Global Spinal Muscular Atrophy Treatment Market is valued at approximately USD 3.88 billion in 2021 and is anticipated to grow with a healthy growth rate of more than 18.6% over the forecast period 2022-2029. Spinal muscular atrophy (SMA) is a type of genetic disease that gradually destroys motor neurons that are the spinal cord and nerve cells in the brain stem. It also affects vital skeletal muscle activity including breathing, walking, speaking, and swallowing, which leads to muscle weakness and atrophy. The growing awareness regarding novel therapies, rising government support, coupled with increasing healthcare expenditure is primary factors that are fostering market growth across the globe.
The prevalence of spinal muscular atrophy is on the rise which is directly associated with the market demand across the globe. The National Organization for Rare Disorders (NORD) estimates that approximately 1 in 10,000 people worldwide suffer with spinal muscular atrophy (SMA). Likewise, according to the Spinal Muscular Atrophy Foundation, the condition is expected to affect 1 in every 6,000 to 10,000 newborns worldwide. Therefore, the growing incidences of the disorder are actively contributing to market demand, which, in turn, fosters the growth of the market. Moreover, the introduction of new product with high efficacies, as well as growing R&D investments are presenting various lucrative opportunities over the forecasting years. However, the high costs associated with the approved products and the dearth of skilled professionals are restricting the market growth throughout the forecast period of 2022-2029.
The key regions considered for the Global Spinal Muscular Atrophy Treatment Market study include Asia Pacific, North America, Europe, Latin America, and the Rest of the World. North America dominated the market in terms of revenue, owing to the growing spending on treatment products and the rising incidence of SMA disorders among the population. Whereas, the Asia Pacific is also expected to grow with the highest CAGR during the forecast period, owing to factors such as rising target populations, increasing expenditure on healthcare services, and geographic expansion of key players in the market space.
Major market players included in this report are:
- Biogen
- Novartis AG
- Ionis Pharmaceuticals Inc.
- Biohaven Pharmaceuticals
- F. Hoffmann-La Roche Ltd
- Cytokinetics
- Scholar Rock, Inc.
- PTC Therapeutics
- NMD PHARMA A/S
- Astellas Pharma Inc.
Recent Developments in the Market:
- In January 2022, Biogen and Ionis Pharmaceuticals, Inc., declare that the companies entered into licensing agreement with the aim of developing another experimental drug BIIB115 (an antisense oligonucleotide) to cure of patients with SMA. BIIB115 is an experimental preclinical-stage drug. The objective of this agreement is to expand Biogen's SMA drug portfolio.
- In May 2019, Novartis AG announced that its Zolgensma (onasemnogene abeparvovec-xioi) received an approval from the U.S. FDA for the first and only gene therapy for pediatric patients with spinal muscular atrophy (SMA).
Global Spinal Muscular Atrophy Treatment Market Report Scope:
- Historical Data: 2019-2020-2021
- Base Year for Estimation: 2021
- Forecast period: 2022-2029
- Report Coverage: Revenue forecast, Company Ranking, Competitive Landscape, Growth factors, and Trends
- Segments Covered: Product, Disease Type, Distribution Channel, Region
- Regional Scope: North America; Europe; Asia Pacific; Latin America; Rest of the World
- Customization Scope: Free report customization (equivalent up to 8 analyst's working hours) with purchase. Addition or alteration to country, regional & segment scope*
The objective of the study is to define market sizes of different segments & countries in recent years and to forecast the values to the coming years. The report is designed to incorporate both qualitative and quantitative aspects of the industry within countries involved in the study.
The report also caters detailed information about the crucial aspects such as driving factors & challenges which will define the future growth of the market. Additionally, it also incorporates potential opportunities in micro markets for stakeholders to invest along with the detailed analysis of competitive landscape and product offerings of key players. The detailed segments and sub-segment of the market are explained below:
By Product:
- Nusinersen
- Onasemnogen Abeparvovec
By Disease Type:
- Type 1 SMA
- Type 2 SMA
- Others
By Distribution Channel:
- Hospital Pharmacies
- Retail Pharmacies
- Others
By Region:
- North America
- U.S.
- Canada
- Europe
- UK
- Germany
- France
- Spain
- Italy
- ROE
- Asia Pacific
- China
- India
- Japan
- Australia
- South Korea
- RoAPAC
- Latin America
- Brazil
- Mexico
- RoLA
- Rest of the World
Table of Contents
Chapter 1. Executive Summary
- 1.1. Market Snapshot
- 1.2. Global & Segmental Market Estimates & Forecasts, 2019-2029 (USD Billion)
- 1.2.1. Spinal Muscular Atrophy Treatment Market, by Region, 2019-2029 (USD Billion)
- 1.2.2. Spinal Muscular Atrophy Treatment Market, by Product, 2019-2029 (USD Billion)
- 1.2.3. Spinal Muscular Atrophy Treatment Market, by Disease Type, 2019-2029 (USD Billion)
- 1.2.4. Spinal Muscular Atrophy Treatment Market, by Distribution Channel, 2019-2029 (USD Billion)
- 1.3. Key Trends
- 1.4. Estimation Methodology
- 1.5. Research Assumption
Chapter 2. Global Spinal Muscular Atrophy Treatment Market Definition and Scope
- 2.1. Objective of the Study
- 2.2. Market Definition & Scope
- 2.2.1. Scope of the Study
- 2.2.2. Industry Evolution
- 2.3. Years Considered for the Study
- 2.4. Currency Conversion Rates
Chapter 3. Global Spinal Muscular Atrophy Treatment Market Dynamics
- 3.1. Spinal Muscular Atrophy Treatment Market Impact Analysis (2019-2029)
- 3.1.1. Market Drivers
- 3.1.1.1. Increasing awareness regarding novel therapies
- 3.1.1.2. Growing prevalence of spinal muscular atrophy
- 3.1.2. Market Challenges
- 3.1.2.1. High costs associated with the approved products
- 3.1.2.2. Dearth of skilled professionals
- 3.1.3. Market Opportunities
- 3.1.3.1. Introduction of new product with high efficacies
- 3.1.3.2. Growing R&D investments
Chapter 4. Global Spinal Muscular Atrophy Treatment Market Industry Analysis
- 4.1. Porter's 5 Force Model
- 4.1.1. Bargaining Power of Suppliers
- 4.1.2. Bargaining Power of Buyers
- 4.1.3. Threat of New Entrants
- 4.1.4. Threat of Substitutes
- 4.1.5. Competitive Rivalry
- 4.2. Futuristic Approach to Porter's 5 Force Model (2019-2029)
- 4.3. PEST Analysis
- 4.3.1. Political
- 4.3.2. Economical
- 4.3.3. Social
- 4.3.4. Technological
- 4.4. Top investment opportunity
- 4.5. Top winning strategies
- 4.6. Industry Experts Prospective
- 4.7. Analyst Recommendation & Conclusion
Chapter 5. Risk Assessment: COVID-19 Impact
- 5.1. Assessment of the overall impact of COVID-19 on the industry
- 5.2. Pre COVID-19 and post COVID-19 Market scenario
Chapter 6. Global Spinal Muscular Atrophy Treatment Market, by Product
- 6.1. Market Snapshot
- 6.2. Global Spinal Muscular Atrophy Treatment Market by Product, Performance - Potential Analysis
- 6.3. Global Spinal Muscular Atrophy Treatment Market Estimates & Forecasts by Product 2019-2029 (USD Billion)
- 6.4. Spinal Muscular Atrophy Treatment Market, Sub Segment Analysis
- 6.4.1. Nusinersen
- 6.4.2. Onasemnogen Abeparvovec
Chapter 7. Global Spinal Muscular Atrophy Treatment Market, by Disease Type
- 7.1. Market Snapshot
- 7.2. Global Spinal Muscular Atrophy Treatment Market by Disease Type, Performance - Potential Analysis
- 7.3. Global Spinal Muscular Atrophy Treatment Market Estimates & Forecasts by Disease Type 2019-2029 (USD Billion)
- 7.4. Spinal Muscular Atrophy Treatment Market, Sub Segment Analysis
- 7.4.1. Type 1 SMA
- 7.4.2. Type 2 SMA
- 7.4.3. Others
Chapter 8. Global Spinal Muscular Atrophy Treatment Market, by Distribution Channel
- 8.1. Market Snapshot
- 8.2. Global Spinal Muscular Atrophy Treatment Market by Distribution Channel, Performance - Potential Analysis
- 8.3. Global Spinal Muscular Atrophy Treatment Market Estimates & Forecasts by Distribution Channel 2019-2029 (USD Billion)
- 8.4. Spinal Muscular Atrophy Treatment Market, Sub Segment Analysis
- 8.4.1. Hospital Pharmacies
- 8.4.2. Retail Pharmacies
- 8.4.3. Others
Chapter 9. Global Spinal Muscular Atrophy Treatment Market, Regional Analysis
- 9.1. Spinal Muscular Atrophy Treatment Market, Regional Market Snapshot
- 9.2. North America Spinal Muscular Atrophy Treatment Market
- 9.2.1. U.S. Spinal Muscular Atrophy Treatment Market
- 9.2.1.1. Product breakdown estimates & forecasts, 2019-2029
- 9.2.1.2. Disease Type breakdown estimates & forecasts, 2019-2029
- 9.2.1.3. Distribution Channel breakdown estimates & forecasts, 2019-2029
- 9.2.2. Canada Spinal Muscular Atrophy Treatment Market
- 9.3. Europe Spinal Muscular Atrophy Treatment Market Snapshot
- 9.3.1. U.K. Spinal Muscular Atrophy Treatment Market
- 9.3.2. Germany Spinal Muscular Atrophy Treatment Market
- 9.3.3. France Spinal Muscular Atrophy Treatment Market
- 9.3.4. Spain Spinal Muscular Atrophy Treatment Market
- 9.3.5. Italy Spinal Muscular Atrophy Treatment Market
- 9.3.6. Rest of Europe Spinal Muscular Atrophy Treatment Market
- 9.4. Asia-Pacific Spinal Muscular Atrophy Treatment Market Snapshot
- 9.4.1. China Spinal Muscular Atrophy Treatment Market
- 9.4.2. India Spinal Muscular Atrophy Treatment Market
- 9.4.3. Japan Spinal Muscular Atrophy Treatment Market
- 9.4.4. Australia Spinal Muscular Atrophy Treatment Market
- 9.4.5. South Korea Spinal Muscular Atrophy Treatment Market
- 9.4.6. Rest of Asia Pacific Spinal Muscular Atrophy Treatment Market
- 9.5. Latin America Spinal Muscular Atrophy Treatment Market Snapshot
- 9.5.1. Brazil Spinal Muscular Atrophy Treatment Market
- 9.5.2. Mexico Spinal Muscular Atrophy Treatment Market
- 9.5.3. Rest of Latin America Spinal Muscular Atrophy Treatment Market
- 9.6. Rest of The World Spinal Muscular Atrophy Treatment Market
Chapter 10. Competitive Intelligence
- 10.1. Top Market Strategies
- 10.2. Company Profiles
- 10.2.1. Biogen
- 10.2.1.1. Key Information
- 10.2.1.2. Overview
- 10.2.1.3. Financial (Subject to Data Availability)
- 10.2.1.4. Product Summary
- 10.2.1.5. Recent Developments
- 10.2.2. Novartis AG
- 10.2.3. Ionis Pharmaceuticals Inc.
- 10.2.4. Biohaven Pharmaceuticals
- 10.2.5. F. Hoffmann-La Roche Ltd
- 10.2.6. Cytokinetics
- 10.2.7. Scholar Rock, Inc.
- 10.2.8. PTC Therapeutics
- 10.2.9. NMD PHARMA A/S
- 10.2.10. Astellas Pharma Inc.
Chapter 11. Research Process
- 11.1. Research Process
- 11.1.1. Data Mining
- 11.1.2. Analysis
- 11.1.3. Market Estimation
- 11.1.4. Validation
- 11.1.5. Publishing
- 11.2. Research Attributes
- 11.3. Research Assumption