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市场调查报告书
商品编码
1776217
鼻腔给药:市场洞察·竞争情形·市场预测 (~2032年)Intranasal Drug Delivery - Market Insights, Competitive Landscape, and Market Forecast - 2032 |
预计鼻腔给药市场规模将从2024年的644.512亿美元成长至2032年的1042.4863亿美元,预测期内复合年增长率为6.24%。
此成长主要源自于慢性疾病盛行率的上升,包括神经系统疾病、呼吸系统疾病、严重过敏性疾病和眼科疾病。对快速起效、非侵入性给药方式的需求日益增长,也促进了市场扩张。尤其是鼻腔给药,其吸收迅速、给药便捷,有助于提高患者依从性和疗效。此外,各大公司加强研发投入与产品上市力度,加速了该领域的技术创新。这些发展推动了更有效率、更有针对性的鼻腔治疗方案的开发,使市场更具活力和竞争力。这些趋势为市场持续成长创造了有利环境,预计2025年至2032年间市场将强劲且稳定地扩张。
鼻腔给药市场动态:
根据世界卫生组织 (WHO) 2024年发布的数据,预计到2023年,全球将有约5,000万人患有癫痫,成为最常见的神经系统疾病之一。约80%的病例集中在中低收入国家,这些国家及时治疗的机会仍然有限。在这些地区,鼻腔给药是一种实用、快速起效且无需医疗监督的治疗方法,是一种有效的替代疗法。癫痫发病率的不断上升正在推动市场成长,鼻腔给药被用于治疗癫痫患者的急性发作。
同样,忧郁症仍然是一个全球性的健康问题。根据世界卫生组织估计,2023年全球将有2.8亿人患有忧郁症。鼻腔给药已成为治疗难治性忧郁症的有效方法,尤其是在门诊和急诊环境中,对快速缓解症状和便捷给药的需求日益增长。这促使对鼻腔给药解决方案的需求不断增长。
全球糖尿病负担也迅速增加。根据国际糖尿病联盟(2023年)的预测,预计2021年糖尿病患者人数将达到5.37亿,2030年将达到6.43亿,2045年将达到7.83亿。胰高血糖素等激素的创新鼻腔製剂提供了一种非侵入性、快速起效的注射疗法替代方案,并有助于控製糖尿病患者的急性低血糖,同时避免肝臟代谢。因此,糖尿病患者数量的增加正在推动鼻腔给药市场的成长。
全球糖尿病负担也迅速增加。根据国际糖尿病联盟 (IDF) 2023 年的数据,2021 年全球 20-79 岁成年人糖尿病患者人数为 5.37 亿,预计到 2030 年将增至 6.43 亿,到 2045 年将增至 7.83 亿。升糖素等激素的创新鼻腔製剂提供了一种非侵入性、快速起效的注射替代方案,避免了肝臟首过代谢,并有助于急性低血糖管理。因此,糖尿病患者的增加进一步推动了市场的成长。
慢性疼痛和偏头痛也影响着全球许多人。根据欧洲疼痛研究协会联合会 (2023) 的数据,到 2023 年,约有 1.5 亿欧洲人将遭受慢性疼痛的折磨。世界卫生组织估计,2021 年全球约有 31 亿人患有偏头痛和其他头痛疾病。用于治疗急性偏头痛发作的鼻腔给药药物因其快速起效且无需消化道,需求正在增加。
本报告研究了全球鼻腔给药市场,并提供了全面的概述、市场影响因素和机会分析、监管环境、市场规模趋势和预测、按细分市场、地区和主要国家/地区进行的详细分析、竞争格局以及主要公司的概况。
Intranasal Drug Delivery Market by Dosage Form (Spray, Drops and Liquids, Gels, and Powders), Container (Pressurized and Non-pressurized), System (Unit-dose Systems, Bi-Dose Systems, and Multi-dose Systems), Application (Respiratory Disorders, Neurological Disorders, Infectious Diseases, and Others), Distribution Channel (Hospital & Retail Pharmacies and Online Pharmacies), and Geography (North America, Europe, Asia-Pacific, and Rest of the World) is expected to grow at a steady CAGR forecast till 2032 owing to The growing prevalence of chronic diseases and increasing R&D activities and product launches by key players in the domain of intranasal drug delivery.
The intranasal drug delivery market was valued at USD 64,451.20 million in 2024, growing at a CAGR of 6.24% during the forecast period from 2025 to 2032 to reach USD 104,248.63 million by 2032. This growth is primarily driven by the rising prevalence of chronic diseases, including neurological, respiratory, severe allergic, and ophthalmic disorders. The increasing demand for rapid-onset, non-invasive drug administration methods is also contributing to market expansion, as intranasal delivery offers fast absorption and ease of use, key factors in enhancing patient compliance and therapeutic outcomes. Moreover, heightened R&D activities and a surge in product launches by key industry players are further accelerating innovation in the field. These advancements are creating a dynamic and competitive landscape, fostering the development of more efficient and targeted intranasal therapies. Together, these trends are shaping a favorable environment for the sustained growth of the intranasal drug delivery market, positioning it for robust and consistent expansion throughout the forecast period from 2025 to 2032.
Intranasal Drug Delivery Market Dynamics:
According to the World Health Organization (2024), in 2023, epilepsy affected approximately 50 million people worldwide, making it one of the most common neurological disorders. Notably, around 80% of these cases occurred in low- and middle-income countries, where access to timely treatment remains limited. In such settings, intranasal drug delivery provides a practical, fast-acting alternative that can be administered without medical supervision. Such growing cases of epilepsy are driving the market growth as intranasal drug delivery is used for the acute treatment of intermittent episodes of increased seizure activity in patients with epilepsy.
Similarly, depression remains a major global health concern. As per WHO (2023), in 2023, an estimated 280 million people worldwide were living with depression. Intranasal therapies emerged as effective treatments for treatment-resistant depression, offering rapid symptom relief and easy administration, especially in outpatient and emergency care environments thereby creating the demand for intranasal drug delivery solutions.
The global diabetes burden is also rising rapidly. According to the International Diabetes Federation (2023), in 2021, there were 537 million adults (aged 20-79) living with diabetes, a number projected to increase to 643 million by 2030 and 783 million by 2045. Innovative intranasal formulations of hormones like glucagon provide a non-invasive, fast-acting alternative to injectable therapies, helping manage acute hypoglycemia in diabetic patients while bypassing hepatic metabolism. Therefore, rising cases of diabetes are driving the growth of the intranasal drug delivery market.
Additionally, chronic pain and migraine continue to affect large populations worldwide. According to the European Pain Federation (2023), in 2023, approximately 150 million people in Europe suffered from chronic pain. Meanwhile, the WHO (2024), estimated that migraine and other headache disorders affected 3.1 billion people globally in 2021. The demand for intranasal drug delivery solutions is increasing due to rising cases of migraine as these devices manage acute migraine attacks, offering quick relief by bypassing the gastrointestinal tract.
According to NHS England (2023), approximately 5.4 million individuals received treatment for asthma in 2023, with around 160,000 new diagnoses recorded annually in the United Kingdom. This rising prevalence of asthma is a significant driver of growth in the intranasal drug delivery market. Intranasal delivery presents a promising approach for asthma management, offering advantages such as ease of administration, rapid onset of action, and the ability to bypass first-pass metabolism. These benefits not only improve patient compliance but also enhance therapeutic efficiency, further contributing to the growing adoption of intranasal drug delivery systems in the treatment of respiratory conditions like asthma.
Conditions like depression, epilepsy, chronic pain, diabetes, and respiratory disorders often require medications that are either rapidly metabolized by the liver or difficult to administer orally during acute episodes. Intranasal drug delivery offers key advantages in such cases, including rapid absorption, avoidance of first-pass hepatic metabolism, and reduced side effects due to the lower doses required. Therefore, the growing prevalence of chronic diseases such as neurological disorders, respiratory conditions, and diabetes is significantly driving the growth of the intranasal drug delivery market.
The intranasal drug delivery market is further propelled by ongoing product approvals and launches from key industry players, reinforcing innovation and expanding treatment options. For example, in February 2025, Lupin Limited announced it had received approval from the U.S. Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for Ipratropium Bromide Nasal Solution. This product is indicated for the symptomatic relief of rhinorrhea associated with both allergic and nonallergic perennial rhinitis in adults and children aged 6 years and older. Similarly, in April 2024, Amneal Pharmaceuticals received U.S. FDA approval for its Over-the-counter (OTC) Naloxone Hydrochloride Nasal Spray, intended for the emergency treatment of opioid overdose. These developments not only underscore the growing adoption of intranasal formulations but also highlight the increasing focus on accessibility, patient convenience, and rapid therapeutic response key factors fueling the market's sustained growth.
However, the complexities and limitations associated with the intranasal drug administration and stringent regulatory requirements for product approval, among others are some of the key constraints that may limit the growth of the intranasal drug delivery market.
Intranasal Drug Delivery Market Segment Analysis:
Intranasal Drug Delivery Market by Dosage Form (Spray, Drops and Liquids, Gels, and Powders), Container (Pressurized and Non-pressurized), System (Unit-dose Systems, Bi-Dose Systems, and Multi-dose Systems), Application (Respiratory Disorders, Neurological Disorders, Infectious Diseases, and Others), Distribution Channel (Hospital & Retail Pharmacies and Online Pharmacies), and Geography (North America, Europe, Asia-Pacific, and Rest of the World)
In the dosage form segment of the intranasal drug delivery market, the spray category is estimated to account for the largest market share in 2024. This robust growth is primarily driven by the increasing prevalence of respiratory diseases, severe allergic reactions, ophthalmic disorders, and neurological conditions, coupled with the multiple clinical and practical advantages offered by nasal sprays.
Nasal sprays are favored for their non-invasive, needle-free application, offering ease of administration and rapid onset of action are the factors that significantly enhance patient compliance and therapeutic efficiency. The nasal mucosa's highly vascularized and permeable surface enables efficient systemic absorption of drugs while bypassing the first-pass hepatic metabolism and avoiding gastrointestinal degradation. This leads to improved bioavailability, especially for drugs that are unstable or poorly absorbed through oral routes.
Moreover, nasal sprays are increasingly being utilized in the treatment of central nervous system (CNS) disorders. Their ability to deliver drugs via the olfactory and trigeminal nerve pathways allows for direct access to the brain, making them particularly effective in treating acute neurological conditions such as migraines, seizures, and opioid overdoses, where immediate therapeutic intervention is critical.
With the global burden of neurological diseases on the rise, leading pharmaceutical companies are intensifying their investments in research and development to introduce advanced intranasal spray formulations targeting these conditions. For example, in March 2023, Pfizer Inc. received FDA approval for ZAVZPRET(TM) (zavegepant), a CGRP receptor antagonist nasal spray indicated for the acute treatment of migraine, with or without aura, in adults. Similarly, in August 2023, Emergent BioSolutions launched NARCAN(R) Naloxone HCl Nasal Spray 4 mg, an over-the-counter (OTC) product designed for the emergency treatment of opioid overdose. These product innovations and regulatory milestones underscore the increasing clinical relevance of nasal sprays in both urgent care and chronic disease management. As such, the spray segment is poised for substantial expansion, driven by a convergence of therapeutic demand, technological advancement, and regulatory support.
Thus, the factors mentioned above are likely to boost the market segment and thereby increase the overall market of intranasal drug delivery across the globe.
North America is expected to dominate the overall intranasal drug delivery market:
North America is expected to hold the largest share of the intranasal drug delivery market in 2024, driven by several key factors. The region's dominance is primarily attributed to the rising prevalence of neurological, respiratory, and diabetes, which has created a growing demand for more effective and patient-friendly drug delivery solutions. Additionally, the increasing preference for rapid-onset therapies and the convenience of self-administration is significantly boosting the adoption of intranasal drug delivery systems across the region. Moreover, increase in regulatory approvals and new product launches by leading pharmaceutical companies with a strong pipeline of intranasal formulations, coupled with favorable healthcare infrastructure and awareness. Collectively, these factors are expected to sustain North America's leading position in the global market.
As per the data from the National Institute of Health (2023), in 2022, it was estimated that more than one in five adults were living with a mental illness (59.3 million) with 21 million people suffering from one major depressive disorder. Similarly, data from the Government of Canada (2023), in 2022, approximately 5 million people were suffering from mental disorders including major depressive disorders, anxiety, and seizures among others. Intranasal drug delivery devices with drugs are used for treatment-resistant depression and major depressive disorder with suicidal ideation.
According to the Centers for Disease Control and Prevention (2024), in 2022, approximately 2.9 million adults aged 18 and older in the U.S. reported having active epilepsy.
Additionally, data from the Anxiety & Depression Association of America (2022), revealed that 2 to 3% of individuals in the country experienced panic disorder, with women being twice as likely to be affected as men. Furthermore, generalized anxiety disorder (GAD) impacted around 6.8 million adults, or 3.1% of the U.S. population, underscoring the widespread burden of anxiety-related conditions.
The increasing incidence of such neurological and psychiatric disorders necessitates fast-acting, non-invasive treatment options, for which intranasal drug delivery offers a highly effective solution.
According to the Asthma and Allergy Foundation of America (2023), more than 27 million people in the United States were living with asthma in 2022, accounting for approximately 1 in every 12 individuals. Additionally, over 2 million adults aged 18 or older were affected by asthma. Data from the Allergy & Asthma Network (2023), further supported this, indicating that more than 26 million people, including 7% of adults and 6.5% of children, were living with asthma across the country.
Similarly, according to the Centers for Disease Control and Prevention (CDC, 2024), an estimated 16 million Americans have been diagnosed with chronic obstructive pulmonary disease (COPD). The data from the American Lung Association (2023), reported that 1.7 million individuals were diagnosed with COPD and other respiratory diseases, representing 4.6% of the U.S. population. The growing prevalence of asthma, COPD, and related respiratory conditions has led to a surging demand for intranasal drug delivery, which provides effective symptom relief and helps control disease progression.
The rising prevalence of asthma and chronic obstructive pulmonary disease (COPD) is driving growth in the intranasal drug delivery market in the region, as patients seek fast-acting, non-invasive therapies to manage respiratory symptoms like nasal congestion and airway inflammation. Intranasal corticosteroids and decongestants provide targeted relief with fewer systemic side effects, enhancing patient compliance and treatment effectiveness.
In addition to disease prevalence, regulatory advancements and product innovations are further fueling market growth. For instance, in September 2024, AstraZeneca announced that FluMist(R), the only self-administered influenza vaccine, was approved in the U.S. This needle-free nasal spray can be self-administered by adults up to 49 years old or administered by a caregiver to individuals aged 2-17, marking a major step forward in patient-friendly vaccine delivery.
Intranasal Drug Delivery Market Key Players:
Some of the key market players operating in the intranasal drug delivery market include Pfizer Inc., Johnson & Johnson Services, Inc., EMERGENT, UCB S.A., GSK plc, Amphastar Pharmaceuticals, Inc., Neurelis, Inc., Hikma Pharmaceuticals PLC, Perrigo Company, ARS Pharmaceuticals Operations, Inc., AstraZeneca, Therakind, AFT Pharmaceuticals, Teva Pharmaceutical Industries Ltd., Currax Pharmaceuticals LLC, Impel Pharmaceuticals LLC, Endo, Inc., Procter & Gamble, Teleflex Incorporated, Viatris, Inc., Amneal Pharmaceuticals LLC, and others.
Recent Developmental Activities in the Intranasal Drug Delivery Market:
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