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市场调查报告书
商品编码
1322942
全球抗体药物偶联物 (ADC) 增长机会,预测至 2028 年Global Antibody Drug Conjugate (ADC) Growth Opportunities, Forecast to 2028 |
与创新平台开发商的合作推动增长潜力
该研究服务提供了全球 ADC 市场的概况,并提供了从 2023 年到 2028 年的六年收入预测。 ADC 由多个组件结构,例如抗体、缀合化学、连接子和有效负载。市场竞争非常激烈,许多公司致力于每个结构要素,而其他公司则仅开发 ADC。超越标准抗体的靶向递送载体的开发正在提高这些药物的效力并开闢新的癌症治疗可能性。新技术旨在解决现有 ADC 技术的缺点,包括稳定性低、耐受性差、疗效低、治疗指数窄以及 ADC 製造方面的挑战。
根据 Frost & Sullivan 的分析,依赖委外研发机构(CDMO)/合同委外研发机构(CRO) 进行早期药物开发的中小企业正在创造新型抗体治疗技术。许多抗体开发商正在减少内部研发工作,并增加抗体治疗产品线的许可和收购,以加强其管道。所有主要 CDMO 都在进行新投资以支持下一代 ADC,从而使该细分市场更具竞争力。生物製药公司正在转向 ADC,以从选择性肿瘤抗原的靶点特异性中获益。 ADC 在过去两年中已获得七项批准,反映出开发人员使用稳健的方法来提高有效负载效力的成功率。
Collaborations with Innovative Platform Developers will Drive Growth Potential
This research service overviews the global ADC market and provides a 6-year revenue forecast from 2023 to 2028. An ADC comprises multiple components such as the antibody, conjugation chemistry, linker, and payload. Many companies are working on each component while others only develop ADCs, which makes the market highly competitive. The development of targeted delivery vehicles over standard antibodies is improving the performance of these drugs and expanding their potential for treating new cancers. New technologies are trying to address drawbacks of existing ADC technology, such as poor stability, leading to poor tolerability, efficacy, and a narrow therapeutic index and challenging ADC manufacturing.
Frost & Sullivan's analysis shows that small and mid-sized enterprises that rely on contract development and manufacturing organizations (CDMOs)/contract research organizations (CROs) for initial drug development create novel antibody therapeutic technologies. Many antibody developers have been decreasing in-house R&D efforts and increasing in-licensing or acquiring therapeutic antibody product lines to strengthen their pipelines. All major CDMOs are stepping up with new investments to support the next generation of ADC, making the segment more competitive. Biopharmaceutical companies are focusing on ADCs to reap the benefits of target specificity for selective tumor antigens. Developers are using robust approaches to improve payloads' potency as ADCs reflect the success rate in the last two years with seven approvals.