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市场调查报告书
商品编码
1811968
癌症免疫疗法市场成长机会(2024-2030)Growth Opportunities in the Immuno-oncology Therapeutics Market, 2024-2030 |
下一代免疫疗法、人工智慧和生物标誌物驱动的个人化治疗进步将推动转型成长
全球癌症发生率预计将从2022年的2,000万例增加77%,到2050年将超过3,500万例。饮酒、吸烟、肥胖和空气污染是导致癌症发生率上升的主要原因。现今的癌症研究重点是细胞和基因治疗、抗体药物复合体(ADC)、查核点抑制剂和多特异性抗体。临床试验主要集中于放射线治疗、化疗和多种免疫疗法药物的组合,目前有超过5000种癌症免疫疗法正在开发中。
免疫肿瘤学 (IO) 彻底改变了癌症治疗,但必须应对临床试验挑战,以改善患者预后并加快核准。许多免疫肿瘤学疗法在规模过大或患者群体不匹配的情况下进行评估,最终失败。人体免疫反应并非总是能够透过动物模型或二维体外系统预测。传统的随机对照试验无法检测出药物未达到预期疗效的征兆,也不需要持续调整药物。
人工智慧和生物标记指导的患者选择、抵消抗药性的联合疗法、免疫相关不利事件的即时安全监测、改善患者可及性的分散式临床试验以及自适应的人工智慧主导的试验设计是应对这些挑战的基本策略。这些方法使相关人员能够增强肿瘤免疫疗法创新,并提高癌症治疗的有效性、可近性和安全性。
改良的生物标记平台有助于提升我们对肿瘤免疫生物学认知的深度和精准度。生物标记研究的快速发展领域包括多重免疫组化 (IHC)、基于NGS的基因突变和表现图谱检测、高阶基因结构的表观遗传图谱绘製以及肿瘤能量状态的代谢谱分析。
本研究检视了临床和管道发展、技术创新和区域市场动态,以概述 2025 年至 2030 年全球 IO 市场和收益预测。地理覆盖范围包括北美、欧洲、亚太、中东和北非以及拉丁美洲。
本研究检验了推动免疫治疗发展的关键主题和技术,重点关注查核点抑制剂、抗体偶联药物 (ADC)、双特异性抗体、癌症疫苗以及过继性细胞疗法,包括 CAR-T、TCR 和 TIL。研究重点关注策略目标领域,包括克服对 PD-1/PD-L1 抑制剂的抗药性,以及下一代药物,包括同种异体疗法和特异性治疗方法。在这种动态环境中,本研究也探讨了成长驱动因素、阻碍因素以及相关人员的机会。
收益及预测
预计 2024 年营收将达到 1,106.9 亿美元,在 2021 年至 2030 年的研究期间内,年复合成长率(CAGR)为 10.7%。
三大战略要务对生医治疗产业的影响
压缩客户价值链
为什么
压迫免疫肿瘤学市场的价值链意味着优化和简化患者的诊疗过程,包括诊断、治疗和术后护理。这可以透过整合各种医疗服务并利用免疫肿瘤学临床试验市场的尖端技术来实现。
全面全面的癌症治疗非常重要,特别是在市场脉络,包括综合治疗设施、协调的护理团队和广泛的后续护理计划。
观点
免疫肿瘤学市场的公司正在提供直接面向消费者的服务,例如家用癌症风险基因检测套组,以加速诊断过程。
数位技术在自适应、人工智慧主导的癌症临床试验市场脉络优化营运、提高病人参与并客製化护理,包括远端咨询、数据驱动的诊断和治疗建议。
透过将种族、年龄和社会经济因素紧密结合到生存和临床决策中,肿瘤学价值链可以显着改善免疫肿瘤生物标记平台市场的患者体验。
颠覆性技术
为什么
最近的技术进步,包括单细胞定序和空间转录组学,大大增强了我们对肿瘤微环境免疫生物学的理解,影响了自适应人工智慧驱动的癌症临床试验市场。
一种新的人工智慧方法利用治疗变化预测来识别临床试验候选者,并推动了次世代定序仪(NGS) 数据在下一代免疫肿瘤学市场中用于患者试验匹配的应用。一种机器学习演算法利用患者报告的结果变数来预测急性癌症治疗的发生率。
赛诺菲正在与 Owkin 合作,以加强生物标记识别并提高临床试验的成功率,而葛兰素史克则与 Tempus 合作,以支持其在免疫肿瘤学市场的努力。
观点
多重模式方法增进了我们对与免疫肿瘤学市场相关的肿瘤-免疫系统交互作用的理解。数位化工具有助于组织数据、揭示复杂模式并灵活提取免疫学相关资讯。由于致力于免疫疗法创新的公司寥寥无几,因此选择至关重要。
人工智慧和加速运算正在彻底改变医疗保健,NVIDIA 等公司大力投资医疗保健服务,包括 IOVIA、Illumina 和 Mayo Clinic,影响着自适应人工智慧主导的癌症临床试验市场。
竞争激烈程度
为什么
免疫肿瘤学市场竞争激烈,多家公司追求类似的临床目标,大型製药公司与新兴生物技术公司合作,在免疫肿瘤学临床试验市场中寻求新资产。
随着免疫疗法、放射线治疗、标靶治疗和微生物组调节等新兴需求的融合,临床开发和法规环境变得更加复杂。
免疫肿瘤生物标记平台市场在细胞疗法、肿瘤病毒、mRNA 疫苗和人工智慧生物标记发现方面取得了进展,推动了许多策略合作伙伴关係、合资企业、合併和收购。
观点
儘管近年来取得了一些突破,但癌症免疫疗法领域在临床试验市场中仍面临诸多障碍,包括疗效有限、疗效持续时间短暂以及副作用意外等。一种常见的策略是专注于透过精准标靶药物应用于特定的患者群体和肿瘤类型,从而实现差异化。
影响因素:人类正在推动公司透过RWE优化其品牌扩大策略。市场RWE推动早期小细胞肺疾病的退出。
驱动程式
成长阻碍因素
Advances in Next-Generation Immunotherapies, AI, and Biomarker-Driven Personalization are Driving Transformational Growth
Worldwide cancer incidence is expected to exceed 35 million new cases by 2050, a 77% rise from the 20 million cases in 2022. Alcohol intake, tobacco usage, obesity, and air pollution are the main causes of this increase. Cancer studies today emphasize cell and gene therapy, antibody-drug conjugates (ADCs), checkpoint inhibitors, and multi-specific antibodies. With clinical trials emphasizing combinations of radiation, chemotherapy, or many immunotherapy medicines, more than 5,000 immuno-oncology medications are under development.
Although immuno-oncology (I-O) has revolutionized cancer therapy, problems with clinical trials must be resolved to improve patient outcomes and speed approvals. Many I-O therapies show failure when evaluated across too-large or incompatible patient groups; human immune responses cannot always be deduced from animal models and two-dimensional in vitro systems. Conventional randomized controlled studies may not find signs or call for continuous changes should a medicine not be functioning as expected.
AI and biomarker-based patient selection, combination approaches to offset resistance, real-time safety monitoring for immune-related adverse events, distributed clinical trials to improve patient access, and adaptive, AI-driven trial designs are fundamental strategies to meet these challenges. With these approaches, stakeholders are strengthening I-O innovation and improving the effectiveness, accessibility, and safety criteria of cancer therapy.
Improved biomarker platforms help to increase tumor immunobiology's depth of knowledge and accuracy. Fast-growing fields in biomarker research include multiplex IHC, NGS-based testing for gene mutations and expression profiles, epigenetic mapping for higher-order gene structures, and metabolic profiling for tumor energy status.
Frost & Sullivan studied clinical and pipeline developments, technological innovation, and regional market dynamics to develop this research service, which provides an overview of the global I-O market and a revenue projection from 2025 to 2030. The geographical scope is North America, Europe, Asia-Pacific, the Middle East and North Africa, and Latin America.
With an eye on checkpoint inhibitors, ADC, bispecific antibodies, cancer vaccines, and adoptive cell treatments including CAR-T, TCR, and TILs, this report examines the main themes and technologies driving the evolution of I-O therapies. Along with strategic target areas including overcoming resistance to PD-1/PD-L1 inhibitors, it stresses next-generation drugs including allogeneic approaches and multi-specific modalities. In this fast-changing environment, the study also investigates growth drivers, restraints, and opportunities for stakeholders.
Revenue Forecast
The revenue estimate for the base year 2024 is projected at $110.69 billion, with a compound annual growth rate (CAGR) of 10.7% during the study period from 2021 to 2030.
The Impact of the Top 3 Strategic Imperatives on the I-O Therapeutics Industry
Customer Value Chain Compression
Why
Patient value chain compression in the immuno-oncology market entails optimizing and simplifying the patient's journey, including the stages of diagnosis, treatment, and post-treatment care. This is accomplished by combining different healthcare services and using cutting-edge technology in immuno-oncology clinical trials market.
Comprehensive, integrated cancer care is important, especially in the context of the immuno-oncology biomarker platforms market. Integrated treatment facilities, coordinated care teams, and extensive aftercare plans are examples of this.
Frost Perspective
Companies in the immuno-oncology market are providing direct-to-consumer services, such as cancer risk genetic testing kits that may be used at home thus expedite the diagnosing process.
Digital technology optimizes operations, improves patient engagement, and customizes treatment in the context of the adaptive AI-driven oncology trials market. This includes remote consultations, data-driven diagnostics, and treatment recommendations.
By tightly integrating racial, age, and socioeconomic considerations into their survival and clinical decision-making, the oncology value chain can significantly improve patients' experiences within the immuno-oncology biomarker platforms market.
Disruptive Technologies
Why
Recent technological advancements, including single-cell sequencing and spatial transcriptomics, have greatly enhanced our understanding of the immunobiology of the tumor microenvironment, influencing the adaptive AI-driven oncology trials market.
A new AI method uses treatment change predictions to identify clinical trial candidates, advancing the use of next-generation sequencing (NGS) data for patients' trial matching in the next-generation immuno-oncology therapies market. A machine learning algorithm predicts cancer acute care occurrences using patient-reported outcome variables.
Sanofi is collaborating with Owkin to boost biomarker identification and raise clinical trial success rates. GSK has teamed with Tempus to aid the effort in the immuno-oncology market.
Frost Perspective
Multi-modality methods have improved our understanding of tumor-immune system interactions relevant to the immuno-oncology market. Digital tools help to organize data, uncover complicated patterns, and extract immunologically relevant information in a flexible way. Since few companies respond to innovations in immunotherapy, it is crucial to select.
AI and accelerated computing are revolutionizing medicine, and companies like NVIDIA are investing heavily in healthcare services, including IOVIA, Illumina, and Mayo Clinic, impacting the adaptive AI-driven oncology trials market.
Competitive Intensity
Why
The immuno-oncology market is competitive, with several companies aiming for similar clinical targets and big pharma teaming up with emerging biotech for novel assets in the immuno-oncology clinical trials market.
Clinical development and regulatory environments are complicated by the convergence of immunotherapy, radiation, targeted treatments, and new demands, such as microbiome regulation.
Cell treatments, oncologic viruses, mRNA vaccines, and AI-driven biomarker discovery are advancing in the immuno-oncology biomarker platforms market. These developments have driven many strategic alliances, joint ventures, mergers, and acquisitions.
Frost Perspective
Despite recent breakthroughs, there are still obstacles in the field of cancer immunotherapy within the immuno-oncology clinical trials market. These include limited effectiveness, temporary duration, and unintended impacts. Under a general strategy, differentiating via precision targets medicines for certain patient groups or tumor types has become a focal point.
Factors: Human beings are asking companies to optimize label expansion strategies via RWE. Market RWE will facilitate escape from earlier stages of the small cell lung.
Growth Drivers
Growth Restraints