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市场调查报告书
商品编码
1400507
全球细胞/基因疗法 CDMO 市场(2024 年版):按类型、应用、适应症、地区和国家、市场考察和预测进行分析(2024-2029 年)Global Cell and Gene Therapy CDMO Market (2024 Edition): Analysis By Type (Cell Therapy, Gene Therapy, Gene-modified Cell Therapies), Application (Clinical, Pre-clinical), Indication, By Region, By Country: Market Insights and Forecast (2024-2029) |
全球细胞和基因治疗 CDMO 市场规模预计将从 2022 年的 25.4 亿美元成长,2024-2029 年预测期间复合年增长率为 30.75%。在细胞和基因疗法不断进步的推动下,市场呈现健康成长和不断增长的需求。由于治疗范围的扩大和有利的法规环境,该市场预计将继续扩大,因为它在各种疾病的创新治疗方法的开发和商业化中发挥关键作用。在行业参与者大量投资的推动下,市场预计将出现巨大增长。
全球细胞和基因治疗产品线正在不断扩大,涵盖癌症、罕见疾病和遗传性疾病等广泛的治疗领域。随着越来越多的治疗方法通过临床试验并走向商业化,对製造、製程开发和扩大规模的 CDMO 服务的需求不断增加。
全球细胞和基因疗法 CDMO 组织正在扩大,这是推动细胞和基因疗法在全球范围内全面扩张的主要因素之一。随着全球对先进细胞和基因疗法的需求增加,CDMO 正在各地积极建立生产设施,以满足生物技术和製药公司不断变化的需求。如今,CDMO已成为药品生产不可或缺的一部分。在过去的十年中,由于併购环境更加活跃,CDMO 的影响力增加。目前有超过 600 个活跃的受託製造厂商(CDMO) 为本地和国际市场提供服务。 CDMO 提供特定的专业知识,帮助「大型製药企业」和小型发明家将其产品快速推向市场。
生技药品的崛起可以从对新生技药品生产设施进行大量投资的 CDMO 数量看出。这些公司包括勃林格殷格翰(投资8.27亿美元)、三星生物製品(投资17亿美元)、Lonza(投资9.35亿美元)、Fujifilm Diosynth Biotechnologies(投资20亿美元)等。
此外,在全球范围内扩张使 CDMO 能够满足当地的监管需求,提供客製化的製造解决方案,并增加需要其服务的客户的可及性。 CDMO 在全球主要市场的存在使他们能够提供更具适应性和敏捷性的解决方案。这将加速基因和细胞疗法的开发和全球商业化。
限制市场成长的突出因素之一是病毒载体的高製造成本。病毒载体作为将治疗基因传递至目标细胞的载体,对于基因和细胞疗法的发展至关重要。病毒载体的生产是一个复杂的过程,通常需要专门的技术、严格的品管标准和专门的设备。
目前有五种类型的病毒载体用于基因治疗。 AAV 的市场占有率最高,其次是慢病毒、腺病毒、单纯疱疹病毒和逆转录病毒。根据 Roland Berger Insights 的数据,单给药载体的製造成本可能为 100 万美元至 200 万美元,预计每批次为 300 万美元至 700 万美元。因此,病毒载体的高製造成本阻碍了细胞和基因疗法的广泛商业化和可用性。
该报告审视了全球细胞和基因治疗 CDMO 市场,并提供了包括市场规模和预测、区域和細項分析以及主要趋势和机会在内的资讯。
Azoth Analytics has released a research report titled "Global Cell and Gene Therapy CDMO Market (2024 Edition)" which provides a complete analysis of the Global Cell and Gene Therapy CDMO Market industry in terms of market segmentation by Type (Cell Therapy, Gene Therapy, Gene-modified Cell Therapies), Application (Clinical, Pre-clinical), Indication (Oncology Diseases, Infectious Diseases, Neurological Disorder, Others) for the historical period of 2019-2022, estimates of 2023 and the forecast for 2024-2029.
The Global Cell and Gene Therapy CDMO market valued at USD 2.54 billion in 2022 is expected to grow at a CAGR of 30.75% during the forecast period of 2024-2029. The global Cell and Gene Therapy CDMO market has been experiencing robust growth and escalating demand, propelled by continuous advancements in cell and gene therapies. With a broadening scope of therapeutic areas and a favourable regulatory environment, the global Cell and Gene Therapy CDMO market is poised for sustained expansion as it plays a pivotal role in the development and commercialization of ground-breaking therapies for various diseases. The global Cell and Gene Therapy CDMO market is expected to grow at an extraordinary rate driven by significant investments from industry players.
The global pipeline of cell and gene therapies has been expanding, covering a wide range of therapeutic areas, including oncology, rare diseases, and genetic disorders. As more therapies advance through clinical trials and toward commercialization, the demand for CDMO services for manufacturing, process development, and scale-up increases.
Global CDMO organisations for cell and gene therapy are expanding, and this is one of the main factors propelling the global Cell and Gene Therapy's overall expansion. With the increasing global demand for advanced cell and gene therapies, CDMOs are proactively setting up production facilities in various locations to meet the changing demands of biotechnology and pharmaceutical companies. These days, CDMOs are essential to the manufacturing of pharmaceuticals. Over the past ten years, CDMOs have grown in prominence due to a more dynamic mergers and acquisition landscape. Serving both local and international markets, there are currently over 600 active Contract Development and Manufacturing Organizations (CDMOs). CDMOs provide specific expertise that helps both "Big Pharma" and smaller inventors to launch products sooner.
The rise of biologics is seen by the number of CDMOs making significant investments in brand-new biomanufacturing facilities. These companies include Boehringer Ingelheim (USD827M investment), Samsung Biologics (USD1.7B investment), Lonza (USD935M expansion), and Fujifilm Diosynth Biotechnologies (USD2B investment).
Additionally, by expanding globally, CDMOs can meet regional regulatory needs, provide customised manufacturing solutions, and improve accessibility for customers who need their services. CDMOs can provide more adaptable and responsive solutions by being present in important worldwide markets. This helps to speed up the development and global commercialization of gene and cell therapies.
One prominent factor restraining the growth of the global Cell and Gene Therapy CDMO market is the high cost of producing viral vectors. As carriers of therapeutic genes into target cells, viral vectors are essential to the development of gene and cell therapies. Viral vector production is a complex procedure that frequently involves specialized techniques, stringent quality control standards, and specialized facilities.
There are now five viral vectors in use for gene therapy. AAV have the biggest market share, followed by lentiviruses, adenoviruses, herpes simplex viruses and retroviruses. The vector manufacturing cost for a single dose might be as high as USD 1-2 million, given the expected price of USD 3-7 million per batch, according to Roland Berger Insights. Therefore, the high cost of producing viral vectors hampers cell and gene therapies from being widely commercialised and made accessible, which limits their uptake and hinders the expansion of the Cell and Gene CDMO market.
List of Tables
Table A1: Global Impact of Macro Economic Factors, By Region
Table A2: OXB's Internal Cell and Gene Therapy Pipeline
Table A3: Clinical AAV Gene Therapies for Genetic Neurological Disorders
Table A4: FDA NME Approvals, 2019-2022
Table A5: Drugs by Therapy Area
Table A6: Approved Gene, Cell, and RNA Therapies Globally, for Clinical Use
Table A7: Pipeline Therapies by Category
Table A8: Approved Gene, Cell, and RNA Therapies Globally, for Clinical Use
Table A9: Number of Therapies from Pre-clinical through Pre-registration
Table A10: Therapies in the Clinic (excludes preclinical development)
Table A11: Cell and Gene Therapy Landscape, by Region
Table A12: Landscape of Key Cell and Gene Therapy Service Providers
Table A13: United States Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A14: United States Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A15: United States Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A16: United States Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A17: United States Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A18: United States Cell and Gene Therapy CDMO Market, By Indication, By Value, 2023-2029 (USD Million)
Table A19: Canada Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A20: Canada Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A21: Canada Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A22: Canada Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A23: Canada Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A24: Canada Cell and Gene Therapy CDMO Market, By Indication, By Value, 2023-2029 (USD Million)
Table A25: Rest of Americas Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A26: Rest of Americas Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A27: Rest of Americas Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A28: Rest of Americas Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A29: Rest of Americas Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A30: Rest of Americas Cell and Gene Therapy CDMO Market, By Indication, By Value, 2023-2029 (USD Million)
Table A31: United Kingdom Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A32: United Kingdom Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A33: United Kingdom Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A34: United Kingdom Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A35: United Kingdom Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A36: United Kingdom Elevated Work Platform (MEWP) Market, By Indication, By Value, 2023-2029 (USD Million)
Table A37: Germany Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A38: Germany Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A39: Germany Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A40: Germany Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A41: Germany Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A42: Germany Cell and Gene Therapy CDMO Market, By Indication, By Value, 2023-2029 (USD Million)
Table A43: France Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A44: France Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A45: France Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A46: France Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A47: France Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A48: France Cell and Gene Therapy CDMO Market, By Indication, By Value, 2023-2029 (USD Million)
Table A49: Italy Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A50: Italy Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A51: Italy Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A52: Italy Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A53: Italy Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A54: Italy Cell and Gene Therapy CDMO Market, By Indication, By Value, 2023-2029 (USD Million)
Table A55: Rest of Europe Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A56: Rest of Europe Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A57: Rest of Europe Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A58: Rest of Europe Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A59: Rest of Europe Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A60: Rest of Europe Cell and Gene Therapy CDMO Market, By Indication, By Value, 2023-2029 (USD Million)
Table A61: China Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A62: China Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A63: China Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A64: China Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A65: China Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A66: China Cell and Gene Therapy CDMO Market, By Indication, By Value, 2023-2029 (USD Million)
Table A67: Japan Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A68: Japan Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A69: Japan Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A70: Japan Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A71: Japan Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A72: Japan Cell and Gene Therapy CDMO Market, By Indication, By Value, 2023-2029 (USD Million)
Table A73: South Korea Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A74: South Korea Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A75: South Korea Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A76: South Korea Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A77: South Korea Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A78: South Korea Cell and Gene Therapy CDMO Market, By Indication, By Value, 2023-2029 (USD Million)
Table A79: India Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A80: India Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A81: India Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A82: India Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A83: India Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A84: India Cell and Gene Therapy CDMO Market, By Indication, By Value, 2023-2029 (USD Million)
Table A85: Rest of Asia Pacific Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A86: Rest of Asia Pacific Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A87: Rest of Asia Pacific Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A88: Rest of Asia Pacific Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A89: Rest of Asia Pacific Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A90: Rest of Asia Pacific Cell and Gene Therapy CDMO Market, By Indication, By Value, 2023-2029 (USD Million)
Table A91: Oxford Biomedica Financials, 2020-2022
Table A92: Lonza Group AG Financials, 2020-2022
Table A93: Catalent, Inc. Financials, 2020-2022
Table A94: Samsung Biologics Financials, 2020-2022
Table A95: WuXi Biologics Financials, 2020-2022
Table A96: Pfizer CentreOne Financials, 2020-2022
Table A97: Danaher Corporation Financials, 2020-2022
Table A98: Thermo Fisher Scientific Inc. Financials, 2020-2022
Table A99: Charles River Laboratories International, Inc. Financials, 2020-2022
Table A100: Novartis AG Financials, 2020-2022