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患者肿瘤组织移植 (PDX) 模型市场 - 全球市场规模、份额、趋势分析、机会和预测报告(2019-2029)Patient-Derived Xenograft Model Market - Global Size, Share, Trend Analysis, Opportunity and Forecast Report, 2019-2029, Segmented By Type ; By Tumor Type ; By End User ; By Region |
由于个人化医疗需求的不断增长和癌症发病率的上升,全球患者肿瘤组织移植(PDX)模型市场正在蓬勃发展。
领先的策略咨询和市场研究公司BlueWeave Consulting在最近的研究中估计,2022年全球患者肿瘤组织移植(PDX)模型市场规模为3.1256亿美元。 BlueWeave 预测,在 2023 年至 2029 年的预测期内,患者肿瘤组织植入 (PDX) 模型的全球市场规模将以 13.1% 的复合年增长率显着增长,到 2029 年将达到 6.5491 亿美元。全球患者肿瘤组织移植(PDX)模型市场的主要成长动力包括癌症患者数量的增加、药物研发活性化以及由于公共和私人对癌症研究的持续支持而对个体化药物的需求。需求旺盛等在临床前开发过程中,遵守美国FDA 的良好生产规范 (GMP) 至关重要。小型企业创新研究和小型企业技术转移津贴等政府倡议为临床前计画提供财务支援和指导。全球对 PDX 模型的需求不断增加,预计将简化模型选择和体内功效测试。 PDX 模型涉及将患者肿瘤组织直接移植到免疫力缺乏动物体内,保留重要的细胞-肿瘤相互作用,并已被证明可用于临床前药物测试和生物标记发现。免疫力缺乏大鼠的介绍有助于大鼠 PDX 模型的建立。扩大研发活动以及政府和私营部门对癌症研究的持续支持正在推动市场成长。然而,在分析期间,高成本、技术专长、道德问题预计将抑制整体市场的成长。
该报告的详细分析提供了有关全球患者肿瘤组织植入(PDX)模型市场的成长潜力、未来趋势和统计数据的资讯。我们也研究了推动市场总规模预测的因素。该报告致力于提供全球患者肿瘤组织植入(PDX)模型市场的最新技术趋势以及产业见解,以帮助决策者做出策略决策。此外,我们也分析了市场的成长动力、挑战和竞争力。
Global patient-derived xenograft (PDX) model market is flourishing because of the rising demand for personalized medicine and growing cancer incidence.
BlueWeave Consulting, a leading strategic consulting and market research firm, in its recent study, estimated the global patient-derived xenograft (PDX) model market size at USD 312.56 million in 2022. During the forecast period between 2023 and 2029, BlueWeave expects the global patient-derived xenograft (PDX) model market size to grow at a significant CAGR of 13.1% reaching a value of USD 654.91 million by 2029. Major growth drivers for the global patient-derived xenograft model market include an increasing cancer case, heightened pharmaceutical R&D, and rising demand for personalized medicines with continued support from public and private sectors for cancer research. Adherence to the US FDA Good Manufacturing Practices (GMPs) is crucial in preclinical development. Governments' initiatives, like Small Business Innovative Research and Small Business Technology Transfer Grants, offer financial support and guidance for preclinical programs. Anticipated PDX model demand is rising globally, simplifying model selection and in vivo efficacy trials. The PDX model involves direct implantation of patient tumor tissue into immune-compromised animals, preserving vital cell-tumor interactions and proving valuable in preclinical drug testing and biomarker discovery. The introduction of immunodeficient rats will facilitate PDX models in rats. Expanding R&D activities and consistent government and private sector support for cancer research drive market growth. However, high cost and technical expertise and ethical concerns are anticipated to restrain the overall market growth during the period in analysis.
The global patient-derived xenograft (PDX) model market refers to the market encompassing the use of specialized laboratory mice or other animals to implant human tumor tissues. These PDX models are created by directly transplanting cancerous tissue from a patient into an immune-deficient animal, preserving the essential interactions between human cancer cells and the surrounding microenvironment. They serve as vital tools for preclinical research in oncology, allowing scientists and researchers to study the behavior of human tumors in a more clinically relevant setting. The market includes the development, utilization, and supply of PDX models to facilitate drug testing, biomarker discovery, and co-clinical investigations in the quest for more effective cancer treatments and personalized medicine.
COVID-19 pandemic adversely affected the global patient-derived xenograft (PDX) model market. With lockdowns, restrictions on laboratory operations, and supply chain interruptions, research activities were temporarily halted or delayed. Access to resources and animal models required for PDX model development became constrained. Furthermore, prioritization of COVID-19 research led to a diversion of resources and funding. However, as the pandemic highlighted the importance of personalized medicine, it also emphasized the significance of PDX models in cancer research. As restrictions eased, the market rebounded, driven by the growing need for innovative cancer treatments and therapies.
Based on tumor type, the global patient-derived xenograft (PDX) model market is divided into Gastrointestinal Tumor Model, Gynecological Tumor Model, Respiratory Tumor Model, Urological Tumor Models, and Hematological Tumor Models segments. The respiratory tumor model segment holds the highest share in the global patient derived xenograft model market by tumor type, due to the increased prevalence of respiratory cancers worldwide, leading to a heightened focus on developing models to study these tumors. Lung cancer, for instance, remains a leading cause of cancer-related deaths globally, necessitating a robust platform for research. PDX models for respiratory tumors enable researchers to closely mimic and study these cancers in vivo, facilitating the development of innovative therapies and treatment strategies. This growing demand for effective respiratory tumor models propels the segment's dominance in the global PDX model market.
Major players operating in the global patient-derived xenograft (PDX) model market include: JSR Corporation, Wuxi Apptec, The Jackson Laboratory, Charles River Laboratories International, Inc., Taconic Biosciences, Inc., Oncodesign Precision Medicine, Inotiv, Inc., Pharmatest Services, Hera BioLabs, EPO Berlin-Buch GmbH, Xentech, Urosphere, Altogen Labs, and Abnova Corporation. To further enhance their market share, these companies employ various strategies, including mergers and acquisitions, partnerships, joint ventures, license agreements, and new product launches.
The in-depth analysis of the report provides information about growth potential, upcoming trends, and statistics of Global Patient-Derived Xenograft (PDX) Model Market. It also highlights the factors driving forecasts of total market size. The report promises to provide recent technology trends in Global Patient-Derived Xenograft (PDX) Model Market and industry insights to help decision-makers make sound strategic decisions. Furthermore, the report also analyzes the growth drivers, challenges, and competitive dynamics of the market.