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基因治疗学和RNAi

市场调查报告书

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1424420

反义和 RNAi 疗法的全球市场：按技术、按应用、按给药途径、按地区

Global Antisense & RNAi Therapeutics Market, By Technology, By Application, By Route of Administration, By Geography

出版日期: 2024年01月12日 | 出版商:

Coherent Market Insights | 英文 175 Pages | 商品交期: 2-3个工作天内

价格

简介目录

反义和 RNAi 疗法的市场规模预计将从 2023 年的 54 亿美元增加到 2030 年的 146.6 亿美元，预测期内复合年增长率为 15.3%。

报告范围		报告详情
基准年	2022年	2023/2024年市场规模	54亿美元
实际资料	2018-2021	预测期	2023-2030
预测期间 2023/2024 至 2030/2031 年复合年增长率：	15.30%	2030/2031价值预测	146.6亿美元

图 1. 2023 年反义和 RNAi 疗法的全球市场占有率（按地区划分）

反义和 RNAi 疗法是指利用自然发生的过程来靶向和抑制特定基因表现的一类药物。这些药物透过与 mRNA 和基因组 DNA 高度特异性结合而发挥作用。这抑制了疾病相关蛋白的表达。反义和 RNAi 疗法市场由于其具有高特异性和较少副作用治疗各种疾病的潜力而正在显着增长。这包括病毒感染、癌症和遗传性疾病。随着许多候选药物透过临床试验取得进展，市场正见证大量的研发投资。此外，新的药物递送技术的发展扩大了反义和RNAi治疗药物的可能性，并有望应用于以前无法治疗的疾病。

市场动态：

反义和RNAi疗法是新型的基于核酸的疗法，旨在抑制致病基因的表达。它透过与 mRNA 转录物结合并抑制翻译或诱导 mRNA 降解来发挥作用。因此，选择性定序不必要的基因有望治疗各种遗传性疾病、癌症和病毒感染疾病。此技术利用短的合成核酸链，例如 DNA、RNA 或与目标 mRNA 互补的修饰版本。全球反义和 RNAi 治疗市场是由各种癌症、遗传性疾病和感染疾病在全球日益流行所推动的。 RNA标靶药物在多种疾病的临床试验中已被证明是安全有效的，推动了市场成长。此外，核苷酸药物递送系统（例如奈米颗粒）的不断进步正在促进这些治疗药物的细胞摄取并扩大其临床应用。然而，不断上升的研发成本以及与药物开发相关的潜在脱靶效应是市场相关人员面临的一些挑战。另一方面，随着各大品牌专利到期的临近，学名药或许还有出现的机会。此外，针对慢性疾病的新型RNAi药物平台的市场开拓预计将进一步刺激市场扩张。

本研究的主要特点

本报告对全球反义和RNAi治疗市场进行了详细分析，并列出了以2022年为基准年的预测期（2023-2030）的市场规模和复合年增长率。
它揭示了各个细分市场的潜在商机，并概述了该市场有吸引力的投资提案矩阵。
它还提供了有关市场驱动因素、限制因素、机会、新产品发布和核准、市场趋势、区域前景、主要企业采取的竞争策略等的重要考察。
根据公司亮点、产品系列、主要亮点、绩效和策略等参数对全球反义和 RNAi 治疗市场的主要企业进行了分析。
这些公司从事受管制物质的研发、製造和分销。
该报告的见解使行销人员和公司负责人能够就未来的产品发布、产品升级、市场扩张和行销策略做出明智的决策。
全球反义和 RNAi 治疗市场报告针对该行业的各个相关人员，如投资者、供应商、产品製造商、分销商、新进业者和财务分析师。
透过用于分析全球反义和 RNAi 治疗市场的各种策略矩阵，将促进相关人员的决策。

北美洲
美国
加拿大
欧洲
德国
英国
西班牙
法国
义大利
俄罗斯
其他欧洲国家
亚太地区
中国
印度
日本
澳洲
韩国
ASEAN
其他亚太地区
拉丁美洲
巴西
阿根廷
墨西哥
其他拉丁美洲
中东
海湾合作委员会国家
以色列
其他中东地区
非洲
南非
北非
中部非洲

第9章竞争形势

Benitec Biopharma Inc.
Silence Therapeutics
Ionis Pharmaceuticals, Inc
Bio-Path Holdings Inc.
Percheron Therapeutics Limited
GSK plc
Olix Pharmaceuticals, Inc.
Sanofi
Alnylam Pharmaceuticals, Inc.
Arbutus Biopharma

第10章

调查方法
关于出版商

简介目录

Product Code: CMI6545

The antisense & RNAi therapeutics market size is expected to reach US$ 14.66 Billion by 2030, from US$ 5.40 Billion in 2023, at a CAGR of 15.3% during the forecast period.

Report Coverage		Report Details
Base Year:	2022	Market Size in 2023/2024:	US$ 5.40 Bn
Historical Data for:	2018 to 2021	Forecast Period:	2023 - 2030
Forecast Period 2023/2024 to 2030/2031 CAGR:	15.30%	2030/2031 Value Projection:	US$ 14.66 Bn

Figure 1. Global Antisense & RNAi Therapeutics Market Share (%), by Region, 2023

Global Antisense & RNAi Therapeutics Market - IMG1

Antisense & RNAi therapeutics refer to a class of drugs that use naturally occurring processes to target and inhibit the expression of specific genes. They work by binding to mRNA or genomic DNA with high specificity. This inhibits the expression of disease-associated proteins. The antisense & RNAi therapeutics market is growing substantially due to its potential to treat various conditions with high specificity and few side effects. These include viral infections, cancers, genetic disorders, and others. The market is witnessing significant investments in R&D as many drug candidates are progressing through clinical trials. The development of novel drug delivery techniques is also extending the potential of antisense & RNAi therapeutics to target previously undruggable diseases.

Market Dynamics:

Antisense and RNAi therapeutics are novel nucleic acid-based therapeutics designed to inhibit the expression of disease-causing genes. They work by binding to mRNA transcripts, preventing translation, or inducing mRNA degradation. This offers promise for treating various genetic disorders, cancers, and viral infections by selectively silencing unwanted genes. The technology utilizes short synthetic strands of nucleic acids such as DNA, RNA, or modified versions that are complementary to the target mRNA. The global antisense & RNAi therapeutics market is driven by the growing prevalence of various cancers, genetic disorders, and infectious diseases worldwide. RNA-targeting drugs have demonstrated safety and efficacy in clinical trials for various conditions, boosting market growth. Moreover, continuous advancements in nucleotide drug delivery systems, such as nanoparticles, have enhanced intracellular uptake of these therapeutics, expanding their clinical applications. However, high research and development costs associated with drug development and potential off-target effects are some of the challenges faced by market players. Meanwhile, the upcoming patent expiries of major brands will provide opportunities for generic versions. In addition, the development of novel RNAi drug platforms targeting chronic diseases will further stimulate market expansion.

Key features of the study:

This report provides in-depth analysis of the global antisense & RNAi therapeutics market, and provides market size (US$ Billion) and compound annual growth rate (CAGR%) for the forecast period (2023-2030), considering 2022 as the base year
It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by key players
It profiles key players in the global antisense & RNAi therapeutics market based on the following parameters - company highlights, products portfolio, key highlights, financial performance, and strategies
Key companies covered as a part of this study include Benitec Biopharma Inc., Silence Therapeutics, Ionis Pharmaceuticals, Inc, Bio-Path Holdings Inc., Percheron Therapeutics Limited, GSK plc, Olix Pharmaceuticals, Inc., Sanofi, Alnylam Pharmaceuticals, Inc. and Arbutus Biopharma.
These companies are involved in the research, development, manufacturing, and distribution of controlled substances
Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
The global antisense & RNAi therapeutics market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global antisense & RNAi therapeutics market

Detailed Segmentation:

By Technology:
- RNA Interference
- Antisense RNA
By Application:
- Genetic Disease
- Cancer
- Infectious Disease
- Neurodegenerative Disorders
- Cardio Metabolic & Renal Disorders
- Ocular Disorders
- Respiratory Disorders
- Skin Disorders
- Others
By Route of Administration:
- Intravenous Injections
- Intrathecal Injections
- Subcutaneous Injections
- Others
By Region:
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East
- Africa
Top companies in Antisense & RNAi Therapeutics Market
- Benitec Biopharma Inc.
- Silence Therapeutics
- Ionis Pharmaceuticals, Inc
- Bio-Path Holdings Inc.
- Percheron Therapeutics Limited
- GSK plc
- Olix Pharmaceuticals, Inc.
- Sanofi
- Alnylam Pharmaceuticals, Inc.
- Arbutus Biopharma

1. Research Objectives and Assumptions

Research Objectives
Assumptions
Abbreviations

2. Market Purview

Report Description
- Market Definition and Scope
Executive Summary
- Market Snippet, By Technology
- Market Snippet, By Application
- Market Snippet, By Route of Administration
- Market Snippet, By Region
Coherent Opportunity Map (COM)

3. Market Dynamics, Regulations, and Trends Analysis

Market Dynamics
- Drivers
Promising Innovations in Drug Delivery Systems
- Restraints
High Manufacturing Cost of RNA Therapeutics
- Opportunities
Untapped Emerging Markets
Impact Analysis
Key Highlights
Regulatory Scenario
Product launch/Approvals
PEST Analysis
PORTER's Analysis
Merger and Acquisition Scenario

4. Antisense & RNAi Therapeutics Market - Impact of Coronavirus (COVID-19) Pandemic

COVID-19 Epidemiology
Economic Impact

5. Antisense & RNAi Therapeutics Market , By Technology, 2018-2030, (US$ Bn)

Introduction
- Market Share Analysis, 2023 and 2030 (%)
- Y-o-Y Growth Analysis, 2019 - 2030
- Segment Trends
RNA Interference
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Bn)
Antisense RNA
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Bn)

6. Antisense & RNAi Therapeutics Market , By Application, 2018-2030, (US$ Bn)

Introduction
- Market Share Analysis, 2023 and 2030 (%)
- Y-o-Y Growth Analysis, 2019- 2030
- Segment Trends
Genetic Disease
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)
Cancer
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)
Infectious Disease
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)
Neurodegenerative Disorders
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)
Cardio Metabolic & Renal Disorders
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)
Ocular Disorders
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)
Respiratory Disorders
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)
Skin Disorders
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)
Others
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)

7. Antisense & RNAi Therapeutics Market , By Route of Administration, 2018-2030, (US$ Bn)

Introduction
- Market Share Analysis, 2023 and 2030 (%)
- Y-o-Y Growth Analysis, 2019- 2030
- Segment Trends
Intravenous Injections
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)
Intrathecal Injections
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)
Subcutaneous Injections
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)
Others
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)

8. Antisense & RNAi Therapeutics Market , By Region, 2018-2030, (US$ Bn)

Introduction
- Market Share Analysis, By Country, 2023 and 2030 (%)
- Y-o-Y Growth Analysis, For Country 2019-2030
- Country Trends
North America
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, By Technology, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Application, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Route of Administration, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Country, 2018-2030,(US$ Bn)
U.S.
Canada
Europe
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, By Technology, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Application, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Route of Administration, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Country, 2018-2030,(US$ Bn)
Germany
U.K.
Spain
France
Italy
Russia
Rest of Europe
Asia Pacific
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, By Technology, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Application, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Route of Administration, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Country, 2018-2030,(US$ Bn)
China
India
Japan
Australia
South Korea
ASEAN
Rest of Asia Pacific
Latin America
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, By Technology, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Application, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Route of Administration, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Country, 2018-2030,(US$ Bn)
Brazil
Argentina
Mexico
Rest of Latin America
Middle East
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, By Technology, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Application, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Route of Administration, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Country, 2018-2030,(US$ Bn)
GCC Countries
Israel
Rest of Middle East
Africa
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, By Technology, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Application, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Route of Administration, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Country/Region , 2018-2030,(US$ Bn)
South Africa
North Africa
Central Africa

9. Competitive Landscape

Benitec Biopharma Inc.
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
Silence Therapeutics
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
Ionis Pharmaceuticals, Inc
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
Bio-Path Holdings Inc.
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
Percheron Therapeutics Limited
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
GSK plc
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
Olix Pharmaceuticals, Inc.
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
Sanofi
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
Alnylam Pharmaceuticals, Inc.
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
Arbutus Biopharma
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
Analyst Views

10. Section

Research Methodology
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反义和 RNAi 疗法的全球市场：按技术、按应用、按给药途径、按地区