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2024-2032 年蛋白质治疗市场报告(按产品(单株抗体、人类胰岛素、促红血球生成素、凝血因子、融合蛋白等)、治疗领域、功能和地区)Protein Therapeutics Market Report by Product (Monoclonal Antibodies, Human Insulin, Erythropoietin, Clotting Factors, Fusion Protein, and Others), Therapy Area, Function, and Region 2024-2032 |
2023年全球蛋白质治疗市场规模达3,456亿IMARC Group。癌症、糖尿病、心血管疾病和自体免疫疾病等慢性疾病的盛行率不断上升,蛋白质工程技术的快速进步,生物製药行业的不断扩大以及产品在不同治疗领域的广泛应用是推动市场发展的一些因素。
蛋白质疗法是一类利用蛋白质或胜肽来预防、控製或治癒疾病的医学治疗方法。这些疗法旨在针对体内的特定分子或途径,提供高度针对性的治疗方法。他们为多种疾病提供创新的解决方案,包括癌症、自体免疫疾病、遗传性疾病等。它们可以来自天然来源,也可以透过重组 DNA 技术生产,从而可以开发高度特异性和有效的疗法。这些治疗性蛋白质可以采取多种形式,包括单株抗体、生长因子、酵素和细胞激素。它们与体内的特定受体或分子相互作用,调节细胞过程,抑製或刺激免疫反应,或直接针对致病因子。蛋白质疗法的优点在于其高特异性、效力和低毒性。与传统的小分子药物相比,它们通常具有更高的疗效和更少的副作用。他们大大推进了医学领域的发展,提供了新颖的治疗选择并改善了各种疾病的患者治疗结果。
全球市场的主要驱动力是对个人化医疗的日益关注。与此一致的是,不断增加的研发活动和不断扩大的医疗基础设施正在为市场做出巨大贡献。此外,製造流程的进步预计将推动市场的发展。除此之外,基因工程、蛋白质合成和生产技术的突破提高了蛋白质治疗的效率和有效性,对市场产生了积极影响。此外,癌症、糖尿病、心血管疾病和自体免疫疾病等慢性疾病的日益普及正在催化市场。此外,蛋白质疗法在肿瘤学中的广泛应用正在刺激市场。此外,药物输送系统的快速创新改善了蛋白质治疗药物的输送,提高了其疗效和患者依从性。缓释製剂、奈米颗粒和标靶药物递送系统等新型递送方法可透过增加蛋白质药物的治疗潜力来推动市场成长。
不断增加的生物製药研发投资
由于蛋白质药物具有高特异性、有效性和标靶性,生物製药公司和研究机构越来越关注其开发。生物製药领域研发投资的增加正在推动蛋白质疗法的进步。这些投资支持与蛋白质工程、药物发现和配方优化相关的研究活动,从而开发新型和改进的蛋白质疗法。此外,分配给研发的大量资金使研究人员能够探索新的治疗靶点,优化蛋白质结构以增强活性,并进行广泛的临床前和临床试验。这些努力透过引入针对各种疾病的创新疗法,有助于扩大市场。此外,不断增长的研发投资有助于扩大蛋白质疗法的生产工艺,使其更容易获得且更具成本效益。这使得蛋白质药物的商业化和市场渗透率得到提高。
生物相似药的扩展
生物相似药市场的扩张对市场做出了重大贡献。生物相似药是与已核准的参考蛋白治疗药物高度相似的生物药物。随着几种重磅生物製剂的专利到期,生物相似药市场正在迅速扩大。生物相似药的出现为昂贵的蛋白质疗法提供了具有成本效益的替代品,使患者和医疗保健系统更容易获得它们。负担能力的提高使患者能够获得必要的治疗,从而推动市场成长。此外,生物相似药的引入促进了市场竞争。竞争导致价格下降,鼓励市场扩张,并为生物相似药製造商和参考蛋白治疗公司创造创新和改进产品的机会。此外,生物相似药的监管框架和指南已经更加完善和简化,为其开发和批准提供了明确的途径。这给医疗保健界注入了信心,并导致生物相似药的采用增加。随着生物相似药市场的扩大,它刺激了蛋白质疗法的进一步研究和开发工作。製造商努力开发更先进和差异化的生物相似药,为市场创造了积极的前景。
人口老化加剧
人口老化的加剧对市场有正面影响。随着全球人口老化,阿兹海默症、帕金森氏症、黄斑部病变和骨质疏鬆症等与年龄相关的疾病和病症的盛行率更高。正在开发和利用蛋白质疗法来解决老龄化人口面临的这些特定健康挑战。此外,蛋白质疗法为与年龄相关的疾病提供了有针对性的治疗选择,与传统疗法相比,可以提高疗效并减少副作用。它们可以针对特定的分子途径并解决这些疾病的潜在机制,从而改善患者的治疗结果和生活品质。此外,老龄化人口不断增长的产品需求正在推动市场成长。製药公司和研究机构正在投资开发新型蛋白质疗法,以满足这一人群的特定需求。此外,日益增长的老龄化人口为蛋白质治疗创造了更大的市场,促使製造商扩大产品组合併增加产量。这反过来又导致蛋白质疗法的更广泛应用并进一步推动市场成长。
The global protein therapeutics market size reached US$ 345.6 Billion in 2023. Looking forward, IMARC Group expects the market to reach US$ 603.5 Billion by 2032, exhibiting a growth rate (CAGR) of 6.2% during 2024-2032. The increasing prevalence of chronic diseases such as cancer, diabetes, cardiovascular diseases, and autoimmune disorders, the rapid technological advancements in protein engineering, the expanding biopharmaceutical industry, and the widespread product applications in diverse therapeutic areas are some factors propelling the market.
Protein therapeutics is a class of medical treatments utilizing proteins or peptides to prevent, manage, or cure diseases. These therapeutics are designed to target specific molecules or pathways within the body, providing a highly targeted approach to treatment. They offer innovative solutions for a wide range of conditions, including cancer, autoimmune disorders, genetic diseases, and more. They can be derived from natural sources or produced through recombinant DNA technology, allowing for the development of highly specific and potent therapies. These therapeutic proteins can take various forms, including monoclonal antibodies, growth factors, enzymes, and cytokines. They interact with specific receptors or molecules in the body, modulating cellular processes, inhibiting or stimulating immune responses, or directly targeting disease-causing agents. The advantages of protein therapeutics lie in their high specificity, potency, and low toxicity. They often offer improved efficacy and fewer side effects than traditional small-molecule drugs. They have significantly advanced the field of medicine, providing novel treatment options and improving patient outcomes across various diseases.
The global market is majorly driven by the increasing focus on personalized medicine. In line with this, the rising research and development activities and the expanding healthcare infrastructure are significantly contributing to the market. Furthermore, the advancements in manufacturing processes are expected to fuel the market. Apart from this, the breakthroughs in genetic engineering, protein synthesis, and production technologies have enhanced the efficiency and effectiveness of protein therapeutics, positively influencing the market. Moreover, the growing prevalence of chronic diseases such as cancer, diabetes, cardiovascular disorders, and autoimmune diseases is catalyzing the market. Besides, the widespread applications of protein therapeutics in oncology are stimulating the market. Additionally, the rapid innovations in drug delivery systems have improved the delivery of protein therapeutics, enhancing their efficacy and patient compliance. Novel delivery methods such as sustained-release formulations, nanoparticles, and targeted drug delivery systems are driving the market growth by increasing the therapeutic potential of protein drugs.
Growing biopharmaceutical research and development investments
Biopharmaceutical companies and research institutions are increasingly focusing on the development of protein-based drugs due to their high specificity, efficacy, and targetability. The rise in R&D investments in the biopharmaceutical sector is fueling advancements in protein therapeutics. These investments support research activities related to protein engineering, drug discovery, and formulation optimization, leading to the development of novel and improved protein therapeutics. Furthermore, the substantial funds allocated to R&D enable researchers to explore new therapeutic targets, optimize protein structures for enhanced activity, and conduct extensive preclinical and clinical trials. These efforts contribute to the expansion of the market by introducing innovative treatments for various diseases. Moreover, the growing R&D investments facilitate the scaling-up of production processes for protein therapeutics, making them more accessible and cost-effective. This enables increased commercialization and market penetration of protein-based drugs.
Expansion of biosimilars
The expansion of the biosimilars market is significantly contributing to the market. Biosimilars are biologic drugs that are highly similar to approved reference protein therapeutics. As patents for several blockbuster biologics expire, the market for biosimilars is expanding rapidly. The availability of biosimilars provides cost-effective alternatives to expensive protein therapeutics, making them more accessible to patients and healthcare systems. This increased affordability enhances patient access to necessary treatments, driving market growth. Furthermore, the introduction of biosimilars fosters competition in the market. Competition leads to price reductions, encouraging market expansion and creating opportunities for biosimilar manufacturers and reference protein therapeutics companies to innovate and improve their products. Moreover, the regulatory frameworks and guidelines for biosimilars have become more established and streamlined, providing a clear pathway for their development and approval. This has instilled confidence in the healthcare community and resulted in increased biosimilar adoption. As the biosimilars market expands, it stimulates further research and development efforts in protein therapeutics. Manufacturers strive to develop more advanced and differentiated biosimilars, creating a positive outlook for the market.
Rising aging population
The rising aging population is positively influencing the market. As the global population ages, there is a higher prevalence of age-related diseases and conditions such as Alzheimer's disease, Parkinson's disease, macular degeneration, and osteoporosis. Protein therapeutics are being developed and utilized to address these specific health challenges the aging population faces. Furthermore, protein therapeutics offer targeted treatment options for age-related diseases, providing improved efficacy and reduced side effects as compared to traditional therapies. They can target specific molecular pathways and address the underlying mechanisms of these diseases, thereby improving patient outcomes and quality of life. Moreover, the increasing product demand among the aging population is driving market growth. Pharmaceutical companies and research institutions are investing in the development of novel protein therapeutics to meet the specific needs of this demographic. Additionally, the growing aging population creates a larger market for protein therapeutics, prompting manufacturers to expand their product portfolios and increase production. This, in turn, leads to a wider availability of protein therapeutics and further drives market growth.
IMARC Group provides an analysis of the key trends in each segment of the global protein therapeutics market report, along with forecasts at the global, regional and country levels from 2024-2032. Our report has categorized the market based on product, therapy area, and function.
Monoclonal Antibodies (mAbs)
Human Insulin
Erythropoietin
Clotting Factors
Fusion Protein
Others
Monoclonal Antibodies (mAbs) dominates the market
The report has provided a detailed breakup and analysis of the market based on product. This includes monoclonal antibodies (mAbs), human insulin, erythropoietin, clotting factors, fusion protein, and others. According to the report, monoclonal antibodies (mAbs) represented the largest segment.
Monoclonal antibodies (mAbs) are extensively used to treat cancer, autoimmune disorders, and inflammatory diseases. The increasing prevalence of these conditions, coupled with advancements in antibody engineering and production technologies, drives the demand for mAbs and contributes to the market growth.
On the other hand, human insulin is a vital protein therapeutic for managing diabetes. With the rising incidence of diabetes worldwide, the demand for insulin and insulin analogs is increasing, leading to market growth in this segment. Moreover, erythropoietin (EPO) is another important therapeutic protein stimulating red blood cell production. It is used to treat anemia, particularly in patients with chronic kidney disease and cancer undergoing chemotherapy. The expanding patient pool requiring EPO therapy is driving the growth of this segment.
Besides this, the clotting factors are proteins essential for blood clotting. They are used to manage bleeding disorders such as hemophilia. The growing awareness, diagnosis, and treatment of hemophilia fuel the demand for clotting factors and contribute to the market. In addition, fusion proteins, which combine two or more functional protein domains, have gained significant attention in the development of innovative therapeutics. They offer unique treatment approaches for various diseases, including cancer and autoimmune disorders, thus driving the market in this segment.
Metabolic Disorders
Immunological Disorders
Hematological Disorders
Cancer
Hormonal Disorders
Genetic Disorders
Others
Metabolic Disorders holds the largest share of the market
A detailed breakup and analysis of the market based on the therapy area have also been provided in the report. This includes metabolic disorders, immunological disorders, hematological disorders, cancer, hormonal disorders, genetic disorders, and others. According to the report, metabolic disorders accounted for the largest market share.
Metabolic disorders encompass conditions such as diabetes, obesity, and hypercholesterolemia. Protein therapeutics, such as insulin for diabetes management, are crucial in treating and controlling these disorders. The rising prevalence of metabolic disorders, coupled with the increasing demand for targeted and effective treatments, is driving the growth of the market in this segment.
On the contrary, immunological disorders, including autoimmune diseases and inflammatory conditions, represent another significant therapy area for protein therapeutics. Monoclonal antibodies and other protein-based drugs modulate the immune system and target specific disease pathways. The growing incidence of immunological disorders and the expanding range of approved protein therapeutics for these conditions are driving the market.
In addition, cancer remains one of the primary drivers of the market. Protein-based therapies, including monoclonal antibodies, antibody-drug conjugates, and immune checkpoint inhibitors, have revolutionized cancer treatment. The increasing incidence of cancer globally, coupled with the development of targeted therapies and immunotherapies, is propelling the growth of the market in oncology.
Enzymatic and Regulatory Activity
Special Targeting Activity
Vaccines
Protein Diagnostics
A detailed breakup and analysis of the market based on the function have also been provided in the report. This includes enzymatic and regulatory activity, special targeting activity, vaccines, and protein diagnostics.
Protein therapeutics with enzymatic and regulatory activity are vital in modulating biological processes and metabolic pathways. These proteins act as enzymes, receptors, or signaling molecules, offering therapeutic benefits in various diseases. The development of novel protein therapeutics with specific enzymatic or regulatory functions drives market growth in this segment.
Furthermore, special targeting activity refers to protein therapeutics targeting certain cells, tissues, or molecular targets. Monoclonal antibodies and antibody-drug conjugates are examples of protein therapeutics with special targeting activity. They can precisely recognize and bind to specific molecules or cells, providing highly targeted therapies. The increasing demand for targeted treatments in conditions such as cancer and autoimmune diseases fuels the growth of protein therapeutics in this segment.
Moreover, vaccines are another significant segment in the market. Protein-based vaccines utilize specific proteins or peptides to stimulate an immune response and confer immunity against infectious diseases. The global focus on vaccination programs, the emergence of new infectious diseases, and the need for improved vaccine technologies drive market growth in this segment.
Besides, protein diagnostics involves using proteins or protein-based assays for diagnostic purposes. These diagnostics can detect specific proteins or biomarkers associated with diseases, aiding in early detection, disease monitoring, and personalized treatment. The growing demand for accurate and reliable diagnostic tools fuels the growth of protein diagnostics and contributes to the overall market.
North America
United States
Canada
Asia Pacific
China
Japan
India
South Korea
Australia
Indonesia
Others
Europe
Germany
France
United Kingdom
Italy
Spain
Russia
Others
Latin America
Brazil
Mexico
Others
Middle East and Africa
North America exhibits a clear dominance, accounting for the largest protein therapeutics market share
The report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa.
North America, particularly the United States, holds a significant market share. The region benefits from advanced healthcare infrastructure, a strong presence of biopharmaceutical companies, and robust research and development activities. The presence of key players and extensive investments in protein therapeutics research contribute to market growth in North America. Additionally, the high prevalence of chronic diseases, a large aging population, and favorable reimbursement policies further drive the market in the region.
On the other hand, Asia Pacific is emerging as a rapidly growing market. The region has a large population base, increasing healthcare expenditure, and a rising prevalence of chronic diseases. Countries such as China, Japan, and India are witnessing substantial growth in the biopharmaceutical industry and investing in research and development. Moreover, the increasing awareness of personalized medicine and growing demand for cost-effective treatment options are driving the adoption of protein therapeutics in Asia Pacific.
Top companies are investing heavily in scientific research to identify new therapeutic targets and develop protein-based drugs with enhanced efficacy and safety profiles. They leverage their protein engineering, molecular biology, and biotechnology expertise to design and optimize therapeutic proteins. Furthermore, these companies establish strategic collaborations with academic institutions, research organizations, and other pharmaceutical companies to access new technologies, expand their pipelines, and accelerate development. Collaborations enable the exchange of knowledge, resources, and expertise, fostering innovation and driving the market. Moreover, successful commercialization strategies play a vital role in driving market growth. These companies employ robust marketing and sales efforts to promote and distribute their products to healthcare providers and patients worldwide. They conduct extensive clinical trials, generate compelling clinical data, and obtain regulatory approvals to ensure market access. Additionally, the top companies continuously invest in manufacturing capabilities and quality control systems to meet the growing demand and ensure a consistent supply of their products. This commitment to manufacturing excellence helps them meet the needs of patients, healthcare providers, and payers, further driving the market growth.
Amgen Inc.
Abbott Laboratories
Abbvie Inc.
Baxter International Inc.
Biogen Inc.
Csl Behring L.L.C. (CSL Limited)
Eli Lilly and Company
F. Hoffmann-La Roche AG (Roche Holding AG)
Johnson & Johnson
Merck & Co. Inc.
Novo Nordisk A/S (Novo Holdings A/S)
Pfizer Inc.
In 2020, Amgen Inc. entered into a collaboration with Adaptive Biotechnologies to develop and commercialize fully human-neutralizing antibodies targeting SARS-CoV-2, the virus that causes COVID-19.
In 2021, Abbott Laboratories received FDA clearance for their Tendyne Transcatheter Mitral Valve Replacement (TMVR) system, a minimally invasive therapy for patients with severe mitral regurgitation.
In 2020, AbbVie Inc. acquired Allergan, a pharmaceutical company known for its portfolio of aesthetic and therapeutic products, including Botox.