阿柏西普中国市场（2022-2031）

自2018年阿柏西普进入中国市场以来，2018年阿柏西普在中国的销售额达到830万元，2018-2021年的复合年增长率为206%，2021年将达到2.38亿元。 2021 年，受 COVID-19 疫情影响，复合年增长率放缓至 116%，但随着疫情好转，预计 2023 年至 2026 年将恢復并增长。

截至 2022 年 7 月，拜耳股份公司是中国阿柏西普市场上唯一的製造商。不过，在中国，很多药企都在仿製阿柏西普，仿製药有望在未来五年内进入中国市场，但短期内，拜耳的原研产品会受到较大影响，不考虑给予。

本报告研究和分析了中国的阿柏西普，提供市场规模、製造商分析和市场预测。

第一章阿柏西普相关概念

• 阿柏西普的适应症
• 阿柏西普在中国的发展
• 阿柏西普在中国的政府批准
• COVID-19 对阿柏西普在中国销售的影响

第二章阿柏西普在中国的销售情况（2018-2021）

• 阿柏西普的销售
  • 总销售额
  • 按地区划分的销售额
• 阿柏西普销量
  • 总销量
  • 按地区划分的销售额
• 阿柏西普在中国的销售情况：按给药方法（2018-2021 年）
  • 眼内註射
  • 其他给药方式分析

第三章中国主要阿柏西普厂家分析（2018-2021）

• 主要阿柏西普製造商的市场份额分析
  • 市场份额调查：按销售额
  • 市场份额调查：按销量
• 拜耳公司
  • 公司简介
  • EYLEA（拜耳阿柏西普）在中国的销售情况

第四章中国各厂商阿柏西普价格（2021-2022）

• 拜耳公司 (EYLEA)
• 其他

第五章中国阿柏西普药物市场展望（2022-2031）

• 影响中国阿柏西普市场发展的因素
  • COVID-19 对中国阿柏西普市场的影响
  • 市场驱动因素和机遇
  • 市场威胁和挑战
• 市场规模预测
• 预测市场趋势

Aflibercept is an anti-VEGF drug, mainly used to treat neovascular age-related macular degeneration (wAMD), and other retinopathy caused by visual impairment. Aflibercept was jointly developed by Regeneron and Bayer. Regeneron has exclusive sales rights in the U.S. market, while Bayer obtains exclusive sales rights outside the U.S. Their Aflibercept, EYLEA was launched in China in 2018. By July 2022, Bayer AG is the only manufacturer in the Chinese Aflibercept market.

According to CRI's market research, after Aflibercept entered the Chinese market, the sales value of Aflibercept in China increased from CNY8.3 million in 2018 to CNY238 million in 2021. The annual growth rate in 2021 was 116%, which slowed down due to the COVID-19 epidemic. The CAGR of sales value of aflibercept in China is 206% from 2018 to 2021.

CRI analyzes that as the epidemic situation has been improved and the hospitals resume their operation, the sales of Aflibercept will have a recovery growth from 2023 to 2026. In addition, the sales will also increase due to market expansion. Currently, China has only approved two indications for Aflibercept, including treatment of wAMD and treatment of DME. However, Aflibercept had five approved indications globally, which means the sales will continue to grow as the number of indications expands. On the other hand, though the anti-VEGF ophthalmic drug market where Aflibercept belongs to accounts for the largest market share in the ophthalmology drug industry, the penetration rate for the anti-VEGF drug is still low. The penetration rate for the anti-VEGF drug is about 1% in China, while it exceeds 5% in the U.S. Since the market demand has not yet reached saturation, the sales will keep increasing. Besides, Aflibercept was included in the national medical insurance catalog at the beginning of 2020, so the price has been lowered, which reduces the burden on patients and will stimulate sales in the future.

Qilu Pharmaceutical, a local Chinese pharmaceutical company, received CDE (CENTER FOR DRUG EVALUATION, NMPA) approval for its marketing authorization application for aflibercept intravitreal injection in April 2022, which is the first biosimilar application for aflibercept in China.

According to CRI's market research, a number of other pharmaceutical companies in China are in the process of genericizing aflibercept, such as Clover Biopharmaceuticals' aflibercept intraocular injection, which is in the clinical phase of application, and Shandong Boan Biotechnology Co.

It is expected that the generic version of aflibercept will enter the Chinese market in the next five years, but it is unlikely to have a significant impact on Bayer's original drug in the short term.

Topics covered:

• The impact of COVID-19 on China's aflibercept market

• Sales value and volume of China's aflibercept 2016-2020

• Competitive landscape of China's aflibercept market

• Prices of aflibercept in China

• Prices of aflibercept in China by regions and manufacturers

• Analysis on factors affecting the development of China's aflibercept market

• Prospect of China's aflibercept market from 2021 to 2025

Table of Contents

1 Relevant Concepts of Aflibercept

• 1.1 Indications for Aflibercept
• 1.2 Development of Aflibercept in China
• 1.3 Governmental Approval of Aflibercept in China
• 1.4 The Impact of COVID-19 on Aflibercept sales in China

2 Sales of Aflibercept in China, 2018-2021

• 2.1 Sales Value of Aflibercept
  • 2.1.1 Overall Sales Value
  • 2.1.2 Sales Value by Region
• 2.2 Sales Volume of Aflibercept
  • 2.2.1 Overall Sales Volume
  • 2.2.2 Sales Volume by Region
• 2.3 Sales of Aflibercept by Dosage Form in China, 2018-2021
  • 2.3.1 Intraocular Injection
  • 2.3.2 Analysis of Other Dosage Forms

3 Analysis of Major Aflibercept Manufacturers in China, 2018-2021

• 3.1 Analysis of Market Share of Major Aflibercept Manufacturers
  • 3.1.1 Investigation on Market Share by Sales Value
  • 3.1.2 Investigation on Market Share by Sales volume
• 3.2 Bayer AG
  • 3.2.1 Enterprise Profile
  • 3.2.2 Sales of EYLEA (Bayer's Aflibercept) in China

4 Prices of Aflibercept for Different Manufacturers in China, 2021-2022

• 4.1 Bayer AG (EYLEA)
• 4.2 Others

5 Prospect of Chinese Aflibercept drug Market, 2022-2031

• 5.1 Influential Factors of Chinese Aflibercept Market Development
  • 5.1.1 The Impact of COVID-19 on Chinese Aflibercept Market
  • 5.1.2 Market Drivers and Opportunities
  • 5.1.3 Market Threats and Challenges
• 5.2 Forecast on Market Size
• 5.3 Forecast on Market Trend

List of Charts

• Chart Aflibercept Drugs Approved by Chinese Government, by 2022
• Chart Sales Value of Aflibercept in China, 2018-2021
• Chart Sales Value of Aflibercept in Regions of China, 2018-2021 (Unit: CNY thousand)
• Chart Sales Volume of Aflibercept in China, 2018-2021
• Chart Sales Volume of Aflibercept in Regions of China,2018-2021
• Chart Sales value and volume of aflibercept intravitreal injection in China 2018-2021
• Chart Market Share of Aflibercept Manufacturers by Sales Value in China, 2018-2021
• Chart Market Share of Aflibercept Manufacturers by Sales Volume in China, 2018-2021
• Chart Profile of Bayer AG
• Chart Sales Value of Bayer AG's Aflibercept in China, 2018-2021
• Chart Sales Volume of Bayer AG 's Aflibercept in China, 2018-2021
• Chart EYLEA sold in the Chinese market
• Chart Prices of BAYER AG's Aflibercept (EYLEA ®) in Parts of China, 2021
• Chart Forecast on sales of aflibercept in China 2022-2026