Product Code: GVR-2-68038-559-5
Migraine Drugs Market Growth & Trends:
The global migraine drugs market size is expected to be valued at USD 13.34 billion by 2030, as per a new report by Grand View Research, Inc., exhibiting an 11.9% CAGR during the forecast period. The market is largely driven by factors such as a rise in disease prevalence, development of novel therapies, lifestyle changes, and hormonal medications.
Migraine is a debilitating neurological disease characterized by recurrent attacks of severe throbbing head pain that can last for more than three days. Migraine pain may get worse on movement, preventing the patient from carrying out normal, day-to-day activities. In about one-third of attacks, both sides of the head, face, or neck are affected.
Over the past five years, the global migraine drugs market has been relatively stagnant, with the market mainly dominated by usage of generic triptans and other off-label drugs. Majority of the currently prescribed drugs for both acute and preventative treatment are associated with poor efficacy and an unfavorable side-effect profile.
Launch of Amgen/ Novartis' CGRP mAb Aimovig and Teva Pharma's Ajovy is the first step toward revolutionizing the treatment paradigm of migraine prevention. For drug manufacturers likely to enter the market by 2019, such as Eli Lilly, Alder BioPharma, and Biohaven Pharma, pricing will be a key differentiating factor as all CGRP-based therapies have a similar efficacy and safety profile.
Migraine Drugs Market Report Highlights:
- Germany leads the European market, driven by rising disease prevalence, novel drug launches, and an increase in R&D activities
- The acute migraine treatment market will be supported by the rapid uptake of novel drug classes such as CGRP receptor antagonists and ditans currently under active investigation in multiple Phase II/III trials
- Biohaven's rimegepant is expected to face competition from Allergan's ubrogepant, which has shown superior efficacy in Phase III trials compared to rimegepant
- Eli Lilly's Phase III 5-HT1F receptor agonist Lasmiditan is expected to be a novel first-line non triptan acute treatment option for patients in whom triptans are contradicted
- Approximately 20% of patients seeking preventive treatment for migraine do not respond to available generic medications. Several biologics and small molecules drugs are undergoing active development to target high unmet needs in the preventive treatment segment
- Drugs with novel targets in early-phase development include AOBiome Therapeutics' AOB-203 (antibacterial), Winston Pharma's Dolorac (histamine H1 receptor antagonists), NeuroAxons' NXN-188 (a combination of NOS inhibitor and a triptan), and Biohaven's BHV-3500 (gepant). These novel agents are under evaluation for both episodic and chronic migraine in multiple Phase I/II trials.
Table of Contents
Chapter 1. Methodology and Scope
- 1.1. Market Segmentation & Scope
- 1.2. Segment Definitions
- 1.2.1. Treatment
- 1.2.2. Therapeutic Class
- 1.2.3. Route of Administration
- 1.2.4. Age Group
- 1.2.5. Availability
- 1.2.6. Regional scope
- 1.2.7. Estimates and forecasts timeline
- 1.3. Research Methodology
- 1.4. Information Procurement
- 1.4.1. Purchased database
- 1.4.2. GVR's internal database
- 1.4.3. Secondary sources
- 1.4.4. Primary research
- 1.4.5. Details of primary research
- 1.4.5.1. Data for primary interviews in North America
- 1.4.5.2. Data for primary interviews in Europe
- 1.4.5.3. Data for primary interviews in Asia Pacific
- 1.4.5.4. Data for primary interviews in Latin America
- 1.4.5.5. Data for Primary interviews in MEA
- 1.5. Information or Data Analysis
- 1.5.1. Data analysis models
- 1.6. Market Formulation & Validation
- 1.7. Model Details
- 1.7.1. Commodity flow analysis (Model 1)
- 1.7.2. Approach 1: Commodity flow approach
- 1.7.3. Volume price analysis (Model 2)
- 1.7.4. Approach 2: Volume price analysis
- 1.8. List of Secondary Sources
- 1.9. List of Primary Sources
- 1.10. Objectives
Chapter 2. Executive Summary
- 2.1. Market Outlook
- 2.2. Segment Outlook
- 2.2.1. Treatment Outlook
- 2.2.2. Therapeutic Class Outlook
- 2.2.3. Route of Administration Outlook
- 2.2.4. Age Group Outlook
- 2.2.5. Availability Outlook
- 2.2.6. Regional Outlook
- 2.3. Competitive Insights
Chapter 3. Migraine Drugs Market Variables, Trends & Scope
- 3.1. Market Lineage Outlook
- 3.1.1. Parent market outlook
- 3.1.2. Related/ancillary market outlook
- 3.2. Market Dynamics
- 3.2.1. Market Driver Analysis
- 3.2.1.1. Increasing prevalence of migraines
- 3.2.1.2. Advancements in drug development
- 3.2.1.3. Growing awareness and diagnosis
- 3.2.2. Market Restraint Analysis
- 3.2.2.1. High cost of development
- 3.2.2.2. Regulatory challenges for new drug approvals
- 3.3. Migraine Drugs Market Analysis Tools
- 3.3.1. Industry Analysis - Porter's
- 3.3.1.1. Supplier power
- 3.3.1.2. Buyer power
- 3.3.1.3. Substitution threat
- 3.3.1.4. Threat of new entrant
- 3.3.1.5. Competitive rivalry
- 3.3.2. PESTEL Analysis
- 3.3.2.1. Political landscape
- 3.3.2.2. Technological landscape
- 3.3.2.3. Economic landscape
- 3.3.3. Pipeline Analysis
- 3.3.4. Target population analysis
Chapter 4. Migraine Drugs Market: Treatment Estimates & Trend Analysis
- 4.1. Global Migraine Drugs Market: Treatment Dashboard
- 4.2. Global Migraine Drugs Market: Treatment Movement Analysis
- 4.3. Global Migraine Drugs Market by Treatment, Revenue
- 4.4. Acute
- 4.4.1. Acute market estimates and forecasts 2018 - 2030 (USD Million)
- 4.5. Preventive
- 4.5.1. Preventive market estimates and forecasts 2018 - 2030 (USD Million)
Chapter 5. Migraine Drugs Market: Therapeutic Class Estimates & Trend Analysis
- 5.1. Global Migraine Drugs Market: Therapeutic Class Dashboard
- 5.2. Global Migraine Drugs Market: Therapeutic Class Movement Analysis
- 5.3. Global Migraine Drugs Market Estimates and Forecasts, By Therapeutic Class, Revenue (USD Million)
- 5.4. CGRP Monoclonal Antibodies
- 5.4.1. CGRP monoclonal antibodies market estimates and forecasts 2018 - 2030 (USD Million)
- 5.5. CGRP Small Molecule Antagonists
- 5.5.1. CGRP small molecule antagonists market estimates and forecasts 2018 - 2030 (USD Million)
- 5.6. Acetylcholine Inhibitors/ neurotoxins
- 5.6.1. Acetylcholine inhibitors/ neurotoxins market estimates and forecasts 2018 - 2030 (USD Million)
- 5.7. Triptans
- 5.7.1. Triptans market estimates and forecasts 2018 - 2030 (USD Million)
- 5.8. Ditans
- 5.8.1. Ditans market estimates and forecasts 2018 - 2030 (USD Million)
- 5.9. Ergot alkaloids
- 5.9.1. Ergot alkaloids market estimates and forecasts 2018 - 2030 (USD Million)
- 5.10. NSAIDs
- 5.10.1. NSAIDs market estimates and forecasts 2018 - 2030 (USD Million)
- 5.11. Others
- 5.11.1. Others market estimates and forecasts 2018 - 2030 (USD Million)
Chapter 6. Migraine Drugs Market: Route of Administration Estimates & Trend Analysis
- 6.1. Global Migraine Drugs Market: Route of Administration Dashboard
- 6.2. Global Migraine Drugs Market: Route of Administration Movement Analysis
- 6.3. Global Migraine Drugs Market Estimates and Forecasts, by Route of Administration, Revenue (USD Million)
- 6.4. Oral
- 6.4.1. Oral market estimates and forecasts 2018 - 2030 (USD Million)
- 6.5. Injectable
- 6.5.1. Injectable market estimates and forecasts 2018 - 2030 (USD Million)
- 6.6. Others
- 6.6.1. Others market estimates and forecasts 2018 - 2030 (USD Million)
Chapter 7. Migraine Drugs Market: Age Group Estimates & Trend Analysis
- 7.1. Global Migraine Drugs Market: Age Group Dashboard
- 7.2. Global Migraine Drugs Market: Age Group Movement Analysis
- 7.3. Global Migraine Drugs Market Estimates and Forecasts by Age Group, Revenue (USD Million)
- 7.4. Pediatric
- 7.4.1. Pediatric market estimates and forecasts 2018 - 2030 (USD Million)
- 7.5. Adult
- 7.5.1. Adult market estimates and forecasts 2018 - 2030 (USD Million)
- 7.6. Geriatric
- 7.6.1. Geriatric market estimates and forecasts 2018 - 2030 (USD Million)
Chapter 8. Migraine Drugs Market: Availability Estimates & Trend Analysis
- 8.1. Global Migraine Drugs Market: Availability Dashboard
- 8.2. Global Migraine Drugs Market: Availability Movement Analysis
- 8.3. Global Migraine Drugs Market Estimates and Forecasts, by Availability, Revenue (USD Million)
- 8.4. Prescription Drugs
- 8.4.1. Prescription Drugs market estimates and forecasts 2018 - 2030 (USD Million)
- 8.5. Over-the-Counter (OTC) Drugs
- 8.5.1. Over-the-Counter (OTC) Drugs market estimates and forecasts 2018 - 2030 (USD Million)
Chapter 9. Migraine Drugs Market: Regional Estimates & Trend Analysis by Treatment, Therapeutic Class, Route of Administration, Age Groupd and Availability
- 9.1. Regional Dashboard
- 9.2. Market Size, & Forecasts Trend Analysis, 2018 - 2030
- 9.3. North America
- 9.3.1. U.S.
- 9.3.1.1. Key country dynamics
- 9.3.1.2. Regulatory framework/ reimbursement structure
- 9.3.1.3. Competitive scenario
- 9.3.1.4. U.S. market estimates and forecasts 2018 - 2030 (USD Million)
- 9.3.2. Canada
- 9.3.2.1. Key country dynamics
- 9.3.2.2. Regulatory framework/ reimbursement structure
- 9.3.2.3. Competitive scenario
- 9.3.2.4. Canada market estimates and forecasts 2018 - 2030 (USD Million)
- 9.3.3. Mexico
- 9.3.3.1. Key country dynamics
- 9.3.3.2. Regulatory framework/ reimbursement structure
- 9.3.3.3. Competitive scenario
- 9.3.3.4. Mexico market estimates and forecasts 2018 - 2030 (USD Million)
- 9.4. Europe
- 9.4.1. UK
- 9.4.1.1. Key country dynamics
- 9.4.1.2. Regulatory framework/ reimbursement structure
- 9.4.1.3. Competitive scenario
- 9.4.1.4. UK market estimates and forecasts 2018 - 2030 (USD Million)
- 9.4.2. Germany
- 9.4.2.1. Key country dynamics
- 9.4.2.2. Regulatory framework/ reimbursement structure
- 9.4.2.3. Competitive scenario
- 9.4.2.4. Germany market estimates and forecasts 2018 - 2030 (USD Million)
- 9.4.3. France
- 9.4.3.1. Key country dynamics
- 9.4.3.2. Regulatory framework/ reimbursement structure
- 9.4.3.3. Competitive scenario
- 9.4.3.4. France market estimates and forecasts 2018 - 2030 (USD Million)
- 9.4.4. Italy
- 9.4.4.1. Key country dynamics
- 9.4.4.2. Regulatory framework/ reimbursement structure
- 9.4.4.3. Competitive scenario
- 9.4.4.4. Italy market estimates and forecasts 2018 - 2030 (USD Million)
- 9.4.5. Spain
- 9.4.5.1. Key country dynamics
- 9.4.5.2. Regulatory framework/ reimbursement structure
- 9.4.5.3. Competitive scenario
- 9.4.5.4. Spain market estimates and forecasts 2018 - 2030 (USD Million)
- 9.4.6. Denmark
- 9.4.6.1. Key country dynamics
- 9.4.6.2. Regulatory framework/ reimbursement structure
- 9.4.6.3. Competitive scenario
- 9.4.6.4. Denmark market estimates and forecasts 2018 - 2030 (USD Million)
- 9.4.7. Norway
- 9.4.7.1. Key country dynamics
- 9.4.7.2. Regulatory framework/ reimbursement structure
- 9.4.7.3. Competitive scenario
- 9.4.7.4. Norway market estimates and forecasts 2018 - 2030 (USD Million)
- 9.4.8. Sweden
- 9.4.8.1. Key country dynamics
- 9.4.8.2. Regulatory framework/ reimbursement structure
- 9.4.8.3. Competitive scenario
- 9.4.8.4. Sweden market estimates and forecasts 2018 - 2030 (USD Million)
- 9.5. Asia Pacific
- 9.5.1. Japan
- 9.5.1.1. Key country dynamics
- 9.5.1.2. Regulatory framework/ reimbursement structure
- 9.5.1.3. Competitive scenario
- 9.5.1.4. Japan market estimates and forecasts 2018 - 2030 (USD Million)
- 9.5.2. China
- 9.5.2.1. Key country dynamics
- 9.5.2.2. Regulatory framework/ reimbursement structure
- 9.5.2.3. Competitive scenario
- 9.5.2.4. China market estimates and forecasts 2018 - 2030 (USD Million)
- 9.5.3. India
- 9.5.3.1. Key country dynamics
- 9.5.3.2. Regulatory framework/ reimbursement structure
- 9.5.3.3. Competitive scenario
- 9.5.3.4. India market estimates and forecasts 2018 - 2030 (USD Million)
- 9.5.4. Australia
- 9.5.4.1. Key country dynamics
- 9.5.4.2. Regulatory framework/ reimbursement structure
- 9.5.4.3. Competitive scenario
- 9.5.4.4. Australia market estimates and forecasts 2018 - 2030 (USD Million)
- 9.5.5. South Korea
- 9.5.5.1. Key country dynamics
- 9.5.5.2. Regulatory framework/ reimbursement structure
- 9.5.5.3. Competitive scenario
- 9.5.5.4. South Korea market estimates and forecasts 2018 - 2030 (USD Million)
- 9.5.6. Thailand
- 9.5.6.1. Key country dynamics
- 9.5.6.2. Regulatory framework/ reimbursement structure
- 9.5.6.3. Competitive scenario
- 9.5.6.4. Thailand market estimates and forecasts 2018 - 2030 (USD Million)
- 9.6. Latin America
- 9.6.1. Brazil
- 9.6.1.1. Key country dynamics
- 9.6.1.2. Regulatory framework/ reimbursement structure
- 9.6.1.3. Competitive scenario
- 9.6.1.4. Brazil market estimates and forecasts 2018 - 2030 (USD Million)
- 9.6.2. Argentina
- 9.6.2.1. Key country dynamics
- 9.6.2.2. Regulatory framework/ reimbursement structure
- 9.6.2.3. Competitive scenario
- 9.6.2.4. Argentina market estimates and forecasts 2018 - 2030 (USD Million)
- 9.7. MEA
- 9.7.1. South Africa
- 9.7.1.1. Key country dynamics
- 9.7.1.2. Regulatory framework/ reimbursement structure
- 9.7.1.3. Competitive scenario
- 9.7.1.4. South Africa market estimates and forecasts 2018 - 2030 (USD Million)
- 9.7.2. Saudi Arabia
- 9.7.2.1. Key country dynamics
- 9.7.2.2. Regulatory framework/ reimbursement structure
- 9.7.2.3. Competitive scenario
- 9.7.2.4. Saudi Arabia market estimates and forecasts 2018 - 2030 (USD Million)
- 9.7.3. UAE
- 9.7.3.1. Key country dynamics
- 9.7.3.2. Regulatory framework/ reimbursement structure
- 9.7.3.3. Competitive scenario
- 9.7.3.4. UAE market estimates and forecasts 2018 - 2030 (USD Million)
- 9.7.4. Kuwait
- 9.7.4.1. Key country dynamics
- 9.7.4.2. Regulatory framework/ reimbursement structure
- 9.7.4.3. Competitive scenario
- 9.7.4.4. Kuwait market estimates and forecasts 2018 - 2030 (USD Million)
Chapter 10. Competitive Landscape
- 10.1. Recent Developments & Impact Analysis, By Key Market Participants
- 10.2. Company/Competition Categorization
- 10.3. Vendor Landscape
- 10.3.1. List of key distributors and channel partners
- 10.3.2. Key customers
- 10.3.3. Key company market share analysis, 2023
- 10.3.4. AbbVie Inc.
- 10.3.4.1. Company overview
- 10.3.4.2. Financial performance
- 10.3.4.3. Product benchmarking
- 10.3.4.4. Strategic initiatives
- 10.3.5. Amgen Inc.
- 10.3.5.1. Company overview
- 10.3.5.2. Financial performance
- 10.3.5.3. Product benchmarking
- 10.3.5.4. Strategic initiatives
- 10.3.6. Teva Pharmaceutical Industries Ltd.
- 10.3.6.1. Company overview
- 10.3.6.2. Financial performance
- 10.3.6.3. Product benchmarking
- 10.3.6.4. Strategic initiatives
- 10.3.7. GSK plc
- 10.3.7.1. Company overview
- 10.3.7.2. Financial performance
- 10.3.7.3. Product benchmarking
- 10.3.7.4. Strategic initiatives
- 10.3.8. Eli Lilly and Company
- 10.3.8.1. Company overview
- 10.3.8.2. Financial performance
- 10.3.8.3. Product benchmarking
- 10.3.8.4. Strategic initiatives
- 10.3.9. Pfizer Inc.
- 10.3.9.1. Company overview
- 10.3.9.2. Financial performance
- 10.3.9.3. Product benchmarking
- 10.3.9.4. Strategic initiatives
- 10.3.10. Bausch Health Companies Inc.
- 10.3.10.1. Company overview
- 10.3.10.2. Financial performance
- 10.3.10.3. Product benchmarking
- 10.3.10.4. Strategic initiatives
- 10.3.11. Gensco Pharma
- 10.3.11.1. Company overview
- 10.3.11.2. Financial performance
- 10.3.11.3. Product benchmarking
- 10.3.11.4. Strategic initiatives
- 10.3.12. Impel Pharmaceuticals Inc.
- 10.3.12.1. Company overview
- 10.3.12.2. Financial performance
- 10.3.12.3. Product benchmarking
- 10.3.12.4. Strategic initiatives
- 10.3.13. Currax Pharmaceuticals LLC.
- 10.3.13.1. Company overview
- 10.3.13.2. Financial performance
- 10.3.13.3. Product benchmarking
- 10.3.13.4. Strategic initiatives
- 10.3.14. Lundbeck
- 10.3.14.1. Company overview
- 10.3.14.2. Financial performance
- 10.3.14.3. Product benchmarking
- 10.3.14.4. Strategic initiatives