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2024-2032 年按产品、类型、方法、最终用户和地区分類的核酸分离和纯化市场报告Nucleic Acid Isolation and Purification Market Report by Product, Type, Method, End User, and Region 2024-2032 |
IMARC Group年,全球核酸分离纯化市场规模达53亿美元。分子诊断和研究、自动化和高通量技术进步的需求不断增长、COVID-19 大流行的影响以及医疗保健以外的应用扩展是推动市场的一些主要因素。
核酸分离和纯化是指从各种生物样本中分离和精製脱氧核糖核酸(DNA)或核糖核酸(RNA)分子的过程。这一重要步骤在分子生物学和诊断学中至关重要。样本通常在分离阶段裂解以释放核酸。随后,纯化涉及去除污染物、蛋白质和其他细胞成分,以产生适合下游应用的纯核酸,包括聚合酶炼式反应 (PCR)、定序或分析。通常使用苯酚-氯仿萃取、管柱层析或基于磁珠的方法等技术。
由于医疗保健、生物技术和製药等各个领域对分子诊断和基因研究的需求不断增长,全球核酸分离和纯化市场正在经历强劲成长。与此一致,随着个人化医疗和基因组学研究的重要性不断上升,对高效核酸分离和纯化技术的需求激增,为市场扩张创造了积极的前景。此外,自动化和高通量技术的显着进步简化了这些流程,减少了体力劳动并提高了效率,从而促进了市场成长。除此之外,由于PCR检测的广泛使用,COVID-19大流行推动了对核酸分离和纯化产品的需求,从而有助于市场扩张。此外,市场参与者为提高产品性能和扩大应用领域而增加的研发投资也促进了市场的成长。
对分子诊断和基因研究的需求不断增加
推动核酸分离和纯化市场的主要因素之一是对分子诊断和基因研究不断增长的需求。在医疗保健领域,人们越来越重视个人化医疗,即利用遗传资讯为个别患者量身定制治疗方案。这一趋势刺激了对高效、准确的核酸分离和纯化方法的需求。同时,研究人员和临床医生需要高品质的 DNA 和 RNA 样本来进行各种分子测试,包括 PCR、定序和基因表现分析。同样,生物技术和製药行业严重依赖核酸分离和纯化来开发和测试新药、疫苗和疗法。多个产业的持续需求是市场成长的关键驱动力。
自动化和高通量技术的进步
推动市场成长的另一个重要因素是核酸分离和纯化过程中自动化和高通量技术的不断进步。自动化系统和机器人平台的开发是为了简化和标准化这些程序,减少对体力劳动的依赖,并最大限度地降低污染风险。与此一致的是,高通量仪器和方法使研究人员能够同时处理大量样品,从而提高效率和可扩展性。这些技术创新节省了时间并提高了核酸分离和纯化的再现性和一致性,使其对寻求更高通量和更高精度的实验室和研究机构越来越有吸引力。
COVID-19 大流行的影响
持续的COVID-19大流行对核酸分离纯化产业产生了重大影响。基于 PCR 的检测是诊断 COVID-19 的重要工具,在很大程度上依赖病毒 RNA 的分离和纯化。对 COVID-19 检测的需求激增,以及对研究和监测的需求,导致核酸分离和纯化产品的使用量空前增加。市场参与者透过扩大生产规模和开发用于 SARS-CoV-2 检测的专用试剂盒和试剂,迅速适应了这一需求。儘管大流行的动态可能会随着时间的推移而发生变化,但人们对强有力的核酸分离和纯化过程在传染病控制和研究中的重要性的认识不断提高,预计将对市场的成长产生持久影响。
The global nucleic acid isolation and purification market size reached US$ 5.3 Billion in 2023. Looking forward, IMARC Group expects the market to reach US$ 10.2 Billion by 2032, exhibiting a growth rate (CAGR) of 7.4% during 2024-2032. The increasing demand in molecular diagnostics and research, automation and high-throughput technology advancements, the impact of the COVID-19 pandemic, and expanding applications beyond healthcare are some of the major factors propelling the market.
Nucleic acid isolation and purification refers to the processes employed in separating and refining deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) molecules from various biological samples. This essential step is crucial in molecular biology and diagnostics. The sample is typically lysed in the isolation phase to release nucleic acids. Subsequently, purification involves removing contaminants, proteins, and other cellular components to yield pure nucleic acids suitable for downstream applications, including polymerase chain reaction (PCR), sequencing, or analysis. Techniques such as phenol-chloroform extraction, column chromatography, or magnetic bead-based methods are commonly used.
The global nucleic acid isolation and purification market is experiencing robust growth driven by the increasing demand for molecular diagnostics and genetic research across various fields, including healthcare, biotechnology, and pharmaceuticals. In line with this, as the importance of personalized medicine and genomics research continues to rise, there is a surging need for efficient nucleic acid isolation and purification techniques, creating a positive outlook for market expansion. Moreover, significant advancements in automation and high-throughput technologies have streamlined these processes, reducing manual labor and improving efficiency, thereby fostering market growth. In addition to this, the COVID-19 pandemic has impelled the demand for nucleic acid isolation and purification products due to the extensive use of PCR-based testing, thereby aiding in market expansion. Furthermore, rising investments in research and development (R&D) by market players to enhance product performance and expand application areas are contributing to the market's growth.
Increasing demand for molecular diagnostics and genetic research
One of the primary factors driving the nucleic acid isolation and purification market is the growing demand for molecular diagnostics and genetic research. In the healthcare sector, there is a rising emphasis on personalized medicine, where genetic information is used to tailor treatments to individual patients. This trend has spurred the need for efficient and accurate nucleic acid isolation and purification methods. Concurrent with this, researchers and clinicians require high-quality DNA and RNA samples to perform various molecular tests, including PCR, sequencing, and gene expression analysis. Similarly, the biotechnology and pharmaceutical industries heavily rely on nucleic acid isolation and purification to develop and test new drugs, vaccines, and therapies. This sustained demand across multiple sectors is a key driving force behind the market's growth.
Advancements in automation and high-throughput technologies
Another significant factor fueling market growth is the continuous advancement of automation and high-throughput technologies in nucleic acid isolation and purification processes. Automation systems and robotic platforms have been developed to streamline and standardize these procedures, reducing the dependence on manual labor and minimizing the risk of contamination. In line with this, High-throughput instruments and methods enable researchers to process a larger number of samples simultaneously, improving efficiency and scalability. These technological innovations save time and enhance the reproducibility and consistency of nucleic acid isolation and purification, making them increasingly attractive to laboratories and research facilities seeking higher throughput and improved precision.
Impact of the COVID-19 pandemic
The ongoing COVID-19 pandemic has exerted a significant influence on the nucleic acid isolation and purification industry. PCR-based testing, a crucial tool for diagnosing COVID-19, relies heavily on the isolation and purification of viral RNA. The surge in demand for COVID-19 testing, along with the need for research and surveillance, has led to an unprecedented uptick in the utilization of nucleic acid isolation and purification products. Market players quickly adapted to meet this demand by scaling up production and developing specialized kits and reagents for SARS-CoV-2 detection. Although the pandemic's dynamics may change over time, the heightened awareness of the importance of robust nucleic acid isolation and purification processes in infectious disease control and research is expected to have a lasting impact on the market's growth.
IMARC Group provides an analysis of the key trends in each segment of the global nucleic acid isolation and purification market report, along with forecasts at the global, regional, and country levels for 2024-2032. Our report has categorized the market based on product, type, method, and end user.
Kits and Reagents
Instruments
Kits and reagents dominate the market
The report has provided a detailed breakup and analysis of the market based on the product. This includes kits and reagents, and instruments. According to the report, kits and reagents represented the largest segment.
The demand for nucleic acid isolation and purification products, specifically kits and reagents, is propelled by the expanding application of nucleic acid-based techniques in the fields of forensic science and environmental monitoring. These areas increasingly rely on nucleic acid isolation and purification for DNA profiling, crime scene analysis, and identifying microbial contaminants. Additionally, the growing interest in agriculture and food safety drives the need for genetic testing and traceability, spurring demand for nucleic acid products. Apart from this, the emergence of innovative and specialized kits and reagents tailored to specific applications, such as RNA sequencing or viral RNA extraction, is attracting researchers and diagnostic labs, strengthening the market growth. Furthermore, the continuous development of user-friendly, cost-effective, and high-performance products accelerate the utilization of nucleic acid isolation and purification kits and reagents across various industries, providing impetus to the market growth.
Plasmid DNA Isolation and Purification
Total RNA Isolation and Purification
Circulating Nucleic Acid Isolation and Purification
Genomic DNA Isolation and Purification
Messenger RNA Isolation and Purification
microRNA Isolation and Purification
PCR Cleanup
Others
Plasmid DNA isolation and purification holds the largest share in the market
A detailed breakup and analysis of the market based on the type has also been provided in the report. This includes plasmid DNA isolation and purification, total RNA isolation and purification, circulating nucleic acid isolation and purification, genomic DNA isolation and purification, messenger RNA isolation and purification, microRNA isolation and purification, PCR cleanup, and others. According to the report, plasmid DNA isolation and purification accounted for the largest market share.
The increasing importance of plasmid DNA in biotechnology and gene therapy applications is driving the demand for plasmid DNA isolation and purification. Plasmids are vital tools for genetic engineering, gene expression, and recombinant protein production, making them indispensable in the biopharmaceutical industry. Moreover, the rise of gene and cell therapies has created a surge in the demand for high-quality plasmid DNA for vector construction and therapeutic gene delivery, aiding in market expansion. Concurrent with this, the expanding field of synthetic biology, where custom-designed plasmids are employed to create novel biological systems, fuels the need for efficient plasmid DNA isolation and purification methods. The development of advanced purification techniques, such as chromatography and membrane-based systems, further enhances the purity and yield of plasmid DNA, making them essential components in the biotechnology and medical sectors and driving market demand.
Column-Based Isolation and Purification
Magnetic Bead-Based Isolation and Purification
Reagent-Based Isolation and Purification
Others
Column-based isolation and purification dominates the market
The report has provided a detailed breakup and analysis of the market based on the method. This includes column-based isolation and purification, magnetic bead-based isolation and purification, reagent-based isolation and purification, and others. According to the report, column-based isolation and purification represented the largest segment.
The demand for nucleic acid isolation and purification, specifically through column-based methods, is fueled by the preference for column-based techniques in research and clinical laboratories due to their efficiency, simplicity, and scalability. These methods offer researchers a reliable and convenient means of isolating and purifying nucleic acids with high purity and yield. Additionally, the versatility of column-based systems enables their use across a wide range of applications, from fundamental research to diagnostics, impelling the market growth. Moreover, advancements in column technology, such as improved matrix materials and design, have led to enhanced performance and faster processing times, making them increasingly attractive to users seeking rapid and consistent results. Furthermore, the stringent quality control requirements in genomics, molecular diagnostics, and pharmaceuticals have led to the continued adoption of column-based nucleic acid isolation and purification methods, driving sustained demand in the market.
Hospitals and Diagnostic Centers
Academic and Government Research Institutes
Pharmaceutical and Biotechnology Companies
Contract Research Organizations
Others
Hospitals and diagnostic centers hold the largest share in the market
A detailed breakup and analysis of the market based on the end user has also been provided in the report. This includes hospitals and diagnostic centers, academic and government research institutes, pharmaceutical and biotechnology companies, contract research organizations, and others. According to the report, hospitals and diagnostic centers accounted for the largest market share.
The demand for nucleic acid isolation and purification products, particularly among hospital and diagnostic end-users, is primarily driven by the growing significance of molecular diagnostics in healthcare. Hospitals and diagnostic laboratories increasingly rely on nucleic acid-based tests to accurately diagnose various diseases, including infectious diseases, cancer, and genetic disorders. This has resulted in a consistent demand for high-quality DNA and RNA samples, thus fueling the need for efficient nucleic acid isolation and purification methods. Additionally, the rapid adoption of point-of-care testing and the emergence of novel diagnostic assays have amplified the demand for streamlined nucleic acid extraction processes that can be integrated into diagnostic workflows, thereby bolstering the market growth. As precision medicine gains prominence in patient care, hospitals are also utilizing nucleic acid purification techniques for personalized treatment strategies, propelling the market forward.
North America
United States
Canada
Asia-Pacific
China
Japan
India
South Korea
Australia
Indonesia
Others
Europe
Germany
France
United Kingdom
Italy
Spain
Russia
Others
Latin America
Brazil
Mexico
Others
Middle East and Africa
North America exhibits a clear dominance, accounting for the largest nucleic acid isolation and purification market share
The market research report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, North America accounted for the largest market share.
North America's well-established and advanced healthcare infrastructure, along with a robust presence of pharmaceutical and biotechnology companies, has created a significant demand for nucleic acid isolation and purification products. As precision medicine and genetic research gain momentum, the need for high-quality DNA and RNA samples in North America continues to rise, driving the market's growth. In addition to this, the increasing prevalence of chronic conditions such as cancer, infectious diseases, and genetic disorders in the region has led to an elevated demand for molecular diagnostics, further boosting the requirement for efficient nucleic acid isolation and purification methods. Furthermore, North America has been at the forefront of research and development in genomics, gene therapy, and biopharmaceuticals, contributing to the adoption of advanced purification techniques and specialized kits and reagents, thus playing a pivotal role in driving market expansion in the region.
The competitive landscape of the global nucleic acid isolation and purification market is characterized by intense rivalry among key players and a dynamic ecosystem of companies providing an array of products and services. Prominent companies dominate the market with their extensive product portfolios, global reach, and continuous investments in research and development. Additionally, a multitude of smaller and niche players cater to specialized segments and applications within the market, providing innovative solutions and fostering competition. Collaborations and partnerships between market players and research institutions are commonplace, further intensifying competition and driving innovation. As the market continues to expand, new entrants are attracted to its potential, contributing to a dynamic competitive landscape.
Abcam plc
Agilent Technologies Inc.
Bio-Rad Laboratories Inc.
Illumina Inc.
Macherey-Nagel Gmbh & Co. Kg
New England Biolabs
Norgen Biotek Corp.
Omega Bio-Tek Inc.
Promega Corporation
Qiagen
Roche Molecular Systems Inc. (F. Hoffmann-La Roche AG)
Takara Bio Inc. (Takara Holdings Inc.)
Thermo Fisher Scientific Inc.
In August 2023, Abcam plc announced that it has entered into a definitive agreement pursuant to which Danaher Corporation will acquire all of the outstanding shares of Abcam for $24.00 per share in cash.
In July 2023, Illumina Inc. announced the launch of the latest version of DRAGEN(TM) software for analysis of next-generation sequencing data. DRAGEN 4.2 expands accuracy, flexibility, and scalability to enable efficient workflows and extract meaningful insights from genomic data.
In January 2023, Agilent Technologies Inc. announced a $725 million investment to expand the manufacturing capacity of therapeutic nucleic acids in response to the strong demand for the company's high-quality active pharmaceutical ingredients (API).