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市场调查报告书
商品编码
1654380
美国医药市场规模、份额和趋势分析报告:按分子、产品类型、给药途径、疾病、年龄层、分销管道、细分预测,2025-2030 年U.S. Pharmaceutical Market Size, Share & Trends Analysis Report By Molecule, By Product, By Type, By Route Of Administration, By Disease, By Age Group, By Distribution Channel, And Segment Forecasts, 2025 - 2030 |
预计 2024 年美国医药市场规模为 6,343.2 亿美元,到 2030 年将达到 8,839.7 亿美元,2025 年至 2030 年的复合年增长率为 5.72%。这种增长是由于慢性病患病率上升、老龄人口增长、政府机构增加医疗保健支出以及普遍努力提高药品的可负担性和可获得性。
由于治疗方法的进步和强大的产品平臺,美国製药业正在经历强劲增长。标靶治疗、生技药品和个人化医疗的发展正在重塑治疗模式,并为癌症、自体免疫和遗传性疾病等复杂疾病提供更有效的解决方案。基因疗法和基于 RNA 的疗法正在获得 FDA核准,例如治疗遗传性视网膜疾病和某些癌症,有助于推动产业发展。用于治疗某些癌症的CAR-T细胞疗法等尖端药物的核准表明市场对精准医疗的关注度日益提高,为治疗以前无法治癒的疾病带来了希望。显着的进展包括免疫肿瘤疗法的持续进步,重新定义了癌症治疗。
在美国医药市场,GLP-1受体促效剂及GLP-1/GIP双重促效剂的突破性临床结果为肥胖治疗树立了新的标准。 GLP-1受体促效剂和GLP-1/GIP双重促效剂作为将带来前所未有的临床效果的突破性治疗方法而备受关注。这些药物,包括Semaglutide和替泽帕肽,已被证明可以使体重减轻高达 25%,远远超过先前只能达到 7% 左右减重效果的药物类别。这项突破重塑了患者和医疗保健提供者的肥胖治疗模式,为长期难以控制的疾病提供了可行的医疗解决方案。加上数位健康工具的进步,这些治疗现在已成为将药物治疗与技术、行为指导和个人化介入相结合的综合护理模式的一部分。这种综合方法不仅能解决肥胖问题,还能改善患者的整体治疗效果,为克服美国重大公共卫生挑战指明了方向。
美国医药品研究开发费用是市场成长的重要驱动力,该领域不断投资于发现和开发新的治疗方法。 2023年,美国製药公司在研发上的投入将超过800亿美元,而且这个数字每年都在增加。强生、默克、礼来等大公司认识到开发创新药物以应对人口老化和慢性病增加的重要性,并将公司收益的很大一部分用于研发。
如此高水准的投资正在推动肿瘤学、免疫学和罕见疾病等多个领域的突破性治疗方法的发现。根据牛津学术杂誌的报导,到2023年,美国的药品支出将增加13.6%,达到7,225亿美元。这一增长是由利用率增加 6.5%、新药增加 4.2% 以及价格上涨 2.9% 所推动的。 2023 年最畅销的药物是Semaglutide,其次是Adalimumab和Apixaban。此外,到 2023 年,非联邦医院的药品支出预计将下降 1.1% 至 371 亿美元,而诊所的药品支出将增加 15.0% 至 1,357 亿美元。诊所的成长是由利用率的提高所推动的,仅受到新产品和价格变化的轻微影响。对于非联邦医院,利用率降低导致支出降低,但新药和价格的影响很小。预计 2024 年将推出的几种新药将继续推动支出,尤其是在专科、内分泌和肿瘤治疗领域。
新型创新药物不断涌入市场也是美国医药市场发展的主要动力之一。随着患者和医疗保健提供者越来越意识到新疗法的有效性,对具有更好结果和更少副作用的最先进治疗的需求也日益增加。特别是生技药品、基因治疗、免疫治疗对癌症、自体免疫疾病等的应用日益广泛。例如,单株抗体(如用于免疫肿瘤学的抗体)的快速应用已经改变了治疗格局,市场领导者 Keytruda 和Opdivo 的与前一年同期比较实现了令人印象深刻的成长。近日,2024年9月,API研发中心接受了1,400万美元的战略资金,旨在加强美国製药独立性。这笔资金将支持美国关键活性药物原料药(API) 製造能力的发展,提高供应链的弹性并减少对海外来源的依赖。这项倡议符合加强国内生产、提高国家安全和确保持续获得基本药物的努力。
然而,主要药物的专利到期是美国製药业发展的一大限制因素。当专利到期时,学名药往往会进入市场,导致品牌药销售量急剧下降。例如,2023年1月,艾伯维的重磅药物Humira(Adalimumab)的专利将到期,该药物年销售额超过200亿美元,为生物仿製药的竞争打开了大门。从品牌药物转变为学名药的转变将减少原产公司的市场占有率,从而严重影响其收益来源。整体市场动态也将受到学名药定价压力的影响,迫使原产公司降低价格或寻找新的市场利基。这种转变在生技药品市场尤为明显,其中Enbrel和Herceptin等主要产品的专利已到期,为更便宜的替代品铺平了道路。
The U.S. pharmaceutical market size was estimated at USD 634.32 billion in 2024 and is expected to grow at a CAGR of 5.72% from 2025 to 2030, to reach an estimated value of USD 883.97 billion by 2030. This growth can be attributed to the rising prevalence of chronic diseases, increasing geriatric population, growing healthcare expenditure by government organizations, and extensive efforts to improve the affordability & accessibility of pharmaceuticals.
The U.S. pharmaceutical industry has experienced significant growth due to advancements in therapeutics and a robust product pipeline. The development of targeted therapies, biologics, and personalized medicine has reshaped treatment model, offering more effective solutions for complex conditions such as cancer, autoimmune diseases, and genetic disorders. Gene therapies and RNA-based treatments, like those for inherited retinal diseases and certain types of cancers, have gained FDA approvals, contributing to the industry's momentum. The approval of cutting-edge drugs such as CAR-T cell therapies for certain cancers exemplifies the market's growing focus on precision medicine, offering hope for previously untreatable conditions. A notable advancement is the continued progression in immuno-oncology treatments, which are redefining cancer care.
In the U.S. market for pharmaceuticals, the transformative clinical outcomes of GLP-1 receptor agonists and GLP-1/GIP dual agonists, have set a new benchmark for obesity treatment. As they are emerged as transformative therapies, delivering unprecedented clinical results. These medications, such as semaglutide and tirzepatide, have demonstrated weight loss of up to 25%, significantly outperforming earlier drug classes, which achieved only about 7% weight reduction. This breakthrough has reshaped the obesity treatment paradigm for both patients and providers, offering a viable medical solution to a condition long viewed as difficult to manage. Coupled with advances in digital health tools, these therapies are part of integrated care models that combine pharmacological treatments with technology, behavioral coaching, and personalized interventions. This comprehensive approach not only addresses obesity but also improves overall patient outcomes, presenting a credible pathway to overcoming a major public health challenge in the U.S.
Pharmaceutical R&D spending in the U.S. has been a pivotal driver of market growth, with the sector continuously investing in the discovery and development of new therapies. In 2023, pharmaceutical companies in the U.S. spent over USD 80 billion on R&D, a figure that continues to rise annually. Major companies like Johnson & Johnson, Merck, and Eli Lilly have earmarked significant portions of their revenues to R&D, recognizing the importance of developing innovative drugs to meet the demands of an aging population and the increasing prevalence of chronic diseases.
This high level of investment fuels the discovery of breakthrough therapies across various segments, including oncology, immunology, and rare diseases. According to an article by oxford Academic, in 2023, U.S. pharmaceutical spending rose by 13.6% to reach USD 722.5 billion. This increase was driven by a 6.5% rise in utilization, a 4.2% boost from new drugs, and a 2.9% uptick in prices. The top-selling drug of 2023 was semaglutide, followed by adalimumab and apixaban. Furthermore, In 2023, drug spending in nonfederal hospitals decreased by 1.1%, totaling USD 37.1 billion, while expenditures in clinics increased by 15.0% to USD 135.7 billion. Clinic growth was driven by higher utilization, with a minor impact from new products and price changes. In nonfederal hospitals, lower utilization led to reduced spending, while new drugs and prices had a modest influence. Several new drugs expected in 2024, especially in specialty, endocrine, and cancer treatments, will continue to drive spending.
The growing market adoption of innovative and modern medicines is another key driver of the U.S. pharmaceutical market. As patients and healthcare providers become more aware of the effectiveness of new treatments, there is an increasing demand for cutting-edge therapies that offer better outcomes and fewer side effects. The uptake of biologics, gene therapies, and immunotherapies in oncology, autoimmune diseases, and other areas has been particularly notable. For example, the rapid adoption of monoclonal antibodies, such as those used in immuno-oncology, has transformed the treatment landscape, with market leaders like Keytruda and Opdivo showing impressive year-on-year sales growth. Recently, in September 2024, the API Innovation Center received USD 14 million in strategic funding aimed at strengthening U.S. pharmaceutical independence. The funding will support the development of critical Active Pharmaceutical Ingredients (API) manufacturing capabilities within the U.S., enhancing resilience in the supply chain and reducing reliance on foreign sources. This initiative aligns with efforts to bolster domestic production, improve national security, and ensure consistent access to essential medicines.
However, Patent expiration of key pharmaceutical drugs has emerged as a significant restraint for the growth of the U.S. pharmaceutical industry. Once patents expire, generic versions of these drugs can enter the market, often leading to a sharp decline in sales for the original branded drugs. For instance, in January 2023, the patent for AbbVie's blockbuster drug Humira (adalimumab), which generated over USD 20 billion in annual sales, expired, allowing biosimilars to compete. The shift from branded to generic drugs reduces the market share of originator companies and significantly impacts their revenue streams. The overall market dynamics are also affected by the pricing pressure brought on by these generics, forcing branded companies to reduce prices or find new market niches. This change is particularly evident in the biologics market, where patents for key products like Enbrel and Herceptin have expired, opening the door for cheaper alternatives.
U.S. Pharmaceutical Market Report Segmentation
This report forecasts revenue growth and provides an analysis on the latest trends in each of the sub-segments from 2018 to 2030. For the purpose of this report, Grand View Research has segmented the U.S. pharmaceutical market report based on molecule, product, type, disease, route of administration, age group, and distribution channel: