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市场调查报告书
商品编码
1540838
2024-2032 年预装色谱管柱市场报告(按类型、技术、应用、最终用途和地区)Prepacked Chromatography Columns Market Report by Type, Technique, Application, End-Use, and Region 2024-2032 |
2023年,IMARC Group预载层析柱市场规模达20亿美元。各种慢性病的盛行率不断上升、用于疾病管理的生物製药的需求不断增长以及各行业色谱法的使用不断增加是推动市场成长的一些主要因素。
主要市场驱动力:对需要高纯度分离技术的生物製药和单株药物的需求不断增长,是市场的主要驱动力。色谱技术的进步提高了效率并缩短了处理时间,使预装柱更具吸引力。药品和生物技术领域严格品质控制的监管压力进一步推动了市场的发展。
主要市场趋势:越来越多地采用一次性技术,最大限度地减少交叉污染并提高效率,这是市场的主要趋势。由于对更高吞吐量和责任的需求,也出现了向自动化和流程集约化的转变。先进材料和改进的色谱柱设计的整合以增强分离性能是另一个值得注意的趋势。
地区趋势:北美是预装色谱管市场成长最大的地区。强劲的生物製药行业、对研发 (R&D) 的重大新投资以及对液滴纯度和品质的严格监管要求正在推动整个北美地区的市场成长。该地区先进的医疗保健基础设施和领先製药公司的存在进一步推动了市场的成长。
竞争格局:预装色谱管行业的一些主要市场参与者包括 Agilent Technologies Inc.、Bio-RAD Laboratories Inc.、Knauer Wissenschaftliche Gerate GmbH、Merck & Co. Inc.、Pall Corporation (Danaher Corporation)、Repligen Corporation、岛津公司、赛默飞世尔科技公司、东曹公司、沃特世公司等。
挑战与机会:市场面临各种挑战,包括与先进色谱系统相关的高成本以及大规模製造流程的可扩展性有限。然而,市场也面临一些机会,例如对生物製药和个人化医疗不断增长的需求,这推动了色谱技术的创新。
生物製药需求增加
癌症、糖尿病、心血管疾病和自体免疫疾病等各种慢性疾病的盛行率不断上升,正在推动市场的成长。再加上疾病管理生物製药的需求不断增长,正在加强市场的成长。根据 NIH 统计,2022 年印度癌症发病病例数估计为 14,61,427 例(粗率:每 10 万人中 100.4 例)。在儿童(0-14岁)癌症中,淋巴球白血病(男孩:29.2%,女孩:24.2%)是主要部位。与2020 年相比,2025 年癌症病例的发生率预计将增加12.8% 例如,IDF 糖尿病地图集(2021 年)报告称,10.5% 的成年人口(20-79 岁)患有糖尿病,而几乎一半人不知道这一点他们正在忍受这种状况。 IDF 预测显示,到 2045 年,大约 7.83 亿成年人中,八分之一的人患有糖尿病,这一数字将增加 46%。这极大地影响了预装色谱柱的市场统计。
色谱技术的重大进步
色谱技术的不断进步也推动了市场的发展。例如,包括高效液相层析 (HPLC) 和亲和色谱在内的色谱技术不断创新,正在提高分离的效率、速度和分辨率。色谱在环境测试中的广泛采用正在影响市场的成长。例如,2023 年 6 月,安捷伦科技公司宣布推出两款新型液相层析质谱系统 (LCMS):Agilent 6495D LC/TQ 和 Agilent Revident LC/Q-TQF。为了促进 Revident LC/Q-TQF 的高端效能,安捷伦也推出了新的 Agilent MassHunter Explorer 分析软体和新的 Agilent ChemVistra 谱库管理软体。预计这将推动未来几年预装色谱柱市场的预测。
对生物加工和一次性技术的日益重视
生物製药和生物技术产业越来越关註一次性技术,以简化生产并减少交叉污染风险,这有助于市场的成长。一次性预装色谱柱无需进行批次之间的清洁和验证步骤,从而优化了宝贵的生产时间,从而实现更高效、更具成本效益的生产。例如,2023 年 9 月,专注于生物加工技术领先地位的生命科学公司 Repligen Corporation 宣布已签订最终协议,收购瑞典莫恩达尔的私人公司 Metenova AB (Metenova)。 Metenova 预计在 2023 财年实现收入 2,400 万至 2,500 万美元,其磁力混合和传动系统技术取得成功,这些技术被全球生物製药公司和合约开发和製造组织 (CDMO) 广泛使用。该公司最近凭藉其现有不銹钢(重复使用)产品线的成功,推出了 MixOne 平台,进入了一次性混合市场。
IMARC Group提供了每个细分市场的主要趋势分析,以及 2024-2032 年全球、区域和国家层面的预测。我们的报告根据类型、技术、应用和最终用途对市场进行了分类。
<100毫升
100-1000毫升
>1000毫升
>1000ML占大部分市场份额
该报告根据类型提供了详细的市场细分和分析。这包括 <100 ML、100-1000 ML 和 >1000 ML。报告称,>1000 ML 代表了最大的细分市场。
不同行业垂直领域对大尺寸色谱柱的日益青睐正在推动细分市场的发展。 >1000 ML 预装管柱通常用于纯化生物分子,例如单株抗体、蛋白质和疫苗。它们有助于高容量色谱分离,确保生产纯净、高品质的生物製药产品。此外,食品和饮料 (F&B) 製造商利用超过 1000 mL 的预装管柱来执行风味萃取、品质控制以及糖、胺基酸和着色剂等成分分离等任务。这些色谱柱有助于实现一致的产品品质并符合食品安全法规。在化学研究和开发 (R&D) 中,这些色谱柱对于合成和纯化化合物至关重要。研究人员可以有效地扩大其色谱工艺,节省时间和资源,同时确保产品纯度。
疏水固定相层析
离子交换色谱法
多模式色谱法
其他的
离子交换色谱占大部分市场份额
报告还提供了基于该技术的详细市场细分和分析。这包括疏水固定相层析、离子交换层析、多模式层析等。报告称,离子交换层析法占据最大的市场份额。
离子交换层析用途广泛,可应用于多种生物分子,包括蛋白质、核酸和其他带电分子。这种适应性使其适用于各种研究和工业应用。此外,它还根据被分离分子的电荷提供出色的选择性。透过使用具有不同官能基的离子交换树脂,研究人员可以有效地从复杂混合物中分离和纯化目标分子。除此之外,它还提供高分辨率分离,能够分离具有不同电荷特性的密切相关的物质。此外,它可以轻鬆扩大规模用于工业生产,使其适用于生物製药、食品加工和其他行业的大规模纯化过程。
树脂筛选
蛋白质纯化
样品製备
阴阳离子交换
其他的
样品製备代表最大的细分市场
该报告根据应用程式提供了详细的市场细分和分析。这包括树脂筛选、蛋白质纯化、样品製备、阴离子和阳离子交换等。报告称,样品製备占据最大的市场份额。
样品製备是色谱分析的基本先决条件,推动了该市场的成长。它涉及从复杂样品中提取、净化和浓缩目标分子,确保只有相关化合物到达色谱柱。样品製备的品质直接影响后续色谱分析的准确性和灵敏度,是不可或缺的步骤。此外,包括製药、生物技术、食品和饮料、环境监测和医疗保健在内的多种行业都严重依赖色谱法进行品质控制、研究和产品开发。此外,高效液相层析 (HPLC) 和质谱 (MS) 等分析技术的不断进步,需要能够满足不断变化的需求的样品製备方法。
製药和生物技术公司
研究实验室
水与环境
食品和饮料
其他的
製药和生物技术公司占据最大的市场份额
报告还提供了基于最终用途的详细市场细分和分析。这包括製药和生物技术公司、研究实验室、水和环境、食品和饮料等。报告称,製药和生物技术公司代表了最大的市场领域。
製药和生物技术公司必须遵守严格的监管要求,以确保其产品的安全性和有效性,这进一步推动了该市场的成长。色谱法是一种值得信赖的标准化方法,用于表征和纯化化合物,使预装柱成为实现合规性和保持製造一致性的有吸引力的选择。此外,包括单株抗体和基因疗法在内的生物製药领域的不断进步,导致对针对这些复杂分子量身定制的专用色谱柱的需求不断增加。此外,这些产业在药物开发、生产和品质控制的各个阶段依赖蛋白质、抗体和核酸等生物分子的精确、高效的分离和纯化。预装层析管提供即用型解决方案,可大幅简化这些流程,减少时间和劳动成本。
北美洲
美国
加拿大
亚太地区
中国
日本
印度
韩国
澳洲
印尼
其他的
欧洲
德国
法国
英国
义大利
西班牙
俄罗斯
其他的
拉丁美洲
巴西
墨西哥
其他的
中东和非洲
北美市场领先,占据最大的预载色谱柱市场份额
该报告还对所有主要区域市场进行了全面分析,其中包括北美(美国和加拿大);欧洲(德国、法国、英国、义大利、西班牙、俄罗斯等);亚太地区(中国、日本、印度、韩国、澳洲、印尼等);拉丁美洲(巴西、墨西哥等);以及中东和非洲。报告称,北美是预装色谱柱最大的区域市场。
北美是许多从事药物发现、开发和生产的製药和生物技术公司的所在地,这推动了市场的成长。此外,北美的製药和生物技术产业受到美国食品药物管理局 (FDA) 和加拿大卫生部製定的严格监管标准。除此之外,色谱柱製造业的几个主要参与者的总部或在北美拥有重要的业务。主要行业参与者的集中促进了竞争、创新和广泛的产品供应。此外,该地区拥有先进的医疗基础设施,包括尖端的诊断实验室和医疗设施。色谱法广泛应用于临床诊断和研究,进一步推动了对预装柱的需求。例如,2024年2月,岛津製作所从Activated Research Company, LLC(美国明尼苏达州ARC)收购了气相层析仪(GC)催化微反应业务。
市场研究报告也对市场竞争格局进行了全面分析。也提供了所有主要公司的详细资料。预装色谱柱产业的一些主要市场参与者包括 Agilent Technologies Inc.、Bio-RAD Laboratories Inc.、Knauer Wissenschaftliche Gerate GmbH、Merck & Co. Inc.、Pall Corporation (Danaher Corporation)、Repligen Corporation、Shimadzu Corporation、赛默飞世尔科技公司、东曹公司、沃特世公司。
(请注意,这只是关键参与者的部分列表,报告中提供了完整列表。)
预装层析市场的竞争格局以 GE Healthcare、Merck KGaA、Bio-Rad Laboratories 和 Thermo Fisher Scientific 等主要参与者的存在为特征。这些公司专注于持续创新、併购和策略合作伙伴关係,以增强其市场地位。例如,2022 年 6 月,Bio-Rad Laboratories, Inc. 宣布推出 EconoFit 低压预载层析管柱包,以支援蛋白质纯化工作流程开发中的树脂筛选实验。
2023 年 8 月,Water Corporation 推出了第一款新的尺寸排阻色谱柱,旨在改进分析,同时降低基因治疗的成本,尤其是腺相关病毒 (AAV) 载体的成本。新型 Waters XBridge Premier GTx BEH SEC 色谱柱使 AAV 效力和安全性的测量速度提高了一倍。
2024 年 5 月,岛津公司宣布发布 Peakintelligence for LC,该软体结合了专有的液相层析 (LC) 和使用 AI 技术开发的演算法。该演算法是使用 Ajinomoto Co, inc. 的 LC资料基于人工智慧学习而开发的。
2024 年 2 月,Thermo Fisher Scientific 推出了 Dionex Inuvian 离子层析 (IC) 系统,用于离子层析分析。这项新技术的设计可重新配置,可供食品和饮料、市政供水等多个行业的科学家使用。该技术还可以识别石油和天然气中的腐蚀性污染物,同时为食品、饮料和药品中的离子化合物提供品质保证和品质控制。
The global prepacked chromatography columns market size reached US$ 2.0 Billion in 2023. Looking forward, IMARC Group expects the market to reach US$ 3.7 Billion by 2032, exhibiting a growth rate (CAGR) of 6.6% during 2024-2032. The growing prevalence of various chronic diseases, the rising demand for biopharmaceuticals for disease management, and increasing utilization of chromatography across various industries are some of the major factors propelling the growth of the market.
Major Market Drivers: The rising demand for biopharmaceuticals and monoclonal, which require high-purity separation techniques represents a major driver of the market. Advancements in chromatography technology are leading to increased efficiency and reduced process times, making prepacked columns more attractive. Regulatory pressures for stringent quality control in pharmaceuticals and biotechnology further propel the market.
Key Market Trends: The increasing adoption of single-use technologies, which minimize cross-contamination and enhance efficiency represent the key trends in the market. There is also a shift towards automation and process intensification, driven by the need for higher throughput and responsibility. The integration of advanced materials and improved column designs for enhanced separation performance is another notable trend.
Geographical Trends: North America accounted for the largest region in the prepacked chromatography columns market growth. The robust biopharmaceutical industry, significant new investments in research and development (R&D), and strict regulatory requirements for drop purity and quality are driving the market growth across the North American region. The region's advanced healthcare infrastructure and the presence of leading pharmaceutical companies further fuel the market growth.
Competitive Landscape: Some of the major market players in the prepacked chromatography columns industry include Agilent Technologies Inc., Bio-RAD Laboratories Inc., Knauer Wissenschaftliche Gerate GmbH, Merck & Co. Inc., Pall Corporation (Danaher Corporation), Repligen Corporation, Shimadzu Corporation, Thermo Fisher Scientific Inc., Tosoh Corporation, Waters Corporation, among many others.
Challenges and Opportunities: The market faces various challenges including high costs associated with advanced chromatography systems and limited scalability for large-scale manufacturing processes. However, the market also faces several opportunities such as the growing demand for biopharmaceuticals and personalized medicine, which drives innovations in chromatography techniques.
Increased Demand for Biopharmaceuticals
The rising prevalence of various chronic diseases including cancer, diabetes, cardiovascular disorders, and autoimmune conditions is driving the growth of the market. This, coupled with the escalating demand for biopharmaceuticals for disease management is strengthening the growth of the market. According to NIH, the estimated number of incident cases of cancer in India for the year 2022 was found to be 14,61,427 (crude rate:100.4 per 100000). Among the childhood (0-14 yr) cancers, lymphoid leukemia (boys: 29.2% and girls: 24.2%) was the leading site. The incidence of cancer cases is estimated to increase by 12.8% in 2025 as compared to 2020. For instance, IDF Diabetes Atlas (2021) reports that 10.5% of the adult population (20-79 years) has diabetes, with almost half unaware that they are living with the condition. By 2045, IDF projections show that one in eight adults approximately 783 million, will be living with diabetes an increase of 46%. This is infleuncing the prepacked chromatography columns market statistics significantly.
Significant Technological Advancement in Chromatography
The market is also driven by continuous advancements in chromatography technology. For instance, ongoing innovations in chromatographic techniques including high-performance liquid chromatography (HPLC) and affinity chromatography are improving the efficiency, speed, and resolution of separation. The widespread adoption of chromatography in environmental testing is influencing the growth of the market. For instance, in June 2023, Agilent Technologies Inc. announced two new liquid chromatography-mass spectrometry systems (LCMS), the Agilent 6495D LC/TQ and the Agilent Revident LC/Q-TQF. Facilitating the high-end performance of the Revident LC/Q-TQF, Agilent is also announcing the new Agilent MassHunter Explorer Profiling software and the new Agilent ChemVistra library manager software. This is expected to fuel the prepacked chromatography columns market forecast over the coming years.
Rising Emphasis on Bioprocessing and Single-Use Technologies
The increasing focus of biopharmaceutical and biotechnology industries towards single-use technologies to streamline production and reduce cross-contamination risk is contributing to the growth of the market. Single-use prepackaged columns optimize the use of valuable production time by eliminating the need for cleaning and validation steps between batches which leads to more efficient and cost-effective manufacturing. For instance, in September 2023, Repligen Corporation, a life sciences company focused on bioprocessing technology leadership, announced that it has entered into a definitive agreement to acquire privately held Metenova AB (Metenova) of Molndal, Sweden. Metenova is projected to generate revenues of $24 million to $25 million for fiscal year 2023, led by the success of its magnetic mixing and drive train technologies that are widely used by global biopharmaceutical companies and contract development and manufacturing organizations (CDMOs). The company recently entered the single-use mixing market with the launch of its MixOne platform, leveraging the success of its existing stainless steel (repeat-use) product line.
IMARC Group provides an analysis of the key trends in each segment of the market, along with forecasts at the global, regional, and country levels for 2024-2032. Our report has categorized the market based on type, technique, application, and end-use.
<100 ML
100-1000 ML
>1000 ML
>1000 ML accounts for the majority of the market share
The report has provided a detailed breakup and analysis of the market based on the type. This includes <100 ML, 100-1000 ML, and >1000 ML. According to the report, >1000 ML represented the largest market segment.
The rising preference for large column sizes across different industry verticals is driving the market segment. >1000 ML prepacked columns are commonly employed for the purification of biomolecules such as monoclonal antibodies, proteins, and vaccines. They facilitate high-capacity chromatographic separations, ensuring the production of pure and high-quality biopharmaceutical products. Additionally, food and beverage (F&B) manufacturers utilize >1000 mL prepacked columns for tasks like flavor extraction, quality control, and the separation of components like sugars, amino acids, and colorants. These columns aid in achieving consistent product quality and compliance with food safety regulations. In chemical research and development (R&D), these columns are essential for synthesizing and purifying compounds. Researchers can scale up their chromatographic processes efficiently, saving time and resources while ensuring product purity.
Hydrophobic Stationary Phase Chromatography
Ion-Exchange Chromatography
Multimodal Chromatography
Others
Ion-exchange chromatography holds the majority of the market share
A detailed breakup and analysis of the market based on the technique has also been provided in the report. This includes hydrophobic stationary phase chromatography, ion-exchange chromatography, multimodal chromatography, and others. According to the report, ion-exchange chromatography accounts for the largest market share.
Ion-exchange chromatography is versatile and can be applied to a wide range of biomolecules, including proteins, nucleic acids, and other charged molecules. This adaptability makes it suitable for various research and industrial applications. Additionally, it offers excellent selectivity based on the charge of the molecules being separated. By using ion-exchange resins with different functional groups, researchers can effectively separate and purify target molecules from complex mixtures. Apart from this, it provides high-resolution separation, enabling the isolation of closely related species with different charge properties. Furthermore, it can be easily scaled up for industrial production, making it suitable for large-scale purification processes in biopharmaceuticals, food processing, and other industries.
Resin Screening
Protein Purification
Sample Preparation
Anion and Cation Exchange
Others
Sample preparation represents the largest market segment
The report has provided a detailed breakup and analysis of the market based on the application. This includes resin screening, protein purification, sample preparation, anion and cation exchange, and others. According to the report, sample preparation holds the largest market share.
Sample preparation is a fundamental prerequisite for chromatographic analyses which is fueling the segment growth in the market. It involves the extraction, clean-up, and concentration of target molecules from complex samples, ensuring that only relevant compounds reach the chromatography columns. The quality of sample preparation directly influences the accuracy and sensitivity of subsequent chromatographic analyses, making it an essential step. Additionally, diverse industries, including pharmaceuticals, biotechnology, food and beverage, environmental monitoring, and healthcare, heavily rely on chromatography for quality control, research, and product development. Furthermore, ongoing advancements in analytical techniques, such as high-performance liquid chromatography (HPLC) and mass spectrometry (MS), demand sample preparation methods that can cater to evolving needs.
Pharmaceutical and Biotechnology Companies
Research Laboratories
Water and Environmental
Food and Beverages
Others
Pharmaceutical and biotechnology companies account for the largest market share
A detailed breakup and analysis of the market based on the end-use has also been provided in the report. This includes pharmaceutical and biotechnology companies, research laboratories, water and environmental, food and beverages, and others. According to the report, pharmaceutical and biotechnology companies represent the largest market segment.
Pharmaceutical and biotechnology companies are subject to rigorous regulatory requirements to ensure the safety and efficacy of their products which is further driving the segment growth in the market. Chromatography is a trusted and standardized method for characterizing and purifying compounds, making prepacked columns an attractive option for achieving compliance and maintaining consistency in manufacturing. Moreover, the continuous advancements in biopharmaceuticals, including monoclonal antibodies and gene therapies, have led to increased demand for specialized chromatography columns tailored to these complex molecules. Furthermore, these industries rely on precise and efficient separation and purification of biomolecules, such as proteins, antibodies, and nucleic acids, at various stages of drug development, production, and quality control. Prepacked chromatography columns offer ready-to-use solutions that significantly streamline these processes, reducing time and labor costs.
North America
United States
Canada
Asia Pacific
China
Japan
India
South Korea
Australia
Indonesia
Others
Europe
Germany
France
United Kingdom
Italy
Spain
Russia
Others
Latin America
Brazil
Mexico
Others
Middle East and Africa
North America leads the market, accounting for the largest prepacked chromatography columns market share
The report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, North America represents the largest regional market for prepacked chromatography columns.
North America is home to numerous pharmaceutical and biotechnology companies engaged in drug discovery, development, and production which is driving the market growth. Additionally, pharmaceutical and biotechnology sectors in North America are subject to strict regulatory standards set by the U.S. Food and Drug Administration (FDA) and Health Canada. Apart from this, several major players in the chromatography column manufacturing industry are headquartered or have a significant presence in North America. This concentration of key industry players fosters competition, innovation, and a wide range of product offerings. Furthermore, the region boasts advanced healthcare infrastructure, including cutting-edge diagnostic laboratories and healthcare facilities. Chromatography is extensively used in clinical diagnostics and research, further fueling the demand for prepacked columns. For instance, in February 2024, Shimadzu Corporation acquired the catalytic micro-reactive business for gas chromatography (GC) from Activated Research Company, LLC (ARC, Minnesota, USA).
The market research report has also provided a comprehensive analysis of the competitive landscape in the market. Detailed profiles of all major companies have also been provided. Some of the major market players in the prepacked chromatography columns industry include Agilent Technologies Inc., Bio-RAD Laboratories Inc., Knauer Wissenschaftliche Gerate GmbH, Merck & Co. Inc., Pall Corporation (Danaher Corporation), Repligen Corporation, Shimadzu Corporation, Thermo Fisher Scientific Inc., Tosoh Corporation, Waters Corporation.
(Please note that this is only a partial list of the key players, and the complete list is provided in the report.)
The competitive landscape of the prepacked chromatography market is featured by the presence of major players including GE Healthcare, Merck KGaA, Bio-Rad Laboratories, and Thermo Fisher Scientific. These companies focus on continuous innovation, mergers and acquisitions, and strategic partnerships to enhance their market position. For instance, in June 2022, Bio-Rad Laboratories, Inc. announced the launch of EconoFit Low-Pressure prepacked Chromatography Column Packs to support resin screening experiments in the development of protein purification workflows.
In August 2023, Water Corporation introduced the first in a new line of size exclusion chromatography columns the game at improving the analysis while lowering the cost of gene therapy, especially adeno associated viral (AAV) vectors. The new Waters XBridge Premier GTx BEH SEC columns doubles the speed of measuring the potency and safety of AAVs.
In May 2024, Shimadzu Corporation announced the release of Peakintelligence for LC, software incorporating a proprietary liquid chromatography (LC) with algorithms developed using AI technology. The algorithm was developed based on AI learning using LC data from Ajinomoto Co, inc.
In February 2024, Thermo Fisher Scientific launched the Dionex Inuvian Ion Chromatography (IC) system, for ion chromatography analysis. Designed to be reconfigurable, the new technology can be used by scientists working in a variety of industries including food and beverage, municipal water, and more. This technology can also identify corrosive contaminants in oil and gas while providing quality assurance and quality control of ionic compounds in food, beverages, and pharmaceuticals.