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市场调查报告书
商品编码
1571437

基因毒性测试市场规模、份额、趋势分析报告：按类型、按产品、按测定、按应用、按地区、细分市场预测，2024-2030 年

Genetic Toxicology Testing Market Size, Share & Trends Analysis Report By Type (In Vitro, In Vivo), By Product (Reagents & Consumables, Assays Kit, Services), By Assay, By Application, By Region, And Segment Forecasts, 2024 - 2030
出版日期: | 出版商: Grand View Research | 英文 100 Pages | 商品交期: 2-10个工作天内

价格
简介目录

遗传毒性测试市场的成长和趋势：

Grand View Research, Inc.的最新报告显示，预计到2030年，全球基因毒性检测市场规模将达到35.7亿美元，2024年至2030年的复合年增长率为11.6%。

个人化药物的日益普及，加上全球细胞和基因疗法的进步，正在推动对基因毒性的需求。例如，美国FDA 为细胞和基因治疗製造商制定了指导文件。根据该指南，临床前研究中毒性和生理参数鑑定的资讯将指南临床实验药物的临床监测。

越来越多地采用药物基因组学来支持个人化医疗并降低药物不良毒性风险，预计将对产业的成长产生重大影响。此外，荷兰药物遗传学工作组 (DPWG)、临床药物遗传学实施联盟 (CPIC)、法国国家药物遗传学网络和加拿大药物基因组药物安全网络 (CPNDS) 等组织支持药物基因组学测试的解释和我们发布了针对基因组合的建议的临床指南。

同样，市场参与者正在采取各种策略来扩大其在多个细分市场的足迹。例如，2021年11月，Labcorp宣布收购提供非临床测试服务的CRO Toxikon。此次收购预计将加强 Labcorp 的毒理学业务，而 Toxikon 的位置将使 Labcorp 能够与该地区的知名生物技术和製药公司开展非临床业务。

预计 COVID-19 大流行将对基因毒性测试市场的成长产生中性影响。许多研究人员正在利用基因毒性来评估药物对抗 COVID-19 病毒的有效性。例如，2020年9月，一个研究小组评估了Chloroquine（CQ）和羟氯喹（HCQ）作为病毒预防药物的效果。评估了各种药物和化学物质的遗传毒性。此类使用基因毒性测试作为评估工具的研究预计将支持 COVID-19 高峰期间的稳定增长。

对新型食品及其进口产品的需求不断增长预计将促进市场成长。 Charles River Laboratories 是新型食品毒理学评估的主要企业之一。该公司提供新颖的食品检测，包括遗传毒性，包括体内微核试验、艾姆斯试验、体外哺乳动物细胞微核试验和体内彗星试验。同样，2021 年 1 月，欧洲食品安全局 (EFSA) 发布了对昆虫食品的评估。这是该机构首次对昆虫产品作为新型食品进行此类评估。欧洲食品安全局每年都会收到大量申请，其中包括基于藻类食品、植物和非本地水果的草药产品。

另一方面，遗传毒理学的资讯搜寻能力有限。根据病理学测试解释组织的说法，基因测试提供有关特定疾病或正在测试的基因的资讯。儘管未经测试，但它不涵盖有关可能存在的其他遗传疾病的资讯。同样，我们无法辨识所有导致疾病的基因突变，也无法显示疾病的严重程度。因此，这些限制预计将阻碍基因毒性测试行业的成长。

基因毒性测试市场报告亮点

  • 按类型划分，试管内细分市场在 2023 年占据最大收益占有率，达到 65.1%，预计在估计和预测期内将保持类似的势头。这是由于成本效益、快速结果、减少动物使用、伦理考虑、监管接受、技术进步以及对各种产品的遗传毒性测试的认识提高等好处。
  • 按应用划分，製药和生物技术领域占最大的销售份额，2023年将达到44.9%。
  • 按产品划分，服务业在 2023 年占据最大收益占有率，达到 52.1%。这是由于多种因素造成的，包括对外包服务的需求增加、测试程序的复杂性增加以及对专业知识的需求。
  • 从分析来看，彗星分析领域将在 2023 年占据市场主导地位。彗星测定，也称为单细胞凝胶电泳测定，广泛用于评估 DNA 损伤。彗星检测可以检测多种 DNA 损伤，包括单链、双链和不完全修復位点。
  • 北美基因毒性测试市场在2023年以40.1%的收益占有率主导全球市场。该地区的优势是由于强大的管道投资而增加了药物开发。
  • 预计亚太地区在预测期内将以最快的复合年增长率扩张。这是因为日本和印度等国家正在收紧有关新食品和药物开发测试的法规。

目录

第一章调查方法和范围

第 2 章执行摘要

第 3 章 基因毒性测试市场变数、趋势和范围

  • 市场介绍/系统展望
  • 市场规模及成长前景
  • 市场动态
    • 市场驱动因素分析
    • 市场限制因素分析
  • 遗传毒性测试市场分析工具
    • 波特的分析
    • PESTEL分析

第四章基因毒性测试市场：产品估算与趋势分析

  • 细分仪表板
  • 基因毒性测试市场：产品变异分析，百万美元，2023 年和 2030 年
  • 试剂/耗材
  • 检测试剂套件
  • 服务

第五章基因毒性测试市场：类型估计和趋势分析

  • 细分仪表板
  • 基因毒性测试市场：类型变异分析，百万美元，2023-2030
  • In vitro
  • In vivo

第六章 基因毒性测试市场：含量估算与趋势分析

  • 细分仪表板
  • 基因毒性测试市场：检测变异分析，百万美元，2023 年和 2030 年
  • 彗星试验
  • 微核试验
  • 染色体异常检测
  • 基因突变检测
  • 其他的

第七章 基因毒性测试市场：应用估算与趋势分析

  • 细分仪表板
  • 基因毒性测试市场：应用变异分析，百万美元，2023 年和 2030 年
  • 製药/生物技术
  • 食品工业
  • 化妆品产业
  • 其他的

第八章基因毒性测试市场：区域估计和趋势分析

  • 2023 年和 2030 年按地区分類的基因毒性测试市场占有率，百万美元
  • 北美洲
    • 美国
    • 加拿大
    • 墨西哥
  • 欧洲
    • 英国
    • 德国
    • 法国
    • 义大利
    • 西班牙
    • 丹麦
    • 瑞典
    • 挪威
  • 亚太地区
    • 日本
    • 中国
    • 印度
    • 澳洲
    • 韩国
    • 泰国
  • 拉丁美洲
    • 巴西
    • 阿根廷
  • 中东/非洲
    • 南非
    • 沙乌地阿拉伯
    • 阿拉伯聯合大公国
    • 科威特

第9章 竞争格局

  • 最新趋势与影响分析：主要市场参与企业
  • 公司分类
  • 企业热力图分析
  • 公司简介
    • Thermo Fisher Scientific, Inc.
    • Charles River Laboratories
    • Laboratory Corporation of America Holdings
    • Eurofins Scientific
    • Jubilant Ingrevia Limited.
    • Syngene International Limited
    • Gentronix, Inotiv
    • Creative Bioarray
    • MB Research Laboratories
简介目录
Product Code: GVR-4-68039-981-3

Genetic Toxicology Testing Market Growth & Trends:

The global genetic toxicology testing market size is anticipated to reach USD 3.57 billion by 2030, registering to grow at a CAGR of 11.6% from 2024 to 2030, according to a new report by Grand View Research, Inc. The rising usage of personalized medicines, combined with the development of cell and gene therapy across the globe is enhancing the demand for genotoxicity. For instance, the U.S. FDA has designed guidance documents for the manufacturers of cell and gene therapy. According to the guidance, information on the identification of toxicities and physiologic parameters in preclinical studies can assist in guiding clinical monitoring for the investigational product.

Increasing implementation of pharmacogenomics to support personalized medicine usage and reduced risk of adverse drug toxicity is considered to have a significant impact on the growth of the industry. Moreover, organizations, such as the Dutch Pharmacogenetics Working Group (DPWG), Clinical Pharmacogenetics Implementation Consortium (CPIC), the French National Network of Pharmacogenetics, and the Canadian Pharmacogenomics Network for Drug Safety (CPNDS), have issued clinical guidelines with a primary focus on the pharmacogenomics testing interpretation and recommendation on therapeutic specific drug-gene pairs.

Similarly, the market players are indulging in various strategies to expand their footprint in multiple segments. For instance, in November 2021, Labcorp announced the acquisition of Toxikon, a Contract Research Organization (CRO) with offerings in nonclinical testing services. Through this acquisition, Labcorp is anticipated to strengthen its toxicology business and Toxikon's location enables Labcorp to engage with known biotech and pharmaceutical companies in the region for non-clinical work.

The COVID-19 pandemic is anticipated to have a neutral impact on the genetic toxicology testing market growth. Numerous researchers employed genotoxic to assess the effects of drugs against the COVID-19 virus. For instance, in September 2020, a team of researchers evaluated the impact of Chloroquine (CQ) and Hydroxychloroquine (HCQ) as prophylactic drugs against the virus. The genetic toxicology of various drugs and chemicals was assessed. Such studies using genetic toxicology testing as a tool of assessment are anticipated to support stable growth during the peak of COVID-19.

The rising demand for novel food and its imports is expected to be a contributor to market growth. Charles River Laboratories is one of the major players offering toxicology assessments on novel foods. They offer novel food analysis including genotoxicity, which consist of in vivo micronucleus test, Ames study, In Vitro Mammalian Cell Micronucleus, and in the vivo comet assay. Similarly, in January 2021, EFSA published its evaluation of insect-derived food. It is the first kind of assessment conducted by the institution on the insect product as a novel food. Every year, EFSA receives a large number of applications, consisting of herbal products based on algae foods, plants, and non-indigenous fruits.

On the other hand, the ability to retrieve information through genetic toxicology is limited. According to the Pathology Tests Explained organization, genetic tests offer information regarding the specific diseases/gene that is being tested. It does not cover information about other genetic diseases that might be present but have not been tested. Similarly, it cannot identify all the variations of genes that cause the diseases, and also it does not showcase the severity of the diseases. Hence, these limitations are anticipated to hamper the growth of the genetic toxicology industry.

Genetic Toxicology Testing Market Report Highlights:

  • By type, the in vitro segment held the largest revenue share of 65.1% in 2023 and is estimated to have similar momentum during the forecast period. This is attributed to advantages which include cost-effectiveness, faster results, reduced animal usage, ethical considerations, regulatory acceptance advancements in technology, and increasing awareness of genetic toxicology testing in various products.
  • By application,the pharmaceutical and biotechnology segment held the largest revenue share of 44.9% in 2023.
  • By product, the service segment captured the largest revenue share of 52.1% in 2023. This is attributed to several factors such as the increasing demand for outsourced services, the complexity of testing procedures, and the need for specialized expertise.
  • By Assay,the comet assay segment dominated the market in 2023. The comet assay, also known as single-cell gel electrophoresis assay, is widely used for assessing DNA damage, it can detect a broad range of DNA damage, including single-strand breaks, double-strand breaks and incomplete repair sites.
  • The North America genetic toxicology testing market dominated the global market with a revenue share of 40.1% in 2023. The regional dominance can be attributed to increasing drug development with strong investments in pipelines.
  • Asia Pacific is projected to expand at the fastest CAGR over the forecast period, due to developments by countries such as Japan and India in tightening the regulations on testing of novel food and drug development.

Table of Contents

Chapter 1. Methodology and Scope

  • 1.1. Market Segmentation and Scope
  • 1.2. Market Definitions
  • 1.3. Research Methodology
    • 1.3.1. Information Procurement
    • 1.3.2. Information or Data Analysis
    • 1.3.3. Market Formulation & Data Visualization
    • 1.3.4. Data Validation & Publishing
  • 1.4. Research Scope and Assumptions
    • 1.4.1. List of Data Sources

Chapter 2. Executive Summary

  • 2.1. Market Outlook
  • 2.2. Segment Outlook
  • 2.3. Competitive Insights

Chapter 3. Genetic Toxicology Testing Market Variables, Trends, & Scope

  • 3.1. Market Introduction/Lineage Outlook
  • 3.2. Market Size and Growth Prospects (USD Million)
  • 3.3. Market Dynamics
    • 3.3.1. Market Drivers Analysis
    • 3.3.2. Market Restraints Analysis
  • 3.4. Genetic Toxicology Testing Market Analysis Tools
    • 3.4.1. Porter's Analysis
      • 3.4.1.1. Bargaining power of the suppliers
      • 3.4.1.2. Bargaining power of the buyers
      • 3.4.1.3. Threats of substitution
      • 3.4.1.4. Threats from new entrants
      • 3.4.1.5. Competitive rivalry
    • 3.4.2. PESTEL Analysis
      • 3.4.2.1. Political landscape
      • 3.4.2.2. Economic and Social landscape
      • 3.4.2.3. Technological landscape
      • 3.4.2.4. Environmental landscape
      • 3.4.2.5. Legal landscape

Chapter 4. Genetic Toxicology Testing Market: Product Estimates & Trend Analysis

  • 4.1. Segment Dashboard
  • 4.2. Genetic Toxicology Testing Market: Product Movement Analysis, USD Million, 2023 & 2030
  • 4.3. Reagents & Consumables
    • 4.3.1. Reagents & Consumables Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 4.4. Assays Kit
    • 4.4.1. Assays Kit Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 4.5. Services
    • 4.5.1. Services Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)

Chapter 5. Genetic Toxicology Testing Market: Type Estimates & Trend Analysis

  • 5.1. Segment Dashboard
  • 5.2. Genetic Toxicology Testing Market: Type Movement Analysis, USD Million, 2023 & 2030
  • 5.3. In vitro
    • 5.3.1. In vitro Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 5.4. In vivo
    • 5.4.1. In vivo Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)

Chapter 6. Genetic Toxicology Testing Market: Assay Estimates & Trend Analysis

  • 6.1. Segment Dashboard
  • 6.2. Genetic Toxicology Testing Market: Assay Movement Analysis, USD Million, 2023 & 2030
  • 6.3. Comet Assay
    • 6.3.1. Comet Assay Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 6.4. Micronucleus Assay
    • 6.4.1. Micronucleus Assay Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 6.5. Chromosomal Aberration Test
    • 6.5.1. Chromosomal Aberration Test Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 6.6. Genetic Mutation Test
    • 6.6.1. Genetic Mutation Test Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 6.7. Others
    • 6.7.1. Others Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)

Chapter 7. Genetic Toxicology Testing Market: Application Estimates & Trend Analysis

  • 7.1. Segment Dashboard
  • 7.2. Genetic Toxicology Testing Market: Application Movement Analysis, USD Million, 2023 & 2030
  • 7.3. Pharmaceutical & biotechnology
    • 7.3.1. Pharmaceutical & biotechnology Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.4. Food Industry
    • 7.4.1. Food Industry Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.5. Cosmetics Industry
    • 7.5.1. Cosmetics Industry Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.6. Other
    • 7.6.1. Other Market Revenue Estimates and Forecasts, 2018 - 2030 (USD Million)

Chapter 8. Genetic Toxicology Testing Market: Regional Estimates & Trend Analysis

  • 8.1. Genetic Toxicology Testing Market Share, By Region, 2023 & 2030, USD Million
  • 8.2. North America
    • 8.2.1. North America Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.2.2. U.S.
      • 8.2.2.1. U.S. Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.2.3. Canada
      • 8.2.3.1. Canada Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.2.4. Mexico
      • 8.2.4.1. Mexico Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.3. Europe
    • 8.3.1. Europe Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.3.2. UK.
      • 8.3.2.1. UK Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.3.3. Germany
      • 8.3.3.1. Germany Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.3.4. France
      • 8.3.4.1. France Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.3.5. Italy
      • 8.3.5.1. Italy Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.3.6. Spain
      • 8.3.6.1. Spain Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.3.7. Denmark
      • 8.3.7.1. Denmark Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.3.8. Sweden
      • 8.3.8.1. Sweden Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.3.9. Norway
      • 8.3.9.1. Norway Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.4. Asia Pacific
    • 8.4.1. Asia Pacific Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.4.2. Japan
      • 8.4.2.1. Japan Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.4.3. China
      • 8.4.3.1. China Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.4.4. India
      • 8.4.4.1. India Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.4.5. Australia
      • 8.4.5.1. Australia Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.4.6. South Korea
      • 8.4.6.1. South Korea Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.4.7. Thailand
      • 8.4.7.1. Thailand Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.5. Latin America
    • 8.5.1. Latin America Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.5.2. Brazil
      • 8.5.2.1. Brazil Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.5.3. Argentina
      • 8.5.3.1. Argentina Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 8.6. Middle East and Africa
    • 8.6.1. Middle East and Africa Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.6.2. South Africa
      • 8.6.2.1. South Africa Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.6.3. Saudi Arabia
      • 8.6.3.1. Saudi Arabia Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.6.4. UAE
      • 8.6.4.1. UAE Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)
    • 8.6.5. Kuwait
      • 8.6.5.1. Kuwait Genetic Toxicology Testing Market Estimates and Forecasts, 2018 - 2030 (USD Million)

Chapter 9. Competitive Landscape

  • 9.1. Recent Developments & Impact Analysis by Key Market Participants
  • 9.2. Company Categorization
  • 9.3. Company Heat Map Analysis
  • 9.4. Company Profiles
    • 9.4.1. Thermo Fisher Scientific, Inc.
      • 9.4.1.1. Participant's Overview
      • 9.4.1.2. Financial Performance
      • 9.4.1.3. Product Benchmarking
      • 9.4.1.4. Recent Developments/ Strategic Initiatives
    • 9.4.2. Charles River Laboratories
      • 9.4.2.1. Participant's Overview
      • 9.4.2.2. Financial Performance
      • 9.4.2.3. Product Benchmarking
      • 9.4.2.4. Recent Developments/ Strategic Initiatives
    • 9.4.3. Laboratory Corporation of America Holdings
      • 9.4.3.1. Participant's Overview
      • 9.4.3.2. Financial Performance
      • 9.4.3.3. Product Benchmarking
      • 9.4.3.4. Recent Developments/ Strategic Initiatives
    • 9.4.4. Eurofins Scientific
      • 9.4.4.1. Participant's Overview
      • 9.4.4.2. Financial Performance
      • 9.4.4.3. Product Benchmarking
      • 9.4.4.4. Recent Developments/ Strategic Initiatives
    • 9.4.5. Jubilant Ingrevia Limited.
      • 9.4.5.1. Participant's Overview
      • 9.4.5.2. Financial Performance
      • 9.4.5.3. Product Benchmarking
      • 9.4.5.4. Recent Developments/ Strategic Initiatives
    • 9.4.6. Syngene International Limited
      • 9.4.6.1. Participant's Overview
      • 9.4.6.2. Financial Performance
      • 9.4.6.3. Product Benchmarking
      • 9.4.6.4. Recent Developments/ Strategic Initiatives
    • 9.4.7. Gentronix, Inotiv
      • 9.4.7.1. Participant's Overview
      • 9.4.7.2. Financial Performance
      • 9.4.7.3. Product Benchmarking
      • 9.4.7.4. Recent Developments/ Strategic Initiatives
    • 9.4.8. Creative Bioarray
      • 9.4.8.1. Participant's Overview
      • 9.4.8.2. Financial Performance
      • 9.4.8.3. Product Benchmarking
      • 9.4.8.4. Recent Developments/ Strategic Initiatives
    • 9.4.9. MB Research Laboratories
      • 9.4.9.1. Participant's Overview
      • 9.4.9.2. Financial Performance
      • 9.4.9.3. Product Benchmarking
      • 9.4.9.4. Recent Developments/ Strategic Initiatives