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2024-2032 年按产品类型、给药途径、疾病、应用和地区分類的疫苗佐剂市场报告Vaccine Adjuvants Market Report by Product Type, Route of Administration, Diseases, Application, and Region 2024-2032 |
2023年全球疫苗佐剂市场IMARC Group达9.965亿美元。由于传染病发病率上升、免疫学和疫苗技术的重大里程碑、对罕见疾病的认识不断提高、未建成人口对大流行疫苗接种工作的兴趣增加、政府支出迅速增长以及需求增加,全球疫苗佐剂市场正在快速成长。
疫苗和免疫学技术的进步
免疫学在疫苗佐剂的开发方面取得了重大进展,新佐剂比以前想像的更有效、更安全。技术进步使得能够设计出能够选择性增强对抗原的免疫反应的佐剂,从而显着提高疫苗对抗世界各地多种病原体的能力。最近,2024 年 2 月,艾伯维 (AbbVie) 和 Tentarix Biotherapeutics 宣布建立多年战略合作伙伴关係,共同开发肿瘤学和免疫学领域的生物候选药物。该协议价值超过6400万美元。候选药物的开发将结合艾伯维在肿瘤学和免疫学方面的能力与 Tentarix 的专有 Tentacles 平台,以发现和开发针对每个医学分支中的一个靶标的有条件活性的多特异性生物製剂。这将激活可以调节疾病途径的免疫细胞,同时减少通常与非特异性治疗相关的安全问题。
对罕见疾病的认识与理解不断提高
对罕见疾病的日益认识加速了疫苗开发的独特挑战。这种新的认识激起了人们对可以根据不同利益相关者的具体需求进行客製化的疫苗佐剂的兴趣。至于欧盟,他们将 RD 定义为欧洲人口中每 10 万人中受影响人数少于 50 人。然而,美国门诊孤儿药法案将 RD 定义为影响美国不到 20 万人。其他定义包括刚果每 10 万人中低至 5 人,而印度最高为每 10 万人中 76 人。平均而言,全球每 10 万人中就有 40 人受到 RD 影响。最近,根据 3,585 个 RD,罕见病患病率占世界人口的 3.5% 至 5.9%,相当于 263 至 4.46 亿人。
全球推动疫苗接种以应对流行病威胁
以新冠肺炎 (COVID-19) 为代表的对抗流行病威胁的斗争引发了一场史无前例的全球疫苗接种运动,推动疫苗佐剂市场成为优先公共卫生问题的焦点。此外,疫苗佐剂的主要用途是增强免疫反应、疫苗稳定性、提高疫苗效率和减少疫苗剂量,进而推动市场成长。 「根据ABC 新闻报道,每週新增15,141 例因COVID-19 入院的病例。根据美国疾病控制与预防中心(CDC) 的信息,这与2024 年4 月初的情况大致相同。但并不像以前那么高。根据美国疾病管制与预防中心 (CDC) 通报,在新冠病毒大流行期间,总共有超过 600 万美国人住院治疗。
IMARC Group提供了每个细分市场的主要趋势的分析,以及 2024-2032 年全球、区域和国家层面的预测。我们的报告根据产品类型、给药途径、疾病和应用对市场进行了分类。
助剂乳液占据大部分市场份额
该报告根据产品类型对市场进行了详细的细分和分析。这包括佐剂乳液、病原体成分、颗粒佐剂、组合佐剂等。根据该报告,佐剂乳液代表了最大的部分。
佐剂乳剂细分市场的推动因素是对具有增强功效和更持久免疫力的疫苗的需求不断增长。这种兴趣源于乳剂佐剂能够激发强烈而广泛的免疫反应,使其成为流感和 COVID-19 等复杂疾病的疫苗的理想选择。乳剂佐剂的多功能性与多种抗原相容,进一步增强了它们的吸引力。此外,奈米技术的进步改进了这些佐剂的递送机制,提高了它们的有效性,同时保持了安全性。旨在优化乳剂配方的持续研究和开发工作对于满足不断增长的疫苗佐剂市场需求至关重要,强调了它们在未来疫苗开发策略中的关键作用。
肌肉注射代表领先的细分市场
该报告根据给药途径对市场进行了详细的细分和分析。这包括口服、肌肉内、鼻内、皮下、皮内等。根据该报告,肌肉注射占最大部分。
肌肉注射细分市场的推动因素是对需要深入组织渗透才能获得最佳功效的疫苗的需求不断增长,例如针对流感、破伤风和 COVID-19 的疫苗。这种方法之所以受到青睐,是因为它能够将大量疫苗直接输送到血液供应丰富的肌肉中,促进更强、更快的免疫反应。此外,与其他方法相比,肌肉注射途径因其给药相对方便、不适感最小且不良反应风险较低而受到青睐,使其成为全球疫苗接种计划中广泛接受的做法。疫苗吸收率的一致性和支持其有效性的广泛历史资料进一步促进了其采用,突显了该领域的成长。
传染病占大部分市场份额
该报告根据疾病提供了详细的市场细分和分析。这包括癌症、传染病等。报告称,传染病占最大部分。
传染病领域是由全球流行病日益流行和新出现的传染病威胁所推动的,这凸显了对有效疫苗的迫切需求。国际旅行、都市化和气候变迁等因素导致传染病的传播,因此需要快速开发和部署含有强效佐剂的疫苗。政府和国际对抗传染病的倡议以及对研发的大量投资进一步推动了该领域的成长。此外,公众意识和医疗基础设施的改善在支持疫苗接种计划方面发挥着重要作用,从而增加了对有效对抗这些疾病的创新疫苗佐剂的需求。
研究代表了领先的细分市场
该报告根据应用程式提供了详细的市场细分和分析。这包括研究和商业。根据该报告,研究代表了最大的部分。
疫苗佐剂市场的研究领域受到对针对更广泛病原体(包括新出现和重新出现的传染病)的更有效疫苗的需求不断增长的推动。这种需求加上对免疫系统复杂性的日益了解,促使科学家探索能够引发更强、更持久免疫反应的新型佐剂配方。此外,针对个人基因组成的个人化医疗和疫苗的推动推动了对创新佐剂的探索。生物技术和奈米技术的进步进一步推动了这一领域的发展,使得能够开发出可以精确设计的下一代佐剂,以提高疫苗的有效性,同时最大限度地减少副作用。
北美市场领先,占据最大的疫苗佐剂市场份额
该报告还对所有主要区域市场进行了全面分析,其中包括北美(美国和加拿大);欧洲(德国、法国、英国、义大利、西班牙、俄罗斯等);亚太地区(中国、日本、印度、韩国、澳洲、印尼等);拉丁美洲(巴西、墨西哥等);以及中东和非洲。报告称,北美是疫苗佐剂最大的区域市场。
由于对疫苗研发(R&D)的大量投资,北美的疫苗佐剂预计将主导市场,这些疫苗旨在解决各种传染病以及公共和私营部门日益增长的健康问题。该地区具有疫苗审批流程快速的优势,这鼓励製药公司扩大和增加对辅助技术的投资。此外,北美拥有许多顶尖研究中心的优势,与生物技术领域的合作频繁。因此,它是医疗技术和创新领域。此外,为了提高疫苗的有效性,佐剂的使用越来越多地认识到提高疫苗的有效性和安全性的重要性,从而推动了北美市场的扩张。
(请注意,这只是关键参与者的部分列表,报告中提供了完整列表。)
The global vaccine adjuvants market size reached US$ 996.5 Million in 2023. Looking forward, IMARC Group expects the market to reach US$ 2,639.3 Million by 2032, exhibiting a growth rate (CAGR) of 11.1% during 2024-2032. Global vaccine adjuvants market is growing rapidly due to the rising incidence of infectious diseases, significant milestones in immunology and vaccine technology, the escalating awareness of rare disease, the increased interest in pandemic vaccination efforts among the unbuilt population, burgeoning government spending, and the need for effective vaccination for the elderly.
Advancements in Vaccine and Immunology Technology
Immunology has made significant strides in vaccine adjuvant development, with new adjuvants being both more effective and safer than previously thought. Technological progress allows to design adjuvants that can selectively increase immune response to an antigen, which significantly increased vaccines' capability to fight a wide range of pathogens around the world. Recently, in February 2024, AbbVie , and Tentarix Biotherapeutics revealed the multi-year strategic partnership to develop biologic candidates in oncology and immunology. The agreement is valued more than USD 64 million. The drug candidates will be developed to combine AbbVie's capabilities in oncology and immunology with Tentarix's proprietary Tentacles platform to discover and develop conditionally active, multi-specific biologics against one target in each branch of medicine. This will activate immune cells that can modulate disease pathways while reducing the safety concern, typically associated with non-specific treatment.
Rising Awareness and Understanding of Rare Diseases
The growing recognition for rare diseases has accelerated distinctive challenges in the vaccine development. This new awareness has piqued the interest in vaccine adjuvants that can be customized to the specific needs of various stakeholders. As regards to the European Union, they defined RDs as affecting less than 50 per 100,000 people in the European population. However, the American Orphan Drug Act, outpatient, defined RDs as affecting less than 200,000 people in the United States. Other definitions included one as low as 5 per 100,000 people in Congo, while the highest was 76 per 100,000 people in India . On average, RDs affects 40 in every 100,000 people in the world. Recently, the prevalence of Rare Diseases prevalence, based on 3,585 RDs, was between 3.5 to 5.9 percent of the world population, equaling 263 to 446 million individuals.
Global Push for Vaccinations Against Pandemic Threats
The fight against the threat of pandemics, exemplified by COVID-19, sparked an unprecedented global vaccination crusade, propelling the vaccine adjuvants market into the spotlight of priority public health concerns. Moreover, the key uses of vaccine adjuvants are enhancing immune response, vaccine stability, improving vaccine efficiency and reducing vaccines doses, which in turn is propelling the market growth. "There were 15,141 new weekly hospital admissions for COVID-19, according to the ABC news. That's about the same as in early April 2024, according to information from the Centers for Disease Control and Prevention (CDC). But it's not as high as the peak of 150,650 hospitalizations per week for the week of Jan. 22, 2022, during the omicron wave". In total, more than 6 million Americans have been hospitalized over the course of the pandemic, the CDC reports.
IMARC Group provides an analysis of the key trends in each segment of the market, along with forecasts at the global, regional, and country levels for 2024-2032. Our report has categorized the market based on product type, route of administration, diseases, and application.
Adjuvant Emulsions accounts for the majority of the market share
The report has provided a detailed breakup and analysis of the market based on the product type. This includes adjuvant emulsions, pathogen components, particulate adjuvants, combination adjuvants, and others. According to the report, adjuvant emulsions represented the largest segment.
The adjuvant emulsions segment is driven by the increasing demand for vaccines with enhanced efficacy and longer-lasting immunity. This interest stems from the ability of emulsion-based adjuvants to provoke a strong and broad immune response, making them ideal for use in vaccines against complex diseases such as influenza and COVID-19. The versatility of emulsion adjuvants, compatible with a wide range of antigens, further boosts their appeal. Additionally, advancements in nanotechnology have improved the delivery mechanisms of these adjuvants, increased their effectiveness while maintaining safety profiles. The ongoing research and development efforts aimed at optimizing emulsion formulations are crucial in meeting the growing vaccine adjuvants market demand, underscoring their pivotal role in future vaccine development strategies.
Intramuscular represents the leading market segment
The report has provided a detailed breakup and analysis of the market based on the route of administration. This includes oral, intramuscular, intranasal, subcutaneous, intradermal, and others. According to the report, intramuscular represented the largest segment.
The intramuscular segment is driven by the increasing demand for vaccines that require deep tissue penetration for optimal efficacy, such as vaccines against influenza, tetanus, and COVID-19. This method is preferred for its ability to deliver larger volumes of a vaccine directly into the muscle, where there is a rich blood supply, facilitating a stronger and quicker immune response. Additionally, the intramuscular route is favored for its relative ease of administration, minimal discomfort, and lower risk of adverse reactions compared to other methods, making it a widely accepted practice in vaccination programs globally. The consistency in vaccine absorption rates and the extensive historical data supporting its effectiveness further bolster its adoption, underlining the segment's growth.
Infectious diseases accounts for the majority of the market share
The report has provided a detailed breakup and analysis of the market based on the disease. This includes cancer, infectious diseases, and others. According to the report, infectious diseases represented the largest segment.
The infectious diseases segment is driven by the increasing prevalence of global pandemics and emerging infectious threats, which highlight the critical need for effective vaccines. Factors such as international travel, urbanization, and climate change contribute to the spread of infectious diseases, necessitating rapid development and deployment of vaccines with potent adjuvants. The segment's growth is further fueled by governmental and international initiatives to combat infectious diseases, alongside significant investments in research and development. Moreover, public awareness and healthcare infrastructure improvements play essential roles in supporting vaccination programs, thereby enhancing the demand for innovative vaccine adjuvants tailored to combat these diseases effectively.
Research represents the leading market segment
The report has provided a detailed breakup and analysis of the market based on the application. This includes research and commercial. According to the report, research represented the largest segment.
The research segment in the vaccine adjuvants market is driven by the increasing demand for more efficacious vaccines against a broader range of pathogens, including emerging and re-emerging infectious diseases. This need is coupled with a growing understanding of the immune system's complexities, prompting scientists to explore novel adjuvant formulations that can elicit stronger and more durable immune responses. Additionally, the push for personalized medicine and vaccines tailored to individual genetic makeups fuels the exploration of innovative adjuvants. Advances in biotechnology and nanotechnology further drive this segment, enabling the development of next-generation adjuvants that can be precisely engineered to enhance vaccine effectiveness while minimizing side effects.
North America leads the market, accounting for the largest vaccine adjuvants market share
The report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, North America represents the largest regional market for vaccine adjuvants.
The North America's vaccine adjuvants are expected to dominate the market due to extensive investment in researching and developing (R&D) vaccines that are aimed at tackling a wide range of infectious illnesses and rising health concerns from both the public and private sectors. The region has the advantage of a rapid approval process for vaccines, which encourages drug companies to expand and boost investments into adjuvant technologies. Furthermore, North America has many of the top research centers superiority and frequent collaboration with the biotech sector. As a result, it is the field of medical technology and innovation. In addition, to improve the effectiveness of vaccines, adjuvants, are used with greater awareness of the importance of boosting the effectiveness and safety of vaccines, driving market expansion in North America.
(Please note that this is only a partial list of the key players, and the complete list is provided in the report.)