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市场调查报告书
商品编码
1382479
酵素替代疗法市场规模 - 按酵素(Alglucosidase alfa、Agalsidase beta、Imiglucerase)、适应症(Gaucher、MPS、Pompe、SCID、Fabry)、给药途径、最终用户、2023-2032 年全球预测Enzyme Replacement Therapy Market Size - By Enzyme (Alglucosidase alfa, Agalsidase beta, Imiglucerase), Indication (Gaucher, MPS, Pompe, SCID, Fabry), Route of Administration, End-user, Global Forecast 2023-2032 |
由于生物製剂和各种遗传性疾病的标准治疗方法得到更广泛的接受,酵素替代疗法市场规模预计在 2023 年至 2032 年期间CAGR将超过 7%。
包括酵素替代疗法 (ERT) 在内的生物製剂作为戈谢病和法布瑞氏症等遗传性疾病的先进标靶治疗方法越来越受到重视。生物製剂的治疗功效和特异性以及随后在患者和医疗保健提供者中越来越多的采用也将促进市场成长。例如,2023年11月,武田的ADZYNMA获得美国FDA批准,成为第一个也是唯一一个用于治疗先天性血栓性血小板减少性紫斑症(cTTP)的重组ADAMTS13酶替代药物。
酵素替代疗法产业分为酵素类型、适应症、给药途径、最终使用者和地区。
就酵素类型而言,预计 2023 年至 2032 年伊米苷酶领域的市值CAGR将达到 8.4%。伊米苷酶已成为治疗戈谢氏症的有效酵素替代疗法。不断扩大的患者群体,加上对罕见疾病的认识和诊断不断提高,正在扩大对基于伊米苷酶的 ERT 的需求。此外,生物技术的不断进步和持续研究将有助于该领域的成长。
根据最终用户,输液中心领域的 ERT 产业到 2032 年可能会实现 7.5% 的CAGR。酵素缺乏症盛行率的上升,加上酵素替代疗法的接受度不断提高,将大大增加对输液中心服务的需求。此外,由于提供方便且受控的治疗环境,患者对输液中心的偏好不断增加,这可能会支持该细分市场的成长。
从地区来看,由于先进的医疗基础设施、意识的提高以及酵素缺乏症盛行率的上升,到 2032 年,欧洲酵素替代疗法市场规模预计将实现 6.8% 的CAGR。此外,欧洲製药公司和研究机构之间的合作将有助于促进 ERT 技术的进步。此外,越来越多的致力于透过创新疗法改善患者治疗结果将增强该地区的行业前景。例如,2023 年 5 月,欧盟委员会授予了 pegunigalsidase alfa 的营销授权,这是一种用于治疗法布瑞氏症的聚乙二醇 (PEG) 化酶。
Enzyme Replacement Therapy Market size is set to exhibit over 7% CAGR from 2023 to 2032, driven by the broader acceptance of biologics and standard treatments for various genetic disorders.
Biologics, including enzyme replacement therapy (ERT) are gaining prominence as advanced and targeted treatments for genetic disorders, such as Gaucher disease and Fabry disease. The therapeutic efficacy and specificity of biologics and the subsequently rising adoption amongst patients and healthcare providers will also boost the market growth. For instance, in November 2023, Takeda's ADZYNMA received clearance from the U.S. FDA as the first and only recombinant ADAMTS13 enzyme replacement medication for the treatment of congenital thrombotic thrombocytopenic purpura (cTTP).
The enzyme replacement therapy industry is segmented into enzyme type, indication, route of administration, end-user, and region.
With respect to enzyme type, the market value from imiglucerase segment is anticipated to attain 8.4% CAGR from 2023-2032. Imiglucerase has emerged as an effective enzyme replacement therapy for the treatment of Gaucher disease. The expanding patient pool coupled with the rising awareness and diagnosis of rare diseases is amplifying the demand for Imiglucerase-based ERTs. Moreover, the rising advancements in biotechnology and continuous research will contribute to the segment growth.
Based on end-user, the ERT industry from the infusion centers segment is likely to record 7.5% CAGR through 2032. The rising prevalence of enzyme deficiency disorders coupled with the increasing acceptance of enzyme replacement therapies is adding significantly to the demand for infusion center services. Additionally, the increasing patient preference for infusion centers due to the availability of convenient and controlled environment for the treatment is likely to support the segment growth.
Regionally, the Europe enzyme replacement therapy market size is slated to observe 6.8% CAGR through 2032 driven advanced healthcare infrastructure, increasing awareness, and the rising prevalence of enzyme deficiency disorders. Moreover, collaborations between pharmaceutical companies and research institutions in Europe will contribute to increasing advancements in ERT technologies. Additionally, the growing commitment to improving patient outcomes through innovative therapies will augment the regional industry outlook. For instance, in May 2023, the European Commission granted marketing authorization for pegunigalsidase alfa, the Poly (ethylene glycol) (PEG) ylated enzyme for Fabry disease.