Product Code: GVR-1-68038-473-4
Protein Expression Market Growth & Trends:
The global protein expression market size is expected to reach USD 6.51 billion by 2030, according to a new report by Grand View Research, Inc., expanding at a CAGR of 10.22% from 2024 to 2030. The increasing research in proteomics and genomics, the rising incidence of chronic diseases, and escalating demand for biologic products around the globe are enhancing the demand for protein expression, which is likely to drive the market. For instance, in April 2022, in a research published on Frontiers Media S.A., researchers differentially expressed 22 proteins to identify potential diagnostic biomarkers for Multiple Sclerosis (MS).
An increase in R&D investments by the players is estimated to have a considerable impact on the usage of protein expression. In August 2022, the managing director of Biocon Biologics stated in one of his interviews that the overall cost of the R&D is 12-14% of revenues. The investment is essential to build a sustainable portfolio of around 20 biosimilar molecules and the company is anticipated to launch at least once every 1-2 years. The approximate cost of developing these molecules is USD 50-100 million.
Other determinants such as rapid acceleration in the demand for protein therapeutics and government investment in the applications of the protein expression industry are also supporting the market growth. For instance, in May 2022, Proteomics International Laboratories was awarded approximately USD 286,833 funding from the Australian Government under the Medical Research Future Fund (MRFF) initiative. The funding is expected to support the manufacturing of the PromarkerD test in Australia. Such financial assistances are likely to supplement the market growth in the coming years.
The outbreak of the COVID-19 pandemic developed the urge to profile and conduct differential gene expression analyses on COVID-19 patients. Research published in Briefings in Bioinformatics, March 2021, employed the data of protein-drug interaction to identify the prospective drugs for COVID-19. As a result, the usage of the process is projected to upsurge during the COVID-19 pandemic and contribute to market growth.
The growing requirement for personalized therapy and vaccine is expected to be the key factor fueling the market growth during the forecast period. For instance, in January 2022, Amgen announced a collaboration with Generate Biomedicines to discover and develop protein therapeutics for various areas. The companies are estimating the worth of this collaboration around USD 1.9 billion.
The increasing development of recombinant proteins for industrial use, such as the production of food and beverages, is anticipated to boost the use of protein expression in the non-healthcare sector. However, the retail pricings of recombinant proteins for industrial and pharmaceutical uses are drastically different as pharmaceutical proteins are sold for billions of dollars per kg, while industrial proteins for tens of dollars per kg. R&D, clinical trials, and patents are the additional requirements of pharmaceutical proteins.
Protein Expression Market Report Highlights:
- The prokaryotic segment held the largest market share of 41.37% in 2023. Since it is relatively easier to handle and fulfill major purposes in research.
- In 2023, reagents dominated the market with a leading market share of 44.44%. The market consists of mature players such as Agilent Technologies, Inc.
- The therapeutic segment held the highest market share with 52.05% in 2023. Since protein therapeutic poses numerous advantages over other medications.
- The pharmaceutical and biotechnological companies segment held the maximum market share in 2023 with 46.50%.
- North America protein expression market dominated the global market with a 36.11% share in 2023.
Table of Contents
Chapter 1. Methodology and Scope
- 1.1. Market Segmentation and Scope
- 1.2. Market Definitions
- 1.2.1. Expression Systems
- 1.2.2. Product
- 1.2.3. Application
- 1.2.4. End Use
- 1.3. Information analysis
- 1.4. Market formulation & data visualization
- 1.5. Data validation & publishing
- 1.6. Information Procurement
- 1.7. Information or Data Analysis
- 1.8. Market Formulation & Validation
- 1.9. Market Model
- 1.10. Objectives
Chapter 2. Executive Summary
- 2.1. Market Outlook
- 2.2. Segment Snapshot
- 2.3. Competitive Landscape Snapshot
Chapter 3. Protein Expression Market Variables, Trends & Scope
- 3.1. Market Lineage Outlook
- 3.1.1. Parent market outlook
- 3.1.2. Related/ancillary market outlook.
- 3.2. Market Dynamics
- 3.2.1. Market driver analysis
- 3.2.1.1. Escalating Demand for Biologics
- 3.2.1.2. Increasing Investment In R&D
- 3.2.1.3. Rising Funding By Government For Proteomics And Genomics Research
- 3.2.2. Market restraint analysis
- 3.2.2.1. Stringent government rules and regulations
- 3.3. Protein Expression Market Analysis Tools
- 3.3.1. Industry Analysis - Porter's
- 3.3.2. PESTEL Analysis
- 3.3.3. COVID-19 Impact Analysis
Chapter 4. Protein Expression Market: Expression Systems Estimates & Trend Analysis
- 4.1. Segment Dashboard
- 4.2. Global Protein Expression Market Expression Systems Movement Analysis
- 4.3. Global Protein Expression Market Size & Trend Analysis, by Expression Systems, 2018 to 2030 (USD Million)
- 4.4. Prokaryotic
- 4.4.1. Prokaryotic market estimates and forecasts 2018 to 2030 (USD Million)
- 4.5. Mammalian Cell
- 4.5.1. Mammalian cell market estimates and forecasts 2018 to 2030 (USD Million)
- 4.6. Insect Cell
- 4.6.1. Insect cell market estimates and forecasts 2018 to 2030 (USD Million)
- 4.7. Yeast
- 4.7.1. Yeast market estimates and forecasts 2018 to 2030 (USD Million)
- 4.8. Others
- 4.8.1. Others market estimates and forecasts 2018 to 2030 (USD Million)
Chapter 5. Protein Expression Market: Product Estimates & Trend Analysis
- 5.1. Segment Dashboard
- 5.2. Global Protein Expression Market Product Movement Analysis
- 5.3. Global Protein Expression Market Size & Trend Analysis, by Product, 2018 to 2030 (USD Million)
- 5.4. Reagents
- 5.4.1. Reagents market estimates and forecasts 2018 to 2030 (USD Million)
- 5.5. Competent Cells
- 5.5.1. Competent cells market estimates and forecasts 2018 to 2030 (USD Million)
- 5.6. Expression Vectors
- 5.6.1. Expression vectors market estimates and forecasts 2018 to 2030 (USD Million)
- 5.7. Services
- 5.7.1. Services market estimates and forecasts 2018 to 2030 (USD Million)
- 5.8. Instrument
- 5.8.1. Instrument market estimates and forecasts 2018 to 2030 (USD Million)
Chapter 6. Protein Expression Market: Application Estimates & Trend Analysis
- 6.1. Segment Dashboard
- 6.2. Global Protein Expression Market Application Movement Analysis
- 6.3. Global Protein Expression Market Size & Trend Analysis, by Application, 2018 to 2030 (USD Million)
- 6.4. Therapeutic
- 6.4.1. Therapeutic market estimates and forecasts 2018 to 2030 (USD Million)
- 6.5. Industrial
- 6.5.1. Industrial market estimates and forecasts 2018 to 2030 (USD Million)
- 6.6. Research
- 6.6.1. Research market estimates and forecasts 2018 to 2030 (USD Million)
Chapter 7. Protein Expression Market: End Use Estimates & Trend Analysis
- 7.1. Segment Dashboard
- 7.2. Global Protein Expression Market End Use Movement Analysis
- 7.3. Global Protein Expression Market Size & Trend Analysis, by End Use, 2018 to 2030 (USD Million)
- 7.4. Pharmaceutical and biotechnological companies
- 7.4.1. Pharmaceutical and biotechnological companies market estimates and forecasts 2018 to 2030 (USD Million)
- 7.5. Academic research
- 7.5.1. Academic research market estimates and forecasts 2018 to 2030 (USD Million)
- 7.6. Contract research organizations
- 7.6.1. Contract research organizations market estimates and forecasts 2018 to 2030 (USD Million)
- 7.7. Others
- 7.7.1. Others market estimates and forecasts 2018 to 2030 (USD Million)
Chapter 8. Protein Expression Market: Regional Estimates & Trend Analysis by Expression Systems, Product, Application, and End Use
- 8.1. Regional Market Share Analysis, 2023 & 2030
- 8.2. Regional Market Dashboard
- 8.3. Market Size, & Forecasts Trend Analysis, 2018 to 2030:
- 8.4. North America
- 8.4.1. North America market estimates and forecasts 2018 to 2030 (USD Million)
- 8.4.2. U.S.
- 8.4.2.1. Key country dynamics
- 8.4.2.2. Regulatory framework
- 8.4.2.3. Competitive scenario
- 8.4.2.4. U.S. market estimates and forecasts 2018 to 2030 (USD Million)
- 8.4.3. Canada
- 8.4.3.1. Key country dynamics
- 8.4.3.2. Regulatory framework
- 8.4.3.3. Competitive scenario
- 8.4.3.4. Canada market estimates and forecasts 2018 to 2030 (USD Million)
- 8.4.4. Mexico
- 8.4.4.1. Key country dynamics
- 8.4.4.2. Regulatory framework
- 8.4.4.3. Competitive scenario
- 8.4.4.4. Mexico market estimates and forecasts 2018 to 2030 (USD Million)
- 8.5. Europe
- 8.5.1. Europe market estimates and forecasts 2018 to 2030 (USD Million)
- 8.5.2. UK
- 8.5.2.1. Key country dynamics
- 8.5.2.2. Regulatory framework
- 8.5.2.3. Competitive scenario
- 8.5.2.4. UK market estimates and forecasts 2018 to 2030 (USD Million)
- 8.5.3. Germany
- 8.5.3.1. Key country dynamics
- 8.5.3.2. Regulatory framework
- 8.5.3.3. Competitive scenario
- 8.5.3.4. Germany market estimates and forecasts 2018 to 2030 (USD Million)
- 8.5.4. France
- 8.5.4.1. Key country dynamics
- 8.5.4.2. Regulatory framework
- 8.5.4.3. Competitive scenario
- 8.5.4.4. France market estimates and forecasts 2018 to 2030 (USD Million)
- 8.5.5. Italy
- 8.5.5.1. Key country dynamics
- 8.5.5.2. Regulatory framework
- 8.5.5.3. Competitive scenario
- 8.5.5.4. Italy market estimates and forecasts 2018 to 2030 (USD Million)
- 8.5.6. Spain
- 8.5.6.1. Key country dynamics
- 8.5.6.2. Regulatory framework
- 8.5.6.3. Competitive scenario
- 8.5.6.4. Spain market estimates and forecasts 2018 to 2030 (USD Million)
- 8.5.7. Norway
- 8.5.7.1. Key country dynamics
- 8.5.7.2. Regulatory framework
- 8.5.7.3. Competitive scenario
- 8.5.7.4. Norway market estimates and forecasts 2018 to 2030 (USD Million)
- 8.5.8. Sweden
- 8.5.8.1. Key country dynamics
- 8.5.8.2. Regulatory framework
- 8.5.8.3. Competitive scenario
- 8.5.8.4. Sweden market estimates and forecasts 2018 to 2030 (USD Million)
- 8.5.9. Denmark
- 8.5.9.1. Key country dynamics
- 8.5.9.2. Regulatory framework
- 8.5.9.3. Competitive scenario
- 8.5.9.4. Denmark market estimates and forecasts 2018 to 2030 (USD Million)
- 8.6. Asia Pacific
- 8.6.1. Asia Pacific market estimates and forecasts 2018 to 2030 (USD Million)
- 8.6.2. Japan
- 8.6.2.1. Key country dynamics
- 8.6.2.2. Regulatory framework
- 8.6.2.3. Competitive scenario
- 8.6.2.4. Japan market estimates and forecasts 2018 to 2030 (USD Million)
- 8.6.3. China
- 8.6.3.1. Key country dynamics
- 8.6.3.2. Regulatory framework
- 8.6.3.3. Competitive scenario
- 8.6.3.4. China market estimates and forecasts 2018 to 2030 (USD Million)
- 8.6.4. India
- 8.6.4.1. Key country dynamics
- 8.6.4.2. Regulatory framework
- 8.6.4.3. Competitive scenario
- 8.6.4.4. India market estimates and forecasts 2018 to 2030 (USD Million)
- 8.6.5. Australia
- 8.6.5.1. Key country dynamics
- 8.6.5.2. Regulatory framework
- 8.6.5.3. Competitive scenario
- 8.6.5.4. Australia market estimates and forecasts 2018 to 2030 (USD Million)
- 8.6.6. South Korea
- 8.6.6.1. Key country dynamics
- 8.6.6.2. Regulatory framework
- 8.6.6.3. Competitive scenario
- 8.6.6.4. South Korea market estimates and forecasts 2018 to 2030 (USD Million)
- 8.6.7. Thailand
- 8.6.7.1. Key country dynamics
- 8.6.7.2. Regulatory framework
- 8.6.7.3. Competitive scenario
- 8.6.7.4. Thailand market estimates and forecasts 2018 to 2030 (USD Million)
- 8.7. Latin America
- 8.7.1. Latin America market estimates and forecasts 2018 to 2030 (USD Million)
- 8.7.2. Brazil
- 8.7.2.1. Key country dynamics
- 8.7.2.2. Regulatory framework
- 8.7.2.3. Competitive scenario
- 8.7.2.4. Brazil market estimates and forecasts 2018 to 2030 (USD Million)
- 8.7.3. Argentina
- 8.7.3.1. Key country dynamics
- 8.7.3.2. Regulatory framework
- 8.7.3.3. Competitive scenario
- 8.7.3.4. Argentina market estimates and forecasts 2018 to 2030 (USD Million)
- 8.8. MEA
- 8.8.1. MEA market estimates and forecasts 2018 to 2030 (USD Million)
- 8.8.2. South Africa
- 8.8.2.1. Key country dynamics
- 8.8.2.2. Regulatory framework
- 8.8.2.3. Competitive scenario
- 8.8.2.4. South Africa market estimates and forecasts 2018 to 2030 (USD Million)
- 8.8.3. Saudi Arabia
- 8.8.3.1. Key country dynamics
- 8.8.3.2. Regulatory framework
- 8.8.3.3. Competitive scenario
- 8.8.3.4. Saudi Arabia market estimates and forecasts 2018 to 2030 (USD Million)
- 8.8.4. UAE
- 8.8.4.1. Key country dynamics
- 8.8.4.2. Regulatory framework
- 8.8.4.3. Competitive scenario
- 8.8.4.4. UAE market estimates and forecasts 2018 to 2030 (USD Million)
- 8.8.5. Kuwait
- 8.8.5.1. Key country dynamics
- 8.8.5.2. Regulatory framework
- 8.8.5.3. Competitive scenario
- 8.8.5.4. Kuwait market estimates and forecasts 2018 to 2030 (USD Million)
Chapter 9. Competitive Landscape
- 9.1. Company/Competition Categorization
- 9.2. Strategy Mapping
- 9.3. Company Market Position Analysis, 2023
- 9.4. Company Profiles/Listing
- 9.4.1. Agilent Technologies, Inc.
- 9.4.1.1. Company overview
- 9.4.1.2. Financial performance
- 9.4.1.3. Product benchmarking
- 9.4.1.4. Strategic initiatives
- 9.4.2. Bio-Rad Laboratories
- 9.4.2.1. Company overview
- 9.4.2.2. Financial performance
- 9.4.2.3. Product benchmarking
- 9.4.2.4. Strategic initiatives
- 9.4.3. Edward Lifesciences
- 9.4.3.1. Company overview
- 9.4.3.2. Product benchmarking
- 9.4.3.3. Strategic initiatives
- 9.4.4. Thermo Fisher Scientific, Inc.
- 9.4.4.1. Company overview
- 9.4.4.2. Financial performance
- 9.4.4.3. Product benchmarking
- 9.4.4.4. Strategic initiatives
- 9.4.5. Merck Millipore
- 9.4.5.1. Company overview
- 9.4.5.2. Financial performance
- 9.4.5.3. Product benchmarking
- 9.4.5.4. Strategic initiatives
- 9.4.6. New England BioLabs, Inc.
- 9.4.6.1. Company overview
- 9.4.6.2. Product benchmarking
- 9.4.6.3. Strategic initiatives
- 9.4.7. Promega Corporation
- 9.4.7.1. Company overview
- 9.4.7.2. Financial performance
- 9.4.7.3. Product benchmarking
- 9.4.7.4. Strategic initiatives
- 9.4.8. QIAGEN
- 9.4.8.1. Company overview
- 9.4.8.2. Financial performance
- 9.4.8.3. Product benchmarking
- 9.4.8.4. Strategic initiatives
- 9.4.9. Takara Bio, Inc.
- 9.4.9.1. Company overview
- 9.4.9.2. Financial performance
- 9.4.9.3. Product benchmarking
- 9.4.9.4. Strategic initiatives
- 9.4.10. Oxford Expression Technologies
- 9.4.10.1. Company overview
- 9.4.10.2. Financial performance
- 9.4.10.3. Product benchmarking
- 9.4.10.4. Strategic initiatives
- 9.4.11. Lucigen Corporation
- 9.4.11.1. Company overview
- 9.4.11.2. Product benchmarking
- 9.4.11.3. Strategic initiatives