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市场调查报告书
商品编码
1712541
全球胃癌治疗市场 - 2025-2033Global Gastric Cancer Treatment Market - 2025-2033 |
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2024年全球胃癌治疗市场规模达58.2亿美元,预计2033年将达到146.6亿美元,2025-2033年预测期内的复合年增长率为10.9%。
胃癌,也称为胃癌,是指始于胃内壁细胞的一种癌症。它是世界上最常见和最致命的癌症之一,在东亚、欧洲和南美洲部分地区尤其常见。胃癌可以在胃的任何部位发展,并可能扩散到其他器官,如食道、胰臟、肝臟和淋巴结。
胃癌主要起源于胃壁上皮细胞,导致腺癌,这是最常见的胃癌类型(约占 90-95% 的病例)。然而,胃癌也包括其他较为罕见的形式,如淋巴瘤(淋巴组织癌)、胃肠道间质瘤(GIST)和神经内分泌肿瘤。
驾驶员和约束装置
标靶治疗的不断进步显着推动了胃癌治疗市场的成长
胃癌治疗中最显着的进步之一是 HER2 标靶疗法的开发。 HER2(人类表皮生长因子受体 2)是一种在某些胃癌细胞中过度表现的蛋白质,导致细胞生长不受控制。曲妥珠单抗(赫赛汀)是一种针对 HER2 的单株抗体,是 HER2 阳性胃癌的突破性治疗方法。这种治疗方法的成功使得它与化疗联合治疗晚期胃癌被广泛使用。
例如,2024年10月,安斯泰来製药公司宣布,美国食品药品监督管理局(FDA)批准VYLOY(zolbetuximab-clzb)联合含氟嘧啶和铂类化疗,用于一线治疗局部晚期不可切除或转移性人表皮生长因子受体2(HER2)阴性胃腺癌或胃食管连接部(CLGEFDA)检测VYLOY 是美国首个也是唯一一个核准的 CLDN18.2 标靶疗法
标靶治疗的不断进步成为胃癌治疗市场成长的重要动力。朝向更个人化和有效的治疗转变,加上 FDA 对新药的批准、不断增长的市场接受度以及患者存活率的提高,都促进了这一增长。随着该领域研究的不断深入,预计标靶治疗将更加精细化,为胃癌患者带来更大的希望,市场规模也将进一步扩大。
与治疗相关的副作用和安全问题阻碍了市场的成长
儘管胃癌治疗取得了重大进展,但副作用和安全问题仍然是疾病管理的重大挑战。传统疗法和标靶疗法的不良反应常常使患者不愿遵守规定的治疗方案,影响他们的生活质量,并使治疗方案复杂化。这些担忧反过来又阻碍了胃癌治疗市场的广泛应用和成长。
化疗仍然是胃癌治疗的基石,但它会带来一系列严重的副作用。这些可能导致剂量减少、治疗停止和生活品质下降,最终阻碍市场成长。虽然标靶治疗和免疫疗法彻底改变了胃癌治疗,但这些疗法并非没有风险。儘管它们的副作用往往比化疗少,但它们仍然可能导致严重的免疫相关不良事件(irAE)或脱靶效应。
流行病学分析
胃癌的发生率呈上升趋势。根据DataM情报估计,2024年全球患病人数预计将接近102万,其中亚太地区患病人数最多,达1.9028亿。透过筛检进行早期发现、更好的治疗选择以及改善的公共卫生措施促使已开发国家的发病率和死亡率下降。然而,胃癌仍然是一个沉重的医疗负担,特别是在发展中国家和高风险族群。
The global gastric cancer treatment market size reached US$ 5.82 billion in 2024 and is expected to reach US$ 14.66 billion by 2033, growing at a CAGR of 10.9% during the forecast period 2025-2033.
Gastric cancer, also known as stomach cancer, refers to a type of cancer that begins in the cells lining the stomach. It is one of the most common and deadly forms of cancer worldwide, particularly prevalent in East Asia, Europe, and parts of South America. Gastric cancer can develop in any part of the stomach and may spread to other organs, such as the esophagus, pancreas, liver, and lymph nodes.
Gastric cancer primarily originates from the epithelial cells that line the stomach, leading to adenocarcinoma, which is the most common type of gastric cancer (around 90-95% of cases). However, gastric cancer can also include other, rarer forms such as lymphoma (cancer of lymphatic tissue), gastrointestinal stromal tumors (GISTs), and neuroendocrine tumors.
Market Dynamics: Drivers & Restraints
Rising advancements in targeted therapies are significantly driving the gastric cancer treatment market growth
One of the most notable advancements in gastric cancer treatment has been the development of HER2-targeted therapies. HER2 (human epidermal growth factor receptor 2) is a protein overexpressed in some gastric cancer cells, leading to uncontrolled cell growth. Trastuzumab (Herceptin), a monoclonal antibody targeting HER2, has been a groundbreaking treatment for HER2-positive gastric cancer. The success of this treatment has led to its widespread use in combination with chemotherapy for advanced gastric cancer.
For instance, in October 2024, Astellas Pharma Inc. announced that the U.S. Food and Drug Administration (FDA) approved VYLOY (zolbetuximab-clzb) in combination with fluoropyrimidine- and platinum-containing chemotherapy for the first-line treatment of adults with locally advanced unresectable or metastatic human epidermal growth factor receptor 2 (HER2)-negative gastric or gastroesophageal junction (GEJ) adenocarcinoma whose tumors are claudin (CLDN) 18.2 positive as determined by an FDA-approved test. VYLOY is the first and only CLDN18.2-targeted therapy approved in the U.S.
The rising advancements in targeted therapies have been a significant driver for the growth of the gastric cancer treatment market. The shift towards more personalized and effective treatments, combined with the FDA approvals of new drugs, the growing market acceptance, and the increased survival rates in patients, all contribute to this growth. As the research in this field continues to progress, it is expected that targeted therapies will become even more refined, offering greater hope for gastric cancer patients and expanding the market further.
Side effects and safety concerns associated with the treatment are hampering the market growth
Despite the significant advancements in gastric cancer treatment, side effects and safety concerns continue to pose major challenges in the management of the disease. The adverse effects associated with both traditional and targeted therapies often deter patients from adhering to prescribed regimens, impact their quality of life, and complicate treatment regimens. These concerns, in turn, hinder the widespread adoption and growth of the gastric cancer treatment market.
Chemotherapy remains a cornerstone of treatment for gastric cancer, but it is associated with a range of severe side effects. These can lead to dose reductions, discontinuation of therapy, and decreased quality of life, which ultimately hampers market growth. While targeted therapies and immunotherapies have revolutionized gastric cancer treatment, these therapies are not without their risks. Although they tend to have fewer side effects than chemotherapy, they can still cause severe immune-related adverse events (irAEs) or off-target effects.
Epidemiology Analysis
The incidence of gastric cancer is rising. As per DataM intelligence estimates, nearly 1.02 million prevalent cases are estimated worldwide in 2024. The region with the highest prevalence is the Asia-Pacific, accounting for 190.28 million cases. Early detection through screening, better treatment options, and improved public health measures have contributed to the decline in incidence and mortality rates in developed countries. However, gastric cancer continues to present a major healthcare burden, particularly in developing nations and among high-risk populations.
The global gastric cancer treatment market is segmented based on cancer type, treatment type, route of administration, and region.
The chemotherapy segment is expected to dominate the gastric cancer treatment market with the highest market share
Chemotherapy is frequently used as the primary treatment in advanced gastric cancer, often in combination with targeted therapies or immunotherapy. In cases where surgery is not possible, chemotherapy serves as a crucial palliative treatment to control symptoms, slow the disease's progression, and improve survival rates. For instance, FOLFOX (a combination of 5-fluorouracil (5-FU), oxaliplatin, and leucovorin) is a standard chemotherapy regimen used in gastric cancer. This regimen is particularly effective for advanced gastric cancer and has been widely adopted.
Chemotherapy is frequently combined with targeted therapies like trastuzumab, ramucirumab, and nivolumab to enhance efficacy, especially in advanced or metastatic gastric cancer. These combination regimens have become the standard of care in many treatment protocols. The growing trend of combining chemotherapy with newer therapies has expanded its market dominance, as it remains the central component of first-line and second-line treatment regimens in both HER2-positive and HER2-negative gastric cancers.
North America is expected to hold a significant position in the global gastric cancer treatment market with the highest market share
The FDA (U.S. Food and Drug Administration) and Health Canada are at the forefront of regulatory approvals for new cancer therapies, including those for gastric cancer. These agencies have fast-tracked and drug approvals for novel treatments like TEVIMBRA (tislelizumab-jsgr), nivolumab (Opdivo), trastuzumab (Herceptin), and ramucirumab (Cyramza). This further accelerates the market growth in the region with various effective treatments.
For instance, in December 2024, BeiGene, Ltd., a global oncology company that intends to change its name to BeOne Medicines Ltd., announced the U.S. Food and Drug Administration (FDA) approved TEVIMBRA (tislelizumab-jsgr), in combination with platinum and fluoropyrimidine-based chemotherapy, for the first-line treatment of unresectable or metastatic HER2-negative gastric or gastroesophageal junction adenocarcinoma (G/GEJ) in adults whose tumors express PD-L1 (>=1).
North America has been a leader in adopting targeted therapies and immunotherapies, which are increasingly used to treat gastric cancer. The region's healthcare system supports the use of expensive, but highly effective, biologics and immunotherapy drugs that target specific proteins or immune checkpoints involved in cancer progression. For instance, Trastuzumab (Herceptin) is widely used for HER2-positive gastric cancer, and its combination with chemotherapy has led to better survival rates. Nivolumab (Opdivo), an immune checkpoint inhibitor, is also approved for use in gastric cancer and has been shown to significantly improve survival in combination with chemotherapy.
Top companies in the gastric cancer treatment market include Merck & Co., Inc., Eli Lilly and Company, Genentech USA, Inc., Pfizer Inc., Astellas Pharma Inc., Bristol-Myers Squibb Company, Blueprint Medicines Corporation, Daiichi Sankyo, Inc., BeiGene, Ltd., Ipsen Biopharmaceuticals Inc., Taiho Oncology, Inc., and Deciphera Pharmaceuticals, LLC., and among others.
The global gastric cancer treatment market report delivers a detailed analysis with 68 key tables, more than 61 visually impactful figures and 198 pages of expert insights, providing a complete view of the market landscape.
Target Audience 2024
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