全球内视镜黏膜下剥离术（ESD）刀市场：市场规模、份额和趋势分析（2026-2032 年）

预计2025年，全球内视镜黏膜下剥离术（ESD）刀市场规模将超过3.59亿美元。预计到2032年，该市场将以7.6%的复合年增长率成长，达到约6亿美元。

本报告涵盖内视镜黏膜下剥离术（ESD）刀，这是一种能够实现微创切除胃肠道病变的关键附件。报告量化了ESD刀的销售、平均售价（ASP）、市场价值、成长率和企业市场占有率。此外，报告还涵盖了市场趋势和驱动因素、近期併购活动以及技术发展。报告提供了2022年至2024年的历史数据以及至2032年的预测数据。

该报告反映了 ESD 技术和刀具设计的进步如何推动手术的普及，改善患者的治疗效果，并随着医院和临床医生转向创伤较小的治疗途径，支持市场的持续扩张。

市场概览

内视镜黏膜下剥离术（ESD）刀的设计目的是为了精确、可控地切除早期胃肠道病变，包括肿瘤和息肉，而无需进行开放性手术。 ESD 使医生能够将病变组织从黏膜下层完整剥离，从而提高诊断准确性并最大限度地减少復发。

自1990年代末期引进以来，器械设计、影像技术和操作者培训方面的创新显着推动了该手术的发展。 ESD刀仍然是这些手术的基石，它提供了安全有效切除所需的精确度和多功能性。

尖端设计、导电性和控制机制的进步提高了内视镜黏膜下剥离术（ESD）刀的可靠性，使医生能够以更少的併发症进行一致的整块切除。随着越来越多的医院安装相容ESD的系统以及临床医生技能的提高，全球ESD手术总量持续成长。

ESD技术的日益普及反映了微创内视镜手术的整体发展趋势。与传统开放性手术或腹腔镜手术相比，ESD具有住院时间更短、患者不适感更少、恢復更快等优势。预计这些临床和经济效益将持续推动市场需求，直至2032年。

随着视觉化和电外科技术的创新，ESD有望变得更加复杂，并成为许多早期胃肠道癌症和癌前病变的首选治疗方法，从而提高ESD刀在全球胃肠内视镜市场的重要性。

市场驱动因素

单块切除

ESD刀的一个关键优势是能够进行整块切除，与分块切除技术相比，可以进行更准确的组织学诊断，并降低復发风险。

临床研究表明，使用内视镜黏膜下剥离术（ESD）切除的肿瘤中，96%可整块切除，且后续观察期间未见局部復发。完全切除的可能性转化为更佳的长期治疗效果和医师的信心，使得ESD越来越成为早期胃肠道病变的首选治疗方法。

改进的刀具技术

• 自1998年首次问世以来，ESD刀一直在不断改进。现代ESD刀大致可分为两大类：钝头刀和截尖刀。每种刀型都有独特的操作优势，取决于病灶的位置和黏膜下层的厚度。

旋转控制、可调节长度鞘套和多功能电极等创新提高了精度并缩短了手术时间，製造商不断提供各种刀尖形状和附件，提高了对不同病变类型和器官位置的适应性。

这些改进提高了手术的成功率和安全性，使内视镜医师能够更稳定地进行 ESD 手术，从而在全球范围内广泛应用。

性价比高

ESD手术可达到与开放性手术或腹腔镜手术相当的疗效，但费用却低得多。无需进行完全的外科手术即可达到根治性切除，从而减少住院时间、麻醉需求和术后併发症。

对于成本受限的医院和医疗保健系统而言，静电除尘术 (ESD) 提供了一种有效的替代方案，既能显着节省成本，又能保持临床疗效。随着支付方和政策制定者认识到这些优势，越来越多的市场开始逐步扩大 ESD 手术的报销范围。这一趋势进一步增强了 ESD 技术的经济效益，并提高了对高品质 ESD 手术刀的需求。

简化流程并扩大培训

工作流程效率的提高和培训计画的日益普及正在推动医生广泛采用内视镜黏膜下剥离术（ESD）。模拟工具、导师网路和专门的ESD课程使内视镜医师能够在独立进行手术前安全地累积经验。

对专家教育的这项投资缩短了学习曲线，提高了操作成功率，从而支持了整个 ESD 市场的成长，并促进了 ESD 刀具在全球范围内的普及。

市场限制

併发症风险

儘管内视镜黏膜下剥离术（ESD）具有显着优势，但与内视镜黏膜切除术（EMR）等其他手术相比，其穿孔和出血的风险相对较高。 ESD 的复杂性要求操作者俱备精准的控制能力和丰富的经验，训练不足可能会增加併发症的发生率。

对于较小或较易触及的病变，一些医生仍然偏好 EMR，因为它风险较低，但对潜在併发症的担忧可能会限制 ESD 专家和资源有限的中心采用 EMR。

静电放电防护专业人员数量有限

成功的环境永续发展教育需要专门的技能，在许多地区，受过训练的环境永续发展教育专家的数量有限，尤其是在日本和西方的一些学术中心之外。

因此，患者通常被转诊至外科或电子病历科，而非内视镜黏膜下剥离术（ESD）。扩大培训和指导机会对于更广泛地推广应用至关重要。如果没有更多培训机会和更完善的报销政策，某些市场的手术量成长可能仍将保持低迷。

采用障碍和资源需求

与标准内视镜手术相比，ESD 手术通常需要更长的手术时间和专门的设备，包括需要专门的电外科设备、先进的影像处理和麻醉支持，这可能会限制其在资源匮乏的中心的普及。

此外，在某些市场，健保报销机制可能尚未完全涵盖内视镜黏膜下剥离术（ESD），这降低了医院投资必要基础设施的奖励。解决这些系统层面的障碍对于维持长期成长至关重要。

目标市场和数据范围

定量范围

市场规模、市占率、市场预测、成长率、销售量、平均售价

定性范围

影响静电放电防护刀具需求的成长趋势、限制因素、竞争对手分析及SWOT分析、併购活动、公司简介及产品系列、FDA召回事件、颠覆性技术、疾病概述

时期

基准年为2025年，预测期间为2026-2032年，历史资料为2022-2024年。

数据来源

对产业领导者的初步调查、政府医生资料、监管文件、医院采购资料、进出口资料库、iData Research内部资料库

方法注记

收入模型是根据销售量乘以平均售价计算得出的，并根据一次性及可重复使用设备的程序数据和更换假设检验。

竞争分析

Olympus Corporation在2025年以绝对市占率引领全球静电放电防护刀市场。其领先地位得益于丰富的产品系列和悠久的内视镜创新历史。静电放电防护刀最初在日本流行起来，Olympus凭藉早期应用优势迅速确立了市场主导地位。

在奥林巴斯公司的众多产品中，ITknife nano尤其引人注目。这款一次性电外科刀针对薄层黏膜下层和大肠手术进行了优化，具有出色的操作性和抗感染性。Olympus正透过持续的研发和临床医生培训倡议，在全球范围内拓展该产品线，并巩固其市场地位。

ERBE Elektromedizin GmbH 在电外科手术刀市场排名第二。其 HybridKnife 将切割和凝血功能整合于单一器械中，无需更换器械即可实现多种功能。这种双重功能简化了医院的库存管理，并提高了手术效率。 HybridKnife 的多功能性以及与 ERBE 先进电外科产生器的兼容性，巩固了该公司作为全球领先供应商的地位。

波士顿科学公司凭藉其多元化的高性能内视镜黏膜下剥离刀产品组合，在2025年排名第三。该公司产品设计着重精准性、耐用性和人体工学，旨在提升医师在黏膜下剥离术中的操作便利性。波士顿科学公司持续投资内视镜黏膜下剥离术专用技术研发，进一步巩固其在先进内视镜市场的竞争地位。

整体而言，ESD刀市场集中在少数几家拥有成熟内视镜产品组合和全球分销网络的跨国公司手中。竞争主要体现在价格、技术创新、培训合作以及工作流程整合等。

科技与临床趋势

多功能 ESD 刀具结合了切割、注射和凝血功能，减少了更换器械的需要，提高了效率和安全性。

一次性刀具设计越来越受欢迎，以防止交叉污染并简化再处理流程。

水刀辅助和旋转刀片等尖端设计的进步提高了精度并缩短了手术时间。

高解析度窄频视觉化系统增强了影像融合，从而能够更准确地勾勒出病灶边界和黏膜下层。

扩大和标准化的培训持续推动全球范围内的普及，模拟平台和导师制计划帮助临床医生更快地熟练相关技能。

区域指南正在更新，将 ESD 纳入早期胃肠道癌症的第一线治疗方法。

地区

本期内容涵盖全球，包括北美、欧洲、亚太地区、拉丁美洲以及中东和非洲。

调查方法附录与简称

目录

图表清单

图表列表

调查方法

全球关税的影响

内视镜黏膜下剥离术（ESD）刀市场

• 执行摘要
  • 全球内视镜黏膜下剥离术（ESD）刀市场概览
  • 竞争分析
  • 目标区域
• 介绍
• 市场分析与预测
• 驾驶员和约束装置
• 竞争市占率分析

简称

The global endoscopic submucosal dissection (ESD) knife market was valued at over $359 million in 2025. The market is projected to grow at a compound annual growth rate (CAGR) of 7.6 percent, reaching approximately $600 million by 2032.

This report covers endoscopic submucosal dissection knives, key accessories that enable minimally invasive removal of gastrointestinal lesions. It quantifies unit sales, average selling prices (ASPs), market values, growth rates, and company shares, and includes market drivers and limiters, recent mergers and acquisitions, and technology trends. The report provides historical data from 2022 to 2024 and forecasts through 2032.

The scope reflects how advancements in ESD techniques and knife designs are driving procedural adoption, improving patient outcomes, and supporting continued market expansion as hospitals and clinicians transition toward less invasive treatment pathways.

Market Overview

Endoscopic submucosal dissection (ESD) knives are designed to perform precise and controlled resections of early-stage gastrointestinal lesions, including tumors and polyps, without requiring open surgery. ESD enables physicians to dissect lesions from the submucosal layer in one piece, improving diagnostic accuracy and minimizing recurrence.

Since the introduction of ESD in the late 1990s, the procedure has evolved significantly through innovations in device design, imaging, and operator training. ESD knives have become the cornerstone of these procedures, providing the precision and versatility required for safe and effective resections.

Advances in tip design, electrical conductivity, and control mechanisms have enhanced the reliability of ESD knives, allowing physicians to achieve consistent en bloc resections with fewer complications. As more hospitals adopt ESD-capable systems and as clinician proficiency improves, the overall number of ESD procedures performed globally continues to rise.

The growing acceptance of ESD reflects the broader movement toward minimally invasive endoscopic therapies. Compared to traditional open or laparoscopic surgery, ESD offers shorter hospital stays, reduced patient discomfort, and faster recovery times. These clinical and economic benefits are expected to continue fueling market demand through 2032.

As innovations in visualization and electrosurgical technology further refine the technique, ESD is expected to become the preferred treatment for many early gastrointestinal cancers and precancerous lesions, reinforcing the importance of ESD knives within the global GI endoscopy market.

Market Drivers

Single-Fragment Resection

One of the defining advantages of ESD knives is their ability to achieve single-fragment (en bloc) resection. Removing lesions in one piece enables more accurate histological diagnosis and lowers recurrence risk compared to piecemeal resection techniques.

Clinical studies have shown that as many as 96 percent of tumors resected with ESD knives are removed in one piece, with no local recurrence observed during follow-up. The ability to secure complete resections supports improved long-term outcomes and greater confidence among physicians, making ESD knives increasingly preferred for early-stage gastrointestinal lesions.

Improved Knife Technology

• Since their first introduction in 1998, ESD knives have undergone continuous refinement. Modern knives fall into two main categories: blunt-tip designs and tip-cutting designs. Each type offers unique procedural advantages depending on lesion location and thickness of the submucosal layer.

Innovations such as rotational control, adjustable sheath lengths, and multi-functional electrodes have increased precision and reduced procedure time. Manufacturers continue to expand the range of knife tip geometries and attachments, improving versatility across lesion types and organ sites.

These improvements enhance procedural success and safety while allowing endoscopists to perform ESD with greater consistency, thereby supporting increased adoption worldwide.

Cost-Effectiveness

ESD offers comparable therapeutic outcomes to open and laparoscopic surgery but at a fraction of the cost. The ability to achieve curative resection without full surgical intervention reduces hospitalization, anesthesia requirements, and post-operative complications.

For hospitals and healthcare systems under cost constraints, ESD represents an effective alternative that delivers measurable savings while maintaining clinical efficacy. As payers and policymakers recognize these advantages, reimbursement for ESD procedures is gradually expanding across more markets. This trend further enhances the economic rationale for ESD adoption, reinforcing demand for high-quality ESD knives.

Procedural Efficiency and Training Expansion

Improved workflow efficiency and increased availability of training programs have encouraged broader physician adoption. Simulation tools, mentorship networks, and dedicated ESD courses now enable endoscopists to gain experience safely before performing procedures independently.

This investment in professional education reduces the learning curve and increases procedural success rates, supporting overall growth of the ESD market and driving higher utilization of ESD knives globally.

Market Limiters

Risk of Complications

Although ESD offers significant benefits, it carries a relatively high risk of perforation and bleeding compared to alternative procedures such as endoscopic mucosal resection (EMR). The complexity of ESD requires precise control and experience, and incomplete training can increase complication rates.

Because EMR presents a lower risk profile, some physicians still prefer it for smaller or more accessible lesions. Concerns about potential complications may limit adoption in centers with limited ESD expertise or resources.

Limited Number of ESD Experts

The successful execution of ESD requires specialized skill. In many regions, the number of trained ESD practitioners remains limited, particularly outside Japan and select academic centers in Europe and North America.

As a result, patients are often referred for surgery or EMR rather than ESD. Expanding access to training and mentorship is essential for broader adoption. Unless training opportunities increase and reimbursement policies improve, procedural volume growth may remain constrained in some markets.

Adoption Barriers and Resource Requirements

ESD procedures typically demand longer operating times and specialized equipment compared to standard endoscopic procedures. The need for dedicated electrosurgical units, advanced imaging, and anesthesia support can limit availability in lower-resource facilities.

In addition, reimbursement structures in certain markets may not yet fully cover ESD procedures, reducing incentives for hospitals to invest in the necessary infrastructure. Addressing these system-level barriers will be critical to sustaining long-term growth.

Market Coverage and Data Scope

Quantitative Coverage

Market size, market shares, market forecasts, growth rates, units sold, and average selling prices.

Qualitative Coverage

Growth trends, limiters, competitive analysis and SWOT for top competitors, mergers and acquisitions, company profiles and product portfolios, FDA recalls, disruptive technologies, and disease overviews that shape demand for ESD knives.

Time Frame

Base year 2025, forecasts 2026 to 2032, historical data 2022 to 2024.

Data Sources

Primary interviews with industry leaders, government physician data, regulatory filings, hospital procurement data, import and export databases, and the iData Research internal database.

Method Note

Revenue is modeled from units multiplied by ASP, validated against procedural data and replacement assumptions for disposable and reusable devices.

Competitive Analysis

Olympus Corporation was the leading competitor in the global ESD knife market in 2025, holding a commanding share. The company's leadership is supported by its broad product portfolio and long history in endoscopic innovation. ESD knives first gained popularity in Japan, where Olympus capitalized on early adoption to establish a dominant presence.

Among its products, the ITknife nano is particularly noteworthy. This single-use electrosurgical knife is optimized for thin submucosal layers and colon procedures, offering excellent maneuverability and infection resistance. Olympus has expanded this product line globally, reinforcing its market position through ongoing R&D and clinician training initiatives.

ERBE Elektromedizin GmbH ranked second in the ESD knife market. The company's HybridKnife combines cutting and coagulation capabilities in one instrument, enabling multiple functions without changing devices. This dual functionality simplifies inventory management for hospitals and improves procedural efficiency. The versatility of the HybridKnife and its compatibility with ERBE's advanced electrosurgical generators have helped solidify the company's position as a leading global supplier.

Boston Scientific Corporation ranked third in 2025, supported by a diverse portfolio of high-performance ESD knives. The company's product designs focus on precision, durability, and ergonomic handling, which enhance physician control during submucosal dissection. Boston Scientific continues to invest in developing ESD-specific technologies to strengthen its competitive presence in the advanced endoscopy market.

Overall, the ESD knife market is concentrated among a small group of multinational companies with established endoscopy portfolios and global distribution networks. Competition centers on innovation, training partnerships, and workflow integration, rather than price alone.

Technology and Practice Trends

Multi-functional ESD knives that combine cutting, injection, and coagulation capabilities are reducing the need for device exchanges, improving efficiency and safety.

Single-use knife designs are becoming more prevalent to prevent cross-contamination and streamline reprocessing workflows.

Advancements in tip design, such as water-jet assistance and rotatable blades, are improving precision and reducing procedure times.

Enhanced imaging integration through high-definition and narrow-band visualization systems allows for better delineation of lesion margins and submucosal layers.

Training expansion and standardization continue to drive global adoption, with simulation platforms and mentorship programs helping clinicians achieve proficiency faster.

Regional guidelines are being updated to include ESD as a first-line treatment option for early-stage gastrointestinal cancers, which is expected to further accelerate procedural growth.

Geography

This edition provides complete global coverage, including North America, Europe, Asia-Pacific, Latin America, and the Middle East & Africa.

Methodology Appendix and Acronym Glossary

Why This Report

Where are the largest and fastest-growing opportunities within the global ESD knife market

How are advancements in tip design, imaging, and procedural techniques shaping growth

Which factors are driving the shift toward minimally invasive resections and how do they impact market value

How will the expansion of training programs and cost-effectiveness of ESD influence adoption across regions

What are the key risks to growth, including procedural complexity and limited expert availability

How do Olympus, ERBE, and Boston Scientific position their portfolios and training partnerships to maintain leadership

The Global Endoscopic Submucosal Dissection Knife Market Report from iData Research answers these questions with procedure-based market models, company share analysis, and pricing data. Use it to evaluate market potential, benchmark competitive positioning, and plan strategies for entry or expansion in the advanced GI endoscopy market.

TABLE OF CONTENT

Table Of Contents

List Of Figures

List Of Charts

Research Methodology

• Step 1: Project Initiation & Team Selection
• Step 2: Prepare Data Systems And Perform Secondary Research
• Step 3: Preparation For Interviews & Questionnaire Design
• Step 4: Performing Primary Research
• Step 5: Research Analysis: Establishing Baseline Estimates
• Step 6: Market Forecast And Analysis
• Step 7: Identify Strategic Opportunities
• Step 8: Final Review And Market Release
• Step 9: Customer Feedback And Market Monitoring

Impact Of Global Tariffs

Endoscopic Submucosal Dissection Knife Market

• 10.1 Executive Summary
  • 10.1.1 Global Endoscopic Submucosal Dissection Knife Market Overview
  • 10.1.2 Competitive Analysis
  • 10.1.3 Regions Included
• 10.2 Introduction
• 10.3 Market Analysis And Forecast
• 10.4 Drivers And Limiters
  • 10.4.1 Market Drivers
  • 10.4.2 Market Limiters
• 10.5 Competitive Market Share Analysis

Abbreviations

LIST OF CHARTS

• Chart 10-1: Endoscopic Submucosal Dissection Knife Market, Global, 2025 & 2032
• Chart 10-2: Endoscopic Submucosal Dissection Knife Procedures, Global, 2025
• Chart 10-3: Endoscopic Submucosal Dissection Knife Market, Global, 2022 - 2032
• Chart 10-4: Leading Competitors, Endoscopic Submucosal Dissection Knife Market, Global, 2025

LIST OF FIGURES

• Figure 10-1: Endoscopic Submucosal Dissection Knife Regions Covered, Global (1 of 2)
• Figure 10-2: Endoscopic Submucosal Dissection Knife Regions Covered, Global (2 of 2)
• Figure 10-3: Endoscopic Submucosal Dissection Knife Market, Global, 2022 - 2032
• Figure 10-4: Units Sold by Region, Endoscopic Submucosal Dissection Knife Market, Global, 2022 - 2032
• Figure 10-5: Average Selling Price by Region, Endoscopic Submucosal Dissection Knife Market, Global, 2022 - 2032 (US$)
• Figure 10-6: Market Value by Region, Endoscopic Submucosal Dissection Knife Market, Global, 2022 - 2032 (US$M)
• Figure 10-7: Leading Competitors, Endoscopic Submucosal Dissection Knife Market, Global, 2025