首页 > 市场调查报告书 > 医疗设备

生技设备

市场调查报告书

商品编码

1345372

全球组织工程市场 - 2023-2030

Global Tissue Engineering Market - 2023-2030

出版日期: 2023年09月06日 | 出版商:

DataM Intelligence | 英文 195 Pages | 商品交期: 约2个工作天内

价格

※ 本网页内容可能与最新版本有所差异。详细情况请与我们联繫。

简介目录

市场概况

2022年全球组织工程市场规模预计为12亿美元，预计到2030年将达到17亿美元，2023-2030年预测期间复合年增长率为4.8%。由于 3D 生物打印技术具有根据患者特定组织和器官创建复杂组织结构的精确潜力，因此向 3D 生物打印技术的转变等趋势预计将主导全球组织工程市场。

全球组织工程市场近年来显着增长，预计将继续呈上升趋势。受干细胞治疗、器官芯片技术、基因编辑和 CRISPR 技术等显着潜力的影响，市场正在经历一个转型期。

此外，神经系统疾病、心血管和骨科疾病的患病率不断上升、3D生物打印和干细胞疗法等技术进步、人口老龄化加剧、道路事故和创伤相关损伤病例不断增加对骨植入物的需求不断增长，这些都推动了组织工程的发展市场规模。

使用组织工程方法治疗疾病的研究活动不断增长，以及成熟的生物製药和製药公司的存在，是北美地区需求的一些因素，这些地区的重要竞争对手包括Zimmer Biomet、Stryker Corporation、CollPlant Biotechnologies Ltd. 和其他在该地区积极运营的公司。市场。

市场动态

器官移植需求的不断增长推动组织工程市场的增长

器官移植需求的不断增长正在推动组织工程市场的发展。器官捐献者短缺问题日益严重，已成为医疗保健领域的一个重大问题。例如，根据卫生资源和服务管理局 2023 年的统计数据，全国移植等待名单上约有 104,234 人。每天都有超过 17 人在等待器官移植期间死亡。此外，每10分钟就有报导称需要进行器官移植。此外，随着这些数字的增加，由于器官捐献者稀缺，器官供应变得越来越困难。

因此，组织工程可以通过协助人体组织工程来替代受损的组织和器官，在解决器官捐献者稀缺问题上发挥重要作用。组织工程师通过结合生物材料、细胞和生物活性化学物质来开发可轻鬆融入人体的功能组织。皮肤、血管、膀胱、心臟和其他类型的组织已经被组织工程化并用于治疗人类疾病。由于上述所有因素，预计市场在预测期内将会增长。

不断增长的技术进步和合作将推动组织工程市场的增长

通过与不同领域的市场领导者合作，组织工程技术不断进步，预计将推动市场需求。例如，根据ISS国家实验室2023文章，维克森林再生医学研究所与RegenMed开发组织合作，旨在利用国际空间站（ISS）国家实验室的微重力条件发射生物工程肝臟和肾臟通过Axiom Space 的Ax- 2 任务将建筑物送入太空。研究人员希望通过研究微重力如何改变这些组织的血管化来改变器官移植和疾病模型。

因为，与传统的组织工程不同，微重力条件可以实现无支架组织的发育，从而有可能简化和改进整个过程。因此，该项目的成功可以显着减少器官移植等候名单，推进治疗测试的疾病模型，并为创新细胞疗法提供资源，揭示发展潜在的合作和进步如何推动组织工程领域的变革性进展。

慢性病患病率上升将推动组织工程市场增长

全球慢性疾病的日益流行预计将推动对有效组织工程技术的需求。例如，根据世界卫生组织2022年报告，慢性病是遗传、生理、环境和行为因素的综合作用。每年约有 410 亿人死于这些疾病，占全球总死亡人数的 74%。每年因心血管疾病死亡的人数最多，达 179 亿人，其次是癌症。

此外，随着癌症发病率的上升，需要3D生物打印等有效技术来对抗不断生长的癌细胞。例如，2023年EurekAlert组织发表的一篇文章中，韩国机械材料研究所（KIMM）开发出了世界上第一个3D生物打印技术，将增强NK免疫细胞的功能。这项新技术有望提高癌症治疗的有效性。因此，由于上述因素，预计市场在预测期内将受到推动，

组织工程技术相关的高成本将阻碍市场的增长

由于实验室或设施的初始投资、经常性费用以及移植本身的成本等多种因素，与组织工程技术相关的高成本是该市场的一个关键限制。以组织工程策略为例，实验室成本为 50,700 美元。相比之下，采购组织程序的设施投资成本为 168,750 美元。组织工程结构的製造成本也可能很高。

此外，细胞和组织捐赠计划的短缺可能导致组织工程的高成本。对私人和政府资金的需求、过度的医疗保健支出以及使用组织工程策略治疗糖尿病足溃疡的高额费用都可能导致组织工程的高成本。由于上述问题，预计组织工程市场在预测期内将受到重大限制。

Market Overview

Global Tissue Engineering Market size is valued at USD 1.2 billion in 2022, it is expected to reach USD 1.7 billion by 2030, with growth at a CAGR of 4.8% over the forecast period 2023-2030. The trend such as the shift towards 3D bioprinting technology due to its precise potential to create intricate tissue structures according to patient-specific tissues and organs is expected to dominate the global tissue engineering market.

The global tissue engineering market has grown significantly in recent years and is projected to continue on its upward trend. The market is undergoing a transformational period, influenced by several significant trends such as remarkable potential shown by stem cell therapy, organ-on-chip technology, and gene editing and CRISPR technology.

Furthermore, the rising prevalence of neurological disorder, cardiovascular and orthopedic disorders, technological advancements such 3D bioprinting and stem cell therapies, increasing aging population, growing demand for bone implants due to the increasing road accident and trauma related injury cases are driving up the tissue engineering market size.

The growing research activities for treating disease using tissue engineering approach and presence of establish biopharmaceutical and pharmaceutical companies are some of the factors in demand from North American regions with significant competitors like Zimmer Biomet, Stryker Corporation, CollPlant Biotechnologies Ltd., and others actively operating in the market.

Market Dynamics

The Increasing Demand for Organ Transplant to Drive the Growth of the Tissue Engineering Market

The increasing need for organ transplants is propelling the tissue engineering market. The shortage of organ donors is escalating and has become a significant issue in the healthcare sector. For instance, according to Health Resources and Services Administration 2023 statistics around 104,234 individuals are on the national transplant waiting list. Every day, over 17 individuals die while waiting for organ transplants. Furthermore, every 10 minutes, it is reported that an organ transplant is required. In addition, as these numbers rise, it is becoming increasingly difficult to supply organs due to a scarcity of organ donors.

Tissue engineering can thus play a significant part in addressing the scarcity of organ donors by assisting in the engineering of human tissue that will replace damaged tissues and organs. Tissue engineers develop functional tissues that integrate easily into the body by combining biomaterials, cells, and bioactive chemicals. Skin, blood vessels, bladders, hearts, and other types of these tissues have already been tissue engineered and employed in the therapy of human disease. As a result of all of the above, the market is expected to grow during the forecast period.

Growing Technological Advancements and Collaborations will Drive the Tissue Engineering Market Growth

The growing technological advancement in tissue engineering techniques by collarating with different field market leaders is expected to drive the demand for the market. For instance, according to ISS National Laboratory 2023 article, the collaboration between the Wake Forest Institute for Regenerative Medicine and the RegenMed Development Organization, it aims to use the microgravity conditions of the International Space Station (ISS) National Laboratory to launch bioengineered liver and kidney constructions into space via Axiom Space's Ax-2 mission. The Researchers want to transform organ transplantation and disease modeling by studying how microgravity alters the vascularization of these tissues.

Because, unlike traditional tissue engineering, microgravity conditions enable scaffold-free tissue development, potentially simplifying and improving the entire process. Thus, success in this project could significantly reduce organ transplant waitlists, advance disease modeling for therapy testing, and provide resources for innovative cell therapies, revealing how developing potential collaborations and advancements can drive transformative progress in the tissue engineering field.

Rising Prevalence of Chronic Disease will Drive the Tissue Engineering Market Growth

The growing prevalence of chronic disease across the globe is expected to drive the demand for effective tissue engineering techniques. For instance, according to World Health Organization report of 2022, chronic disease is a combination of genetic, physiological, environmental and behavioural factors. Every year approximately 41 Billion people die due to these disease that accounts 74% of total deaths globally. Patients suffering from cardiovascular disease accounts highest number of 17.9 billion deaths every year followed by cancer.

Furthermore, as the prevalence of cancer is rising, there is need of effective technology such as 3D bioprinting to combact with growing cancer cells. For instance, an article published by EurekAlert organization in 2023, Korea Institute of Machinery and Materials (KIMM) has developed the world's first 3D bioprinting technology that will enhance the functioning of NK immune cells. This New technology expected to improve effectiveness of cancer treatment. Thus, owing to the above factors the market is expected to drive over the forecast period,

High Cost Associated with the Tissue Engineering Technique Will Hamper the Growth of the Market

The high cost associated with the tissue engineering technique is a critical limitation for this market due to several factors, such as the initial investment for the laboratory or facility, recurrent fees, and the cost of the transplant itself. In the tissue engineering strategy, for example, the laboratory costs $50,700. In comparison, the facility investment cost for the procured-tissue procedure was US$168,750. Manufacturing costs for tissue-engineered structures can also be costly.

Additionally, the shortage of cell and tissue donation programs may contribute to tissue engineering's high cost. The demand for private and government funding, excessive healthcare spending, and the high expense of treating diabetic foot ulcers using a tissue engineering strategy may all contribute to the high cost of tissue engineering. As a result of the issues mentioned above, the tissue engineering market is expected to experience significant restraints over the forecast period.

Segment Analysis

The global tissue engineering market is segmented based on material type, application, end user and region.

Owing to the Growing Prevalence of Bone Disorders, the Orthopedics Segment Accounted for Approximately 43.2% of the Tissue Engineering Market Share

The orthopedics segment is poised to dominate the tissue engineering market due to growing focus on applying tissue engineering techniques to address orthopedic challenges. This segment is expected to grow owing to the factors such as rising prevalence bone and joint injuries, degenerative conditions, and musculoskeletal disorders, increasing aging population, and growing technological advancements.

For instance, according to the World Health Organization 2022 report, approximately 1.71 billion people are suffering from musculoskeletal conditions globally. This has led to leading causes of disability worldwide, among which low back pain has been the major cause of disability in more than 160 countries. Tissue engineering plays an important role by offering innovative solutions to repair and regenerate damaged bone and cartilage tissues.

Moreover, many companies are utilizing technological advancements such as 3D bioprinting using tissue engineering. For instance, Curiteva, the creator of the world's first 3D printed interbody spinal implants, has granted the medical device a restricted commercial distribution. For spine surgery, the Huntsville-based technology and manufacturing company uses 3D-printed spinal implants. Curiteva's recently FDA-approved Inspire platform is used to create the implants Thus, owing to the above factors the segment is expected to dominate over the forecast period.

Geographical Penetration

North America Accounted for Approximately 37.5% of the Market Share in 2022, Owing to the Rising Prevalence of Geriatric Population

North America, particularly the U.S., dominates the global tissue engineering market due to presence of huge number of key players settled in the region, technological advancements, and high research activities along with developments of 3D bioprinting, organ-on-chip, and stem cell technologies by major players in the area.

The demand for tissue engineering in the pharmaceutical industry is driven by an increase in the number of technologies and rising number of geriatric populations in the region. For instance, according to United States Census Bureau statistics, in U.S. 1 in 6 people are aging over 65. Moreover, in 2020 older population reached about 55.8 Billion or 16.8% of U.S. total population. Thus, tissue engineering will aid in restoring and improving the function of degenerated tissues, catering to the needs.

Moreover, the R&D process in this region is well established that creates opportunities for researcher to discover different technologies. For instance, in June 2023, Emulate, a company that creates in vitro drug research models, has introduced a new device dubbed Chip-A1. Chip-A1 is an extension of the company's Organ-on-a-Chip technology, which allows researchers to model human organs in vitro more accurately. The new chip improves in vitro modeling capabilities for cancer and cosmetics research, which require more precise models of human organs. The Chip-A1 technology is expected to find applications in cancer, cosmetics, and respiratory areas. Thus, owing to above factors the region is expected to grow over the forecast period.

Competitive Landscape

The major global players in the tissue engineering market include Zimmer Biomet, Stryker Corporation, 3D BioFibR Inc., Integra LifeSciences Corporation, CollPlant Biotechnologies Ltd., AbbVie (Allergan Aesthetics), Becton, Dickinson and Company, Athersys, Inc., BioTissue., Japan Tissue Engineering Co., Ltd, and among others.

COVID-19 Impact Analysis

The COVID-19 pandemic began in December 2019 with the SARS-CoV-2 virus in Wuhan, China, quickly spreading throughout the world, creating a significant impact on the tissue engineering market. The virus spreads easily by droplets from infected people, resulting in many illnesses. COVID-19 can cause major organ damage by affecting many organs. Tissue engineering approaches can be used to fix this, in which experts create novel ways to heal injured organs.

However, due to COVID-19, it has been difficult to obtain the materials needed for the present research. Shipping issues caused delays and cancellations of essential supplies, making it difficult for researchers and businesses to continue their work. Because of the pandemic, this condition hampered scientific development and had a significant impact on tissue engineering.

Russia-Ukraine War Impact Analysis

The Russia-Ukraine conflict has had a negative impact on the tissue engineering sector. The conflict has hampered the chances of global economic recovery, which has hampered the expansion of the tissue engineering sector. The conflict has also produced economic disruption, which has reduced demand for tissue engineering products. Thus, the conflict will create a major impact on the tissue engineering market over some period.

By Material Type

Synthetic Materials

Polymers

Hydrogels

Ceramics

Composites

Biologically Derived Materials

Extracellular Matrix (ECM) Proteins

Fibrin

Collagen

Silk

Others

By Application

Orthopedics
Musculoskeletal & Spine
Neurology
Cardiology
Skin & Integumentary
Others

By End-User

Hospitals
Academic and Research Institutes
Others

By Region

North America

U.S.

Canada

Mexico

Europe

Germany

U.K.

France

Spain

Italy

Rest of Europe

South America

Brazil

Argentina

Rest of South America

Asia-Pacific

China

India

Japan

Australia

Rest of Asia-Pacific

Middle East and Africa

Key Developments

On June 13, 2023, the Indian Drugs Controller has approved the first indigenously developed tissue engineering scaffold from mammalian organs by Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), an animal-derived Class D Biomedical Device that can rapidly heal skin wounds at low cost with minimal scarring.
On January 16, 2023, 3DBioFibR, a leading tissue engineering pioneer, announced the release of two new collagen fibre solutions, CollaFibR and CollaFibR 3D scaffold. These off-the-shelf solutions, created using 3D BioFibR's exclusive and revolutionary dry-spinning technology to generate collagen fibres at commercial scales, offer considerable advantages for tissue engineering and tissue culture applications and are now for sale.
On January 16, 2023, BioMed X, an independent German biomedical research institute, announced that its ongoing research collaboration with AbbVie has been extended. This marks the opening of the first BioMed X Institute in the United States, which will be in New Haven, Connecticut. The new US-based research cooperation will focus on immunology and tissue engineering, following a first cooperative research study on Alzheimer's disease at the BioMed X Institute in Heidelberg, Germany.

DMI Opinion

The global tissue engineering market is expected to grow more rapidly as a result of the shift toward 3D bioprinting technology for accurate tissue structure development, with trends such as stem cell therapy, organ-on-chip technology, and gene editing driving this expansion. Rising neurological, cardiovascular, and orthopedic illnesses, as well as technical advancements such as 3D bioprinting and stem cell therapies, an aging population, and an increased need for implants due to trauma cases, all contribute to the market's growth.

North America is seeing demand, led by big players, while the necessity for organ transplantation fuels growth. However, large expenses, an absence of contributors, and geopolitical tensions pose difficulties. The orthopedics market is thriving due to bone problems, but COVID-19 and geopolitical issues are hampering progress. Finally, the tissue engineering market is characterized by new trends and opportunities.

Why Purchase the Report?

To visualize the global tissue engineering market segmentation based on material type, application, end user, and region as well as understand key commercial assets and players.
Identify commercial opportunities by analyzing trends and co-development.
Excel data sheet with numerous data points of tissue engineering market-level with all segments.
PDF report consists of a comprehensive analysis after exhaustive qualitative interviews and an in-depth study.
Product mapping is available in excel consisting of key products of all the major players.

The global tissue engineering market report would provide approximately 53 tables, 54 figures and 195 Pages.

Target Audience 2023

Manufacturers/ Buyers
Industry Investors/Investment Bankers
Research Professionals
Emerging Companies

1. Methodology and Scope

1.1. Research Methodology
1.2. Research Objective and Scope of the Report

2. Definition and Overview

3. Executive Summary

3.1. Snippet by Material Type
3.2. Snippet by Application
3.3. Snippet by End User
3.4. Snippet by Region

4. Dynamics

4.1. Impacting Factors
- 4.1.1. Drivers
  - 4.1.1.1. The Increasing Demand for Organ Transplant
  - 4.1.1.2. The Growing Technological Advancements and Collaborations
- 4.1.2. Restraints
  - 4.1.2.1. The High Cost Associated with the Tissue Engineering Technique
- 4.1.3. Opportunity
  - 4.1.3.1. Increasing Demand for Personalized Medicine
- 4.1.4. Impact Analysis

5. Industry Analysis

5.1. Porter's 5 Forces Analysis
5.2. Supply Chain Analysis
5.3. Pricing Analysis
5.4. Regulatory Analysis

6. COVID-19 Analysis

6.1. Analysis of COVID-19
- 6.1.1. Scenario Before COVID-19
- 6.1.2. Scenario During COVID-19
- 6.1.3. Scenario Post COVID-19
6.2. Pricing Dynamics Amid COVID-19
6.3. Demand-Supply Spectrum
6.4. Government Initiatives Related to the Market During Pandemic
6.5. Manufacturers Strategic Initiatives
6.6. Conclusion

7. By Material Type

7.1. Introduction
- 7.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Material Type
- 7.1.2. Market Attractiveness Index, By Material Type
7.2. Synthetic Materials*
- 7.2.1. Introduction
- 7.2.2. Market Size Analysis and Y-o-Y Growth Analysis (%)
  - 7.2.2.1. Polymers
  - 7.2.2.2. Hydrogels
  - 7.2.2.3. Ceramics
  - 7.2.2.4. Composites
7.3. Biologically Derived Materials
7.4. Others

8. By Application

8.1. Introduction
- 8.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
- 8.1.2. Market Attractiveness Index, By Application
8.2. Orthopedics*
- 8.2.1. Introduction
- 8.2.2. Market Size Analysis and Y-o-Y Growth Analysis (%)
8.3. Musculoskeletal & Spine
8.4. Neurology
8.5. Cardiology
8.6. Skin & Integumentary
8.7. Others

9. By End User

9.1. Introduction
- 9.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
- 9.1.2. Market Attractiveness Index, By End User
9.2. Hospitals*
- 9.2.1. Introduction
- 9.2.2. Market Size Analysis and Y-o-Y Growth Analysis (%)
9.3. Hospitals
9.4. Academic and Research Institutes
9.5. Others

10. By Region

10.1. Introduction
- 10.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Region
- 10.1.2. Market Attractiveness Index, By Region
10.2. North America
- 10.2.1. Introduction
- 10.2.2. Key Region-Specific Dynamics
- 10.2.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Material Type
- 10.2.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
- 10.2.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
- 10.2.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
  - 10.2.6.1. U.S.
  - 10.2.6.2. Canada
  - 10.2.6.3. Mexico
10.3. Europe
- 10.3.1. Introduction
- 10.3.2. Key Region-Specific Dynamics
- 10.3.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Material Type
- 10.3.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
- 10.3.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
- 10.3.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
  - 10.3.6.1. Germany
  - 10.3.6.2. U.K.
  - 10.3.6.3. France
  - 10.3.6.4. Spain
  - 10.3.6.5. Italy
  - 10.3.6.6. Rest of Europe
10.4. South America
- 10.4.1. Introduction
- 10.4.2. Key Region-Specific Dynamics
- 10.4.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Material Type
- 10.4.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
- 10.4.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
- 10.4.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
  - 10.4.6.1. Brazil
  - 10.4.6.2. Argentina
  - 10.4.6.3. Rest of South America
10.5. Asia-Pacific
- 10.5.1. Introduction
- 10.5.2. Key Region-Specific Dynamics
- 10.5.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Material Type
- 10.5.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
- 10.5.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
- 10.5.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
  - 10.5.6.1. China
  - 10.5.6.2. India
  - 10.5.6.3. Japan
  - 10.5.6.4. Australia
  - 10.5.6.5. Rest of Asia-Pacific
10.6. Middle East and Africa
- 10.6.1. Introduction
- 10.6.2. Key Region-Specific Dynamics
- 10.6.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Material Type
- 10.6.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
- 10.6.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User

11. Competitive Landscape

11.1. Competitive Scenario
11.2. Market Positioning/Share Analysis
11.3. Mergers and Acquisitions Analysis

12. Company Profiles

12.1. Zimmer Biomet*
- 12.1.1. Company Overview
- 12.1.2. Product Portfolio and Description
- 12.1.3. Financial Overview
- 12.1.4. Key Developments
12.2. Stryker Corporation
12.3. 3D BioFibR Inc.
12.4. Integra LifeSciences Corporation
12.5. CollPlant Biotechnologies Ltd.
12.6. AbbVie (Allergan Aesthetics)
12.7. Becton, Dickinson and Company
12.8. Athersys, Inc.
12.9. BioTissue
12.10. Japan Tissue Engineering Co., Ltd.

LIST NOT EXHAUSTIVE