美国聚合物药物研发外包市场规模、份额、趋势分析报告：按工作流程、服务、治疗类别、最终用途、细分市场预测，2025-2033

市场规模与趋势：

预计 2024 年美国聚合物药物发现外包市场规模将达到 9.686 亿美元，预计 2025 年至 2033 年的复合年增长率为 9.20%。

由于製药业加速向创新生技药品转变以及生技药品产品线不断扩大，市场正在经历强劲增长，因为单株抗体、双特异性抗体、融合蛋白和抗体药物复合体（ADC）等大分子在治疗各种疾病（包括癌症、自体免疫疾病和慢性疾病）方面的需求持续旺盛。

在美国，製药和生技公司越来越多地转向委外研发机构(CRO)，以加快药物研发流程、降低成本并获得专业知识。这些外包伙伴关係提供各种服务，包括先导化合物、候选药物优化、生物学服务和临床前开发，并正在朝向基于平台的整合式外包模式迈进。此外，对生技药品（尤其是融合蛋白和工程抗体等新一代製剂）日益增长的需求，正促使公司将研发业务外包，以缩短週期并管理复杂性。

以精准筛检、生物目标和体外功能分析为重点的外包可增强分子优化和早期可製造性评估。罕见疾病和个人化免疫疗法等利基治疗领域的兴起进一步推动了对高度客製化药物发现解决方案的需求。此外，透过单一合作伙伴网路整合发现、临床前和早期开发活动的外包模式预计将在整个预估期内推动市场发展。在美国，对人工智慧标靶发现、微流体筛检、低温电子显微镜和云端原生平台等技术进步的关注正在成为跨不同开发计划的生物製药药物发现的战略推动因素，进一步推动市场成长。

目录

第一章调查方法与范围

第二章执行摘要

第三章美国聚合物药物发现外包市场变数、趋势与范围

• 市场展望
  • 母市场展望
  • 相关/支持市场展望
• 市场动态
  • 市场驱动因素分析
  • 市场限制因素分析
• 技术格局
• 定价模式分析
• 市场分析工具
  • 波特五力分析
  • PESTEL 与 SWOT 分析

第四章美国聚合物药物发现外包市场：工作流程评估与趋势分析

• 美国聚合物药物研发外包市场（依工作流程）：细分仪表板
• 美国聚合物药物研发外包市场（依工作流程）：差异分析
• 按工作流程，2021-2033 年
• 目标识别与筛检
• 目标检验和功能资讯科学
• 潜在客户资格审查和候选人优化
• 临床前开发
• 其他的

第五章美国聚合物药物发现外包市场：服务评估与趋势分析

• 美国聚合物药物研发外包市场（按服务）：细分仪表板
• 美国聚合物药物研发外包市场（按服务）：变化分析
• 按服务划分，2021-2033 年
• 化学服务
• 生物服务

第六章美国聚合物药物研发外包市场：治疗药物细分市场的估价与趋势分析

• 美国聚合物药物研发外包市场（依治疗领域）：细分仪表板
• 美国聚合物药物研发外包市场（依治疗类别）：波动分析
• 2021-2033 年各治疗类别药物
• 呼吸系统
• 疼痛和麻醉
• 肿瘤学
• 眼科
• 血液学
• 心血管系统
• 内分泌
• 胃肠道
• 免疫调节
• 抗感染
• 中枢神经系统
• 皮肤科
• 泌尿生殖系统

第七章美国聚合物药物发现外包市场：最终用途估计与趋势分析

• 美国聚合物药物研发外包市场（依最终用途）：细分仪表板
• 美国聚合物药物研发外包市场（依最终用途）：差异分析
• 按应用，2021-2033 年
• 製药和生物技术公司
• 学术机构

第八章 竞争态势

• 市场参与企业分类
  • 市场领导者
  • 新兴企业
• 2024 年公司市场占有率/估值分析
• 公司简介
  • Charles River Laboratories International, Inc.
  • Laboratory Corporation of America Holdings
  • Thermo Fisher Scientific, Inc.
  • GenScript Biotech Corporation
  • Syngene International Limited
  • Dalton Pharma Services
  • Eurofins Scientific SE
  • TCG Lifesciences Pvt Ltd.
  • Evotec SE
  • WuXi AppTec
  • Jubilant Biosys Limited
  • Pharmaron Beijing Co., Ltd.

第九章 主要建议

Market Size & Trends:

The U.S. large molecule drug discovery outsourcing market size was estimated at USD 968.60 million in 2024 and is projected to grow at a CAGR of 9.20% from 2025 to 2033. The market is experiencing robust growth, driven by the accelerating shift in the pharmaceutical industry towards innovative biologics and expanding pipeline biologics. Besides, large molecules, including monoclonal antibodies, bispecific, fusion proteins, and antibody-drug conjugates (ADCs), continue to witness rising demand to treat various diseases, including cancer, autoimmune disorders, and chronic conditions.

In the U.S., pharmaceutical and biotechnology companies are increasingly turning to contract research organizations (CROs) to accelerate the discovery process, lower costs, and gain access to specialized technologies. These outsourcing partnerships provide various services, including lead identification, candidate optimization, biology services, and preclinical development, with a shift toward integrated, platform-based outsourcing models. Moreover, rising demand for biologics, particularly next-generation formats such as fusion proteins and engineered antibodies, has led companies to outsource discovery tasks to reduce cycle times and manage complexity.

Outsourcing the company's focus on precision screening, target biology, and in vitro functional analysis enhances molecular optimization and early manufacturability assessments. The rise of niche therapeutic areas, such as rare diseases and personalized immunotherapies, further increases the need for highly customized discovery solutions. Besides, integrated outsourcing models that combine discovery, preclinical, and early development activities through a single partner network are expected to drive the market over the estimated period. With a focus on technological advancements in the U.S., including AI-driven target discovery, microfluidics-based screening, cryo-electron microscopy, and cloud-native platforms, outsourcing for extensive molecule drug discovery is becoming a strategic enabler of biologic drug discovery across diverse development programs, which further supports the market growth.

U.S. Large Molecule Drug Discovery Outsourcing Market Report Segmentation

This report forecasts revenue growth at the country level and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, Grand View Research has segmented the U.S. large molecule drug discovery outsourcing market report based on workflow, service, therapeutics area, and end-use:

• Workflow Outlook (Revenue, USD Million, 2021 - 2033)
• Target Identification & Screening
• Target Validation & Functional Informatics
• Lead Identification & Candidate Optimization
• Preclinical Development
• Others
• Service Outlook (Revenue, USD Million, 2021 - 2033)
• Chemistry Services
• Biology Services
• Therapeutics Area Outlook (Revenue, USD Million, 2021 - 2033)
• Respiratory system
• Pain and Anesthesia
• Oncology
• Ophthalmology
• Hematology
• End-use Outlook (Revenue, USD Million, 2021 - 2033)
• Pharmaceutical & Biotechnology companies
• Academic Institutes

Table of Contents

Chapter 1. Research Methodology and Scope

• 1.1. Market Segmentation & Scope
• 1.2. Market Definitions
• 1.3. Research Methodology
• 1.4. Information Procurement
  • 1.4.1. Purchased Database
  • 1.4.2. GVR's Internal Database
  • 1.4.3. Secondary Sources
  • 1.4.4. Primary Research
• 1.5. Information Or Data Analysis
  • 1.5.1. Data Analysis Models
• 1.6. Market Formulation & Validation
• 1.7. Model Details
  • 1.7.1. Commodity Flow Analysis
  • 1.7.2. Parent Market Analysis
• 1.8. List Of Secondary Sources
• 1.9. List Of Abbreviations
• 1.10. Objectives

Chapter 2. Executive Summary

• 2.1. Market Outlook
• 2.2. Segment Outlook
• 2.3. Competitive Insights

Chapter 3. U.S. Large Molecule Drug Discovery Outsourcing Market Variables, Trends & Scope

• 3.1. Market Lineage Outlook
  • 3.1.1. Parent Market Outlook
  • 3.1.2. Related/Ancillary Market Outlook
• 3.2. Market Dynamics
  • 3.2.1. Market Driver Analysis
  • 3.2.2. Market Restraint Analysis
• 3.3. Technology Landscape
• 3.4. Pricing Model Analysis
• 3.5. Market Analysis Tools
  • 3.5.1. Porter's Five Force Analysis
  • 3.5.2. PESTEL by SWOT Analysis

Chapter 4. U.S. Large Molecule Drug Discovery Outsourcing Market: Workflow Estimates & Trend Analysis

• 4.1. U.S. Large Molecule Drug Discovery Outsourcing Market, By Workflow: Segment Dashboard
• 4.2. U.S. Large Molecule Drug Discovery Outsourcing Market, By Workflow: Movement Analysis
• 4.3. U.S. Large Molecule Drug Discovery Outsourcing Market Estimates & Forecasts, By Workflow, 2021-2033 (USD Million)
• 4.4. Target Identification & Screening
  • 4.4.1. Target Identification & Screening Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 4.5. Target Validation & Functional Informatics
  • 4.5.1. Target Validation & Functional Informatics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 4.6. Lead Identification & Candidate Optimization
  • 4.6.1. Lead Identification & Candidate Optimization Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 4.7. Preclinical Development
  • 4.7.1. Preclinical Development Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 4.8. Others
  • 4.8.1. Others Market Estimates and Forecasts, 2021 - 2033 (USD Million)

Chapter 5. U.S. Large Molecule Drug Discovery Outsourcing Market: Service Estimates & Trend Analysis

• 5.1. U.S. Large Molecule Drug Discovery Outsourcing Market, By Service: Segment Dashboard
• 5.2. U.S. Large Molecule Drug Discovery Outsourcing Market, By Service: Movement Analysis
• 5.3. U.S. Large Molecule Drug Discovery Outsourcing Market Estimates & Forecasts, By Service, 2021-2033 (USD Million)
• 5.4. Chemistry Services
  • 5.4.1. Chemistry Services Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 5.5. Biology Services
  • 5.5.1. Biology Services Market Estimates and Forecasts, 2021 - 2033 (USD Million)

Chapter 6. U.S. Large Molecule Drug Discovery Outsourcing Market: Therapeutics Area Estimates & Trend Analysis

• 6.1. U.S. Large Molecule Drug Discovery Outsourcing Market, By Therapeutics Area: Segment Dashboard
• 6.2. U.S. Large Molecule Drug Discovery Outsourcing Market, By Therapeutics Area: Movement Analysis
• 6.3. U.S. Large Molecule Drug Discovery Outsourcing Market Estimates & Forecasts, By Therapeutics Area, 2021-2033 (USD Million)
• 6.4. Respiratory system
  • 6.4.1. Respiratory System Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 6.5. Pain and Anesthesia
  • 6.5.1. Pain and Anesthesia Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 6.6. Oncology
  • 6.6.1. Oncology Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 6.7. Ophthalmology
  • 6.7.1. Ophthalmology Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 6.8. Hematology
  • 6.8.1. Hematology Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 6.9. Cardiovascular
  • 6.9.1. Cardiovascular Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 6.10. Endocrine
  • 6.10.1. Endocrine Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 6.11. Gastrointestinal
  • 6.11.1. Gastrointestinal Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 6.12. Immunomodulation
  • 6.12.1. Immunomodulation Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 6.13. Anti-infective
  • 6.13.1. Anti-infective Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 6.14. Central Nervous System
  • 6.14.1. Central Nervous System Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 6.15. Dermatology
  • 6.15.1. Dermatology Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 6.16. Genitourinary System
  • 6.16.1. Genitourinary System Market Estimates and Forecasts, 2021 - 2033 (USD Million)

Chapter 7. U.S. Large Molecule Drug Discovery Outsourcing Market: End Use Estimates & Trend Analysis

• 7.1. U.S. Large Molecule Drug Discovery Outsourcing Market, By End Use: Segment Dashboard
• 7.2. U.S. Large Molecule Drug Discovery Outsourcing Market, By End Use: Movement Analysis
• 7.3. U.S. Large Molecule Drug Discovery Outsourcing Market Estimates & Forecasts, By End Use, 2021-2033 (USD Million)
• 7.4. Pharmaceutical & Biotechnology companies
  • 7.4.1. Pharmaceutical & Biotechnology companies Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 7.5. Academic Institutes
  • 7.5.1. Academic Institutes Market Estimates and Forecasts, 2021 - 2033 (USD Million)

Chapter 8. Competitive Landscape

• 8.1. Market Participant Categorization
  • 8.1.1. Market Leaders
  • 8.1.2. Emerging Players
• 8.2. Company Market Share/Assessment Analysis, 2024
• 8.3. Company Profiles
  • 8.3.1. Charles River Laboratories International, Inc.
    • 8.3.1.1. Company Overview
    • 8.3.1.2. Financial Performance
    • 8.3.1.3. Service Benchmarking
    • 8.3.1.4. Strategic Initiatives
  • 8.3.2. Laboratory Corporation of America Holdings
    • 8.3.2.1. Company Overview
    • 8.3.2.2. Financial Performance
    • 8.3.2.3. Service Benchmarking
    • 8.3.2.4. Strategic Initiatives
  • 8.3.3. Thermo Fisher Scientific, Inc.
    • 8.3.3.1. Company Overview
    • 8.3.3.2. Financial Performance
    • 8.3.3.3. Service Benchmarking
    • 8.3.3.4. Strategic Initiatives
  • 8.3.4. GenScript Biotech Corporation
    • 8.3.4.1. Company Overview
    • 8.3.4.2. Financial Performance
    • 8.3.4.3. Service Benchmarking
    • 8.3.4.4. Strategic Initiatives
  • 8.3.5. Syngene International Limited
    • 8.3.5.1. Company Overview
    • 8.3.5.2. Financial Performance
    • 8.3.5.3. Service Benchmarking
    • 8.3.5.4. Strategic Initiatives
  • 8.3.6. Dalton Pharma Services
    • 8.3.6.1. Company Overview
    • 8.3.6.2. Financial Performance
    • 8.3.6.3. Service Benchmarking
    • 8.3.6.4. Strategic Initiatives
  • 8.3.7. Eurofins Scientific SE
    • 8.3.7.1. Company Overview
    • 8.3.7.2. Financial Performance
    • 8.3.7.3. Service Benchmarking
    • 8.3.7.4. Strategic Initiatives
  • 8.3.8. TCG Lifesciences Pvt Ltd.
    • 8.3.8.1. Company Overview
    • 8.3.8.2. Financial Performance
    • 8.3.8.3. Service Benchmarking
    • 8.3.8.4. Strategic Initiatives
  • 8.3.9. Evotec SE
    • 8.3.9.1. Company Overview
    • 8.3.9.2. Financial Performance
    • 8.3.9.3. Service Benchmarking
    • 8.3.9.4. Strategic Initiatives
  • 8.3.10. WuXi AppTec
    • 8.3.10.1. Company Overview
    • 8.3.10.2. Financial Performance
    • 8.3.10.3. Service Benchmarking
    • 8.3.10.4. Strategic Initiatives
  • 8.3.11. Jubilant Biosys Limited
    • 8.3.11.1. Company Overview
    • 8.3.11.2. Financial Performance
    • 8.3.11.3. Service Benchmarking
    • 8.3.11.4. Strategic Initiatives
  • 8.3.12. Pharmaron Beijing Co., Ltd.
    • 8.3.12.1. Company Overview
    • 8.3.12.2. Financial Performance
    • 8.3.12.3. Service Benchmarking
    • 8.3.12.4. Strategic Initiatives

Chapter 9 Key Recommendations

List of Tables

• Table 1. List of Tables
• Table 2. List of Secondary Sources
• Table 3. List of Abbreviations
• Table 4. U.S. Large Molecule Drug Discovery Outsourcing Market Estimates and Forecasts, by Workflow, 2021 - 2033 (USD Million)
• Table 5. U.S. Large Molecule Drug Discovery Outsourcing Market Estimates and Forecasts, by Service, 2021 - 2033 (USD Million)
• Table 6. U.S. Large Molecule Drug Discovery Outsourcing Market Estimates and Forecasts, by Therapeutics Area, 2021 - 2033 (USD Million)
• Table 7. U.S. Large Molecule Drug Discovery Outsourcing Market Estimates and Forecasts, by End Use, 2021 - 2033 (USD Million)

List of Figures

• Fig. 1 Market research process
• Fig. 2 Information procurement
• Fig. 3 Primary research pattern
• Fig. 4 Market research approaches
• Fig. 5 Market formulation & validation
• Fig. 6 Commodity flow analysis
• Fig. 7 Value-chain-based sizing & forecasting
• Fig. 8 QFD model sizing & forecasting
• Fig. 9 Bottom-up approach
• Fig. 10 Market snapshot
• Fig. 11 Segment snapshot 1
• Fig. 12 Segment snapshot 2
• Fig. 13 Competitive landscape snapshot
• Fig. 14 Parent market outlook, 2024 (USD Billion)
• Fig. 15 Ancillary market outlook, 2024 (USD Billion)
• Fig. 16 U.S. Large Molecule Drug Discovery Outsourcing Market Dynamics
• Fig. 17 Porter's five forces analysis
• Fig. 18 PESTEL analysis
• Fig. 19 U.S. Large Molecule Drug Discovery Outsourcing Market: Workflow outlook and key takeaways
• Fig. 20 U.S. Large Molecule Drug Discovery Outsourcing Market: Workflow movement analysis
• Fig. 21 Target Identification & Screening Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 22 Target Validation & Functional Informatics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 23 Lead Identification & Candidate Optimization Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 24 Preclinical Development Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 25 Other Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 26 U.S. Large Molecule Drug Discovery Outsourcing Market: Service outlook and key takeaways
• Fig. 27 U.S. Large Molecule Drug Discovery Outsourcing Market: Service movement analysis
• Fig. 28 Chemistry Services Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 29 Biology Services Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 30 U.S. Large Molecule Drug Discovery Outsourcing Market: Therapeutics Area outlook and key takeaways
• Fig. 31 U.S. Large Molecule Drug Discovery Outsourcing Market: Therapeutics Area movement analysis
• Fig. 32 Respiratory system Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 33 Pain and Anesthesia Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 34 Oncology Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 35 Ophthalmology Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 36 Hematology Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 37 Cardiovascular Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 38 Endocrine Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 39 Gastrointestinal Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 40 Immunomodulation Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 41 Anti-infective Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 42 Central Nervous System Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 43 Dermatology Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 44 Genitourinary System Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 45 U.S. Large Molecule Drug Discovery Outsourcing Market: End Use outlook and key takeaways
• Fig. 46 U.S. Large Molecule Drug Discovery Outsourcing Market: End Use movement analysis
• Fig. 47 Pharmaceutical & Biotechnology companies Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 48 Academic Institutes Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 49 Key company categorization
• Fig. 50 Service heat map analysis
• Fig. 51 Strategic framework