次世代定序仪(NGS) 和基因组分析的进展

Advancements in Next-gen Sequencing and Genomic Analysis

出版日期: 2023年12月07日 | 出版商:

Frost & Sullivan | 英文 67 Pages | 商品交期: 最快1-2个工作天内

价格

简介目录

NGS 平台和基因组分析确保精准医学的变革性成长

定序技术多年来不断发展，能够充分利用人类基因组的价值，并深入了解 DNA 和 RNA 序列，从而提供丰富的人类生物学知识。从Sanger测序到新一代定序，技术和化学方法不断改进和发展，以降低成本并加快进度。 NGS 正在被纳入基础生命科学研究中，以了解疾病生物学以进行药物研发和诊断。

NGS化学的发展，包括单分子实时测序、合成测序、奈米孔测序以及离子和半导体技术，以及测序设备的小型化和NGS的自动化，正在推动NGS在生物实验室的采用。。全基因组定序、标靶定序、全EXOME定序和单细胞 RNA 定序均可精确定位和识别结构变异、SNP、遗传变异、病原体检测、患者分层、药物研发等。在体学。

NGS 市场目前正在见证新兴企业的崛起，这些企业提供改进的化学方法和设备来提供低成本的全基因组定序，从而提高全部区域的采用率并推动精准医疗。用于分析定序资料的人工智慧/机器学习平台的技术进步有助于在数小时内分析和解释大量定序资料。 NGS在资料主导的临床医学中发挥重要作用，并将继续改善全球医疗保健系统。该分析强调了 NGS 和基因组分析平台的发展，这些平台使全基因组定序更容易实现，并加速早期临床决策，以获得更好的健康结果。

定序方法的演变
导致先进定序技术改进的关键重点领域
NGS 的重要性和能力日益增强
技术干预提高C
NGS 从焦磷酸测序到高级 NGS 的演变
NGS定序化学及其采用
NGS 化学类型
业界领先的相关人员形势和 NGS 平台
市场领导正在进行的定序技术开拓
改善基因组结果的策略
新兴市场参与者专注于提高自动化、人工智慧整合和定序化学
使用 NGS 的准确快速的核酸定序方法
NGS 方法和基因组分析的趋势
机器人技术、液体处理和文库製备的进步推动了 NGS 自动化系统的发展
专注于 NGS 自动化的关键推动因素
人工智慧在促进基因组分析中的作用
专注于NGS分析的人工智慧和生物资讯学平台的主要企业
NGS测序供应商和整合服务的产业形势

应用

NGS 在各种应用中的采用不断增长
NGS 和基因组分析改进了疾病诊断的突变分析和生物标记发现
不断发展的 NGS 协作和技术平台，以开发基于 NGS 的快速诊断测试
NGS 和基因组分析改进了精准医疗的预测分析
专注于使用 NGS 进行精准医疗的主要企业
改进 NGS 和基因组分析
成长中的基于 NGS 的药物研发公司
次世代定序仪的未来

研发合作

扩大网路收购以提高 NGS 能力
全球公共资金和联盟努力促进技术知识和合作研究

成长机会宇宙

成长机会 1：经济实惠的定序服务
成长机会 1：经济实惠的定序服务
成长机会 2：低收入和中等收入国家的临床总体基因体学
成长机会3：平台安全与监管
成长机会3：平台安全与监管

附录

技术完备等级(TRL)：说明

下一步

简介目录

Product Code: DABB

NGS Platforms and Genomic Analysis to Ensure Transformational Growth of Precision Medicine

Sequencing technologies have evolved over the years to harness the value of the human genome and dive deep into DNA and RNA sequences which offer immense knowledge of human biology. From Sanger sequencing to next-generation sequencing, technologies and chemistries have improved/advanced to reduce costs and ensure faster timelines. NGS has integrated itself into basic life science research to understand disease biology for drug development and diagnostics.

Developments in NGS chemistries such as single-molecule real-time sequencing, sequencing by synthesis, nanopore sequencing, ion and semiconductor technology, in addition to miniaturization of sequencing instrumentation and automation of NGS, boost the adoption of NGS across biological labs. Whole genome sequencing, targeted sequencing, whole exome sequencing, whole transcriptome sequencing, and single-cell RNA sequencing have all found specific applications across omics where they accurately indicate and identify structural variants, SNPs, genetic variations, pathogen detection, patient stratification, drug discovery, and so on.

The NGS market is now witnessing a rise in emerging players that offer improved chemistries and instrumentation to deliver low-cost whole genome sequencing, increasing adoption across geographies and driving precision medicine. Technological advancement of AI-/ML-powered platforms for analyzing sequencing data is helping analyze and interpret large volumes of sequencing data within hours. NGS plays a key role in data-driven clinical medicine and will continue to improve the global healthcare system. The analytics covers developments in NGS and genomic analysis platforms that will make whole genome sequencing more accessible and accelerate early clinical decisions for better health outcomes.

Strategic Imperatives

Why Is It Increasingly Difficult to Grow?The Strategic Imperative 8™: Factors Creating Pressure on Growth
The Strategic Imperative 8™
The Impact of the Top 3 Strategic Imperatives on the Advances in Next-Generation Sequencing and Genomic Analysis Industry
Growth Opportunities Fuel the Growth Pipeline Engine™
Research Methodology

Growth Opportunity Analysis

Scope of Analysis
Growth Drivers
Growth Drivers Analysis
Growth Restraints
Growth Restraints Analysis
Key Findings
Global Trends In Next-gen Sequencing and Genomic Analysis

Technology Innovations and R&D Scenario in Next-generation Sequencing and Genomic Analysis

The Evolution of Sequencing Methods
Key Focus Areas Leading to Improvements in Advanced Sequencing Technologies
The Growing Significance of NGS and its Capabilities
Technology Intervention Improving C
Evolution of NGS from Pyrosequencing to Advanced NGS
NGS Sequencing Chemistries and Their Adoption
Types of NGS Chemistries
Leading Industry Stakeholder Landscape and the NGS Platforms
Ongoing Sequencing Technology Developments of Market Leaders
Strategies that Improve Genomic Outcomes
Emerging Market Players Focus on Automation, AI integration and Improving Sequencing Chemistries
Approaches for Accurate and Fast Nucleic Acid Sequencing Using NGS
Trends in NGS Approaches and Genome Analysis
Advances in Robotics, Liquid handling and Library Preparation Advance NGS Automation Systems
Key Enablers Focusing on Automation for NGS
Role of AI in Driving Genomic Analysis
Key Players Focusing On AI, Bioinformatics Platforms For NGS Analysis
Industry Landscape of NGS Sequencing Providers and Integrated Services

Applications

Growing Adoption of NGS in Various Applications
NGS and Genomic Analysis Improving Mutational Analysis and Biomarker Discovery for Disease Diagnosis
Growing NGS Collaboration and Technology Platforms to Develop Rapid-NGS-based Diagnostic Tests
NGS And Genomic Analysis Improving Predictive Analysis for Precision Medicine
Key Players Focusing on NGS driven Precision Medicine
NGS And Genomic Analysis Improving
Growing NGS - Based Drug Discovery Companies
The Road Ahead for Next-generation Sequencing

R&D Collaborations

A Growing Network Acquisition to Improve NGS Capabilities
Global Public Funding and Consortium Efforts to Encourage Technology Knowledge and Collaboration

Growth Opportunity Universe

Growth Opportunity 1: Affordable Sequencing Services
Growth Opportunity 1: Affordable Sequencing Services
Growth Opportunity 2: Clinical Metagenomics for Low- and Middle-income Countries
Growth Opportunity 3: Platform Security and Regulations
Growth Opportunity 3: Platform Security and Regulations