吸入止痛药：不断发展的药物和新的商机

随着发达国家预期寿命的增加和人口老龄化，慢性和急性疼痛的发生率以及相关的发病率也在增加，这使得疼痛管理成为对患者及其家人而言更加重要的生活质量问题。这一点已经开始显现。

本报告考察了吸入止痛药市场，并概述了疼痛管理、监管环境、需求驱动因素分析、竞争格局和参与者概况。

内容

• 通过吸入治疗疼痛
• 执行摘要
• 疼痛管理市场机会
• 疼痛管理指南的演变
• 疼痛管理实践中的区域因素
• 疼痛管理的需求驱动因素
• 竞争格局
• 增长限制因素
• 吸入技术、平台、设计因素
• 制定
• 配方技术
• 辅料和释放曲线
• 口服吸入器的设计因素
• 干粉吸入器
• 固定剂量吸入器
• 雾化器
• 鼻内吸入
• 鼻内给药的药代动力学
• 鼻内器械的特点
• 绩效因素
• 生物利用度
• 剂量重现性
• 活性化合物的稳定性
• 吸入器的主要短期止痛市场
• 突破性癌痛 (cBTP)
• 偏头痛和丛集性头痛
• 中度至重度疼痛
• 吸入性镇痛产品
• FDA 批准的药物
• 阿斯利康
• 葛兰素史克
• 威朗特
• Mylan/Roxane/Apotex
• 酮咯酸
• 处于开发阶段的药物
• 布托啡诺
• 芬太尼
• 双氢麦角胺
• 氯胺酮
• 吗啡
• 全氯拉秦
• 曲坦类
• 市场因素
• 易于使用和患者偏好
• 监管问题
• 患者依从性
• CMO/CSO 的角色
• 公司简介

‘Inhaled Pain Management: Evolving Therapeutics, Emerging Opportunities’ is a comprehensive evaluation and analysis of the technology, products and participants providing the driving force behind this evolving segment of the healthcare sector.

The study is designed to provide drug company decision makers, drug delivery developers, device designers, healthcare marketers, and supply chain participants with a detailed understanding of the economics, technologies, disease segments, and commercial opportunities for inhaled pain management drug therapeutics. Provider organization business managers, healthcare administrators and investors will also benefit from this study.

User-friendly Administration for a Diverse and Growing Therapeutic Need

As life expectancy in the developed world increases and populations age, the incidence and associated morbidity of chronic and acute pain is increasing and placing a higher level of emphasis on pain management as a quality-of-life issue for patients and their families. Responding to this trend, drug developers are increasingly turning to inhalable formulations of pain management drugs. Because it has the potential to improve drug therapy compliance, inhaled pain drug delivery addresses a key healthcare issue - one that is particularly problematic in aging populations and developing economies. Several of these development programs involve international partnerships designed to take advantage of perceived opportunities in regional markets.

What You Will Learn:

• Analyzes and evaluates inhaled pain management drugs currently in development and assesses the market potential for existing and probable future products.

• Examines inhalation device technology for commercial and development-stage devices, and evaluates product technology issues and evolving market factors for inhaled pain management therapeutics.

• Provides detailed assessments of market segments, market potential, and growth prospects.

• Forecasts the impact of new and emerging inhaled pain management drug therapeutics on healthcare markets and prescribing decisions.

• Profiles Inhaled pain management drug product market participants, their technology, product development activity, and business strategies.

• Evaluates the impact of economic, technology, and regulatory factors on market sector companies and their alliance partners.

Table of Contents

• Inhaled Pain Management
• Executive Summary
• The Pain Management Market Opportunity
• Evolution in Pain Management Guidelines
• Regional Factors in Pain Management Practice
• Pain Management Demand Drivers
• Competitive Landscape
• Factors Limiting Growth
• Inhalation Technology, Platforms and Design Factors
• Drug Formulations
• Formulation Technologies
• Excipients and Release Profiles
• Oral Inhalation Device Design Factors
• Dry Powder Inhalers
• Metered Dose Inhalers
• Nebulizers
• Intranasal Inhalation
• Intranasal Delivery Pharmacokinetics
• Intranasal Device Characteristics
• Performance Factors
• Bioavailability
• Dose Reproducibility
• Active Compound Stability
• Key Near-Term Pain Markets for Inhaled Drugs
• Breakthrough Cancer Pain
• Migraine and Cluster Headaches
• Moderate to Severe Pain
• 1Inhaled Pain Management Products
• FDA-Approved Drugs
• AstraZeneca
• GlaxoSmithKline
• Valeant
• Mylan/Roxane/Apotex
• Ketorolac
• Development-Stage Drugs
• Butorphanol
• Fentanyl
• Dihydroergotamine
• Ketamine
• Morphine
• Perchlorperazine
• Triptans
• Market Factors
• Usability and Patient Preferences
• Regulatory Issues
• Patient Compliance
• The Role of CMOs/CSOs
• Company Profiles