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市场调查报告书
商品编码
1718480
治疗途径抗发炎药市场 - 技术,适应症,市场与预测Therapeutic Pathway Anti-Inflammatory Drugs & Markets, Technology, Indications, Markets & Forecasts |
本市场研究报告对推动药物传输领域这一不断增长的技术、产品和市场参与者进行了全面的评估和分析。本报告旨在让製药决策者、药物开发商和配方师、药物设备设计师和产业策略家详细了解吸入式中枢神经系统治疗对製药策略和医疗保健治疗方案日益增长的影响。它对于医疗保健组织的业务经理、医疗保健管理人员和投资者也将很有用。
向中枢神经系统注射药物面临独特的挑战。然而,药物开发商和研究人员发现,透过吸入方式输送中枢神经系统药物可以缓解其中的一些问题。鼻腔通路和血管系统为将小分子药物和生物製剂穿过血脑屏障输送到中枢神经系统提供了一个有吸引力的途径。深肺给药可能具有良好的药物动力学特性。与口服药物相比,吸入给药还可以提供更快的起效速度,且所需的给药频率更低。这些潜在的益处促进了针对多种疾病的吸入式中枢神经系统药物的开发。随着人口老化和管理式医疗计划促使家庭医疗保健和药物自我管理的扩大,吸入药物越来越被视为对患者友好且具有成本效益的药物。我们的分析表明,透过吸入进行中枢神经系统输送非常适合利用这些趋势,并发展成为未来药物开发和中枢神经系统治疗商业化的关键组成部分。
IL-23/IL-17 轴作为自体免疫的治疗标靶 IL-23/IL-17 轴在人类自体免疫疾病中变得重要,从而促使新型治疗药物的批准和快速开发。针对各种细胞激素或细胞激素受体的单株抗体以及针对 RORyt 和 JAK 的小分子抑制剂正在改变治疗格局,目前已有三十多种不同的产品获得批准或处于临床开发阶段。针对 IL-17 和 IL-17RA 的人源化单株抗体能够改善中度至重度干癣和干癣关节炎的治疗效果。
该研究方法以对主要市场参与者、技术开发商、分销商、行业专家和市场影响者(包括监管机构、行业协会和材料标准机构)进行深入访谈的形式进行初步研究。
根据行业期刊文章、技术文献、行业出版物、公司数据表和公开声明以及政府机构和行业协会的统计数据等二手资料来源对主要资讯进行评估和标准化。
使用标准建模和统计技术可以估计和预测市场需求和未来市场活动。
This new market study, "Therapeutic Pathway Anti-Inflammatory Drugs & Markets" is a comprehensive evaluation and analysis of the technology, products and participants providing the driving force behind this growing segment of the drug delivery sector. The report has been designed and developed to provide pharmaceutical company decision makers, drug developers and formulators, drug device designers, and industry strategists with a detailed understanding of the expanding impact of inhaled CNS therapies on pharmaceutical strategies and healthcare treatment protocols. Provider organization business managers, healthcare administrators and investors will also benefit from this publication.
Delivering drugs to the central nervous system presents unique challenges. But, drug developers and researchers have discovered that delivering CNS therapeutic drugs via inhalation mitigates several of these issues. The accessibility and vascular structure of the nose make it an attractive route for delivering both small molecule drugs and biologics across the blood-brain barrier to the CNS. Pulmonary delivery to the deep lung can have favorable pharmacokinetics. And inhaled delivery offers the potential for faster onset of action and less frequent dosing relative to oral drugs. These potential advantages have spurred activity in inhaled CNS therapeutics for a range of disorders. As aging population demographics and managed care initiatives drive growth in home health care and self-administration of drug therapies, inhaled medicine is increasingly being viewed as patient-friendly and cost-effective. Our analysis indicated that inhaled CNS administration is well positioned to take advantage of these trends and evolve into a significant factor in the future of pharmaceutical development and commercialization of CNS therapeutic drugs.
The IL-23/IL-17 axis as a therapeutic target in autoimmunity The identification of the IL-23/IL-17 axis as critical for human autoimmune disease has led to the approval and rapid development of novel therapeutic agents. Monoclonal antibodies to a variety of cytokines and cytokine receptors and small-molecule inhibitors of RORyt and JAKs are changing the therapeutic landscape, with three dozen distinct products now approved or in clinical development. Humanized monoclonal antibodies to both IL-17 and IL-17RA are enabling improved outcomes for moderate to severe psoriasis as well as psoriatic arthritis.
Research methodology is based on primary research in the form of in-depth interviews with key market participants, technology developers, distributors, industry experts, and market influencers, a list that includes regulatory officials, industry trade groups, and materials standards organizations.
Primary data is evaluated and normalized against secondary sources including trade journal articles, technical literature, industry publications, company data sheets and published information, and statistical data from government agencies and trade associations.
Forecasts and projections of market demand and future market activity are derived using standard modeling and statistical techniques.