市场调查报告书
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2023-2028 年按作用机制、药物类别、活性谱、给药途径、最终用户和地区分類的抗生素市场报告Antibiotics Market Report by Action Mechanism, Drug Class, Spectrum of Activity, Route of Administration, End User, and Region 2023-2028 |
2022年全球抗生素市场规模达到494亿美元。展望未来, IMARC Group预计到2028年市场规模将达到626亿美元,2022-2028年复合年增长率(CAGR)为4.0%。肺炎、结核病和其他传染病在个体中的盛行率不断上升,抗菌素抗药性(AMR)的发生率不断上升,以及生物技术和药物发现技术的进步是推动市场的一些主要因素。
抗生素是一类用于治疗细菌感染的药物。它们以多种形式广泛存在,例如丸剂、胶囊、注射剂、乳膏和软膏。它们可以杀死细菌或抑制其生长,以有效消除感染。它们针对细菌细胞内的特定机製或结构,干扰其重要功能并阻止其繁殖。除此之外,它们还有助于增强个体的免疫系统。因此,抗生素被用来治疗各种疾病,例如泌尿道感染(UTI)、呼吸道感染、皮肤感染和某些个别性传染病。
目前,世界各地群众中多种慢性病的盛行率不断上升,推动了市场的成长。此外,抗生素透过全球线上和线下商店的广泛供应正在加强市场的成长。除此之外,对局部抗生素的需求不断增长,因为它们可以最大限度地降低个人手术部位感染的风险,并且正在对市场产生积极影响。此外,为了保障动物健康和福利以及支持食品安全,畜牧业中越来越多地使用抗生素,这也促进了市场的成长。与此一致的是,老年人口对抗生素的需求不断增长正在支持市场的成长。此外,消费者对预防保健措施的认识不断增强正在推动市场的成长。
传染病病率上升
全球范围内,肺炎、结核、泌尿道感染(UTI)、胃肠道感染和败血症等传染病的盛行率呈上升趋势。由于卫生设施不足,导致细菌感染传播,人们越来越多地遭受这些疾病的困扰。此外,抗药性细菌的出现也增加了对抗生素的需求。对有助于治疗这些感染的有效抗生素的需求不断增加。抗生素是专门针对和消除细菌感染而设计的。它们能有效杀死体内的细菌并促进个体癒合。此外,抗生素是在医疗保健专业人员的指导下使用的,以优化患者的治疗效果。
抗菌素抗药性 (AMR) 的发生率增加
全球抗生素抗药性(AMR)的发生率不断上升,推动了抗生素市场的发展。当细菌、病毒、寄生虫或真菌进化并对治疗它们的药物产生抗药性时,就会发生抗菌素抗药性。它降低了抗生素的有效性,导致感染时间更长、更严重、医疗费用增加以及个人死亡率高。抗生素的过度使用和滥用会导致抗药性细菌的产生,从而降低传统抗生素的效果。此外,多重抗药性菌株,如抗甲氧西林金黄色葡萄球菌(MRSA)和抗碳青霉烯类肠桿菌(CRE)也更为常见。这就需要开发新的抗生素或替代疗法来对抗这些抗药性菌株。
抗生素技术进步
生物技术、分子生物学和药物发现技术的创新有助于提高抗生素开发的效率和有效性。基因组学和高通量筛选可以识别潜在的药物标靶并筛选大型化合物库。此外,电脑辅助药物设计可以预测药物疗效并优化候选抗生素。这些技术进步简化了抗生素的发现过程,并减少了与传统方法相关的时间和成本。此外,诊断技术的进步,例如快速病原体识别和药物敏感性测试,有助于适当的抗生素选择和处方,从而改善患者的治疗效果。此外,技术进步有助于开发新的、更有效的抗生素来解决传染病和抗菌素抗药性。
IMARC Group提供了全球抗生素市场报告各细分市场主要趋势的分析,以及 2023 年至 2028 年全球、区域和国家层面的预测。我们的报告根据作用机制、药物类别、活性范围、给药途径和最终用户对市场进行了分类。
细胞壁合成抑制剂
蛋白质合成抑制剂
DNA合成抑制剂
RNA合成抑制剂
分枝菌酸抑制剂
其他的
细胞壁合成抑制剂代表最大的细分市场
报告根据行动机制对市场进行了详细的细分和分析。这包括细胞壁合成抑制剂、蛋白质合成抑制剂、DNA合成抑制剂、RNA合成抑制剂、霉菌酸抑制剂等。根据该报告,细胞壁合成是最大的部分。
细胞壁合成是一类针对细菌细胞壁的抗生素。这些抗生素会干扰细胞壁的合成过程,导致细胞壁损伤并最终导致细菌死亡。此外,青霉素、头孢菌素和碳青霉烯类是一些细胞壁合成抑制剂。它们透过抑制青霉素结合蛋白(PBP)的酶发挥作用,这些酶参与肽聚醣链的交联。此外,细胞壁合成抑制剂对革兰氏阳性细菌特别有效,因为它们的肽聚醣层较厚,这提供了更大的破坏目标。
头孢菌素
青霉素
氟喹诺酮类
大环内酯
碳青霉烯类
氨基糖苷类
其他的
青霉素占大部分市场份额
该报告根据药物类别提供了详细的市场细分和分析。这包括头孢菌素、青霉素、氟喹诺酮、大环内酯、碳青霉烯、氨基糖苷等。根据该报告,青霉素占了最大的份额。
青霉素是一类广泛使用的抗生素,属于 β-内酰胺类药物。它的作用是抑制细菌细胞壁的合成,导致细胞壁损伤和细菌死亡。它被认为是基本药物,并作为仿製药广泛使用。除此之外,它还广泛应用于各种医疗保健场所,例如医院、诊所和门诊场所。此外,青霉素的使用不断增加,因为它可以有效对抗各种细菌感染,也促进了市场的成长。
广效抗生素
窄谱抗生素
广谱抗生素占最大市场份额
该报告根据活动范围对市场进行了详细的细分和分析。这包括广谱抗生素和窄谱抗生素。根据该报告,广谱抗生素占了最大的份额。
广谱抗生素是一类对多种细菌(例如革兰氏阳性菌和革兰氏阴性菌)具有活性的抗生素。与此一致的是,与窄谱抗生素相比,广谱抗生素的使用越来越多,因为它们可以有效对抗更广泛的微生物,从而推动了市场的成长。除此之外,当致病细菌未知或感染涉及多种细菌时,广谱抗生素有助于治疗感染。适当使用广效抗生素可以最大限度地降低体内感染的风险。
口服
注射用
专题
其他的
注射剂占据细分市场的主导地位
该报告根据给药途径对市场进行了详细的细分和分析。这包括口服、肠胃外、局部用药等。根据该报告,注射剂占最大部分。
肠外抗生素经由消化道以外的途径给药,例如静脉注射(IV)、肌肉(IM)或皮下(SC)途径。这些途径可将药物绕过胃肠系统直接输送到血液或深层组织。此外,肠外抗生素可提供快速且可预测的药物吸收和即时的治疗效果。它们也适合胃肠功能受损的患者。除此之外,它还可以实现准确的剂量,并且在需要高药物浓度或无法口服给药的情况下特别有益。
医院
专科诊所
其他的
医院占最大市场份额
该报告提供了基于最终用户的详细市场细分和分析。这包括医院、专卖店等。报告称,医院占最大部分。
由于居住在医疗机构的患者数量不断增加,抗生素在医院中被广泛使用。对严重感染的患者使用抗生素。它们也在外科手术前施用,以降低细菌污染的风险。与此一致的是,个体术后预防中抗生素的使用不断增加,促进了市场的成长。除此之外,由于医院多重抗药性感染风险不断上升,抗生素的消耗量不断增加,也支撑了市场的成长。
北美洲
美国
加拿大
亚太
中国
日本
印度
韩国
澳洲
印尼
其他的
欧洲
德国
法国
英国
义大利
西班牙
俄罗斯
其他的
拉丁美洲
巴西
墨西哥
其他的
中东和非洲
亚太地区表现出明显的主导地位,占据最大的抗生素市场份额
该报告还对所有主要区域市场进行了全面分析,其中包括北美(美国和加拿大);亚太地区(中国、日本、印度、韩国、澳洲、印尼等);欧洲(德国、法国、英国、义大利、西班牙、俄罗斯等);拉丁美洲(巴西、墨西哥等);以及中东和非洲。报告称,亚太地区是最大的市场。
由于医疗基础设施的改善,亚太地区占据了最大的市场份额。与此一致的是,卫生条件差导致细菌感染的日益流行正在促进亚太地区市场的成长。除此之外,对能够有效对抗多重抗药性细菌的先进抗生素的需求不断增长,也支撑了市场的成长。此外,大量的仿製药製造商存在正在推动该地区市场的成长。
该行业的主要参与者正在投资研发(R&D)活动,以发现和开发新的抗生素,并专注于抗生素抗药性,扩大活动范围,并提高抗生素的功效和安全性。除此之外,他们还与研究机构、学术组织和政府机构合作,利用他们的专业知识,解决与抗生素开发相关的挑战,例如高成本和监管合规性。此外,抗生素公司正在积极推动抗生素管理计划,鼓励负责任和适当地使用抗生素,以避免过量和误用。此外,公司越来越多地进行临床试验并遵守安全性和有效性标准,以获得抗生素的监管批准。
艾尔建公司(艾伯维公司)
巴西利亚製药公司
葛兰素史克公司
强生公司
梅林塔疗法
默克公司
纳布里瓦治疗公司
帕拉泰克製药公司
辉瑞公司
赛诺菲公司
斯佩罗疗法
四相製药公司
2021年,诺华旗下山德士成功完成对葛兰素史克(GSK)头孢类抗生素业务的收购。此次收购为 Sandoz 提供了在 100 多个市场中三个知名品牌(Zinnat、Zinacef 和 Fortum)的权利。
2020年1月,默克宣布美国食品药物管理局(FDA)已批准DIFICID(R)(fidaxomicin)口服混悬液的新药申请(NDA)以及补充新药申请(sNDA)用于治疗6 个月及以上儿童艰难梭菌相关性腹泻(CDAD) 的DIFICID 片剂。
The global antibiotics market size reached US$ 49.4 Billion in 2022. Looking forward, IMARC Group expects the market to reach US$ 62.6 Billion by 2028, exhibiting a growth rate (CAGR) of 4.0% during 2022-2028. The growing prevalence of pneumonia, tuberculosis, and other infectious diseases among individuals, rising occurrence of antimicrobial resistance (AMR), and technological advancements in biotechnology and drug discovery techniques are some of the major factors propelling the market.
Antibiotics are a class of medications that are used to treat bacterial infections. They are widely available in various forms, such as pills, capsules, injections, creams, and ointments. They either kill bacteria or inhibit their growth to effectively eliminate infections. They target specific mechanisms or structures within bacterial cells and interfering with their vital functions and preventing their reproduction. Besides this, they assist in enhancing the immune system of individuals. As a result, antibiotics are utilized to treat various diseases, such as urinary tract infections (UTI), respiratory tract infections, skin infections, and certain sexually transmitted diseases among individuals.
At present, the increasing prevalence of numerous chronic diseases among the masses around the world is contributing to the growth of the market. Additionally, the wide availability of antibiotics through online and offline stores across the globe is strengthening the growth of the market. Apart from this, the growing demand for topical antibiotics, as they minimize the risk of surgical site infections among individuals, is positively influencing the market. Moreover, the increasing employment of antibiotics in livestock farming to safeguard animal health and welfare and support food safety is bolstering the growth of the market. In line with this, the rising demand for antibiotics among the geriatric population is supporting the growth of the market. Furthermore, the increasing consumer awareness about preventive healthcare measures is impelling the growth of the market.
Rising prevalence of infectious diseases
There is a rise in the prevalence of infectious diseases, such as pneumonia, tuberculosis, urinary tract infections (UTI), gastrointestinal infections, and sepsis, among the masses across the globe. People are increasingly suffering from these diseases due to inadequate sanitation, which contributes to the spread of bacterial infections. In addition, the emergence of drug-resistant bacteria is increasing the demand for antibiotics. There is a rise in the demand for effective antibiotics that assist in treating these infections. Antibiotics are specifically designed to target and eliminate bacterial infections. They effectively kill bacteria in the body and promote healing among individuals. Furthermore, antibiotics are used under the guidance of healthcare professionals to optimize patient outcomes.
Increasing occurrence of antimicrobial resistance (AMR)
There is a rise in the occurrence of antimicrobial resistance (AMR) across the globe, which is driving the antibiotics market. AMR occurs when bacteria, viruses, parasites, or fungi evolve and become resistant to the drugs used to treat them. It reduces the effectiveness of antibiotics and causes longer and more severe infections, increased healthcare costs, and high mortality rates among individuals. Overuse and misuse of antibiotics are contributing to the development of drug-resistant bacteria, which makes traditional antibiotics less effective. In addition, multidrug-resistant strains, such as Methicillin-resistant Staphylococcus aureus (MRSA) and Carbapenem-resistant Enterobacteriaceae (CRE), are more prevalent. This necessitates the development of new antibiotics or alternative treatments to combat these resistant strains.
Technological advancements in antibiotics
Innovations in biotechnology, molecular biology, and drug discovery techniques assist in improving the efficiency and effectiveness of antibiotic development. Genomics and high-throughput screening allow the identification of potential drug targets and the screening of large compound libraries. Moreover, computer-aided drug design enables the prediction of drug efficacy and optimizes antibiotic candidates. These technological advancements streamline the antibiotic discovery process and reduce the time and costs associated with traditional methods. Additionally, advancements in diagnostic techniques, such as rapid pathogen identification and susceptibility testing, assist in appropriate antibiotic selection and prescribing that provides enhanced patient outcomes. Furthermore, technological advancements aid in the development of new and more potent antibiotics to address infectious diseases and antimicrobial resistance.
IMARC Group provides an analysis of the key trends in each segment of the global antibiotics market report, along with forecasts at the global, regional and country levels from 2023-2028. Our report has categorized the market based on action mechanism, drug class, spectrum of activity, route of administration and end user.
Cell Wall Synthesis Inhibitors
Protein Synthesis Inhibitors
DNA Synthesis Inhibitors
RNA Synthesis Inhibitors
Mycolic Acid Inhibitors
Others
Cell wall synthesis inhibitors represent the largest market segment
The report has provided a detailed breakup and analysis of the market based on the action mechanism. This includes cell wall synthesis inhibitors, protein synthesis inhibitors, DNA synthesis inhibitors, RNA synthesis inhibitors, mycolic acid inhibitors, and others. According to the report, cell wall synthesis represented the largest segment.
Cell wall synthesis is a class of antibiotics that target the bacterial cell wall. These antibiotics interfere with the process of cell wall synthesis, which causes cell wall damage and eventual bacterial death. In addition, penicillin, cephalosporins, and carbapenems are some of the cell wall synthesis inhibitors. They work by inhibiting enzymes called penicillin-binding proteins (PBPs) that are involved in the cross-linking of peptidoglycan chains. Moreover, cell wall synthesis inhibitors are particularly effective against gram-positive bacteria due to their thicker peptidoglycan layer, which provides a greater target for disruption.
Cephalosporin
Penicillin
Fluoroquinolone
Macrolide
Carbapenem
Aminoglycoside
Others
Penicillin accounts for the majority of the market share
The report has provided a detailed breakup and analysis of the market based on the drug class. This includes cephalosporin, penicillin, fluoroquinolone, macrolide, carbapenem, aminoglycoside, and others. According to the report, penicillin represented the largest segment.
Penicillin is a widely used class of antibiotics that belongs to the beta-lactam drug class. It works by inhibiting the synthesis of bacterial cell walls that causes cell wall damage and bacterial death. It is considered an essential medicine and is widely available as generic drugs. Apart from this, it is widely used in various healthcare settings, such as hospitals, clinics, and outpatient settings. In addition, the rising utilization of penicillin, as it is effective against various bacterial infections, is contributing to the growth of the market.
Broad-Spectrum Antibiotics
Narrow-Spectrum Antibiotics
Broad-spectrum antibiotics hold the biggest market share
The report has provided a detailed breakup and analysis of the market based on the spectrum of activity. This includes broad-spectrum antibiotics and narrow-spectrum antibiotics. According to the report, broad-spectrum antibiotics represented the largest segment.
Broad-spectrum antibiotics are a class of antibiotics that exhibit activity against a wide range of bacteria, such as gram-positive and gram-negative bacteria. In line with this, the rising adoption of broader spectrum antibiotics, as they are effective against a broader range of microorganisms compared to narrow-spectrum antibiotics, is bolstering the growth of the market. Apart from this, broad-spectrum antibiotics assist in treating infections when the causative bacteria are unknown or when the infection involves multiple bacterial species. The appropriate use of broad-spectrum antibiotics minimizes the risks of infections in the body.
Oral
Parenteral
Topical
Others
Parenteral dominates the market segment
The report has provided a detailed breakup and analysis of the market based on the route of administration. This includes oral, parenteral, topical, and others. According to the report, parenteral represented the largest segment.
Parenteral antibiotics are administered via routes other than the digestive tract, such as intravenous (IV), intramuscular (IM), or subcutaneous (SC) routes. These routes allow for direct delivery of the medication into the bloodstream or deep tissues, bypassing the gastrointestinal system. In addition, parenteral antibiotics provide rapid and predictable drug absorption and immediate therapeutic effect. They are also suitable for patients with compromised gastrointestinal function. Apart from this, it allows for accurate dosing and is particularly beneficial in cases where high drug concentrations are needed or when oral administration is not possible.
Hospitals
Specialty Clinics
Others
Hospitals accounted for the largest market share
The report has provided a detailed breakup and analysis of the market based on the end user. This includes hospitals, specialty stores, and others. According to the report, hospitals represented the largest segment.
Antibiotics are widely consumed in hospitals due to the increased number of patients staying in this healthcare setting. Antibiotics are administered to patients admitted with severe infections. They are also administered before surgical procedures to reduce the risk of bacterial contamination. In line with this, the rising utilization of antibiotics among individual post-surgical prophylaxis is contributing to the growth of the market. Apart from this, the increasing consumption of antibiotics due to the rising risk of multidrug-resistant infections in hospitals is supporting the growth of the market.
North America
United States
Canada
Asia-Pacific
China
Japan
India
South Korea
Australia
Indonesia
Others
Europe
Germany
France
United Kingdom
Italy
Spain
Russia
Others
Latin America
Brazil
Mexico
Others
Middle East and Africa
Asia Pacific exhibits a clear dominance, accounting for the largest antibiotics market share
The report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, Asia Pacific represented the largest market.
Asia Pacific held the biggest market share due to the improved healthcare infrastructure. In line with this, the growing prevalence of bacterial infections to poor sanitation is contributing to the growth of the market in the Asia Pacific region. Apart from this, the increasing demand for advanced antibiotics that can effectively combat multidrug-resistant bacteria is supporting the growth of the market. Furthermore, the presence of a large number of generic drug manufacturers is propelling the growth of the market in the region.
Key players in the industry are investing in research and development (R&D) activities to discover and develop new antibiotics and focusing on antibiotic resistance, expanding the spectrum of activity, and improving the efficacy and safety profiles of antibiotics. Apart from this, they are engaging in collaboration with research institutions, academic organizations, and government bodies to leverage their expertise and address the challenges associated with antibiotic development, such as high costs and regulatory compliances. Moreover, antibiotic companies are actively promoting antibiotic stewardship programs that encourage responsible and appropriate use of antibiotics to avoid overdosage and misusage. Furthermore, companies are increasingly conducting clinical trials and adhering to safety and efficacy standards to obtain regulatory approvals for their antibiotics.
Allergan Plc (AbbVie Inc.)
Basilea Pharmaceutica AG
GlaxoSmithKline Plc
Johnson & Johnson
Melinta Therapeutics
Merck & Co. Inc.
Nabriva Therapeutics Plc
Paratek Pharmaceuticals Inc.
Pfizer Inc.
Sanofi SA
Spero Therapeutics
Tetraphase Pharmaceuticals
In 2021, Sandoz, a Novartis division, successfully completed the acquisition of GlaxoSmithKline's (GSK) cephalosporin antibiotics business. This acquisition provides them rights to three established brands (Zinnat, Zinacef and Fortum) in more than 100 markets to Sandoz.
In January 2020, Merck & Co. Inc. announced that U.S. Food and Drug Administration (FDA) has approved a New Drug Application (NDA) for DIFICID® (fidaxomicin) for oral suspension, and a supplemental New Drug Application (sNDA) for DIFICID tablets for the treatment of Clostridioides (formerly Clostridium) difficile-associated diarrhea (CDAD) in children aged six months and older.