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2024-2032 年按作用机制、药物类别、活性谱、给药途径、最终用户和地区分類的抗生素市场报告Antibiotics Market Report by Action Mechanism, Drug Class, Spectrum of Activity, Route of Administration, End User, and Region 2024-2032 |
2023年全球抗生素市场规模达514亿IMARC Group。肺炎、结核病和其他传染病在个体中的盛行率不断上升,抗菌素抗药性(AMR)的发生率不断上升,以及生物技术和药物发现技术的进步是推动市场的一些主要因素。
抗生素是一类用于治疗细菌感染的药物。它们以多种形式广泛存在,例如丸剂、胶囊、注射剂、乳膏和软膏。它们要么杀死细菌,要么抑制其生长,以有效消除感染。它们针对细菌细胞内的特定机製或结构,干扰其重要功能并阻止其繁殖。除此之外,它们还有助于增强个体的免疫系统。因此,抗生素被用来治疗各种疾病,例如泌尿道感染(UTI)、呼吸道感染、皮肤感染和某些个别性传染病。
目前,世界各地群众中多种慢性病的盛行率不断上升,推动了市场的成长。此外,抗生素透过全球线上和线下商店的广泛供应正在加强市场的成长。除此之外,对局部抗生素的需求不断增长,因为它们可以最大限度地降低个人手术部位感染的风险,并且正在对市场产生积极影响。此外,为了保障动物健康和福利以及支持食品安全,畜牧业中越来越多地使用抗生素,这也促进了市场的成长。与此一致的是,老年人口对抗生素的需求不断增长正在支持市场的成长。此外,消费者对预防保健措施的认识不断增强正在推动市场的成长。
传染病病率上升
全球范围内,肺炎、结核、泌尿道感染(UTI)、胃肠道感染和败血症等传染病的盛行率呈上升趋势。由于卫生设施不足,导致细菌感染传播,人们越来越多地遭受这些疾病的困扰。此外,抗药性细菌的出现也增加了对抗生素的需求。对有助于治疗这些感染的有效抗生素的需求不断增加。抗生素是专门针对和消除细菌感染而设计的。它们能有效杀死体内的细菌并促进个体癒合。此外,抗生素是在医疗保健专业人员的指导下使用的,以优化患者的治疗效果。
抗菌素抗药性 (AMR) 的发生率增加
全球抗生素抗药性(AMR)的发生率不断上升,推动了抗生素市场的发展。当细菌、病毒、寄生虫或真菌进化并对治疗它们的药物产生抗药性时,就会发生抗菌素抗药性。它降低了抗生素的有效性,导致感染时间更长、更严重、医疗费用增加以及个人死亡率高。抗生素的过度使用和滥用会导致抗药性细菌的产生,从而降低传统抗生素的效果。此外,多重抗药性菌株,如抗甲氧西林金黄色葡萄球菌(MRSA)和抗碳青霉烯类肠桿菌(CRE)也更为常见。这就需要开发新的抗生素或替代疗法来对抗这些抗药性菌株。
抗生素技术进步
生物技术、分子生物学和药物发现技术的创新有助于提高抗生素开发的效率和有效性。基因组学和高通量筛选可以识别潜在的药物标靶并筛选大型化合物库。此外,电脑辅助药物设计可以预测药物疗效并优化候选抗生素。这些技术进步简化了抗生素的发现过程,并减少了与传统方法相关的时间和成本。此外,诊断技术的进步,例如快速病原体识别和药物敏感性测试,有助于适当的抗生素选择和处方,从而改善患者的治疗效果。此外,技术进步有助于开发新的、更有效的抗生素来解决传染病和抗菌素抗药性。
The global antibiotics market size reached US$ 51.4 Billion in 2023. Looking forward, IMARC Group expects the market to reach US$ 70.7 Billion by 2032, exhibiting a growth rate (CAGR) of 3.5% during 2024-2032. The growing prevalence of pneumonia, tuberculosis, and other infectious diseases among individuals, rising occurrence of antimicrobial resistance (AMR), and technological advancements in biotechnology and drug discovery techniques are some of the major factors propelling the market.
Antibiotics are a class of medications that are used to treat bacterial infections. They are widely available in various forms, such as pills, capsules, injections, creams, and ointments. They either kill bacteria or inhibit their growth to effectively eliminate infections. They target specific mechanisms or structures within bacterial cells and interfering with their vital functions and preventing their reproduction. Besides this, they assist in enhancing the immune system of individuals. As a result, antibiotics are utilized to treat various diseases, such as urinary tract infections (UTI), respiratory tract infections, skin infections, and certain sexually transmitted diseases among individuals.
At present, the increasing prevalence of numerous chronic diseases among the masses around the world is contributing to the growth of the market. Additionally, the wide availability of antibiotics through online and offline stores across the globe is strengthening the growth of the market. Apart from this, the growing demand for topical antibiotics, as they minimize the risk of surgical site infections among individuals, is positively influencing the market. Moreover, the increasing employment of antibiotics in livestock farming to safeguard animal health and welfare and support food safety is bolstering the growth of the market. In line with this, the rising demand for antibiotics among the geriatric population is supporting the growth of the market. Furthermore, the increasing consumer awareness about preventive healthcare measures is impelling the growth of the market.
Rising prevalence of infectious diseases
There is a rise in the prevalence of infectious diseases, such as pneumonia, tuberculosis, urinary tract infections (UTI), gastrointestinal infections, and sepsis, among the masses across the globe. People are increasingly suffering from these diseases due to inadequate sanitation, which contributes to the spread of bacterial infections. In addition, the emergence of drug-resistant bacteria is increasing the demand for antibiotics. There is a rise in the demand for effective antibiotics that assist in treating these infections. Antibiotics are specifically designed to target and eliminate bacterial infections. They effectively kill bacteria in the body and promote healing among individuals. Furthermore, antibiotics are used under the guidance of healthcare professionals to optimize patient outcomes.
Increasing occurrence of antimicrobial resistance (AMR)
There is a rise in the occurrence of antimicrobial resistance (AMR) across the globe, which is driving the antibiotics market. AMR occurs when bacteria, viruses, parasites, or fungi evolve and become resistant to the drugs used to treat them. It reduces the effectiveness of antibiotics and causes longer and more severe infections, increased healthcare costs, and high mortality rates among individuals. Overuse and misuse of antibiotics are contributing to the development of drug-resistant bacteria, which makes traditional antibiotics less effective. In addition, multidrug-resistant strains, such as Methicillin-resistant Staphylococcus aureus (MRSA) and Carbapenem-resistant Enterobacteriaceae (CRE), are more prevalent. This necessitates the development of new antibiotics or alternative treatments to combat these resistant strains.
Technological advancements in antibiotics
Innovations in biotechnology, molecular biology, and drug discovery techniques assist in improving the efficiency and effectiveness of antibiotic development. Genomics and high-throughput screening allow the identification of potential drug targets and the screening of large compound libraries. Moreover, computer-aided drug design enables the prediction of drug efficacy and optimizes antibiotic candidates. These technological advancements streamline the antibiotic discovery process and reduce the time and costs associated with traditional methods. Additionally, advancements in diagnostic techniques, such as rapid pathogen identification and susceptibility testing, assist in appropriate antibiotic selection and prescribing that provides enhanced patient outcomes. Furthermore, technological advancements aid in the development of new and more potent antibiotics to address infectious diseases and antimicrobial resistance.
IMARC Group provides an analysis of the key trends in each segment of the global antibiotics market report, along with forecasts at the global, regional and country levels from 2024-2032. Our report has categorized the market based on action mechanism, drug class, spectrum of activity, route of administration and end user.
Cell Wall Synthesis Inhibitors
Protein Synthesis Inhibitors
DNA Synthesis Inhibitors
RNA Synthesis Inhibitors
Mycolic Acid Inhibitors
Others
Cell wall synthesis inhibitors represent the largest market segment
The report has provided a detailed breakup and analysis of the market based on the action mechanism. This includes cell wall synthesis inhibitors, protein synthesis inhibitors, DNA synthesis inhibitors, RNA synthesis inhibitors, mycolic acid inhibitors, and others. According to the report, cell wall synthesis represented the largest segment.
Cell wall synthesis is a class of antibiotics that target the bacterial cell wall. These antibiotics interfere with the process of cell wall synthesis, which causes cell wall damage and eventual bacterial death. In addition, penicillin, cephalosporins, and carbapenems are some of the cell wall synthesis inhibitors. They work by inhibiting enzymes called penicillin-binding proteins (PBPs) that are involved in the cross-linking of peptidoglycan chains. Moreover, cell wall synthesis inhibitors are particularly effective against gram-positive bacteria due to their thicker peptidoglycan layer, which provides a greater target for disruption.
Cephalosporin
Penicillin
Fluoroquinolone
Macrolide
Carbapenem
Aminoglycoside
Others
Penicillin accounts for the majority of the market share
The report has provided a detailed breakup and analysis of the market based on the drug class. This includes cephalosporin, penicillin, fluoroquinolone, macrolide, carbapenem, aminoglycoside, and others. According to the report, penicillin represented the largest segment.
Penicillin is a widely used class of antibiotics that belongs to the beta-lactam drug class. It works by inhibiting the synthesis of bacterial cell walls that causes cell wall damage and bacterial death. It is considered an essential medicine and is widely available as generic drugs. Apart from this, it is widely used in various healthcare settings, such as hospitals, clinics, and outpatient settings. In addition, the rising utilization of penicillin, as it is effective against various bacterial infections, is contributing to the growth of the market.
Broad-Spectrum Antibiotics
Narrow-Spectrum Antibiotics
Broad-spectrum antibiotics hold the biggest market share
The report has provided a detailed breakup and analysis of the market based on the spectrum of activity. This includes broad-spectrum antibiotics and narrow-spectrum antibiotics. According to the report, broad-spectrum antibiotics represented the largest segment.
Broad-spectrum antibiotics are a class of antibiotics that exhibit activity against a wide range of bacteria, such as gram-positive and gram-negative bacteria. In line with this, the rising adoption of broader spectrum antibiotics, as they are effective against a broader range of microorganisms compared to narrow-spectrum antibiotics, is bolstering the growth of the market. Apart from this, broad-spectrum antibiotics assist in treating infections when the causative bacteria are unknown or when the infection involves multiple bacterial species. The appropriate use of broad-spectrum antibiotics minimizes the risks of infections in the body.
Oral
Parenteral
Topical
Others
Parenteral dominates the market segment
The report has provided a detailed breakup and analysis of the market based on the route of administration. This includes oral, parenteral, topical, and others. According to the report, parenteral represented the largest segment.
Parenteral antibiotics are administered via routes other than the digestive tract, such as intravenous (IV), intramuscular (IM), or subcutaneous (SC) routes. These routes allow for direct delivery of the medication into the bloodstream or deep tissues, bypassing the gastrointestinal system. In addition, parenteral antibiotics provide rapid and predictable drug absorption and immediate therapeutic effect. They are also suitable for patients with compromised gastrointestinal function. Apart from this, it allows for accurate dosing and is particularly beneficial in cases where high drug concentrations are needed or when oral administration is not possible.
Hospitals
Specialty Clinics
Others
Hospitals accounted for the largest market share
The report has provided a detailed breakup and analysis of the market based on the end user. This includes hospitals, specialty clinics, and others. According to the report, hospitals represented the largest segment.
Antibiotics are widely consumed in hospitals due to the increased number of patients staying in this healthcare setting. Antibiotics are administered to patients admitted with severe infections. They are also administered before surgical procedures to reduce the risk of bacterial contamination. In line with this, the rising utilization of antibiotics among individual post-surgical prophylaxis is contributing to the growth of the market. Apart from this, the increasing consumption of antibiotics due to the rising risk of multidrug-resistant infections in hospitals is supporting the growth of the market.
North America
United States
Canada
Asia-Pacific
China
Japan
India
South Korea
Australia
Indonesia
Others
Europe
Germany
France
United Kingdom
Italy
Spain
Russia
Others
Latin America
Brazil
Mexico
Others
Middle East and Africa
Asia Pacific exhibits a clear dominance, accounting for the largest antibiotics market share
The report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, Asia Pacific represented the largest market.
Asia Pacific held the biggest market share due to the improved healthcare infrastructure. In line with this, the growing prevalence of bacterial infections to poor sanitation is contributing to the growth of the market in the Asia Pacific region. Apart from this, the increasing demand for advanced antibiotics that can effectively combat multidrug-resistant bacteria is supporting the growth of the market. Furthermore, the presence of a large number of generic drug manufacturers is propelling the growth of the market in the region.
Key players in the industry are investing in research and development (R&D) activities to discover and develop new antibiotics and focusing on antibiotic resistance, expanding the spectrum of activity, and improving the efficacy and safety profiles of antibiotics. Apart from this, they are engaging in collaboration with research institutions, academic organizations, and government bodies to leverage their expertise and address the challenges associated with antibiotic development, such as high costs and regulatory compliances. Moreover, antibiotic companies are actively promoting antibiotic stewardship programs that encourage responsible and appropriate use of antibiotics to avoid overdosage and misusage. Furthermore, companies are increasingly conducting clinical trials and adhering to safety and efficacy standards to obtain regulatory approvals for their antibiotics.
Allergan Plc (AbbVie Inc.)
Basilea Pharmaceutica AG
GlaxoSmithKline Plc
Johnson & Johnson
Melinta Therapeutics
Merck & Co. Inc.
Nabriva Therapeutics Plc
Paratek Pharmaceuticals Inc.
Pfizer Inc.
Sanofi SA
Spero Therapeutics
Tetraphase Pharmaceuticals
In 2021, Sandoz, a Novartis division, successfully completed the acquisition of GlaxoSmithKline's (GSK) cephalosporin antibiotics business. This acquisition provides them rights to three established brands (Zinnat, Zinacef and Fortum) in more than 100 markets to Sandoz.
In January 2020, Merck & Co. Inc. announced that U.S. Food and Drug Administration (FDA) has approved a New Drug Application (NDA) for DIFICID(R) (fidaxomicin) for oral suspension, and a supplemental New Drug Application (sNDA) for DIFICID tablets for the treatment of Clostridioides (formerly Clostridium) difficile-associated diarrhea (CDAD) in children aged six months and older.