全球活性药物成分 (API) 市场

全球活性药物成分（API）市场规模预计将从2023年的2,478亿美元成长到2029年的3,479亿美元，预测期内复合年增长率为5.9%。

在製造业中，化学合成产业预计将从2023年的1,813亿美元成长到2029年的2,461亿美元，复合年增长率为5.4%。生技产业预计将从 2023 年的 665 亿美元成长到 2029 年的 1,017 亿美元，复合年增长率为 7.4%。

本报告调查了全球活性药物成分（API）市场，并提供了市场概况、市场影响因素和市场机会分析、法律制度、新兴技术和技术发展趋势、市场规模趋势和预测以及各种详细总结。按细分和地区分析、竞争状况、主要企业概况等

目录

第一章执行摘要

• 市场展望
• 调查范围
• 市场概况

第二章 市场概况

• API定义
• 全球原料药供应链
• 原料药製造方法
• API生产：合成途径
• 製造方法

第三章市场动态

• 市场动态简介
• 市场驱动因素
• 医药需求富弹性
• 学名药的采用增加
• 转向更复杂的化学品
• 生物製药市场的成长
• API 製造的进步
• 政府支持
• 市场限制因素
• 严格的法规和合规要求
• 非专利药产业的定价压力
• 缺乏熟练的专业人员
• 市场趋势
• 对复杂 API 的需求增加
• 区域多角化和供应链弹性
• 连续流製造
• 一次性技术的扩展
• 扩大 API 製造的永续性实践
• 外包和 CDMO伙伴关係关係的增加

第四章新兴科技与发展

• 用于复杂合成 API 生产的生物催化剂
• 人工智慧和机器学习集成
• 柔性製造

第五章市场区隔分析

• 细分细分
• API 市集：按製造商类型
• 内部和契约製造市场
• 商业市场
• API 市场：依製造方法分类
• 化学合成
• 生物技术
• API 市集：按分子类型
• 小分子原料药
• 高分子
• 地域分布
• API 市集：按地区
• 北美洲
• 欧洲
• 亚太地区
• 其他领域

第六章 竞争讯息

• 供应商情况
• 内部API製造商
• 契约製造製造商
• 商业原料药製造商
• 一般API：市场状况
• 创新API：市场情势
• 波特五力分析

第七章 附录

• 调查方法
• 来源
• 简称
• 公司简介
• AUROBINDO PHARMA
• DIVI'S LABORATORIES LTD.
• EUROAPI
• EVONIK INDUSTRIES AG
• LONZA
• PFIZER INC.
• SIEGFRIED HOLDING AG
• TEVA PHARMACEUTICAL INDUSTRIES LTD.
• THERMO FISHER SCIENTIFIC INC.
• WUXI APPTEC

The global market for active pharmaceutical ingredients (APIs) is estimated to increase from $247.8 billion in 2023 to reach $347.9 billion by 2029, at a compound annual growth rate (CAGR) of 5.9% from 2024 through 2029.

The chemical synthesis market for APIs is estimated to increase from $181.3 billion in 2023 to reach $246.1 billion by 2029, at a CAGR of 5.4% from 2024 through 2029.

The biotech market for APIs is estimated to increase from $66.5 billion in 2023 to reach $101.7 billion by 2029, at a CAGR of 7.4% from 2024 through 2029.

Report Scope

This goal of this report is to impart in-depth knowledge of the global market for active pharmaceutical ingredients (APIs), in terms of both qualitative and quantitative data, to help readers assess the market landscape, develop business/growth strategies, and analyze their market position. BCC Research estimates market size for 2023 (the base year) and forecasts values for 2024 by the end of 2029. It is important to note that market size reflects the demand for APIs within a region or country rather than the API industry itself.

In this report, the API market is analyzed by manufacturer type, production method, molecule type, region and country. Industry growth trends, drivers, restraints and opportunities in the API market are also discussed in detail. The scope of the study is global.

Report Includes

• 64 data tables and 38 additional tables
• An analysis of the global markets for active pharmaceutical ingredients (APIs)
• Analyses of global market trends, with market revenue data from 2022 to 2023, estimates for 2024, forecast for 2025, and projected CAGRs through 2029
• Estimates of the size and revenue prospects of the global market, along with a market share analysis by origin, drug molecular entity type, manufacturer type, end use and region
• Facts and figures pertaining to the market dynamics, technical advances, API sources, production methods, route of synthesis, regulations, and the impact of macroeconomic variables
• A Porter's Five Forces model, and global supply chain and PESTLE analyses
• Patent activity featuring issues like patent expiry and its impact on the pharmaceutical market, and details of changes in pharmaceutical drug development
• Overview of sustainability trends and ESG developments, with emphasis on consumer attitudes, ESG score analysis, and the ESG practices of leading companies
• Analysis of the industry structure, including companies' market shares, strategic alliances, M&A activity and a venture funding outlook
• Company profiles of major players within the industry, including Pfizer Inc., Thermo Fisher Scientific Inc., EuroAPI, Lonza, Siegfried Holding AG, and Divi's Laboratories Ltd.

Table of Contents

Chapter 1 Executive Summary

• Market Outlook
• Scope of Report
• Market Summary

Chapter 2 Market Overview

• APIs Defined
• Global API Supply Chain
• API Production Methods
• API Production: Route of Synthesis
• Production Methods

Chapter 3 Market Dynamics

• Market Dynamics Snapshot
• Market Drivers
• Resilient Pharmaceutical Demand
• Increase in Adoption of Generics
• Shift to More Complex Chemical Entities
• Growth in the Biologics Market
• Advances in API Manufacturing
• Government Support
• Market Restraints
• Strict Regulations and Compliance Requirements
• Pricing Pressure in the Generic API Industry
• Shortage of Skilled Professionals
• Market Trends
• Increasing Demand for Complex APIs
• Regional Diversification and Supply Chain Resilience
• Continuous Flow Manufacturing
• Expansion of Single-Use Technologies
• Growing Sustainability Practices in API Manufacturing
• Increased Outsourcing and CDMO Partnerships

Chapter 4 Emerging Technologies and Developments

• Biocatalysis for Complex Synthetic API Manufacturing
• Integration of AI and ML
• Flexible Manufacturing

Chapter 5 Market Segmentation Analysis

• Segmentation Breakdown
• API Market, by Manufacturer Type
• Captive and Contract Manufacturing Market
• Merchant Market
• API Market, by Production Method
• Chemical Synthesis
• Biotech
• API Market, by Molecule Type
• Small-Molecule APIs
• Large Molecule
• Geographic Breakdown
• API Market, by Region
• North America
• Europe
• Asia-Pacific
• Rest of the World

Chapter 6 Competitive Intelligence

• Supplier Landscape
• Captive Manufacturers
• Contract Manufacturers
• Merchant Manufacturers
• Generic API Market Landscape
• Innovative API Market Landscape
• Porter's Five Forces Analysis

Chapter 7 Appendix

• Methodology
• Sources
• Abbreviations
• Company Profiles
• AUROBINDO PHARMA
• DIVI'S LABORATORIES LTD.
• EUROAPI
• EVONIK INDUSTRIES AG
• LONZA
• PFIZER INC.
• SIEGFRIED HOLDING AG
• TEVA PHARMACEUTICAL INDUSTRIES LTD.
• THERMO FISHER SCIENTIFIC INC.
• WUXI APPTEC

List of Tables

• Summary Table : Global Market for APIs, by Production Method, Through 2029
• Table 1 : Regulatory Requirements of GMP and Supply Chain Integrity for APIs
• Table 2 : Recent Spin-offs and Separations of API Companies
• Table 3 : Biocatalysis in API Production: Benefits and Challenges
• Table 4 : Global Market for APIs, by Manufacturer Type, Through 2029
• Table 5 : Global Market for Captive and Contract Manufacturer APIs, by Region, Through 2029
• Table 6 : Global Market for Merchant APIs, by Region, Through 2029
• Table 7 : Global Market for APIs, by Production Method, Through 2029
• Table 8 : Biotech Production Methods: Attributes and Applications
• Table 9 : Global Market for Biotech APIs, by Production Method, Through 2029
• Table 10 : Global Market for APIs, by Molecule Type, Through 2029
• Table 11 : Characteristics of Small Molecules
• Table 12 : Global Market for Small-Molecule APIs, by Type, Through 2029
• Table 13 : Global Market for Small-Molecule APIs, by Manufacturer Type, Through 2029
• Table 14 : Characteristics of Large Molecules/Biologics
• Table 15 : Global Market for Large-Molecule APIs, by Type, Through 2029
• Table 16 : Global Market for Large-Molecule APIs, by Manufacturer Type, Through 2029
• Table 17 : Global Market for APIs, by Region, Through 2029
• Table 18 : North American Market for APIs, by Manufacturer Type, Through 2029
• Table 19 : North American Market for APIs, by Production Method, Through 2029
• Table 20 : North American Market for APIs, by Molecule Type, Through 2029
• Table 21 : North American Market for APIs, by Country, Through 2029
• Table 22 : U.S. Market for APIs, by Production Method, Through 2029
• Table 23 : U.S. Market for APIs, by Molecule Type, Through 2029
• Table 24 : Canadian Market for APIs, by Production Method, Through 2029
• Table 25 : Canadian Market for APIs, by Molecule Type, Through 2029
• Table 26 : Mexican Market for APIs, by Production Method, Through 2029
• Table 27 : Mexican Market for APIs, by Molecule Type, Through 2029
• Table 28 : European Market for APIs, by Manufacturer Type, Through 2029
• Table 29 : European Market for APIs, by Production Method, Through 2029
• Table 30 : European Market for APIs, by Molecule Type, Through 2029
• Table 31 : European Market for APIs, by Country, Through 2029
• Table 32 : German Market for APIs, by Production Method, Through 2029
• Table 33 : German Market for APIs, by Molecule Type, Through 2029
• Table 34 : French Market for APIs, by Production Method, Through 2029
• Table 35 : French Market for APIs, by Molecule Type, Through 2029
• Table 36 : U.K. Market for APIs, by Production Method, Through 2029
• Table 37 : U.K. Market for APIs, by Molecule Type, Through 2029
• Table 38 : Italian Market for APIs, by Production Method, Through 2029
• Table 39 : Italian Market for APIs, by Molecule Type, Through 2029
• Table 40 : Spanish Market for APIs, by Production Method, Through 2029
• Table 41 : Spanish Market for APIs, by Molecule Type, Through 2029
• Table 42 : Rest of European Market for APIs, by Production Method, Through 2029
• Table 43 : Rest of European Market for APIs, by Molecule Type, Through 2029
• Table 44 : Asia-Pacific Market for APIs, by Manufacturer Type, Through 2029
• Table 45 : Asia-Pacific Market for APIs, by Production Method, Through 2029
• Table 46 : Asia-Pacific Market for APIs, by Molecule Type, Through 2029
• Table 47 : Asia-Pacific Market for APIs, by Country, Through 2029
• Table 48 : Chinese Market for APIs, by Production Method, Through 2029
• Table 49 : Chinese Market for APIs, by Molecule Type, Through 2029
• Table 50 : Japanese Market for APIs, by Production Method, Through 2029
• Table 51 : Japanese Market for APIs, by Molecule Type, Through 2029
• Table 52 : Indian Market for APIs, by Production Method, Through 2029
• Table 53 : Indian Market for APIs, by Molecule Type, Through 2029
• Table 54 : Rest of APAC Market for APIs, by Production Method, Through 2029
• Table 55 : Rest of APAC Market for APIs, by Molecule Type, Through 2029
• Table 56 : RoW Market for APIs, by Manufacturer Type, Through 2029
• Table 57 : RoW Market for APIs, by Production Method, Through 2029
• Table 58 : RoW Market for APIs, by Molecule Type, Through 2029
• Table 59 : RoW Market for APIs, by Country, Through 2029
• Table 60 : Key API Manufacturers
• Table 61 : Report Sources
• Table 62 : Abbreviations Used in this Report
• Table 63 : Aurobindo Pharma: Company Snapshot
• Table 64 : Aurobindo Pharma: Financial Performance, FY 2023 and 2024
• Table 65 : Aurobindo Pharma: Product Portfolio
• Table 66 : Aurobindo Pharma: News/Key Developments, 2022-2024
• Table 67 : Divi's Laboratories Ltd.: Company Snapshot
• Table 68 : Divi's Laboratories Ltd.: Financial Performance, FY 2023 and 2024
• Table 69 : Divi's Laboratories Ltd.: Product Portfolio
• Table 70 : EUROAPI: Company Snapshot
• Table 71 : EUROAPI: Financial Performance, FY 2022 and 2023
• Table 72 : EUROAPI: Product Portfolio
• Table 73 : EUROAPI: News/Key Developments, 2022-2024
• Table 74 : Evonik Industries AG: Company Snapshot
• Table 75 : Evonik Industries AG: Financial Performance, FY 2022 and 2023
• Table 76 : Evonik Industries AG: Product Portfolio
• Table 77 : Evonik Industries AG: News/Key Developments, 2022-2024
• Table 78 : Lonza: Company Snapshot
• Table 79 : Lonza: Financial Performance, FY 2022 and 2023
• Table 80 : Lonza: Product Portfolio
• Table 81 : Lonza: News/Key Developments, 2022-2024
• Table 82 : Pfizer Inc.: Company Snapshot
• Table 83 : Pfizer Inc.: Financial Performance, FY 2022 and 2023
• Table 84 : Pfizer Inc: Product Portfolio
• Table 85 : Pfizer Inc.: News/Key Developments, 2022-2024
• Table 86 : Siegfried Holding AG: Company Snapshot
• Table 87 : Siegfried Holding AG: Financial Performance, FY 2022 and 2023
• Table 88 : Siegfried Holding AG: Product Portfolio
• Table 89 : Siegfried Holding AG: News/Key Developments, 2022-2024
• Table 90 : Teva Pharmaceutical Industries Ltd.: Company Snapshot
• Table 91 : Teva Pharmaceutical Industries Ltd.: Financial Performance, FY 2022 and 2023
• Table 92 : Teva Pharmaceutical Industries Ltd.: Product Portfolio
• Table 93 : Teva Pharmaceutical Industries Ltd.: News/Key Developments, 2022-2024
• Table 94 : Thermo Fisher Scientific Inc.: Company Snapshot
• Table 95 : Thermo Fisher Scientific Inc.: Financial Performance, FY 2022 and 2023
• Table 96 : Thermo Fisher Scientific Inc.: Product Portfolio
• Table 97 : Thermo Fisher Scientific Inc.: News/Key Developments, 2023 and 2024
• Table 98 : WuXi AppTec: Company Snapshot
• Table 99 : WuXi AppTec: Financial Performance, FY 2022 and 2023
• Table 100 : WuXi AppTec: Product Portfolio
• Table 101 : WuXi AppTec: News/Key Developments, 2022-2024

List of Figures

• Summary Figure : Global Market Shares of APIs, by Production Method, 2023
• Figure 1 : End-to-End Pharmaceutical Supply Chain
• Figure 2 : API Market Supply Chain
• Figure 3 : Chemical Synthetic Process
• Figure 4 : Schematic Representation of Biological Production Process for APIs
• Figure 5 : Market Dynamics of Active Pharmaceutical Ingredients (APIs)
• Figure 6 : U.S. FDA ANDA Approvals, by Fiscal Year, 2020-2023
• Figure 7 : Share of U.S. FDA ANDA Approvals, by Generic Drug Type, 2020-2023
• Figure 8 : Share of Drug Molecules Approved by the FDA, by Molecule Type, 2016 to 2023
• Figure 9 : Novel Drugs Approved by the FDA, by Drug Type, 2018-2023
• Figure 10 : Global Market Shares of APIs, by Manufacturer Type, 2023
• Figure 11 : Global Market Shares of Captive and Contract Manufacturer APIs, by Region, 2023
• Figure 12 : Global Market Shares of Merchant APIs, by Region, 2023
• Figure 13 : Global Market Shares of APIs, by Production Method, 2023
• Figure 14 : Global Market Shares of Biotech APIs, by Production Method, 2023
• Figure 15 : Global Market Shares of APIs, by Molecule Type, 2023
• Figure 16 : Global Market Shares of Small-Molecule APIs, by Type, 2023
• Figure 17 : Global Market Shares of Small-Molecule APIs, by Manufacturer Type, 2023
• Figure 18 : Global Market Shares of Large-Molecule APIs, by Type, 2023
• Figure 19 : Global Market Shares of Large-Molecule APIs, by Manufacturer Type, 2023
• Figure 20 : Global Market Shares of APIs, by Region, 2023
• Figure 21 : Location of API Manufacturers Serving the U.S. Market, as of August 2023
• Figure 22 : Location of Finished Dosage Forms (FDF) Manufacturers Serving U.S. Market, as of August 2023
• Figure 23 : Sources of APIs Used in Medications Consumed in the U.S., Market Share by Dollar Value, 2021
• Figure 24 : Biopharmaceutical Manufacturing Facilities in the U.S., 2018-2023
• Figure 25 : North American Market for APIs, by Manufacturer Type, 2023
• Figure 26 : North American Market for APIs, by Production Method, 2023
• Figure 27 : North American Market for APIs, by Molecule Type, 2023
• Figure 28 : North American Market for APIs, by Country, 2023
• Figure 29 : European Market Shares of APIs, by Manufacturer Type, 2023
• Figure 30 : European Market Shares of APIs, by Production Method, 2023
• Figure 31 : European Market Shares of APIs, by Molecule Type, 2023
• Figure 32 : European Market Shares of APIs, by Country, 2023
• Figure 33 : Share of Manufacturing Sites of APIs for U.S. Market, by Country/Region, August 2019
• Figure 34 : India's Drug and Pharmaceuticals Exports, 2016/2017 to 2023/2024
• Figure 35 : Asia-Pacific Market Shares of APIs, by Manufacturer Type, 2023
• Figure 36 : Asia-Pacific Market Shares of APIs, by Production Method, 2023
• Figure 37 : Asia-Pacific Market Shares of APIs, by Molecule Type, 2023
• Figure 38 : Asia-Pacific Market Shares of APIs, by Country, 2023
• Figure 39 : RoW Market Shares of APIs, by Manufacturer Type, 2023
• Figure 40 : RoW Market Shares of APIs, by Production Method, 2023
• Figure 41 : RoW Market Shares of APIs, by Molecule Type, 2023
• Figure 42 : RoW Market Shares of APIs, by Country, 2023
• Figure 43 : Aurobindo Pharma: Revenue Share, by Business Unit, FY 2024
• Figure 44 : Aurobindo Pharma: Revenue Share: Revenue Share, by Country/Region, FY 2024
• Figure 45 : Divi's Laboratories Ltd.: Revenue Share, by Country/Region, FY 2024
• Figure 46 : EUROAPI: Revenue Share, by Business Unit, FY 2023
• Figure 47 : Evonik Industries AG: Revenue Share, by Business Unit, FY 2023
• Figure 48 : Evonik Industries AG: Revenue Share, by Region, FY 2023
• Figure 49 : Lonza: Revenue Share, by Business Unit, FY 2023
• Figure 50 : Lonza: Revenue Share, by Region, FY 2023
• Figure 51 : Pfizer Inc.: Revenue Share, by Business Unit, 2023
• Figure 52 : Pfizer Inc.: Revenue Share, by Country/Region, 2023
• Figure 53 : Siegfried Holding AG: Market Share, by Business Unit, 2023
• Figure 54 : Teva Pharmaceutical Industries Ltd.: Market Share, by Business Unit, 2023
• Figure 55 : Thermo Fisher Scientific Inc.: Market Share, by Business Unit, 2023
• Figure 56 : Thermo Fisher Scientific Inc.: Revenue Share, by Country/Region, 2023
• Figure 57 : WuXi AppTec: Revenue Share, by Business Unit, FY 2023
• Figure 58 : WuXi AppTec: Revenue Share, by Country/Region, FY 2023