa
    • Central Africa

12. Competitive Landscape

• Novartis AG
  • Company Highlights
  • Product Portfolio
  • Key Developments
  • Financial Performance
  • Strategies

13. Analyst Recommendations

• Wheel of Fortune
• Analyst View
• Coherent Opportunity Map

14. References and Research Methodology

• References
• Research Methodology
• About us