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市场调查报告书
商品编码
1519389
2024-2032 年按技术、产品和服务、应用、最终用户和地区分類的高通量筛选市场报告High-throughput Screening Market Report by Technology, Products and Services, Applications, End User, and Region 2024-2032 |
IMARC Group年,全球高通量筛选市场规模达252亿美元。 3D细胞培养模型的采用增加、个人化药物筛选分析的需求不断增长以及基于CRISPR的筛选技术的应用不断增加是推动高通量筛选市场成长的一些关键因素。
主要市场驱动因素:越来越多地利用高温超导技术来最大限度地缩短药物製造所需的时间,这主要推动了市场的成长。此外,治疗各种危及生命的疾病的新药的开发也刺激了对高温超导技术的需求。
主要市场趋势:将人工智慧(AI)和机器学习(ML)等先进技术与高通量筛选相结合以促进自动化和快速资料处理是重要趋势之一,促进了市场的成长。
地理景观:高通量筛选市场预测报告提供了基于区域的详细市场区隔和分析。其中包括北美、亚太地区、欧洲、拉丁美洲、中东和非洲。由于高通量筛选的日益采用、研发支出的增加以及组合化学和基因组学领域的不断进步等因素,预计北美将在高通量筛选市场中占据重要的市场份额。
竞争格局:一些领先的高通量筛选市场公司包括安捷伦科技公司、Aurora Biomed Inc.、Axxam SpA、Beckman Coulter Inc.(丹纳赫公司)、Bio-RAD Laboratories Inc.、Charles River Laboratories International Inc.、康宁Incorporated、Luminex Corporation (DiaSorin)、Perkinelmer Inc.、Sygnature Discovery、Tecan Group Ltd. 和 Thermo Fisher Scientific 等。
挑战与机会:高通量筛选市场的挑战包括资料管理复杂性和对更多生理相关检测模型的需求,而机会则在于自动化、人工智慧和晶片器官系统等先进技术,以提高效率和预测筛选过程。
高温超导设施数量不断增加
用于治疗各种危及生命的疾病的新药的开发主要推动了市场的成长。此外,为了最大限度地减少药物製造所需时间而使用 HTS 的增加也促进了市场的成长。除此之外,高通量筛选(HTS)设施数量的不断增加也催化了高通量筛选市场的近期价格上涨。这些中心的显着优势之一是研究人员、科学家、研究人员等之间的知识共享。此外,美国国立卫生研究院 (NIH) 计画的欧洲对应计画(称为 EU-open-screen)为所有从事化学生物学的欧洲公司提供开放存取。高通量筛选(HTS)中心协会旨在提供有关药物或标靶或整个过程的有用资讯。因此,开放取用为知识共享提供了更好的平台,有助于加速药物开发进程,这可能会在未来几年推动高通量筛选市场份额。
新型分子的不断发展
各种传染病患者病率的上升正在推动新型分子和疫苗的开发,这反过来又为高通量筛检市场创造了积极的前景。此外,在药物製造过程中对各种药物和分子的精确和快速筛选的需求不断增加,导致越来越多地采用自动化高通量筛选技术。此外,由于高通量筛选方法具有高灵敏度、自动化、样品最小化以及检测低背景讯号的能力等各种优势,各种製药和生物製品公司越来越多地采用高通量筛选方法,这支撑了高通量筛选方法的发展。根据美国国会预算办公室公布的资料,2021年,全球製药业在研发上的支出接近2,000亿美元,而2019年为8,300万美元。为17.42 亿美元,而2020 年为13.48 亿美元。 此外,Bio-Rad Laboratories Inc. 2021 年的投资为8.796 亿美元,而2020 年为8.003 亿美元。量筛选分析中采用创新技术的能力,因而促进了市场成长。
技术进步
近年来,在机器人技术、自动化、资料分析和小型化不断创新的推动下,高通量筛选(HTS)技术取得了显着进展。此外,自动化和机器人技术的进步极大地提高了 HTS 工作流程的速度和效率。自动化液体处理系统、读板机和机器人平台现在可以高精度和高通量地执行重复性任务,从而减少了手动干预的需要。此外,各种领先的生物技术公司也在投资研发活动,以引入改进的高温超导方法,预计这将推动高通量筛选市场的收入。例如,2024 年2 月,生命科学分析技术领域的全球领导者SCIEX 在SLAS 2024 上推出了Echo MS+ 系统。相结合: SCIEX ZenoTOF 7600 或 Triple Quad 6500+ 系统透过强大的高通量筛选工作流程的扩展面板提供精确的定性和定量结果。
IMARC Group提供了全球高通量筛选市场报告每个细分市场的主要趋势分析,以及 2024 年至 2032 年全球、区域和国家层面的预测。我们的报告根据技术、产品和服务、应用程式以及最终用户对市场进行了分类。
超高通量筛选
基于细胞的检测
晶片实验室
无标籤技术
该报告基于该技术对市场进行了详细的细分和分析。这包括超高通量筛选、基于细胞的测定、晶片实验室和无标记技术。
高通量筛选市场概况表明,各种製药和生物技术公司越来越多地使用基于细胞的检测方法。高通量筛选中基于细胞的测定利用活细胞作为化合物测试的生物读数,能够以高通量方式评估候选药物对细胞功能、活力和表型的影响,通常用于药物发现和毒性筛选。萤光成像读板仪测定已成为最常用的基于细胞的测定,因为其结果可见并且能够以最小的体积进行测试。除此之外,超高通量筛选是最新技术,用于在更短的时间内提高产量。大多数公司正处于从 2D 细胞培养到 3D 细胞培养的过渡阶段,因为 3D 细胞在自然环境和其他细胞相关操作中进行测试时显示出更逼真的特性,有助于药物设计和发现。
仪器
试剂和试剂盒
服务
高通量筛选市场报告根据产品和服务对市场进行了详细的细分和分析。这包括仪器、试剂和套件以及服务。
高通量筛选依赖专用仪器,例如自动液体处理机、读板器和机器人平台。这些仪器能够快速处理、分配和分析微孔板形式的样品,从而提高筛选实验的效率和通量。而用于高通量筛选的试剂和试剂盒包括化合物库、生化分析以及检测试剂,例如萤光探针或酵素底物。这些经过最佳化,可与自动化系统和小型化测定格式相容,从而可以根据特定的生物标靶或途径筛选大型化合物库。
目标识别和验证
初级和次级筛选
毒理学评估
其他的
该报告根据应用程式提供了详细的市场细分和分析。这包括目标识别和验证、初步和二次筛选、毒理学评估等。
目标识别和验证涉及识别和验证与疾病或生物过程有关的分子目标(例如蛋白质、基因或细胞途径)。透过基因组学、蛋白质组学和生物资讯学等各种方法,识别并验证潜在目标,以确保其相关性和可拖曳性以进行进一步研究。而在初级和二级筛选中,针对特定标靶或生物测定对大型化合物库进行测试,以识别显示活性或调节的初始命中。该方法涉及对命中化合物进行更详细的表征,以确认其活性、选择性和效力。初级和次级筛选通常包括剂量反应研究、反筛选和次级测定,以验证命中并优先考虑先导化合物优化和临床前开发。
製药和生物技术公司
学术和政府机构
合约研究组织
其他的
该报告提供了基于最终用户的详细市场细分和分析。这包括製药和生物技术公司、学术和政府机构、合约研究组织等。
根据IMARC的高通量筛选市场统计数据,製药公司和政府组织的研发支出最近一直在增加,预计这将在预测期内推动市场成长。例如,全球领先的生命科学和诊断创新企业丹纳赫公司(Danaher Corporation) 2021 年的研发投资为17.42 亿美元,而2020 年为13.48 亿美元。美元。
北美洲
美国
加拿大
亚太
中国
日本
印度
韩国
澳洲
印尼
其他的
欧洲
德国
法国
英国
义大利
西班牙
俄罗斯
其他的
拉丁美洲
巴西
墨西哥
其他的
中东和非洲
市场研究报告还对所有主要区域市场进行了全面分析,其中包括北美(美国和加拿大);欧洲(德国、法国、英国、义大利、西班牙、俄罗斯等);亚太地区(中国、日本、印度、韩国、澳洲、印尼等);拉丁美洲(巴西、墨西哥等);以及中东和非洲。
由于高通量筛选的日益采用、研发支出的增加以及组合化学和基因组学领域的不断进步等多种因素,预计北美将在高通量筛选市场中占据重要的市场份额。除此之外,该地区知名市场参与者的存在也对高通量筛选市场前景产生正面影响。例如,2021 年8 月,Becton、Dickinson 和Company 推出了一种新型全自动高通量诊断系统,使用机器人技术和样本管理软体演算法,为核心实验室和其他集中实验室的传染病分子检测自动化设定了新标准在美国。此次发布使得 BD Onclarity HPV Assay 具有针对 BD COR 系统的扩展基因分型,可供高通量实验室处理美国大多数持续感染人类乳突病毒 (HPV) 的子宫颈癌筛检标本。
The global high-throughput screening market size reached US$ 25.2 Billion in 2023. Looking forward, IMARC Group expects the market to reach US$ 49.0 Billion by 2032, exhibiting a growth rate (CAGR) of 7.5% during 2024-2032. The increased adoption of 3D cell culture models, growing demand for personalized medicine screening assays, and rising application of CRISPR-based screening techniques are some of the key factors driving high-throughput screening market growth.
Major Market Drivers: The increasing utilization of HTS for minimizing the time required for manufacturing a drug is primarily driving the growth of the market. Furthermore, the development of new medicines for treating various life-threatening diseases is also catalyzing the demand for HTS techniques.
Key Market Trends: Integration of advanced technologies, such as artificial intelligence (AI) and machine learning (ML) with high-throughput screening to facilitate automation and fast data processing is one of the significant trends, augmenting the growth of the market.
Geographical Landscape: The high-throughput screening market forecast report has provided a detailed breakup and analysis of the market based on the region. This includes North America, Asia Pacific, Europe, Latin America, and Middle East and Africa. North America is expected to hold a significant market share in the high-throughput screening market owing to factors such as the increasing adoption of high-throughput screening, rising research and development expenditure, and the growing advances in combinatorial chemistry and the field of genomics.
Competitive Landscape: Some of the leading high-throughput screening market companies include Agilent Technologies Inc., Aurora Biomed Inc., Axxam S.p.A, Beckman Coulter Inc. (Danaher Corporation), Bio-RAD Laboratories Inc., Charles River Laboratories International Inc. Corning Incorporated, Luminex Corporation (DiaSorin), Perkinelmer Inc., Sygnature Discovery, Tecan Group Ltd., and Thermo Fisher Scientific, among many others.
Challenges and Opportunities: Challenges in the high-throughput screening market include data management complexities and the need for more physiologically relevant assay models, while opportunities lie in advancing technologies like automation, artificial intelligence, and organ-on-a-chip systems for more efficient and predictive screening processes.
Increasing Number of HTS Facilities
The development of new medicines for treating various life-threatening diseases is primarily driving the growth of the market. Furthermore, the rise in the utilization of HTS for minimizing the time required for manufacturing a drug is also contributing to the market growth. In addition to this, the escalating number of high-throughput screening (HTS) facilities is also catalyzing the high-throughput screening market's recent prices. One of the significant advantages of these centers is knowledge sharing among investigators, scientists, researchers, etc. For instance, the Columbia Genome Center offers high-quality molecular screening services for investigators throughout the Columbia University research community. Also, the European counterpart of the National Institutes of Health (NIH) program, known as EU-open-screen, provides open access to all European companies engaged in chemical biology. The association of high-throughput screening (HTS) centers is intended to provide useful information about the drug or target or the entire process. Thus, open access provides a better platform for knowledge sharing and can help accelerate the drug development process, which may drive the high-throughput screening market share in the coming years.
Rising Development of Novel Molecules
The rising prevalence of various infectious diseases is prompting the development of novel molecules and vaccines, which in turn is creating a positive outlook for the high-throughput screening market. Moreover, the escalating need for precise and quick screening of various drugs and molecules during the manufacturing of a drug is resulting in an increased adoption of automated high-throughput screening techniques. Furthermore, various pharmaceutical and biologic firms are increasingly adopting high-throughput screening methods on account of their various advantages, such as high sensitivity, automation, minimization of the sample, and the ability to detect low background signals, which is bolstering the high-throughput screening market demand. According to the data published by the Congressional Budget Office, in 2021, it was observed that pharmaceutical industries spent nearly US$ 200 Billion on research and development in 2020 globally, compared to US$ 83 Million in 2019. Similarly, Danaher Corporation invested US$ 1,742 Million in its research and development in 2021, as compared to US$ 1,348 Million in 2020. In addition, Bio-Rad Laboratories Inc. invested US$ 879.6 Million in 2021 as compared to US$ 800.3 Million in 2020. Thus, the increasing investment in research and development by the companies further increases their capabilities to adopt innovative technologies in high throughput screening assays, thereby increasing the market growth.
Technological Advancements
High-throughput screening (HTS) techniques have seen significant advancements in recent years, driven by the continuous innovations in robotics, automation, data analysis, and miniaturization. Moreover, advances in automation and robotics are extensively increasing the speed and efficiency of HTS workflows. Automated liquid handling systems, plate readers, and robotic platforms can now perform repetitive tasks with high precision and throughput, reducing the need for manual intervention. Additionally, various leading biotech companies are also investing in research and development activities to introduce improved HTS methods which are anticipated to propel the high-throughput screening market revenue. For instance, in February 2024, SCIEX, a global leader in life science analytical technologies, launched the Echo MS+ system at SLAS 2024. The system couples proprietary Acoustic Ejection Mass Spectrometry technology and Open Port Interface (OPI) sampling with the capabilities of either the SCIEX ZenoTOF 7600 or Triple Quad 6500+ system to deliver precise qualitative and quantitative results through an expanded panel of robust high-throughput screening workflows.
IMARC Group provides an analysis of the key trends in each sub-segment of the global high-throughput screening market report, along with forecasts at the global, regional, and country levels from 2024-2032. Our report has categorized the market based on technology, products and services, applications, and end user.
Ultra-High-Throughput Screening
Cell-Based Assays
Lab-on-a-Chip
Label-Free Technology
The report has provided a detailed breakup and analysis of the market based on the technology. This includes ultra-high throughput screening, cell-based assays, lab-on-a-chip, and label-free technology.
The high-throughput screening market overview indicates that cell-based assays are increasingly being used by various pharmaceutical and biotech companies. Cell-based assays in high-throughput screening utilize live cells as the biological readout for compound testing, enabling the evaluation of drug candidates' effects on cellular function, viability, and phenotype in a high-throughput manner, often employed in drug discovery and toxicity screening. Fluorometric imaging plate reader assays have become the most used cell-based assays owing to visible results and their ability to test with the smallest of volumes. Besides this, ultra-high-throughput screening is the latest technology and is used for increased output in less time. A majority of companies are in a transition phase from 2D-cell cultures to 3D-cell cultures as 3D cells show more lifelike properties while testing in the natural environment and other cell-related manipulations, aided for drug design and discovery.
Instruments
Reagents and Kits
Services
The high-throughput screening market report has provided a detailed breakup and analysis of the market based on the products and services. This includes instruments, reagents and kits, and services.
High-throughput screening relies on specialized instruments, such as automated liquid handlers, plate readers, and robotic platforms. These instruments enable the rapid handling, dispensing, and analysis of samples in microplate formats, thereby increasing the efficiency and throughput of screening experiments. Whereas reagents and kits that are used in high-throughput screening include compound libraries, biochemical assays, and detection reagents such as fluorescent probes or enzyme substrates. These are optimized for compatibility with automated systems and miniaturized assay formats, allowing for the screening of large compound libraries against specific biological targets or pathways.
Target Identification and Validation
Primary and Secondary Screening
Toxicology Assessment
Others
The report has provided a detailed breakup and analysis of the market based on the application. This includes target identification and validation, primary and secondary screening, toxicology assessment and others.
Target identification and validation involves identifying and validating molecular targets (such as proteins, genes, or cellular pathways) that are implicated in a disease or biological process. Through various methods, including genomics, proteomics, and bioinformatics, potential targets are identified and then validated to ensure their relevance and draggability for further investigation. Whereas in primary and secondary screening large libraries of compounds are tested against a specific target or biological assay to identify initial hits that show activity or modulation. This method involves a more detailed characterization of hit compounds to confirm their activity, selectivity, and potency. Primary and secondary screening typically includes dose-response studies, counter-screens, and secondary assays to validate hits and prioritize them for lead optimization and preclinical development.
Pharmaceutical and Biotechnology Firms
Academic and Government Institutes
Contract Research Organizations
Others
The report has provided a detailed breakup and analysis of the market based on the end user. This includes pharmaceutical and biotechnology firms, academic and government institutes, contract research organizations, and others.
According to high-throughput screening market statistics by IMARC, the spending on research and development (R&D) by both pharmaceutical companies and government organizations has been increasing recently, which is anticipated to drive market growth over the forecast period. For instance, Danaher Corporation, a leading global life sciences and diagnostics innovator, invested US$ 1,742 Million in its research and development in 2021, as compared to US$ 1,348 Million in 2020. In addition, Bio-Rad Laboratories Inc. invested US$ 879.6 Million in 2021 as compared to US$ 800.3 Million in 2020. Thus, the huge investment by pharmaceuticals, biotech firms, and government institutions will continue to drive the market growth.
North America
United States
Canada
Asia-Pacific
China
Japan
India
South Korea
Australia
Indonesia
Others
Europe
Germany
France
United Kingdom
Italy
Spain
Russia
Others
Latin America
Brazil
Mexico
Others
Middle East and Africa
The market research report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa.
North America is expected to hold a significant market share in the high-throughput screening market owing to various factors such as the increasing adoption of high-throughput screening, rising research and development expenditure, and the growing advances in combinatorial chemistry and the field of genomics. In addition to this, the presence of prominent market players in the region is also positively impacting the high-throughput screening market outlook. For instance, in August 2021, Becton, Dickinson, and Company launched a new, fully automated high-throughput diagnostic system using robotics and sample management software algorithms to set a new standard in automation for infectious disease molecular testing in core laboratories and other centralized laboratories in the United States. This launch made BD Onclarity HPV Assay with extended genotyping for the BD COR System available to the high-throughput labs for processing most cervical cancer screening specimens in the United States with persistent infection with human papillomavirus (HPV).
Agilent Technologies Inc.
Aurora Biomed Inc.
Axxam S.p.A
Beckman Coulter Inc. (Danaher Corporation)
Bio-RAD Laboratories Inc.
Charles River Laboratories International Inc.
Corning Incorporated
Luminex Corporation (DiaSorin)
Perkinelmer Inc.
Sygnature Discovery
Tecan Group Ltd
Thermo Fisher Scientific
(Please note that this is only a partial list of the key players, and the complete list is provided in the report.)
April 2024: Gordian Biotechnology introduced a high-throughput in vivo screening platform to discover therapies and better predict human outcomes for age-related diseases.
April 2024: Metrion Biosciences Limited and Enamine Ltd., announced that Metrion has enhanced its High Throughput Screening (HTS) services with the addition of access to Enamine's compound libraries.
February 2024: SCIEX, a global leader in life science analytical technologies, launched the Echo MS+ system at SLAS 2024. The system couples proprietary Acoustic Ejection Mass Spectrometry technology and Open Port Interface (OPI) sampling with the capabilities of either the SCIEX ZenoTOF 7600 or Triple Quad 6500+ system to deliver precise qualitative and quantitative results, through an expanded panel of robust high-throughput screening workflows.