超越 CRISPR：DNA 重写领域的最新技术进展

Beyond CRISPR: Recent Technology Advances in Rewriting DNA

出版日期: 2025年10月22日 | 出版商:

Frost & Sullivan | 英文 57 Pages | 商品交期: 最快1-2个工作天内

价格

简介目录

重塑基因编辑未来的新工具

本研究检验了CRISPR/Cas系统以外的新兴下一代基因编辑技术，重点在于先导编辑、碱基编辑、桥接RNA、SeekRNA和基因写入平台等进展。这些工具具有更强大的编辑能力、更低的脱靶效应和更高的精确度，使其在治疗方法开发、精准医疗和功能基因组学领域具有突破性意义。为了提高基因组编辑的精确度和效率，本研究着重介绍了人工智慧（AI）和机器学习在引导RNA优化、脱靶预测和可扩展临床应用方面的应用。透过分析包括学术联盟、大型製药企业、生物技术Start-Ups公司和提供AI驱动编辑解决方案的公司在内的关键相关人员，本研究展现了合作创新生态系统的全貌。此外，为了评估商业化准备情况，本研究检验了北美、欧洲、亚太地区和新兴地区的全球资金筹措趋势、投资模式和法规环境。透过识别成长前景和策略联盟，本研究揭示了颠覆性工具如何改变基因医学和生物技术的未来。

精准编辑－拓展基因编辑的精确性和多功能性
Prime Editing 的最新创新
桥接RNA—第三代基因工程
SeekRNA—一种精准基因编辑的新方法
表观基因编辑
碱基编辑：实现单核苷酸精确度
低音编辑领域的最新创新
基因编写—基因组工程的新蓝图
基因写作领域的最新进展

人工智慧和机器学习在基因编辑的应用

人工智慧与机器学习：人工智慧/机器学习在基因编辑的应用
基因编辑和人工智慧领域的新兴趋势

推进基因编辑技术向临床应用：相关人员和解决方案

参与基因编辑技术开发的相关人员

资金筹措和合作趋势

2023-2025年全球关键基因编辑合作项目
产业资金筹措概况 - 全球 2023-2025 年
学术资金筹措概况 - 全球 2023-2025 年
基因编辑的区域趋势：进展与应用

成长机会领域－超越 CRISPR 的 DNA 基因编辑

成长机会 1：人工智慧驱动的基因编辑中的指导序列设计与脱靶预测
成长机会2：下一代基因编辑工具
成长机会 3：大规模 DNA 整合与重写

附录

TRL：详解

未来发展

成长机会带来的益处和影响
下一步
免责声明

简介目录

Product Code: DB4D

Emerging Tools Reshaping the Future of Gene Editing

This study highlights advancements such as prime editing, base editing, bridge RNA, SeekRNA, and gene writing platforms, as it examines the emerging field of next-generation gene editing technologies beyond CRISPR/Cas systems. These tools are revolutionary for therapeutic development, precision medicine, and functional genomics because they provide increased editing capabilities, decreased off-target effects, and improved precision. To improve accuracy and efficiency in genome engineering, the study highlights the use of artificial intelligence (AI) and machine learning for guide RNA optimization, off-target prediction, and scalable clinical translation. The collaborative innovation ecosystem is mapped by examining key stakeholders, including academic consortia, large pharmaceutical companies, biotech start-ups, and companies that provide AI-driven editing solutions. Additionally, to evaluate commercialization readiness, global funding trends, investment patterns, and regulatory environments in North America, Europe, Asia-Pacific, and emerging regions are examined. The study highlights how disruptive tools are changing the future of genetic medicine and biotechnology by spotting growth prospects and strategic partnerships.

Strategic Imperatives

Why Is It Increasingly Difficult to Grow?
The Strategic Imperative 8
The Impact of the Top 3 Strategic Imperatives on the Beyond CRISPR Rewriting DNA Space
Growth Opportunities Fuel the Growth Pipeline Engine
Research Methodology

Growth Opportunity Analysis

Scope of Analysis
Segmentation

Growth Generator

Growth Drivers
Growth Restraints

CRISPR Technology: Mechanism, Advantages, and Limitations

CRISPR-Clustered Regularly Interspaced Short Palindromic Repeats
Pros and Cons of CRISPR Gene Editing

Next-Generation Gene Editing Technologies

Prime Editing-Expanding Accuracy and Versatility in Gene Editing
Recent Innovations in Prime Editing
Bridge RNA-The Third Generation of Genetic Engineering
SeekRNA-A New Pathway for Accurate Gene Editing
Epigenome Editing
Base Editing: Unlocking Single-Nucleotide Precision
Recent Innovations in Base Editing
Gene Writing-A New Blueprint for Genome Engineering
Recent Innovations in Gene Writing

AI & Machine Learning in Gene Editing

AI and Machine Learning AI/ML in Gene Editing
Emerging Trends in Gene Editing and AI

Translating Gene Editing to Clinical Impact: Stakeholders and Solutions

Stakeholders Developing Gene Editing Technologies

Funding and Collaboration Landscape

Key Collaborations in Gene Editing Technologies-Global 2023-2025
Snapshot of Industry Funding-Global 2023-2025
Snapshot of Academia Funding-Global 2023-2025
Regional Trends in Gene Editing-Developments and Adoption

Growth Opportunity Universe-Beyond CRISPR Rewriting DNA

Growth Opportunity 1: AI-Driven Guide Design and Off-Target Prediction in Gene Editing
Growth Opportunity 2: Next-Generation Gene Editing Tools
Growth Opportunity 3: Large DNA Integration and Rewriting