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市场调查报告书
商品编码
1888749

美国硬膜密封剂和纤维蛋白黏合剂市场规模、份额和趋势分析报告（按 CPT 手术代码、最终用途和细分市场预测，2025-2035 年）

U.S. Dural Sealants And Fibrin Glues Market Size, Share & Trends Analysis Report By CPT Procedure Code (61510 / 61512, 61320 - 61323, 61518, 62140 / 62141, 63707, 63709, 63710), By End Use, And Segment Forecasts, 2025 - 2035
出版日期: | 出版商: Grand View Research | 英文 125 Pages | 商品交期: 2-10个工作天内

价格

市场规模与趋势：

预计到 2024 年，美国杜拉尔密封剂和纤维蛋白黏合剂市场规模将达到 65.7 亿美元，到 2035 年将达到 109.9 亿美元。

预计从 2025 年到 2035 年，该行业将以 4.78% 的复合年增长率成长。这一增长是由神经外科和脊椎手术数量的增加所驱动的，特别是复杂的颅内手术、后颅窝手术和脊椎硬膜成形术，在这些手术中，防止脑脊髓液漏至关重要。

Dykhouse 等人于 2024 年发表在《神经外科杂誌·脊柱分册》上的一项研究表明，美国脊柱手术数量持续稳定增长，从 2013 年的约 80 万例增加到 2022 年的超过 110 万例。这一增长与退化性脊椎疾病的快速增加、人口老化以及手术安全性的提高（尤其是在老年患者中）密切相关。

医院和门诊手术中心优先选择能够确保伤口水密闭合、减少术后併发症并支持以价值为导向的治疗结果的密封剂和黏合剂。聚乙二醇（PEG）基水凝胶、胶原蛋白移植物和合成密封剂等先进产品的日益普及、有利的报销政策以及不断增长的门诊手术量，都在推动市场进一步扩张。医院和手术中心优先选择能够最大限度减少脑脊髓液（CSF）漏、缩短恢復时间和降低再入院率的产品。根据美国医疗保健研究与品质署（AHRQ）统计，术后脑脊髓液漏占神经外科併发症的3%至8%，且通常需要再次手术。这些再次手术不仅每次增加约25,000至4万美元的额外费用，还会显着延长住院时间并增加感染风险。

此外，机器人辅助手术和影像导引手术（IGS）的加速普及为硬膜密封剂和纤维蛋白黏合剂在美国开闢了清晰的成长路径。随着神经外科医生和脊椎团队向精准手术平台转型，对可靠、相容于微创手术流程且能在有限手术视野内实现可预测、完全闭合的辅助产品的需求日益增长。 2025年发表于Cureus的一项科学计量学分析检验了脊椎手术中硬膜密封剂的研究趋势。结果显示，约40%的研究源自美国，且近期研究主题已从「密封剂类型」转向「临床结果、安全性、有效性和工作流程整合」。

此外，MPO杂誌2025年10月发表的一篇关于手术机器人行业的综述说明，手术平台正进入一个“新阶段”，强调软体主导的差异化、门诊手术流程的重新设计以及与辅助设备的兼容性。这些数据表明，先进的手术平台（机器人/术中介入手术）与血管内辅助技术的融合日益加深，为适用于这些环境的密封剂和黏合剂创造了巨大的需求动力。这些因素共同推动了市场成长。

目录

第一章调查方法和范围

第二章执行摘要

第三章美国杜拉尔密封剂和纤维蛋白黏合剂市场变数、趋势和范围

  • 市场体系展望
    • 母市场展望
    • 相关及辅助市场展望
  • 市场动态
  • 美国杜拉尔密封剂和纤维蛋白黏合剂市场分析工具
    • 波特分析
    • PESTEL 分析

第四章美国硬膜密封剂和纤维蛋白黏合剂市场：按CPT程序代码分類的估算和趋势分析

  • 美国硬膜密封剂和纤维蛋白黏合剂市场：按 CPT 程序代码分類的差异分析
  • 美国硬膜密封剂和纤维蛋白黏合剂市场：按 CPT 手术代码分類的展望
  • 市场规模、预测与趋势分析（2024-2035）
  • 61510/61512-开颅切除上脑室病变
  • 61320-61323-减压性颅骨切除术或减压性颅骨切除术（伴或不伴硬脑膜成形术）
  • 61518-后颅窝病变开颅手术
  • 62140/62141-颅骨成形术或硬脑膜重组
  • 63707 - 不经切除术术修復颅内或脊髓液漏
  • 63709 - 脑脊髓液漏或假性脑膜膨出切除术术修补
  • 63710-硬膜移植（脊椎）
  • 63030 -切除术/腰椎切除术，神经根减压手术
  • 63047-切除术（腰椎，1 个或多个椎体）
  • 22612/22630-后路脊椎融合手术减压术

第五章美国杜拉尔密封剂和纤维蛋白黏合剂市场：按最终用途分類的估算和趋势分析

  • 美国硬质密封剂和纤维蛋白黏合剂市场：按最终用途分類的变化分析
  • 美国硬质密封剂和纤维蛋白黏合剂市场：按最终用途分類的展望
  • 市场规模、预测与趋势分析（2024-2035）
  • 医院
  • 门诊手术中心
  • 专科诊所

第六章 竞争情势

  • 市场参与企业分类
  • 主要企业简介
    • Integra LifeSciences
    • Stryker
    • Baxter
    • Ethicon（J&J;）
    • Takeda Pharmaceutical
    • B. Braun Medical
    • Cook Medical
    • Polyganics
Product Code: GVR-4-68040-810-6

Market Size & Trends:

The U.S. dural sealants and fibrin glues market size was valued at USD 6.57 billion in 2024 and is expected to reach USD 10.99 billion by 2035, growing at a CAGR of 4.78% from 2025 to 2035. Growth is driven by increasing neurosurgical and spinal procedure volumes, particularly complex cranial, posterior fossa, and spinal duraplasty cases where cerebrospinal fluid (CSF) leak prevention is critical.

According to a 2024 study published in the Journal of Neurosurgery: Spine by Dykhouse et al., spine procedure volumes in the U.S. increased from approximately 800,000 in 2013 to over 1.1 million in 2022, representing a steady and sustained growth. This expansion is closely linked with a surge in degenerative spine disorders, aging demographics, and improved surgical safety, particularly for older patients.

Hospitals and ambulatory surgical centers prioritize sealants and glues that ensure watertight closure, reduce postoperative complications, and support value-based outcomes. The rising adoption of advanced products, such as PEG-based hydrogels, collagen grafts, and synthetic sealants, along with favorable reimbursement and increasing outpatient surgical volumes, further fuels market expansion. Hospitals and surgical centers are prioritizing products that minimize cerebrospinal fluid (CSF) leaks, shorten recovery times, and lower readmission rates. According to the Agency for Healthcare Research and Quality (AHRQ), postoperative CSF leaks account for up to 3-8% of neurosurgical complications, often requiring revision surgery. These reoperations not only elevate costs by nearly USD 25,000-USD 40,000 per case, but also significantly extend hospital stays and increase infection risk.

Moreover, the accelerating adoption of robotic-assisted and image-guided surgery (IGS) presents a clear growth pathway for dural sealants and fibrin glues in the U.S. As neurosurgeons and spine teams migrate toward precision platforms, demand rises for adjunctive products that are reliable, compatible with minimally invasive workflows, and deliver predictable watertight closure in constrained operative fields. A 2025 scientometric analysis published in Cureus reviewed the publication trends for dural sealants in spine surgery. It found that nearly 40% of research originates in the U.S., and recent research topics have shifted from "types of sealants" to "clinical outcomes, safety, efficacy, and workflow integration".

Furthermore, an industry review of surgical robotics published by MPO Magazine in October 2025 described the field entering a "new phase" where platforms emphasize software-led differentiation, outpatient redesign and compatibility with adjunct devices. These data points demonstrate a growing intersection between advanced surgical platforms (robotics/IGS) and dural adjunct technologies, creating a substantive momentum for sealants and glues optimized for these environments. These factors are collectively contributing to the growth of market.

U.S. Dural Sealants And Fibrin Glues Market Report Segmentation

This report forecasts revenue growth at the country level and analyzes the latest industry trends in each sub-segments from 2024 to 2035. For this study, Grand View Research has segmented the U.S. dural sealants and fibrin glues market report based on CPT procedure codes and end use:

  • CPT Procedure Codes Outlook (Revenue, USD Unit, 2024 - 2035)
  • 61510 / 61512 - Craniotomy for supratentorial lesion removal
  • 61320 - 61323 - Craniectomy or craniotomy, decompressive (with or without duraplasty)
  • 61518- Craniotomy for infratentorial/posterior fossa lesion
  • 62140 / 62141- Cranioplasty or dural reconstruction
  • 63707- Repair of CSF leak, cranial or spinal, without laminectomy
  • 63709 - Repair of CSF leak or pseudomeningocele with laminectomy
  • 63710- Dural graft (spinal)
  • 63030 - Laminotomy/laminectomy (lumbar), decompression of nerve root
  • 63047 - Laminectomy, >1 vertebral segment, lumbar
  • 22612 / 22630 - Posterior spinal fusion with decompression
  • End Use Outlook (Revenue, USD Unit, 2024 - 2035)
  • Hospitals
  • Ambulatory Surgical Centers
  • Specialty Clinics

Table of Contents

Chapter 1. Methodology and Scope

  • 1.1. Market Segmentation and Scope
  • 1.2. Segment Definitions
    • 1.2.1. CPT Procedure Codes
    • 1.2.2. End Use
    • 1.2.3. Estimates and forecasts timeline
  • 1.3. Research Methodology
  • 1.4. Information Procurement
    • 1.4.1. Purchased database
    • 1.4.2. GVR's internal database
    • 1.4.3. Secondary sources
    • 1.4.4. Primary research
    • 1.4.5. Details of primary research
      • 1.4.5.1. Data for primary interviews in North America
  • 1.5. Information or Data Analysis
    • 1.5.1. Data analysis models
  • 1.6. Market Formulation & Validation
  • 1.7. Model Details
    • 1.7.1. Commodity flow analysis (Model 1)
    • 1.7.2. Approach 1: Commodity flow approach
    • 1.7.3. Volume price analysis (Model 2)
    • 1.7.4. Approach 2: Volume price analysis
  • 1.8. List of Secondary Sources
  • 1.9. List of Primary Sources
  • 1.10. Objectives

Chapter 2. Executive Summary

  • 2.1. Market Outlook
  • 2.2. Segment Outlook
    • 2.2.1. CPT Procedure Codes
    • 2.2.2. End Use outlook
  • 2.3. Competitive Insights

Chapter 3. U.S. Dural Sealants and Fibrin Glues Market Variables, Trends & Scope

  • 3.1. Market Lineage Outlook
    • 3.1.1. Parent market outlook
    • 3.1.2. Related/ancillary market outlook
  • 3.2. Market Dynamics
    • 3.2.1. Market Driver Analysis
      • 3.2.1.1. Rising neurosurgical and spinal procedures
      • 3.2.1.2. Focus on patient safety and reduced reoperations
      • 3.2.1.3. Breakthrough biomaterials driving next-gen dural repair
    • 3.2.2. Market Restraint Analysis
      • 3.2.2.1. Unnecessary back surgeries limiting ethical utilization
      • 3.2.2.2. Availability of alternative techniques
  • 3.3. U.S. Dural Sealants and Fibrin Glues Market Analysis Tools
    • 3.3.1. Industry Analysis - Porter's
      • 3.3.1.1. Bargaining power of suppliers
      • 3.3.1.2. Bargaining power of buyers
      • 3.3.1.3. Threat of substitutes
      • 3.3.1.4. Threat of new entrants
      • 3.3.1.5. Competitive rivalry
    • 3.3.2. PESTEL Analysis
      • 3.3.2.1. Political landscape
      • 3.3.2.2. Economic landscape
      • 3.3.2.3. Social landscape
      • 3.3.2.4. Technological landscape
      • 3.3.2.5. Environmental landscape
      • 3.3.2.6. Legal landscape

Chapter 4. U.S. Dural Sealants and Fibrin Glues Market: CPT Procedure Codes Estimates & Trend Analysis

  • 4.1. Segment Dashboard
  • 4.2. U.S. Dural Sealants and Fibrin Glues Market: CPT Procedure Codes Movement Analysis
  • 4.3. U.S. Dural Sealants and Fibrin Glues Market by CPT Procedure Codes Outlook (USD Million)
  • 4.4. Market Size & Forecasts and Trend Analyses, 2024 to 2035 for the following
  • 4.5. 61510 / 61512 - Craniotomy for Supratentorial Lesion Removal
    • 4.5.1. 61510 / 61512 - Craniotomy for Supratentorial Lesion Removal Market Revenue Estimates and Forecasts, 2024 - 2035 (USD Million)
  • 4.6. 61320 - 61323 - Craniectomy or Craniotomy, Decompressive (With or Without Duraplasty)
    • 4.6.1. 61320 - 61323 - Craniectomy or Craniotomy, Decompressive (With or Without Duraplasty) Market Revenue Estimates and Forecasts, 2024 - 2035 (USD Million)
  • 4.7. 61518- Craniotomy for Infratentorial/Posterior Fossa Lesion
    • 4.7.1. 61518- Craniotomy for Infratentorial/Posterior Fossa Lesion Market Revenue Estimates and Forecasts, 2024 - 2035 (USD Million)
  • 4.8. 62140 / 62141- Cranioplasty or Dural Reconstruction
    • 4.8.1. 62140 / 62141- Cranioplasty or Dural Reconstruction Market Revenue Estimates and Forecasts, 2024 - 2035 (USD Million)
  • 4.9. 63707- Repair of CSF Leak, Cranial or Spinal, Without Laminectomy
    • 4.9.1. 63707- Repair of CSF Leak, Cranial or Spinal, Without Laminectomy Market Revenue Estimates and Forecasts, 2024 - 2035 (USD Million)
  • 4.10. 63709 - Repair of CSF Leak or Pseudomeningocele with Laminectomy
    • 4.10.1. 63709 - Repair of CSF Leak or Pseudomeningocele with Laminectomy Market Revenue Estimates and Forecasts, 2024 - 2035 (USD Million)
  • 4.11. 63710- Dural Graft (Spinal)
    • 4.11.1. 63710- Dural Graft (Spinal) Market Revenue Estimates and Forecasts, 2024 - 2035 (USD Million)
  • 4.12. 63030 - Laminotomy/Laminectomy (Lumbar), Decompression of Nerve Root
    • 4.12.1. 63030 - Laminotomy/Laminectomy (Lumbar), Decompression of Nerve Root Market Revenue Estimates and Forecasts, 2024 - 2035 (USD Million)
  • 4.13. 63047 - Laminectomy, >1 Vertebral Segment, Lumbar
    • 4.13.1. 63047 - Laminectomy, >1 Vertebral Segment, Lumbar Market Revenue Estimates and Forecasts, 2024 - 2035 (USD Million)
  • 4.14. 22612 / 22630 - Posterior Spinal Fusion with Decompression
    • 4.14.1. 22612 / 22630 - Posterior Spinal Fusion with Decompression Market Revenue Estimates and Forecasts, 2024 - 2035 (USD Million)

Chapter 5. U.S. Dural Sealants and Fibrin Glues Market: End Use Estimates & Trend Analysis

  • 5.1. Segment Dashboard
  • 5.2. U.S. Dural Sealants and Fibrin Glues Market: End Use Movement Analysis
  • 5.3. U.S. Dural Sealants and Fibrin Glues Market by End Use Outlook (USD Million)
  • 5.4. Market Size & Forecasts and Trend Analyses, 2024 to 2035 for the following
  • 5.5. Hospitals
    • 5.5.1. Hospitals Market Revenue Estimates and Forecasts, 2024 - 2035 (USD Million)
  • 5.6. Ambulatory Surgical Centers
    • 5.6.1. Ambulatory Surgical Centers Market Revenue Estimates and Forecasts, 2024 - 2035 (USD Million)
  • 5.7. Specialty Clinics
    • 5.7.1. Specialty Clinics Market Revenue Estimates and Forecasts, 2024 - 2035 (USD Million)

Chapter 6. Competitive Landscape

  • 6.1. Market Participant Categorization
  • 6.2. Key Company Profiles
    • 6.2.1. Integra LifeSciences
      • 6.2.1.1. Company overview
      • 6.2.1.2. Financial performance
      • 6.2.1.3. Product benchmarking
      • 6.2.1.4. Strategic initiatives
    • 6.2.2. Stryker
      • 6.2.2.1. Company overview
      • 6.2.2.2. Financial performance
      • 6.2.2.3. Product benchmarking
      • 6.2.2.4. Strategic initiatives
    • 6.2.3. Baxter
      • 6.2.3.1. Company overview
      • 6.2.3.2. Financial performance
      • 6.2.3.3. Product benchmarking
      • 6.2.3.4. Strategic initiatives
    • 6.2.4. Ethicon (J&J)
      • 6.2.4.1. Company overview
      • 6.2.4.2. Financial performance
      • 6.2.4.3. Product benchmarking
      • 6.2.4.4. Strategic initiatives
    • 6.2.5. Takeda Pharmaceutical
      • 6.2.5.1. Company overview
      • 6.2.5.2. Financial performance
      • 6.2.5.3. Product benchmarking
      • 6.2.5.4. Strategic initiatives
    • 6.2.6. B. Braun Medical
      • 6.2.6.1. Company overview
      • 6.2.6.2. Financial performance
      • 6.2.6.3. Product benchmarking
      • 6.2.6.4. Strategic initiatives
    • 6.2.7. Cook Medical
      • 6.2.7.1. Company overview
      • 6.2.7.2. Financial performance
      • 6.2.7.3. Product benchmarking
      • 6.2.7.4. Strategic initiatives
    • 6.2.8. Polyganics
      • 6.2.8.1. Company overview
      • 6.2.8.2. Financial performance
      • 6.2.8.3. Product benchmarking
      • 6.2.8.4. Strategic initiatives

List of Tables

  • Table 1 List of secondary sources
  • Table 2 List of abbreviations
  • Table 3 U.S. dural sealants and fibrin glues market, by CPT procedure codes, 2024 - 2035 (USD Million)
  • Table 4 U.S. dural sealants and fibrin glues market, by end use, 2024 - 2035 (USD Million)

List of Figures

  • Fig. 1 Market research process
  • Fig. 2 Data triangulation techniques
  • Fig. 3 Primary research pattern
  • Fig. 4 Market research approaches
  • Fig. 5 Value-chain-based sizing & forecasting
  • Fig. 6 QFD modeling for market share assessment
  • Fig. 7 Market formulation & validation
  • Fig. 8 U.S. dural sealants and fibrin glues: market outlook
  • Fig. 9 U.S. dural sealants and fibrin glues market competitive insights
  • Fig. 10 Parent market outlook
  • Fig. 11 Related/ancillary market outlook
  • Fig. 12 Penetration and growth prospect mapping
  • Fig. 13 Industry value chain analysis
  • Fig. 14 U.S. dural sealants and fibrin glues market driver impact
  • Fig. 15 U.S. dural sealants and fibrin glues market restraint impact
  • Fig. 16 U.S. dural sealants and fibrin glues market strategic initiatives analysis
  • Fig. 17 U.S. dural sealants and fibrin glues market: CPT procedure codes movement analysis
  • Fig. 18 U.S. dural sealants and fibrin glues market: CPT procedure codes outlook and key takeaways
  • Fig. 19 61510 / 61512 - Craniotomy for supratentorial lesion removal market revenue estimates and forecasts, 2024 - 2035 (USD Million)
  • Fig. 20 61320 - 61323 - Craniectomy or craniotomy, decompressive (with or without duraplasty) market revenue estimates and forecasts, 2024 - 2035 (USD Million)
  • Fig. 21 61518- Craniotomy for infratentorial/posterior fossa lesion market revenue estimates and forecasts, 2024 - 2035 (USD Million)
  • Fig. 22 62140 / 62141- Cranioplasty or dural reconstruction market revenue estimates and forecasts, 2024 - 2035 (USD Million)
  • Fig. 23 63707- Repair of CSF leak, cranial or spinal, without laminectomy market revenue estimates and forecasts, 2024 - 2035 (USD Million)
  • Fig. 24 63709 - Repair of CSF leak or pseudomeningocele with laminectomy market revenue estimates and forecasts, 2024 - 2035 (USD Million)
  • Fig. 25 63710- Dural graft (spinal) market revenue estimates and forecasts, 2024 - 2035 (USD Million)
  • Fig. 26 63030 - Laminotomy/laminectomy (lumbar), decompression of nerve root market revenue estimates and forecasts, 2024 - 2035 (USD Million)
  • Fig. 27 63047 - Laminectomy, >1 vertebral segment, lumbar market revenue estimates and forecasts, 2024 - 2035 (USD Million)
  • Fig. 28 22612 / 22630 - Posterior spinal fusion with decompression market revenue estimates and forecasts, 2024 - 2035 (USD Million)
  • Fig. 29 U.S. dural sealants and fibrin glues market end use movement analysis
  • Fig. 30 U.S. dural sealants and fibrin glues market, end- use outlook key takeaways
  • Fig. 31 Hospitals market revenue estimates and forecasts, 2024 - 2035 (USD Million)
  • Fig. 32 Ambulatory surgical centers market revenue estimates and forecasts, 2024 - 2035 (USD Million)
  • Fig. 33 Specialty clinics market revenue estimates and forecasts, 2024 - 2035 (USD Million)
  • Fig. 34 Participant categorization- U.S. dural sealants and fibrin glues market
  • Fig. 35 Market share of key market players- U.S. dural sealants and fibrin glues market