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全球介入神经放射学市场 - 2023-2030Global Interventional Neuroradiology Market - 2023-2030 |
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概述
全球介入神经放射学市场在 2022 年达到 19 亿美元,预计到 2030 年将达到 29 亿美元,2023-2030 年预测期间复合年增长率为 5.8%。
介入神经放射治疗是通过插入腹股沟区域的微导管来完成的,并在 X 射线引导下穿过通向大脑的血管。介入神经放射科医生目前采用微创手术来完成多种治疗,包括通过将血栓溶解药物直接输送到阻塞部位来治疗中风;动脉瘤治疗,将铂金弹簧圈插入动脉瘤隆起处,以防止血栓形成和破裂;以及通过向骨折的椎骨中註入水泥来加固骨骼的脊柱治疗。
介入神经放射学技术通常使我们能够进入手术难以到达的大脑和脊柱区域。由于手术是微创的,因此住院时间和康復期通常较短。在许多情况下,它们还降低了并发症和感染的风险
此外,全球介入神经放射学市场受到多种因素的推动,例如人口逐渐老龄化、对微创手术的需求不断增加以及脑动脉瘤患病率的上升。然而,栓塞线圈的高成本和熟练专业人员的缺乏是阻碍市场增长的主要因素。
动力学
脑动脉瘤患病率上升
脑动脉瘤患病率的上升是预测期内帮助市场增长的关键因素之一。例如,根据 NCBI 发表的一篇关于脑动脉瘤的文章,全球范围内脑动脉瘤的患病率约为 3.2%,平均年龄为 50 岁,总体性别比例为 1:1。这一比例在 50 岁后发生显着变化,女性比例不断增加,接近 2:1,这被认为是由于循环雌激素减少导致血管组织胶原蛋白含量减少。导致 SAH 的破裂率约为每 100,000 人中有 10 人发生。
在芬兰人和日本人等某些人群中这一比例更高。然而,这并不是因为这些人群中动脉瘤的患病率较高。动脉瘤性蛛网膜下腔出血的总死亡率被认为占全因死亡的 0.4% 至 0.6%,其中已知破裂的患者死亡率约为 20%,发病率高达 30% 至 40%。
技术进步的崛起
颠覆性技术将继续发展,并改变介入神经放射学工作的执行方式。提高治疗效果、缩短护理时间、降低成本并实现更好的以患者为中心的结果的改变是非常可取的。
其中一项技术是机器人辅助介入神经放射学,这是介入神经放射学和生物医学机器人学交叉的一个新兴领域。血管内机器人可以实现操作自动化,以减少手术时间并提高安全性,减少与电离辐射相关的职业危害,并扩大护理网络以缩小接受神经干预的地理差距。
大学健康网络的多伦多西部医院使用远程操作系统进行了首例人类机器人辅助神经介入手术。这项开创性的手术由 Vitor Mendes Pereira 博士领导,旨在改善中风治疗的可及性并降低动脉瘤破裂的风险。
该机器人系统是世界上唯一能够进行此类神经介入手术的系统。手术过程中,佩雷拉博士通过数字控制引导机械臂,以毫米级精度引导微导管穿过脑血管,并部署线圈,限制流向动脉瘤的血液。
放射科医生短缺
放射科医生的短缺是预测期内阻碍市场增长的关键因素之一。市场增长的下降将导致医疗机构犹豫是否投资用于介入神经放射学的昂贵设备。
放射科医生的短缺对患者的治疗结果产生了深远的影响。 “及时、准确的诊断在确定适当的治疗方案方面发挥着关键作用,尤其是在危重情况下。延迟或不准确的诊断可能会导致患者安全受损、住院时间延长和医疗费用增加。此外,我们有限的医疗资源也给我们带来了巨大的负担。”放射科工作人员可能会导致倦怠和疲劳,可能会影响报告的整体质量。
Global Interventional Neuroradiology Market reached US$ 1.9 billion in 2022 and is expected to reach US$ 2.9 billion by 2030, growing with a CAGR of 5.8% during the forecast period 2023-2030.
Interventional neuroradiology therapies are accomplished through microcatheters inserted in the groin area and, under X-ray guidance, threaded through the blood vessels leading into the brain. Interventional neuroradiologists currently employ minimally invasive procedures to accomplish a wide variety of treatments including stroke treatment by delivering clot-busting drugs directly to the site of the blockage; aneurysm therapy by inserting platinum coils into the aneurysm bulge to prevent clotting and rupture; and spinal treatments by injecting cement into a fractured vertebra to reinforce the bone.
Interventional neuroradiology techniques often allow us access to areas of the brain and spine that are surgically difficult to reach. Because the procedures are minimally invasive, hospital stays and recovery periods are normally shorter. In many cases, they also pose a lower risk for complications and infection
Furthermore, the global interventional neuroradiology market is driven by various factors like a progressively ageing population, increasing demand for minimally invasive procedures and a rise in the prevalence of the cerebral aneurysms. However, the high cost of embolization coils and the dearth of skilled professionals are the major factors hindering the market growth.
The rise in the prevalence of cerebral aneurysms is one of the key factors that helps the market to grow during the forecast period. For instance, according to an article published on cerebral aneurysms in NCBI, the worldwide prevalence of cerebral aneurysms is approximately 3.2%, with a mean age of 50 and an overall 1:1 gender ratio. This ratio changes significantly after age 50, with an increasing female predominance approaching 2:1, thought to be due to decreased circulating estrogen causing a reduction in the collagen content of the vascular tissue. The rate of rupture causing SAH is about 10 per 100,000.
This is higher in certain populations such as the Finnish and Japanese. However, this is not due to a higher prevalence of aneurysms in these populations. The overall mortality due to aneurysmal SAH is considered to be 0.4 to 0.6% of all-cause deaths, with an approximate 20% mortality and an additional 30 to 40% morbidity in patients with known rupture.
Disruptive technologies will continue to be developed and evolve the way interventional neuroradiology work is performed. Changes that improve treatment efficacy, shorten the duration of care, reduce costs and allow better patient-centred outcomes are highly desirable.
One of the technologies is Robotic-assisted interventional neuroradiology which is an emerging field at the intersection of interventional neuroradiology and biomedical robotics. Endovascular robotics can automate manoeuvres to reduce procedure times and increase safety, reduce occupational hazards associated with ionizing radiations, and expand networks of care to reduce gaps in geographic access to neuro interventions.
The University Health Network's Toronto Western Hospital has performed the first-in-human robot-assisted neuro-interventional procedure using a remote operation system. This groundbreaking procedure, led by Dr. Vitor Mendes Pereira, aims to improve stroke treatment access and reduce the risk of aneurysm rupture.
The robotic system is the only one in the world capable of this type of neuro-interventional procedure. The procedure involved Dr Pereira leading the robotic arm through digital controls, guiding a microcatheter with millimetric precision through brain vessels and deploying a coil, limiting blood flow to the aneurysm.
A shortage of Radiologists is one of the key factors that hamper the market growth during the forecast period. The decline in market growth will result in healthcare facilities hesitating to invest in expensive devices that are used in interventional neuroradiology.
The shortage of radiologists has far-reaching consequences for patient outcomes. "Timely and accurate diagnoses play a pivotal role in determining the appropriate course of treatment, especially in critical conditions. Delayed or inaccurate diagnoses may lead to compromised patient safety, prolonged hospital stays, and increased healthcare costs. Furthermore, the immense burden on our limited radiology workforce can lead to burnout and fatigue, potentially compromising the overall quality of reporting.
The global interventional neuroradiology market is segmented based on device type, application, end-user and region.
The microcatheters segment from the device type segment accounted for 41.7% and it is expected to be dominated during the forecast period. Microcatheters are small in size which helps to reduce the risk of vessel injury during the catheterization which helps the procedure to be processed safely during the timeline.
Microcatheters are soft and floppy as they are designed to be the least traumatic. Once a stable position is achieved with a guide catheter or distal access catheter, microcatheters are then advanced to the exact site in the cerebral vasculature. They have different lengths, diameters, stiffness, tractability, and radio-opaque markers, and some of them are even detachable for use in vascular malformations.
For instance, in March 2022 Guerbet announced it will more than double its line of microcatheters and launch a new line of guidewires, resulting in a broad range of interventional imaging and embolization solutions becoming available.
The company obtained its original offering of 18 references of SeQure and DraKon microcatheters as part of its acquisition of Accurate Medical Therapeutics in 2018. It received the CE mark in April 2019 and was US Food and Drug Administration (FDA) in 2018. Guerbet now expands the portfolio, adding 20 versions for a total of 38, and launching a new line of Axessio guidewires with two diameters.
North America is estimated to hold about 38.4 % of the total market share throughout the forecast period, owing to factors like new device launches by key players, strategic partnerships within the companies, Heavy utilization of medical imaging technologies, advanced healthcare infrastructure, regulatory framework, patient awareness, market competitiveness will drive the region to be largest during the forecast period.
For instance, in February 2023 RAYUS Radiology, a leading national provider of advanced diagnostic and interventional medical imaging services, announced the renewal of its partnerships with US Ski & Snowboard, US Speedskating and USA Bobsled/Skeleton and will continue to serve as an official Medical Provider for all three organizations and the elite athletes they represent.
The major global players in the market include: Balt Extrusion, Merit Medical Systems, Terumo Corporation, Medtronic, Penumbra, Inc., Mediterra, Stryker, Boston Scientific Corporation, Micro Port Scientific Corporation, MicroVention Inc. and others.
The COVID-19 pandemic has disrupted healthcare on an unprecedented scale. Covid had a minimal impact on the global neuroradiology market where neuro interventions were among the least affected, as most of these procedures fall under emergencies such as stroke, SAH, and intracerebral haemorrhage. neurointerventional procedures such as stroke thrombectomy and endovascular therapy for ruptured aneurysms increased marginally.
Moreover, Difficulties in providing essential/post-sales assistance due to lockdowns have degraded interventional neuroradiology products to end-users. Thus, the pandemic is not expected to have long-term effects on the primary growth drivers or end-users in the interventional neuroradiology market.
The global interventional neuroradiology market report would provide approximately 61 tables, 58 figures and 186 Pages.
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