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市场调查报告书
商品编码
1753880
2025-2033年核酸分离与纯化市场报告(依产品、类型、方法、最终使用者及地区)Nucleic Acid Isolation and Purification Market Report by Product, Type, Method, End User, and Region 2025-2033 |
2024年,全球核酸分离纯化市场规模达57亿美元。展望未来, IMARC Group预计到2033年,该市场规模将达到105亿美元,2025-2033年期间的复合年增长率(CAGR)为7.1%。分子诊断和研究需求的不断增长、自动化和高通量技术的进步、新冠疫情的影响以及医疗保健领域以外的应用不断扩展,是推动市场发展的主要因素。
核酸分离纯化是指从各种生物样本中分离并精製脱氧核糖核酸 (DNA) 或核糖核酸 (RNA) 分子的过程。这一关键步骤在分子生物学和诊断学中至关重要。在分离阶段,样本通常被裂解以释放核酸。随后,纯化步骤包括去除污染物、蛋白质和其他细胞成分,以获得适用于下游应用(包括聚合酶炼式反应 (PCR)、定序或分析)的纯核酸。常用的技术包括苯酚-氯仿萃取、管柱层析或磁珠法。
全球核酸分离纯化市场正经历强劲成长,这得益于医疗保健、生物技术和製药等各领域对分子诊断和基因研究的需求不断增长。同时,随着个人化医疗和基因组学研究的重要性不断提高,对高效能核酸分离纯化技术的需求也日益增长,为市场扩张创造了积极的前景。此外,自动化和高通量技术的重大进步简化了这些流程,减少了人工并提高了效率,从而促进了市场成长。此外,由于基于PCR的检测的广泛使用,COVID-19大流行推动了对核酸分离纯化产品的需求,从而有助于市场扩张。此外,市场参与者为提高产品性能和扩展应用领域而增加对研发(R&D)的投资,也促进了市场的成长。
分子诊断和基因研究的需求不断增加
推动核酸分离纯化市场发展的主要因素之一是分子诊断和基因研究需求的不断增长。在医疗保健领域,人们越来越重视个人化医疗,即利用基因资讯为个别患者制定个人化治疗方案。这一趋势刺激了对高效精准的核酸分离纯化方法的需求。同时,研究人员和临床医生需要高品质的DNA和RNA样本来进行各种分子检测,包括PCR、定序和基因表现分析。同样,生物技术和製药业也高度依赖核酸分离纯化来开发和测试新药、疫苗和疗法。这种跨多个领域的持续需求是市场成长的关键驱动力。
自动化和高通量技术的进步
推动市场成长的另一个重要因素是核酸分离纯化过程中自动化和高通量技术的不断进步。自动化系统和机器人平台的开发旨在简化和标准化这些流程,减少对人工的依赖,并最大限度地降低污染风险。同时,高通量仪器和方法使研究人员能够同时处理大量样本,从而提高效率和可扩展性。这些技术创新节省了时间,并提高了核酸分离纯化的可重复性和一致性,使其对寻求更高通量和更高精度的实验室和研究机构越来越有吸引力。
COVID-19疫情的影响
持续的COVID-19疫情对核酸分离纯化产业产生了重大影响。 PCR检测是诊断COVID-19的关键工具,其高度依赖病毒RNA的分离和纯化。 COVID-19检测需求的激增,以及研究和监测需求的增加,导致核酸分离纯化产品的使用量空前增长。市场参与者迅速适应此需求,扩大生产规模并开发用于SARS-CoV-2检测的专用试剂盒和试剂。儘管疫情的动态可能会随着时间的推移而发生变化,但人们对稳健的核酸分离纯化过程在传染病控制和研究中的重要性的认识不断提高,预计将对市场成长产生持久影响。
The global nucleic acid isolation and purification market size reached USD 5.7 Billion in 2024. Looking forward, IMARC Group expects the market to reach USD 10.5 Billion by 2033, exhibiting a growth rate (CAGR) of 7.1% during 2025-2033. The increasing demand in molecular diagnostics and research, automation and high-throughput technology advancements, the impact of the COVID-19 pandemic, and expanding applications beyond healthcare are some of the major factors propelling the market.
Nucleic acid isolation and purification refers to the processes employed in separating and refining deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) molecules from various biological samples. This essential step is crucial in molecular biology and diagnostics. The sample is typically lysed in the isolation phase to release nucleic acids. Subsequently, purification involves removing contaminants, proteins, and other cellular components to yield pure nucleic acids suitable for downstream applications, including polymerase chain reaction (PCR), sequencing, or analysis. Techniques such as phenol-chloroform extraction, column chromatography, or magnetic bead-based methods are commonly used.
The global nucleic acid isolation and purification market is experiencing robust growth driven by the increasing demand for molecular diagnostics and genetic research across various fields, including healthcare, biotechnology, and pharmaceuticals. In line with this, as the importance of personalized medicine and genomics research continues to rise, there is a surging need for efficient nucleic acid isolation and purification techniques, creating a positive outlook for market expansion. Moreover, significant advancements in automation and high-throughput technologies have streamlined these processes, reducing manual labor and improving efficiency, thereby fostering market growth. In addition to this, the COVID-19 pandemic has impelled the demand for nucleic acid isolation and purification products due to the extensive use of PCR-based testing, thereby aiding in market expansion. Furthermore, rising investments in research and development (R&D) by market players to enhance product performance and expand application areas are contributing to the market's growth.
Increasing demand for molecular diagnostics and genetic research
One of the primary factors driving the nucleic acid isolation and purification market is the growing demand for molecular diagnostics and genetic research. In the healthcare sector, there is a rising emphasis on personalized medicine, where genetic information is used to tailor treatments to individual patients. This trend has spurred the need for efficient and accurate nucleic acid isolation and purification methods. Concurrent with this, researchers and clinicians require high-quality DNA and RNA samples to perform various molecular tests, including PCR, sequencing, and gene expression analysis. Similarly, the biotechnology and pharmaceutical industries heavily rely on nucleic acid isolation and purification to develop and test new drugs, vaccines, and therapies. This sustained demand across multiple sectors is a key driving force behind the market's growth.
Advancements in automation and high-throughput technologies
Another significant factor fueling market growth is the continuous advancement of automation and high-throughput technologies in nucleic acid isolation and purification processes. Automation systems and robotic platforms have been developed to streamline and standardize these procedures, reducing the dependence on manual labor and minimizing the risk of contamination. In line with this, High-throughput instruments and methods enable researchers to process a larger number of samples simultaneously, improving efficiency and scalability. These technological innovations save time and enhance the reproducibility and consistency of nucleic acid isolation and purification, making them increasingly attractive to laboratories and research facilities seeking higher throughput and improved precision.
Impact of the COVID-19 pandemic
The ongoing COVID-19 pandemic has exerted a significant influence on the nucleic acid isolation and purification industry. PCR-based testing, a crucial tool for diagnosing COVID-19, relies heavily on the isolation and purification of viral RNA. The surge in demand for COVID-19 testing, along with the need for research and surveillance, has led to an unprecedented uptick in the utilization of nucleic acid isolation and purification products. Market players quickly adapted to meet this demand by scaling up production and developing specialized kits and reagents for SARS-CoV-2 detection. Although the pandemic's dynamics may change over time, the heightened awareness of the importance of robust nucleic acid isolation and purification processes in infectious disease control and research is expected to have a lasting impact on the market's growth.
Kits and reagents dominate the market
The demand for nucleic acid isolation and purification products, specifically kits and reagents, is propelled by the expanding application of nucleic acid-based techniques in the fields of forensic science and environmental monitoring. These areas increasingly rely on nucleic acid isolation and purification for DNA profiling, crime scene analysis, and identifying microbial contaminants. Additionally, the growing interest in agriculture and food safety drives the need for genetic testing and traceability, spurring demand for nucleic acid products. Apart from this, the emergence of innovative and specialized kits and reagents tailored to specific applications, such as RNA sequencing or viral RNA extraction, is attracting researchers and diagnostic labs, strengthening the market growth. Furthermore, the continuous development of user-friendly, cost-effective, and high-performance products accelerate the utilization of nucleic acid isolation and purification kits and reagents across various industries, providing impetus to the market growth.
Plasmid DNA isolation and purification holds the largest share in the market
The increasing importance of plasmid DNA in biotechnology and gene therapy applications is driving the demand for plasmid DNA isolation and purification. Plasmids are vital tools for genetic engineering, gene expression, and recombinant protein production, making them indispensable in the biopharmaceutical industry. Moreover, the rise of gene and cell therapies has created a surge in the demand for high-quality plasmid DNA for vector construction and therapeutic gene delivery, aiding in market expansion. Concurrent with this, the expanding field of synthetic biology, where custom-designed plasmids are employed to create novel biological systems, fuels the need for efficient plasmid DNA isolation and purification methods. The development of advanced purification techniques, such as chromatography and membrane-based systems, further enhances the purity and yield of plasmid DNA, making them essential components in the biotechnology and medical sectors and driving market demand.
Column-based isolation and purification dominates the market
The demand for nucleic acid isolation and purification, specifically through column-based methods, is fueled by the preference for column-based techniques in research and clinical laboratories due to their efficiency, simplicity, and scalability. These methods offer researchers a reliable and convenient means of isolating and purifying nucleic acids with high purity and yield. Additionally, the versatility of column-based systems enables their use across a wide range of applications, from fundamental research to diagnostics, impelling the market growth. Moreover, advancements in column technology, such as improved matrix materials and design, have led to enhanced performance and faster processing times, making them increasingly attractive to users seeking rapid and consistent results. Furthermore, the stringent quality control requirements in genomics, molecular diagnostics, and pharmaceuticals have led to the continued adoption of column-based nucleic acid isolation and purification methods, driving sustained demand in the market.
Hospitals and diagnostic centers hold the largest share in the market
The demand for nucleic acid isolation and purification products, particularly among hospital and diagnostic end-users, is primarily driven by the growing significance of molecular diagnostics in healthcare. Hospitals and diagnostic laboratories increasingly rely on nucleic acid-based tests to accurately diagnose various diseases, including infectious diseases, cancer, and genetic disorders. This has resulted in a consistent demand for high-quality DNA and RNA samples, thus fueling the need for efficient nucleic acid isolation and purification methods. Additionally, the rapid adoption of point-of-care testing and the emergence of novel diagnostic assays have amplified the demand for streamlined nucleic acid extraction processes that can be integrated into diagnostic workflows, thereby bolstering the market growth. As precision medicine gains prominence in patient care, hospitals are also utilizing nucleic acid purification techniques for personalized treatment strategies, propelling the market forward.
North America exhibits a clear dominance, accounting for the largest nucleic acid isolation and purification market share
The market research report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, North America accounted for the largest market share.
North America's well-established and advanced healthcare infrastructure, along with a robust presence of pharmaceutical and biotechnology companies, has created a significant demand for nucleic acid isolation and purification products. As precision medicine and genetic research gain momentum, the need for high-quality DNA and RNA samples in North America continues to rise, driving the market's growth. In addition to this, the increasing prevalence of chronic conditions such as cancer, infectious diseases, and genetic disorders in the region has led to an elevated demand for molecular diagnostics, further boosting the requirement for efficient nucleic acid isolation and purification methods. Furthermore, North America has been at the forefront of research and development in genomics, gene therapy, and biopharmaceuticals, contributing to the adoption of advanced purification techniques and specialized kits and reagents, thus playing a pivotal role in driving market expansion in the region.
The competitive landscape of the global nucleic acid isolation and purification market is characterized by intense rivalry among key players and a dynamic ecosystem of companies providing an array of products and services. Prominent companies dominate the market with their extensive product portfolios, global reach, and continuous investments in research and development. Additionally, a multitude of smaller and niche players cater to specialized segments and applications within the market, providing innovative solutions and fostering competition. Collaborations and partnerships between market players and research institutions are commonplace, further intensifying competition and driving innovation. As the market continues to expand, new entrants are attracted to its potential, contributing to a dynamic competitive landscape.