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市场调查报告书
商品编码
1847202
欧洲牙科移植骨替代物市场:市场规模、份额和趋势分析(2025-2031 年)Dental Bone Graft Substitute Market Size, Share & Trends Analysis | Europe | 2025-2031 | Includes: Allografts, Xenografts, Synthetics, Dental Growth Factors & Dental Barrier Membranes |
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2024 年欧洲牙科移植骨替代物和其他生医材料市场价值约 3.55 亿欧元。预计到 2031 年将达到近 4.5 亿欧元,复合年增长率为 3.4%。
本报告涵盖牙移植骨替代物(DBGS)、牙齿生长因子、牙齿屏障膜(DBM)、局部抗菌牙周治疗、牙软组织再生。 DBGS包括同种异体移植、异质骨移植和复合材料,但不包括自体移植,因为自体移植取自患者自身组织,目前尚无商业化产品。牙齿生长因子类别包括士卓曼集团旗下Emdogain®的销售数据。 DBM市场分为可吸收型与不可吸收型两大类。牙软组织再生产品分为再生产品和创伤护理产品。
这反映了欧洲人口老化、植入数量不断增长以及临床医生和患者对再生牙科的广泛认知。该地区严格的同种异体移植规范、部分国家持续使用自体移植材料以及长期无牙患者数量减少导致口腔卫生状况逐步改善,都抑制了市场需求。儘管存在这些不利因素,但异质骨移植和合成材料的稳定应用,以及屏障膜和软组织产品的日益普及,预计将支撑市场在2031年之前保持持续成长。
市场概览
再生牙科材料是欧洲现代植入和牙周治疗的基石。 DBGS(牙科生物材料)支持齿槽窝保存、上颚窦提升、齿槽嵴增高和牙周缺损修復。牙科屏障膜引导组织再生并保护植体部位。局部牙周抗菌治疗可清除残留细菌,而软组织产品则促进植入和植骨周围的癒合。
西欧、北欧、中欧和南欧的需求情况各不相同。在植入市场成熟且自费模式较为完善的国家,异质骨移植和可吸收胶原蛋白膜更为普遍。同时,在文化偏好限制动物性产品或成本效益是主要驱动因素的国家,合成生物生医材料仍然十分重要。由于加工技术和品质保证的改进,同种异体移植在某些市场正在成长,但由于监管和组织库整合等原因,其整体应用率低于美国。
人口老化仍然是一个结构性因素。预计到2030年,65岁及以上人口将占欧洲总人口的约四分之一。老年人牙齿脱落、齿槽骨吸收和牙周炎的发生率较高,因此在植入前进行植骨的需求也较大。同时,广泛的预防性牙科保健和口腔卫生习惯的改善,使许多人群的牙齿状况得到改善,从而减缓了完全无牙病例的长期增长。这些因素共同作用,有利于再生性手术与植入和复杂牙周治疗的持续发展。
市场价值不仅反映手术量,还取决于材料配置、病例复杂程度和训练强度。优质异质骨移植和可吸收膜是两阶段和即时植入流程中的常规材料。对于偏好非动物源材料或需要特定吸收特性的诊所,合成树脂提供了更大的灵活性。软组织产品和创伤护理有助于伤口缝合,尤其是在使用薄型生物材料或早期癒合阶段需要额外保护的情况下。
市场驱动因素
口腔疾病的盛行率
根据全球疾病负担分析,重度牙周炎和无牙颚病例总数呈现上升趋势。在西欧,2021年约有6,000万人患有重度牙周炎,500万人患有无牙颌,预计到2050年,患病率和发病率都将进一步增加。关于无牙颌,2021年西欧报告的病例数为3700万例,到2050年将增至4800万例,同期发病率也将上升。这种疾病负担意味着对再生治疗的持续临床需求,包括拔牙窝的保存、垂直和水平齿槽嵴的形成以及最终修復前的软组织稳定。
人口老化
预计到2030年,65岁及以上人口将占欧洲人口的约25%。与老龄化相关的骨骼重塑以及糖尿病和骨质疏鬆症等全身性危险因子的高发,增加了植入治疗前后进行植骨的可能性。因此,在寻求固定修復的老年患者中,骨吸收垫(DBGS)和生物膜的使用率可能会继续保持在较高水准。
消费者意识和投资组合捆绑
随着植入的普及,植入供应商和经销商正将再生材料产品组合与植入线捆绑销售。专业的销售团队和临床教育计画正在提高人们对膜在引导骨再生和可预测治疗效果中的作用的认识。这种市场推广模式推动了对异质骨移植、复合材料和可吸收胶原蛋白膜的需求,这些材料已成为植入植入的标准辅助材料。
同种异体移植材料的接受度不断提高
随着製造商实施有效的加工流程、可追溯性和品质保证措施,先前人们对疾病传播的担忧已有所缓解。更清晰的安全性和监管合规讯息促使更多临床医生考虑使用同种异体移植来治疗特定类型的缺损,前提是其操作和重塑特性与手术相符。虽然同种异体移植的使用率仍低于美国,但在与组织库建立紧密伙伴关係并接受系统培训的中心,其接受度正在不断提高。
市场限制
改善口腔卫生
日常口腔卫生、氟化物涂抹和预防保健降低了长期无牙症的发生率。随着人口老化,人们的牙齿状况趋于自然,全植入植牙和广泛的根麵增容手术的绝对数量有所下降,但单颗植牙和节段植牙仍然很普遍。
继续依赖自体移植材料
自体骨移植仍在继续,尤其是在欧洲部分地区,外科医生的偏好和报销机制更倾向于选择口腔内供体部位。在法国等骨移植材料相对不发达的市场,这种情况尤其明显。自体骨移植正在取代商业性骨移植材料在水平和垂直骨增量手术中的需求,从而限制了同种异体骨、异质骨移植和复合材料的市场成长。
整合严格的同种异体移植通讯协定和组织库
欧洲对人体组织产品的监管非常严格。过去十年,日益严格的监管增加了组织库的营运成本,导致一些国家的组织库关闭。例如,在葡萄牙,由于组织库无法根据更新后的要求进行重组,同种异体移植的供应被迫停止。结果,核准的供应商数量减少,产品选择范围缩小,自体移植和经济实惠的合成材料逐渐被采用,平均售价被限制,同种异体移植的使用率也随之下降。
中欧和南欧部分地区的价格敏感性
许多植入病例由私人医生承担费用。在私人医疗支出较高的地区,临床医生可能更倾向于选择性价比高的合成材料,或仅在临床上最必要的情况下才使用膜材料。这将导致价格敏感型市场中高端产品组合的成长缓慢。
目标市场和数据范围
目标市场及区隔
牙科移植骨替代物(DBGS)
牙齿生长因子
包括EMDOGAINR的销售额
牙科屏障膜(DBM)
局部牙周抗菌治疗
牙科软组织创伤护理
对于每个细分市场,我们提供市场价值、销售、平均售价、成长率和企业市场占有率,以及截至 2021 年的销售业绩和截至 2031 年的预测数据。
竞争分析
2024年,盖斯特利希(Geistlich)将继续保持其在欧洲DBGS和整体生医材料市场的领先地位。这项优势源自于其在DBGS和DBM两大领域的领先地位。在DBGS领域,盖斯特利希凭藉其成熟的Bio-Oss®产品系列,在异质骨移植材料市场占据主导地位。在生物膜领域,Bio-Gide®因其易于操作、生物相容性和再形成性而被广泛用作可吸收胶原蛋白屏障。博蒂斯生物生医材料)凭藉其临床验证的成功案例、培训记录和长期稳定的业绩,继续成为牙周病医生和植入医生的首选。
博蒂斯生物材料公司预计在2024年将占据第二大市场。其关键优势在于与士卓曼集团的战略伙伴关係,后者持有博蒂斯30%的股份。这项合作关係将博蒂斯的再生产品与士卓曼在欧洲植入的领先地位结合,从而提升了产品可近性和联合行销的有效性。其旗舰产品包括TheraBone®(异质骨移植)和Maxgraft®(同种移植材料),为临床医生提供涵盖不同材料偏好和适应症的丰富产品组合。
PerioChip® 是欧洲局部抗菌牙周治疗市场的领先竞争者,在 2024 年的 DBGS 和生医材料类别中排名第三。其分销网络范围广泛。在欧洲,PerioChip® 由 Dexcel Pharma 透过德国、英国、比荷卢经济联盟、奥地利等地的子公司和合作伙伴进行销售,在义大利由 Curaden Healthcare 销售,在瑞士由 Karr Denta 销售。 PerioChip® 可有效降低牙周袋内的细菌负荷,从而完善牙周组织的再生和维护通讯协定,因此在专科诊所中得到广泛应用。
其他区域和本地供应商正在与合成 DBGS、不可吸收膜和特定软组织产品竞争,但市场仍然集中在那些能够支持教育、临床证据和可靠的物流,并能跨越多个监管要求不同的欧洲国家的公司。
科技与临床趋势
地区
本分析重点在于欧盟(EU)。
异质骨移植、同种移植、复合材料、屏障膜和软组织产品领域中,规模最大、成长最快的商机在哪里?
到 2031 年,人口老化和口腔疾病负担将如何影响治疗需求?
严格的同种异体移植法规和组织库整合将如何影响欧洲市场的产品取得和定价?
对于植入和再生牙龈移植而言,最有效的教育和产品组合推广策略是什么?
Geistlich、Botiss Biomaterials 和 PerioChip® 等领导企业如何定位?它们的产品组合对 DBGS 和膜领域的竞争对手意味着什么?
在哪些方面,对自体移植的依赖将继续限制DBGS的采用,以及合成膜和靶向膜的选择将如何满足临床需求。
哪些技术和工作流程趋势将提高垂直和水平义肢、义肢接受腔保存和软组织管理的可预测性?
我们如何协调培训、库存和病例记录,以实现多中心诊所和转诊网路结果的标准化?
iData Research 的《欧洲牙科移植骨替代物和其他生医材料市场报告》透过程序感知模型、企业市场占有率分析和定价详情来回答这些问题,以帮助您量化需求、规划您的投资组合策略、指南区域市场进入,并优先考虑教育,以支持可预测的再生结果。
图表清单
图表列表
欧洲牙科移植骨替代物及其他生医材料市场概览
竞争分析
市场趋势
市场趋势
流程分段
市场区隔
重要报告更新
版本历史记录
调查方法
全球关税的影响
欧洲牙科移植骨替代物及其他生医材料市场概览
国家概况
程式编号
牙科骨移植替代物市场
牙科生长因子市场
牙科屏障膜市场
区域抗菌牙周病治疗市场
牙科软组织再生市场
The European dental bone graft substitute and other biomaterials market was valued at nearly €355 million in 2024. It is projected to grow at a compound annual growth rate of 3.4 percent to reach nearly €450 million in 2031.
This report covers dental bone graft substitutes (DBGSs), dental growth factors, dental barrier membranes (DBMs), local antimicrobial periodontal treatment, and dental soft tissue regeneration. Within DBGSs, the analysis includes allografts, xenografts, and synthetics, while autografts are excluded since they are harvested from the patient and are not sold commercially. The dental growth factor category includes sales of Straumann Group's Emdogain(R). The DBM market is split into resorbable and non-resorbable segments. Dental soft tissue regeneration is segmented into regenerative products and wound care products.
The market's trajectory reflects Europe's aging population, growing implant placement volumes, and broader awareness of regenerative dentistry among clinicians and patients. Demand is tempered by the region's stringent allograft protocols, continued use of autograft materials in selected countries, and gradual improvements in baseline oral health that reduce the long-term pool of fully edentulous patients. Even with these headwinds, steady adoption of xenograft and synthetic materials, plus expanding usage of barrier membranes and soft tissue products, is expected to support consistent market growth through 2031.
Market Overview
Regenerative dental materials are fundamental to modern implant and periodontal practice in Europe. DBGSs support socket preservation, sinus augmentation, ridge augmentation, and periodontal defect repair. Dental barrier membranes guide tissue regeneration and protect graft sites. Local antimicrobial periodontal treatments address residual bacterial burden, and soft tissue products promote closure and healing around implants and grafts.
The demand profile varies across Western, Northern, Central, and Southern Europe. Countries with mature implant markets and strong private-pay segments show higher penetration of xenografts and resorbable collagen membranes. In parallel, synthetic biomaterials remain important where cultural preferences limit animal-derived products or where procurement emphasizes cost stability. Allografts have grown in selected markets due to better processing techniques and quality assurance, though overall European uptake trails the United States because of regulation and tissue bank consolidation.
Aging demographics remain the dominant structural driver. By 2030, individuals 65 and older are expected to represent about a quarter of Europe's total population. Older adults experience higher rates of tooth loss, alveolar bone resorption, and periodontitis, which increases the need for grafting prior to implant placement. At the same time, widespread preventive dentistry and more routine hygiene compliance have improved dentition for many cohorts, which moderates long-run growth in fully edentulous cases. The net effect still favors steady expansion of regenerative procedures aligned with implants and complex periodontal therapy.
Market value reflects not only procedure volumes but also material mix, case complexity, and training intensity. Premium xenografts and resorbable membranes are used routinely in two-stage and immediate implant workflows. Synthetics add flexibility for practices that prefer non-animal materials or that need specific resorption profiles. Soft tissue products and wound care items support closure, especially in thin biotype cases and when clinicians need extra protection during early healing.
Market Drivers
Prevalence of oral disease
Global burden-of-disease analyses indicate large and rising totals of severe periodontitis and edentulism. In Western Europe, about 60 million people were living with severe periodontitis in 2021 with 5 million incident cases, and projections suggest a further rise in both prevalence and incidence by 2050. For edentulism, Western Europe reported 37 million cases in 2021, moving toward 48 million by 2050, with incidence also increasing over the same period. These burdens translate into sustained clinical demand for regenerative intervention, whether to preserve extraction sockets, build vertical or horizontal ridge volume, or stabilize soft tissues prior to definitive prosthetics.
Aging population
By 2030, people aged 65+ are expected to comprise about 25 percent of Europe's population. Age-related bone remodeling and the higher prevalence of systemic risk factors like diabetes and osteoporosis increase the likelihood of grafting before or during implant therapy. As a result, DBGSs and membranes will continue to be used at higher rates in older patients who want fixed restorations.
Greater consumer awareness and portfolio bundling
As implants gain popularity, implant vendors and distributors are bundling regenerative portfolios alongside implant lines. Dedicated sales teams and clinical education programs have raised awareness of guided bone regeneration and the role of membranes in predictable outcomes. This go-to-market model supports pull-through demand for xenografts, synthetics, and resorbable collagen membranes as standard adjuncts to implant placement.
Growing acceptance of allograft materials
Earlier concerns about disease transmission have eased as manufacturers implement validated processing, traceability, and quality assurance. With clearer messaging around safety and regulatory compliance, more clinicians are considering allograft options for specific defect types where handling and remodeling profiles fit their technique. Although allograft use remains lower than in the United States, acceptance is improving in centers with strong tissue bank partnerships and structured training.
Market Limiters
Improved oral health
Routine hygiene, fluoridation policies, and preventive care have reduced the long-term incidence of complete edentulism. As older cohorts retain more natural dentition, the absolute number of full-arch implant reconstructions and extensive ridge augmentations is moderated, even as single-tooth and segmental sites remain active.
Continued reliance on autograft materials
Autograft harvesting persists in parts of Europe, especially where surgeon preference and reimbursement frameworks favor intraoral donor sites. This is most evident in markets like France, where the DBGS segment is comparatively underdeveloped. Autograft usage displaces commercial DBGS demand in horizontal and vertical augmentation cases, limiting unit growth for allografts, xenografts, and synthetics.
Stringent allograft protocols and tissue bank consolidation
European regulation of human tissue products is strict. Over the last decade, tighter rules increased operating costs for tissue banks, leading to closures in several countries. In Portugal, for example, allograft distribution ceased when tissue banks could not reorganize under updated requirements. The result is a smaller pool of approved suppliers, constrained product choice, and an ongoing shift to autografts or cost-effective synthetics, which can cap average selling prices and dampen allograft penetration.
Price sensitivity in parts of Central and Southern Europe
Private-pay dynamics dominate many implant cases. In regions where out-of-pocket spending is high, clinicians may favor synthetic materials with attractive value profiles or limit membrane usage to the most clinically necessary cases. This keeps premium mix growth modest in price-sensitive markets.
Market Coverage and Data Scope
Markets Covered and Segmentation
Dental Bone Graft Substitutes (DBGSs)
Dental Growth Factor
Includes Emdogain(R) sales
Dental Barrier Membranes (DBMs)
Local Antimicrobial Periodontal Treatment
Dental Soft Tissue Wound Care
For every segment, the report presents market values, unit sales, ASPs, growth rates, and company shares, with historical data to 2021 and forecasts to 2031.
Competitive Analysis
Geistlich remained the leading competitor in the total European DBGS and biomaterials market in 2024. Its dominance stems from leadership in both the DBGS and DBM segments. In DBGS, Geistlich holds a majority share in xenografts, supported by the well-established Bio-Oss(R) product line. In membranes, Bio-Gide(R) is widely used as a resorbable collagen barrier due to its handling, biocompatibility, and remodeling behavior. The brand's clinical legacy, training footprint, and long record of documentation continue to reinforce preference among periodontists and implant surgeons.
botiss biomaterials held the second-largest share of the total market in 2024. A key strength is its strategic partnership with Straumann Group, which holds a 30 percent stake in botiss. This relationship aligns botiss regenerative products with Straumann's leadership in implants across Europe, improving access and co-selling effectiveness. Flagship products include cerabone(R) (xenograft) and maxgraft(R) (allograft), which give clinicians a portfolio that spans material preferences and indications.
PerioChip(R) was the leading competitor in the European local antimicrobial periodontal treatment market in 2024, placing third overall in the total DBGS and biomaterials landscape. Distribution is supported by an extensive network. In Europe, Dexcel Pharma markets PerioChip(R) through subsidiaries and partners in Germany, the U.K., Benelux, Austria, and other countries. Additional distribution is provided by Curaden Healthcare in Italy and Karr Denta in Switzerland. PerioChip(R)'s role in reducing bacterial load within periodontal pockets complements regenerative and maintenance protocols, which helps anchor its adoption across specialist practices.
Other regional and local suppliers compete in synthetic DBGS, non-resorbable membranes, and selected soft tissue products. However, the market remains concentrated around companies that can support education, clinical evidence, and reliable logistics across multiple European countries with different regulatory expectations.
Technology and Practice Trends
Geography
The analysis covers the European Union.
Where are the largest and fastest-growing opportunities across xenografts, allografts, synthetics, barrier membranes, and soft tissue products.
How the aging population and oral disease burden will shape procedure demand through 2031.
How stringent allograft regulations and tissue bank consolidation affect product access and pricing in different European markets.
Which education and portfolio bundling strategies are most effective for implant and regenerative pull-through.
How leaders such as Geistlich, botiss biomaterials, and PerioChip(R) are positioned, and what their portfolios imply for competition in DBGS and membranes.
Where autograft reliance will continue to limit DBGS adoption, and how synthetics and targeted membrane selection can bridge clinical needs.
What technology and workflow trends will improve predictability in vertical and horizontal augmentation, socket preservation, and soft tissue management.
How to align training, inventory, and case documentation to standardize results across multi-site practices and referral networks.
The European Dental Bone Graft Substitute and Other Biomaterials Market Report from iData Research answers these questions with procedure-aware models, company share analysis, and pricing detail. Use it to quantify demand, plan portfolio strategy, guide regional market entry, and prioritize education that supports predictable regenerative outcomes.
Table Of Contents
List Of Figures
List Of Charts
European Dental Bone Graft Substitute And Other Biomaterials Market Overview
Competitive Analysis
Market Developments
Market Trends
Procedure Segmentation
Market Segmentation
Key Report Updates
Version History
Research Methodology
Impact Of Global Tariffs
European Dental Bone Graft Substitute And Other Biomaterials Market Overview
Country Profiles
Procedure Numbers
Dental Bone Graft Substitute Market
Dental Growth Factor Market
Dental Barrier Membrane Market
Local Antimicrobial Periodontal Treatment Market
Dental Soft Tissue Regeneration Market