骨成长产品的全球市场 - Focused Insights(2024年～2029年)

2023年至2029年，全球骨生长产品市场规模预计将以3.72%的复合年增长率成长。

市场机会与推动因素

自供电植入式装置的兴起

侵入式骨骼生长刺激器是一种植入式设备，可将电能传送到未癒合的骨折或骨融合部位，以诱导骨形成、刺激生长并促进癒合。这些设备使用透过植入导线传递的直流电向骨折部位传递一致的电流，克服了非侵入性系统中发现的患者依从性问题。侵入式刺激器特别适用于胫骨、股骨和肱骨的非骨融合，并用于接受腰椎或骶骨融合的高风险患者（有融合失败史或有吸烟、肥胖或糖尿病等健康状况的患者）已被证明对患者有效。骨头是一种压电材料，因此应变会产生微小的电荷，有助于癒合。此类设备的优势越来越大，因此在已开发国家扩大采用，并且正在进行研究以提高其市场占有率和有效性。

骨形态发生蛋白（BMP）对脊椎融合和骨再生的影响

骨形态发生蛋白 (BMP) 是转化生长因子-β (TGF-β) 家族的一部分，已成为自体骨移植的有前途的替代品，特别是在脊椎融合手术和骨再生中。 BMP 于 2002 年获得 FDA 批准用于前路腰椎融合术，旨在促进骨癒合，并且比传统植入方法併发症更少。与髂嵴移植（ICBG）的76%相比，BMP显示出98%的高效率，并且适用于椎间融合、后外侧融合和环週融合等各种脊椎融合技术。 BMP 在安全性和有效性方面与 ICBG 相当，并且正在扩展到适应症外用途，例如后路脊椎融合和颈椎融合。 BMP 与 FGF、PDGF 和 IGF 等其他生物因子一起，在促进骨再生中发挥重要作用。儘管自体移植仍然是骨科手术的标准，但 BMP 提供了一个经过充分研究的有效替代方案。

扩大采用生物相容性合成骨移植物和生物製剂

越来越多地使用生物相容性合成骨移植物和生物製剂是骨生长产品市场的主要驱动力。由陶瓷、聚合物和复合材料等材料製成的合成骨移植物模仿天然骨结构，为新骨生长提供支架，同时消除与同种异体移植物和自体移植物相关的疾病，降低传播和免疫排斥的风险。这些植入物尤其适合脊椎融合手术和创伤病例。骨形态发生蛋白 (BMP) 和富血小板血浆 (PRP) 等生物製剂可透过促进细胞活性和骨生长来促进自然骨癒合。 BMP 诱导骨形成并改善复合骨折的结果，而 PRP 则促进癒合。这些创新正在改变骨损伤的治疗方法，提供更有效、高效和个人化的解决方案，并随着医疗保健提供者寻求更安全、更具成本效益的选择而扩大市场，我们正在促进成长。

产业限制因子

应对快速的技术进步

骨骼生长刺激剂价格昂贵，通常不在保险范围内，促使许多人寻求经济实惠的替代疗法，如物理治疗、阿育吠陀和脊椎按摩疗法。由于成本效益高，这些替代药物在日本、中国和印度等地区很受欢迎。此外，骨刺激器引起的不适以及骨科医生的缺乏迫使患者转向传统治疗。提高意识、改善治疗机会和扩大保险范围可能会支持中低收入地区采用骨生长产品。

竞争状况

市场竞争非常激烈，美敦力 (Medtronic)、强生 (Johnson & Johnson)、史赛克 (Stryker) 和 Zimmer Biomet 等跨国公司透过收购、合作和新产品推出处于领先地位。越来越多的中小企业进入市场，创新、高性价比的产品备受关注。为了应对骨再生的课题，特别是老年人和糖尿病患者的骨再生课题，人们越来越重视开发先进的骨癒合疗法，例如脉衝电磁场疗法。 Bioventus、Orthofix 和 Terumo 等领先公司正在透过创新解决方案增强其产品组合。

主要供应商

• Bioventus
• Enovis Corp
• Johnson & Johnson
• Medtronic
• Orthofix
• Stryker Corp
• Zimmer Biomet

其他的着名供应商

• Altis Biologics
• Bio-Dynamic Technologies
• BTT Health
• Cellumed
• Elizur
• EmCyte
• Fintek Bio-Electric
• IGEA
• ITO
• Kinex Medical
• Ossatec Benelux
• Pain Rehab Products
• Royal Biologics
• Fujifilm Corp
• Smith & Nephew
• Specialized Orthopedic Solutions
• Stimulate Health
• Terumo
• Globus Medical
• ATEC
• Moximed
• Anika Therapeutics
• Highridge Medical

本报告提供全球骨成长产品市场相关调查分析，各地区的收益与预测，预测与机会，竞争情形等资讯。

目录

第1章 骨成长产品市场概要

• 摘要整理
• 主要调查结果

第2章 骨成长产品市场

第3章 骨成长产品市场区隔资料

• 全球收益的预测:各产品
  • 骨生长刺激植入装置
  • 骨形成蛋白
  • 多血小板血浆
• 全球收益的预测:各用途
  • 脊椎融合手术
  • 口腔·颚颜面手术
  • 癒合延迟·不癒合骨折
  • 其他
• 全球收益的预测:各终端用户
  • 医院·诊疗所
  • 专门整形外科·脊椎中心
  • 门诊病人手术中心(ASC)

第4章 主要地区概要

• 北美的骨成长产品市场收益的预测
  • 美国的骨成长产品市场收益的预测
  • 加拿大的骨成长产品市场收益的预测
• 欧洲的骨成长产品市场收益的预测
  • 德国的骨成长产品市场收益的预测
  • 法国的骨成长产品市场收益的预测
  • 英国的骨成长产品市场收益的预测
  • 义大利的骨成长产品市场收益的预测
  • 西班牙的骨成长产品市场收益的预测
• 亚太地区的骨成长产品市场收益的预测
  • 中国的骨成长产品市场收益的预测
  • 日本的骨成长产品市场收益的预测
  • 印度的骨成长产品市场收益的预测
  • 澳洲的骨成长产品市场收益的预测
  • 韩国的骨成长产品市场收益的预测
• 南美的骨成长产品市场收益的预测
  • 巴西的骨成长产品市场收益的预测
  • 墨西哥的骨成长产品市场收益的预测
  • 阿根廷的骨成长产品市场收益的预测
• 中东·非洲的骨成长产品市场收益的预测
  • 土耳其的骨成长产品市场收益的预测
  • 沙乌地阿拉伯的骨成长产品市场收益的预测
  • 南非的骨成长产品市场收益的预测

第5章 骨成长产品市场预测和机会

• 骨成长产品市场机会和趋势
• 骨成长产品市场促进因素
• 骨成长产品市场阻碍因素

第6章 骨成长产品产业概要

• 骨成长产品市场 - 竞争情形
• 骨成长产品市场 - 主要供应商的简介
• 骨成长产品市场 - 其他的着名供应商
• 骨成长产品市场 - 主要策略的推荐事项

第7章 附录

The global bone growth products market is expected to grow at a CAGR of 3.72% from 2023 to 2029.

MARKET OPPORTUNITIES & DRIVERS

The Rise of Self-Powered Implantable Devices

Invasive bone growth stimulators are implantable devices that supply electrical energy to non-healing fractures or bone fusion sites, aiming to induce bone formation, stimulate growth, and promote healing. These devices, which use direct current delivered via an implanted lead, offer a consistent current to the fracture site, overcoming issues related to patient compliance seen in non-invasive systems. Invasive stimulators are particularly indicated for non-unions of the tibia, femur, and humerus and have proven effective for high-risk individuals undergoing lumbar or sacral fusion, including those with a history of fusion failure or conditions such as smoking, obesity, or diabetes. Bone, being a piezoelectric material, generates a small electrical charge under strain, which aids in healing. The growing advantages of these devices suggest increased adoption in developed countries, with ongoing research to enhance their market presence and efficacy.

Impact of Bone Morphogenetic Proteins (BMPs) in Spinal Fusion and Bone Regeneration

Bone morphogenetic proteins (BMPs), part of the transforming growth factor-beta (TGF-beta) family, have become a promising alternative to autologous bone grafts, especially in spinal fusion and bone regeneration. Approved by the FDA in 2002 for anterior lumbar fusion, BMPs aim to enhance bone healing with fewer complications than traditional grafting methods. They have shown high effectiveness, with fusion rates of 98% compared to 76% for iliac crest grafts (ICBGs), and are used in various spinal fusion techniques, including interbody, posterolateral, and circumferential fusion. BMPs are comparable to ICBGs in safety and efficacy and are expanding into off-label uses, such as posterior spinal fusion and cervical fusion. BMPs, alongside other biological factors like FGF, PDGF, and IGF, play a significant role in advancing bone regeneration. While autologous grafts remain the standard in orthopedic procedures, BMPs offer a well-researched, effective alternative.

The Rising Adoption of Biocompatible Synthetic Bone Grafts and Biologics

The growing use of biocompatible synthetic bone grafts and biologics is a key driver of the bone growth products market. Synthetic grafts, made from materials like ceramics, polymers, and composites, mimic natural bone structure, providing scaffolds for new bone growth while reducing disease transmission and immune rejection risks associated with allografts and autografts. These grafts are especially in demand for spinal fusion surgeries and trauma cases. Biologics, such as bone morphogenetic proteins (BMPs) and platelet-rich plasma (PRP), enhance natural bone healing by promoting cellular activity and bone growth. BMPs induce bone formation, improving outcomes in complex fractures, while PRP accelerates healing. These innovations are transforming the treatment of bone injuries, offering more effective, efficient, and personalized solutions, driving market growth as healthcare providers seek safer, cost-effective options.

INDUSTRY RESTRAINTS

Keeping Up with Rapid Technical Advancements

Bone growth stimulators are expensive and often not covered by insurance, leading many to seek affordable alternatives like physiotherapy, Ayurveda, and chiropractic care, especially in developing countries with high out-of-pocket costs. Due to their cost-effectiveness, these alternatives are popular in regions like Japan, China, and India. Additionally, discomfort from bone stimulators and a shortage of orthopedic surgeons drive patients toward traditional treatments. Expanding awareness, improving treatment access, and increasing insurance coverage could boost the adoption of bone growth products in low- and middle-income areas.

SEGMENTATION INSIGHTS

INSIGHTS BY PRODUCT

The global bone growth products market by product is segmented into bone growth stimulator devices, bone morphogenetic protein, and platelet-rich plasma. The bone growth stimulator devices segment accounted for the largest market share. Bone healing is a natural process, with the body continually replacing old bone with new. While fractures generally heal with appropriate treatments like casts, realignment, and surgery, complications such as delayed healing or non-union can occur. To address these issues, medical professionals seek ways to enhance and accelerate bone healing. Bone stimulators are designed to support this healing process and come in various forms, including electrical and ultrasonic stimulators. This segment dominates the market due to many patients preferring non-invasive or minimally invasive treatments to avoid surgical risks and long recovery periods. Bone growth stimulators, which can be used externally or with minimal intervention, align with this growing patient preference.

By Product

• Bone Growth Stimulator Devices
• Bone Morphogenetic Protein
• Platelet Rich Plasma

INSIGHTS BY APPLICATION

The global bone growth products market by application is categorized into spinal fusion surgeries, oral & maxillofacial surgeries, delayed union & non-union bone fractures, and others. The spinal fusion surgeries show the highest growth during the forecast period. Bone Growth Stimulation (BGS) is a therapeutic technique commonly prescribed by surgeons following spinal fusion procedures to enhance the healing of bones in the spine. A bone growth stimulator is often used for patients undergoing cervical (neck) or lumbar (low back) spine surgeries to promote spinal fusion. This device helps to improve bone healing by stimulating growth and is particularly beneficial in cases where the fusion process is delayed or fails. Studies have shown that BGS significantly enhances fusion outcomes in both cervical and lumbar regions, making it a popular choice for post-operative treatment, thus helping segmental growth.

By Application

• Spinal Fusion Surgeries
• Oral & Maxillofacial Surgeries
• Delayed Union & Non-union Bone Fractures
• Others

INSIGHTS BY END-USER

Based on the end-user, the hospitals & clinics segment holds the largest global bone growth products market share. Hospitals serve as the primary point of care for bone-related issues, often investing in advanced technologies and materials to improve treatment outcomes. However, only larger multispecialty and Tier-I hospitals provide cutting-edge treatments such as bone morphogenetic proteins (BMP) and platelet-rich plasma (PRP). This is due to the complexity and cost of these therapies. Increasing patient awareness and improved insurance coverage have fueled the demand for advanced treatments, including bone stimulators, BMP, and PRP, which are particularly effective for treating difficult fractures like non-union fractures. Physician offices and clinics, especially in remote areas, are many patients' first point of contact. While these facilities may not be able to offer advanced treatments, they play a crucial role in referring patients to larger, specialized hospitals, which are helping the market grow.

By End-User

• Hospitals & Clinics
• Specialty Orthopedic & Spine Centers
• Ambulatory Surgical Centers (ASCs)

GEOGRAPHICAL ANALYSIS

North America accounted for the largest global bone growth products market share, followed by Europe. The U.S. remains a major revenue contributor in North America due to the high penetration of spinal fusion procedures and a considerable volume of spinal fusion and non-fusion surgeries. The increasing prevalence of orthopedic diseases, accidental injuries, and the aging population primarily drive the growth. The availability of advanced, safer, and minimally invasive surgical treatments and ongoing technological innovations further support market expansion.

In Europe, Germany, France, the UK, Italy, and Spain are the primary revenue contributors to the global bone growth products market. This region benefits from a well-established and sophisticated healthcare infrastructure, providing access to advanced medical services, including spinal fusion and non-fusion procedures. The market's growth is driven by the increasing prevalence of bone disorders and the availability of reimbursement coverage for spinal fusion surgeries across many European countries.

By Geography

• North America
  • The U.S.
  • Canada
• Europe
  • Germany
  • France
  • UK
  • Italy
  • Spain
• APAC
  • China
  • Japan
  • India
  • Australia
  • South Korea
• Latin America
  • Brazil
  • Mexico
  • Argentina
• Middle East & Africa
  • Turkey
  • Saudi Arabia
  • South Africa

COMPETITIVE LANDSCAPE

The global bone growth products market report includes exclusive data on 30 vendors. The market is highly competitive, with global players like Medtronic, Johnson & Johnson, Stryker, and Zimmer Biomet leading through acquisitions, collaborations, and new product launches. Small and mid-sized companies increasingly enter the market, focusing on novel, cost-effective products. There is a growing emphasis on developing advanced bone healing therapies, such as pulsed electromagnetic field therapies, to address challenges in bone regeneration, especially for elderly and diabetic patients. Key players like Bioventus, Orthofix, and Terumo are enhancing their product portfolios with innovative solutions.

Key vendors

• Bioventus
• Enovis Corp
• Johnson & Johnson
• Medtronic
• Orthofix
• Stryker Corp
• Zimmer Biomet

Other Prominent Vendors

• Altis Biologics
• Bio-Dynamic Technologies
• BTT Health
• Cellumed
• Elizur
• EmCyte
• Fintek Bio-Electric
• IGEA
• ITO
• Kinex Medical
• Ossatec Benelux
• Pain Rehab Products
• Royal Biologics
• Fujifilm Corp
• Smith & Nephew
• Specialized Orthopedic Solutions
• Stimulate Health
• Terumo
• Globus Medical
• ATEC
• Moximed
• Anika Therapeutics
• Highridge Medical

KEY QUESTIONS ANSWERED:

1. How big is the global bone growth products market?

2. What Is the growth rate of the global bone growth products market?

3. Which region dominates the global bone growth products market?

4. Who are the major players in the global bone growth products market?

5. What are the key drivers of the global bone growth products market?

TABLE OF CONTENTS

CHAPTER - 1: Bone Growth Products Market Overview

• Executive Summary
• Key Findings

CHAPTER - 2: Bone Growth Products Market

• GLOBAL: Projected Revenue of Bone Growth Products Market (2020-2029; $Millions)

CHAPTER - 3: Bone Growth Products Market Segmentation Data

• GLOBAL: Projected Revenue by Product (2020-2029; $Millions)
  • Bone Growth Stimulator Devices
  • Bone Morphogenetic Protein
  • Platelet Rich Plasma
• GLOBAL: Projected Revenue by Application (2020-2029; $Millions)
  • Spinal Fusion Surgeries
  • Oral & Maxillofacial Surgeries
  • Delayed Union & Non-union Bone Fractures
  • Others
• GLOBAL: Projected Revenue by End-User (2020-2029; $Millions)
  • Hospitals & Clinics
  • Specialty Orthopedic & Spine Centers
  • Ambulatory Surgical Centers (ASCs)

CHAPTER - 4: Key Regions Overview

• North America: Projected Revenue of Bone Growth Products Market (2020-2029; $Millions)
  • Projected Revenue of Bone Growth Products Market in US
  • Projected Revenue of Bone Growth Products Market in Canada
• Europe: Projected Revenue of Bone Growth Products Market (2020-2029; $Millions)
  • Projected Revenue of Bone Growth Products Market in Germany
  • Projected Revenue of Bone Growth Products Market in France
  • Projected Revenue of Bone Growth Products Market in UK
  • Projected Revenue of Bone Growth Products Market in Italy
  • Projected Revenue of Bone Growth Products Market in Spain
• APAC: Projected Revenue of Bone Growth Products Market (2020-2029; $Millions)
  • Projected Revenue of Bone Growth Products Market in China
  • Projected Revenue of Bone Growth Products Market in Japan
  • Projected Revenue of Bone Growth Products Market in India
  • Projected Revenue of Bone Growth Products Market in Australia
  • Projected Revenue of Bone Growth Products Market in South Korea
• Latin America: Projected Revenue of Bone Growth Products Market (2020-2029; $Millions)
  • Projected Revenue of Bone Growth Products Market in Brazil
  • Projected Revenue of Bone Growth Products Market in Mexico
  • Projected Revenue of Bone Growth Products Market in Argentina
• Middle East & Africa: Projected Revenue of Bone Growth Products Market (2020-2029; $Millions)
  • Projected Revenue of Bone Growth Products Market in Turkey
  • Projected Revenue of Bone Growth Products Market in Saudi Arabia
  • Projected Revenue of Bone Growth Products Market in South Africa

CHAPTER - 5: Bone Growth Products Market Prospects & Opportunities

• Bone Growth Products Market Opportunities & Trends
• Bone Growth Products Market Drivers
• Bone Growth Products Market Constraints

CHAPTER - 6: Bone Growth Products Industry Overview

• Bone Growth Products Market - Competitive Landscape
• Bone Growth Products Market - Key Vendor Profiles
• Bone Growth Products Market - Other Prominent Vendors
• Bone Growth Products Market - Key Strategic Recommendations

CHAPTER - 7: Appendix

• Research Methodology
• Abbreviations
• About Arizton

LIST OF EXHIBITS

Exhibit 1: Projected Revenues of Global Bone Growth Products (2020-2029, $ MN)

Exhibit 2: Market Size & Forecast - Bone Growth Stimulator Devices (2020-2029, $ MN)

Exhibit 3: Market Size & Forecast - Bone Morphogenetic Protein (2020-2029, $ MN)

Exhibit 4: Market Size & Forecast - Platelet Rich Plasma (2020-2029, $ MN)

Exhibit 5: Market Size & Forecast - Spinal Fusion Surgeries (2020-2029, $ MN)

Exhibit 6: Market Size & Forecast - Oral & Maxillofacial Surgeries (2020-2029, $ MN)

Exhibit 7: Market Size & Forecast - Delayed Union & Non-union Bone Fractures (2020-2029, $ MN)

Exhibit 8: Market Size & Forecast - Others (2020-2029, $ MN)

Exhibit 9: Market Size & Forecast - Hospitals & Clinics (2020-2029, $ MN)

Exhibit 10: Market Size & Forecast - Specialty Orthopedic & Spine Centers (2020-2029, $ MN)

Exhibit 11: Market Size & Forecast - Ambulatory Surgical Centers (ASCs) (2020-2029, $ MN)

Exhibit 12: Projected Revenues of Bone Growth Products in North America (2020-2029, $ MN)

Exhibit 13: Projected Revenues of Bone Growth Products in the US (2020-2029, $ MN)

Exhibit 14: Projected Revenues of Bone Growth Products in Canada (2020-2029, $ MN)

Exhibit 15: Projected Revenues of Bone Growth Products in Europe (2020-2029, $ MN)

Exhibit 16: Projected Revenues of Bone Growth Products in Germany (2020-2029, $ MN)

Exhibit 17: Projected Revenues of Bone Growth Products in France (2020-2029, $ MN)

Exhibit 18: Projected Revenues of Bone Growth Products in the UK (2020-2029, $ MN)

Exhibit 19: Projected Revenues of Bone Growth Products in Italy (2020-2029, $ MN)

Exhibit 20: Projected Revenues of Bone Growth Products in Spain (2020-2029, $ MN)

Exhibit 21: Projected Revenues of Bone Growth Products in APAC (2020-2029, $ MN)

Exhibit 22: Projected Revenues of Bone Growth Products in China (2020-2029, $ MN)

Exhibit 23: Projected Revenues of Bone Growth Products in Japan (2020-2029, $ MN)

Exhibit 24: Projected Revenues of Bone Growth Products in India (2020-2029, $ MN)

Exhibit 25: Projected Revenues of Bone Growth Products in Australia (2020-2029, $ MN)

Exhibit 26: Projected Revenues of Bone Growth Products in South Korea (2020-2029, $ MN)

Exhibit 27: Projected Revenues of Bone Growth Products in Latin America (2020-2029, $ MN)

Exhibit 28: Projected Revenues of Bone Growth Products in Brazil (2020-2029, $ MN)

Exhibit 29: Projected Revenues of Bone Growth Products in Mexico (2020-2029, $ MN)

Exhibit 30: Projected Revenues of Bone Growth Products in Argentina (2020-2029, $ MN)

Exhibit 31: Projected Revenues of Bone Growth Products in the MEA (2020-2029, $ MN)

Exhibit 32: Projected Revenues of Bone Growth Products in Turkey (2020-2029, $ MN)

Exhibit 33: Projected Revenues of Bone Growth Products in Saudi Arabia (2020-2029, $ MN)

Exhibit 34: Projected Revenues of Bone Growth Products in South Africa (2020-2029, $ MN)

LIST OF TABLES

LIST OF TABLES

Table 1: Projected Revenues of Global Bone Growth Products Market (2020-2029, $ MN)

Table 2: Global Bone Growth Products Market by Product (2020-2029, %)

Table 3: Global Bone Growth Products Market by Product (2020-2029, $ MN)

Table 4: Global Bone Growth Products Market by Application (2020-2029, %)

Table 5: Global Bone Growth Products Market by Application (2020-2029, $ MN)

Table 6: Global Bone Growth Products Market by End-User (2020-2029, %)

Table 7: Global Bone Growth Products Market by End-User (2020-2029, $ MN)

Table 8: Global Bone Growth Products Market by Geography (2020-2029, %)

Table 9: Global Bone Growth Products Market by Geography (2020-2029, $ MN)