市场调查报告书
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1422819
2024-2032 年聚乙二醇化蛋白质市场报告(按产品、蛋白质类型、应用、最终用户和地区)PEGylated Proteins Market Report by Product, Protein Type, Application, End User, and Region 2024-2032 |
2023年全球聚乙二醇化蛋白市场规模达13亿美元。展望未来, IMARC Group预计到2032年市场规模将达到28亿美元,2024-2032年复合年增长率(CAGR)为8.87%。慢性病盛行率的增加、癌症治疗中产品的广泛使用以及聚乙二醇化蛋白产品批准数量的不断增加是推动市场发展的一些关键因素。
聚乙二醇化蛋白质是透过与聚乙二醇 (PEG) 共价结合进行修饰的生物分子。它涉及聚乙二醇化技术,透过改变生物分子的物理和化学特性(例如其构象、静电结合和疏水性)来改善药物的药物动力学行为。聚乙二醇化蛋白广泛用于治疗应用,例如疫苗、荷尔蒙替代疗法、遗传性疾病、贫血和凝血障碍。它也用于治疗多种疾病的药物,包括肾臟病、多发性硬化症、血友病和癌症。聚乙二醇化蛋白质有助于延长半衰期,增加稳定性、溶解度和蛋白水解保护,减少肾臟排泄、免疫原性和毒性,并增强药物传递的功效。除此之外,聚乙二醇化蛋白质无毒性、水溶性、亲水性、非抗原性和非免疫原性。
全球肾臟疾病、自体免疫疾病、遗传性疾病、肝炎和类风湿性关节炎等慢性病盛行率的上升是推动市场成长的关键因素之一。聚乙二醇化蛋白广泛用于治疗发炎、向细胞传递校正基因、预防血栓、传递生长激素、预防慢性肾臟病的进展。与此一致的是,在癌症治疗中广泛使用产品将化疗药物直接输送到癌细胞并减少对健康细胞的副作用,有利于市场成长。除此之外,聚乙二醇化技术的各种改进,例如开发可以生产更小和更复杂分子的新聚乙二醇化方法,正在为市场成长提供动力。此外,广泛采用聚乙二醇化来提高集落刺激因子 (CSF) 的稳定性和半衰期,使它们作为治疗剂更有效,这也是另一种生长诱导因子。此外,与非蛋白质药物相比,蛋白质药物的采用率不断上升,其中聚乙二醇化增加了蛋白质的循环和半衰期,提高了其效率,正在推动市场成长。其他因素,包括聚乙二醇化蛋白产品批准数量的增加、生物技术和分子生物学工程领域的发展、聚乙二醇分子在生物製药中的整合及其相关优势、老年人口的增加以及各种政府倡议的实施製药业的监管标准预计将推动市场进一步成长。
The global PEGylated proteins market size reached US$ 1.3 Billion in 2023. Looking forward, IMARC Group expects the market to reach US$ 2.8 Billion by 2032, exhibiting a growth rate (CAGR) of 8.87% during 2024-2032. The increasing prevalence of chronic diseases, the widespread product utilization in cancer treatment, and the escalating number of product approvals for PEGylated proteins represent some of the key factors driving the market.
PEGylated proteins are biomolecules that have been modified by covalent conjugation with polyethylene glycol (PEG). It involves the PEGylation technique that improves the pharmacokinetic behavior of the medicine by altering the biological molecule's physical and chemical characteristics, such as its conformation, electrostatic binding, and hydrophobicity. PEGylated proteins are widely used in therapeutic applications, such as vaccines, hormone replacement therapy, genetic disorders, anemia, and blood clotting disorder. It is also used in various drugs for diseases, including kidney disease, multiple sclerosis, hemophilia, and cancers. PEGylated proteins help in the extension of half-life, increasing stability, solubility, and proteolytic protection, reducing renal excretion, immunogenicity, and toxicity, and enhancing the efficacy of drug delivery. Besides this, PEGylated proteins are non-toxic, water-soluble, hydrophilic, non-antigenic, and non-immunogenic.
The rising prevalence of chronic diseases, such as kidney ailments, autoimmune diseases, genetic disorders, hepatitis, and rheumatoid arthritis across the globe is one of the key factors driving the market growth. PEGylated proteins are widely used to treat inflammation, deliver corrective genes to cells, prevent blood clots, deliver growth hormones, and prevent the progression of chronic kidney disease. In line with this, the widespread product utilization in cancer treatment to deliver chemotherapy drugs directly to cancer cells and reduce the side effects on healthy cells is favoring the market growth. Apart from this, various improvements in the PEGylation technology, such as the development of new PEGylation methods that can produce smaller and more complex molecules, are providing an impetus to the market growth. Additionally, the widespread adoption of PEGylation to improve the stability and half-life of colony-stimulating factors (CSFs), making them more effective as therapeutic agents, is acting as another growth-inducing factor. Furthermore, the rising adoption of protein-based drugs over non-protein-based drugs wherein PEGylation increases the circulation and half-life of the proteins, improving its efficiency, is propelling the market growth. Other factors, including the increasing number of product approvals for PEGylated proteins, development in the field of biotechnology and molecular biology engineering, the integration of PEG molecules in biopharmaceuticals and the associated advantages, rising geriatric population, and the implementation of various government initiatives to increase regulatory standards in the pharmaceutical industry, are anticipated drive the market further toward growth.
IMARC Group provides an analysis of the key trends in each segment of the global PEGylated proteins market, along with forecasts at the global, regional, and country level from 2024-2032. Our report has categorized the market based on product, protein type, application, and end user.
Consumables
PEGylation Reagents
PEGylation Kits
Services
A detailed breakup and analysis of the PEGylated proteins market based on the product has also been provided in the report. This includes consumables (PEgylation reagents and PEgylation kits) and services. According to the report, consumables accounted for the largest market share.
Colony Stimulating Factors
Interferons
Erythropoietin
mAbs
Recombinant Factor VII
Others
The report has provided a detailed breakup and analysis of the PEGylated proteins market based on the protein type. This includes colony stimulating factors, interferons, erythropoietin, mAbs, recombinant factor VII and others. According to the report, colony stimulating factors represented the largest segment.
Cancer Treatment
Hepatitis
Chronic Kidney Diseases
Hemophilia
Multiple Sclerosis
Gastrointestinal Disorders
Others
A detailed breakup and analysis of the PEGylated proteins market based on the application has also been provided in the report. This includes cancer treatment, hepatitis, chronic kidney diseases, hemophilia, multiple sclerosis, gastrointestinal disorders, and others. According to the report, cancer treatment represented the largest segment.
Pharmaceutical and Biotechnology Companies
Contract Research Organizations
Academic and Research Institutes
The report has provided a detailed breakup and analysis of the PEGylated proteins market based on the end user. This includes pharmaceutical and biotechnology companies, contract research organizations, and academic and research institutes. According to the report, pharmaceutical and biotechnology companies represented the largest segment.
North America
United States
Canada
Europe
Germany
France
United Kingdom
Italy
Spain
Russia
Others
Asia Pacific
China
Japan
India
South Korea
Australia
Indonesia
Others
Latin America
Brazil
Mexico
Others
Middle East and Africa
The report has also provided a comprehensive analysis of all the major regional markets that include North America (the United States and Canada); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, North America was the largest market for PEGylated proteins. Some of the factors driving the North America PEGylated proteins market included the rising geriatric population, increasing prevalence of chronic diseases, and extensive research and development (R&D).
The report has also provided a comprehensive analysis of the competitive landscape in the global PEGylated proteins market. Detailed profiles of all major companies have also been provided. Some of the companies covered include Abcam plc, Biomatrik Inc., Creative PEGWorks, Iris Biotech GmbH, JenKem Technology USA Inc., Laysan Bio Inc., NOF America Corporation (NOF Corporation), Profacgen, Thermo Fisher Scientific Inc., etc.