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哺乳动物多株抗体IgG 抗体市场报告(按类型、产品、应用、最终用途和地区)2025 年至 2033 年Mammalian Polyclonal IgG Antibody Market Report by Type, Product, Application, End Use, and Region 2025-2033 |
2024年,全球哺乳动物多株IgG抗体市场规模达11.418亿美元。展望未来, IMARC Group预计到2033年,该市场规模将达到17.026亿美元,2025-2033年期间的复合年增长率(CAGR)为4.31%。市场成长的驱动力包括:研究机构与行业参与者之间合作的不断加强、对单克隆和多克隆抗体研究的日益关注、全球医疗保健基础设施的不断扩大、自身免疫性疾病治疗应用的日益增长、重组抗体的日益普及以及合同研究组织(CRO)行业的显着增长。
哺乳动物多克隆免疫球蛋白 (IgG) 抗体是指透过接种各种哺乳动物(包括小鼠、兔子和山羊)而产生的抗原或疫苗。在此过程中,抗原透过注射注射到哺乳动物体内,以活化产生 IgG 的 B 淋巴细胞。这些抗体用于多种免疫测定测试的标记试剂,包括酵素连结免疫吸附试验 (ELISA)、蛋白质印迹试验、免疫放射测定 (IRMA) 和放射免疫测定 (RIA)。此外,该过程不需要熟练的专业人员来生产大批量疫苗。哺乳动物多克隆 IgG 抗体有助于开发多种治疗方法、诊断各种疾病以及进行抗体鑑定和流式细胞仪分析。因此,它们在生化研究中已广泛应用,用于检测变性蛋白质并研究疾病及其治疗方法。目前,它们已在市场上以心臟、代谢和肾臟标记产品的形式供应。
慢性病盛行率不断上升
癌症、心血管疾病和自体免疫疾病等慢性疾病病例的不断增加是哺乳动物多克隆IgG抗体市场规模扩张的主要因素。例如,根据28例全科医生记录的诊断,25岁及以上人群中至少患有一种慢性疾病的盛行率从2004年的34.9%上升到2011年的41.8%,在此期间显着增加了6.9个百分点。由于这些疾病需要更复杂的诊断和治疗,哺乳动物多克隆IgG抗体通常用于免疫测定、定向治疗和免疫系统调节。由于慢性疾病的持续增长,对相关抗体及其他解决方案的普遍需求推动了市场的进一步发展。
对治疗性抗体的需求不断增长
治疗性抗体需求的不断增长是扩大哺乳动物多克隆IgG抗体市场份额的关键因素。治疗性抗体因其高度特异性和有效靶向致病因子的能力,越来越多地用于治疗各种疾病,包括癌症、自体免疫疾病和传染病。随着生物製药公司开发更多基于抗体的疗法,对多克隆IgG抗体的需求也在不断增长,因为多克隆IgG抗体在免疫反应调节和研究应用中至关重要。此外,抗体工程的进步和对个人化医疗的日益关注进一步促进了治疗性抗体的应用。这种不断增长的需求推动了哺乳动物多克隆IgG抗体的研究、开发和生产,促进了市场的显着增长,并拓展了其在现代医疗保健中的应用。
生物技术和製药行业显着成长
生物技术和製药行业的成长是市场的重要驱动力。随着这些产业的扩张,涉及创新治疗和诊断解决方案的研发 (R&D) 活动的投资不断增加。多株抗体IgG 抗体在药物发现、疾病诊断和治疗开发中发挥关键作用,尤其是癌症和自体免疫疾病等复杂疾病。抗体工程等生物製药技术的不断进步,以及对生物製剂和生物仿製药的推动,也推动了对这些抗体的需求,从而导致这些抗体的产量增加和应用范围扩大。此外,该行业对个人化医疗和精准治疗的关注也增加了对高品质抗体的需求,进一步推动了市场的发展。
The global mammalian polyclonal IgG antibody market size reached USD 1,141.8 Million in 2024. Looking forward, IMARC Group expects the market to reach USD 1,702.6 Million by 2033, exhibiting a growth rate (CAGR) of 4.31% during 2025-2033. The market growth is driven by the increasing collaborations between research institutes and industry players, the rising focus on monoclonal and polyclonal antibody research, the expanding global healthcare infrastructure, the growing use in autoimmune disease treatment, the escalating adoption of recombinant antibodies, and significant growth of the contract research organization (CRO) industry.
Mammalian polyclonal immunoglobulins (IgG) antibody refers to antigens or vaccinations that are manufactured through inoculation of various mammals, including mice, rabbits, and goats. During this procedure, an antigen is administered via injectable into the mammal body to activate the B-lymphocytes that supply IgG. These antibodies are used in labeling reagents in multiple immunoassay tests, including enzyme-linked immunosorbent assay (ELISA), western blot tests, immunoradiometric assay (IRMA), and radioimmunoassay (RIA). Apart from this, the process does not require skilled professionals to produce large batches of vaccinations. Mammalian polyclonal IgG antibody helps create multiple therapeutics, diagnose various ailments, and perform antibody identification and flow cytometry. As a result, they find extensive applications in biochemical research to detect denatured proteins and examine diseases and their treatments. At present, they are commercially available in cardiac, metabolic, and renal marker product variants.
Increasing prevalence of chronic diseases
The increasing number of cases of chronic diseases, such as cancer, cardiovascular disease, and autoimmune diseases, is a major factor leading to the expansion of the mammalian polyclonal IgG antibody market size. For instance, the prevalence of individuals aged 25 and older with at least one chronic disease, based on 28 recorded diagnoses in general practice, rose from 34.9% in 2004 to 41.8% in 2011, reflecting a statistically significant increase of 6.9 percentage points during that period. As these conditions require more sophisticated diagnostics and management, mammalian polyclonal IgG antibodies are commonly used in immunoassays, directed therapy, and modulation of the immune system. Due to the persistent growth in chronic medical conditions, the prevalent need for relative antibody-based and other solutions contributes to the further advancement of the market.
Rising demand for therapeutic antibodies
The rising demand for therapeutic antibodies is a key factor augmenting the mammalian polyclonal IgG antibody market share. Therapeutic antibodies are increasingly used in the treatment of various diseases, including cancer, autoimmune disorders, and infectious diseases, due to their high specificity and ability to target disease-causing agents effectively. As biopharmaceutical companies develop more antibody-based therapies, the demand for polyclonal IgG antibodies, which are essential in immune response modulation and research applications, is growing. Additionally, advancements in antibody engineering and an increased focus on personalized medicine further enhance the adoption of therapeutic antibodies. This rising demand fuels research, development, and production of mammalian polyclonal IgG antibodies, contributing to significant market growth and expanding their applications in modern healthcare.
Significant growth in the biotechnology and pharmaceutical industries
The growth of the biotechnology and pharmaceutical industries is a significant driver of the market. As these industries expand, there has been increasing investments in research and development (R&D) activities involving innovative therapeutic and diagnostic solutions. Polyclonal IgG antibodies play a critical role in drug discovery, disease diagnostics, and therapeutic development, especially for complex diseases like cancer and autoimmune disorders. Continual advancements in biopharmaceutical technologies, such as antibody engineering, and the push for biologics and biosimilars are also driving the demand for these antibodies, leading to increased production and wider applications for these antibodies. Additionally, the industry's focus on personalized medicine and precision therapies increases the need for high-quality antibodies, further providing a boost to the market.