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市场调查报告书
商品编码
1753989
2025 年至 2033 年乳癌液体活检市场报告(按产品服务、循环生物标记(循环肿瘤细胞、游离 DNA、细胞外囊泡等)、最终用户和地区划分)Breast Cancer Liquid Biopsy Market Report by Product Services, Circulating Biomarker (Circulating Tumor Cells, Cell-Free DNA, Extracellular Vesicles, and Others), End User, and Region 2025-2033 |
2024年,全球乳癌液体切片市场规模达1.507亿美元。展望未来, IMARC Group预计到2033年,该市场规模将达到5.534亿美元,2025-2033年期间的复合年增长率(CAGR)为14.77%。乳癌盛行率的上升、向非侵入性诊断方法的转变、技术的持续进步以及癌症研究投入的激增,是推动市场成长的主要因素。
乳癌发生率不断上升
全球乳癌盛行率的上升是主要驱动因素之一。例如,根据世界卫生组织 (WHO) 的数据,2022 年全球将有近 230 万名女性被诊断出罹患乳癌,约有 67 万名女性死亡。同样,根据美国国家乳癌基金会的数据,在美国,每 8 名女性中就有 1 名在其一生中会被诊断出罹患乳癌。到 2024 年,预计将有 310,720 名女性和 2,800 名男性被诊断出患有侵袭性乳癌。由于乳癌仍然是全球女性中最常见的癌症之一,对液体活检等早期检测和监测解决方案的需求正在上升。预计这些因素将在未来几年推动乳癌液体活检市场份额的成长。
注重早期检测
乳癌的早期发现可显着改善患者的预后,而液体活检比一些传统的影像方法能够更早发现。例如,根据美国国家医学图书馆发表的一篇文章,液体活检已显示出在早期诊断癌症、追踪肿瘤生长和復发以及预测患者治疗反应的潜力。它还能实现持续监测,这对于追踪病情进展和治疗反应至关重要,使其成为现代肿瘤学的重要工具。这些因素进一步对乳癌液体活检市场预测产生了积极影响。
产品创新
基因组定序、分子生物学和生物资讯学领域的创新正在提高液体活检技术的灵敏度、特异性和准确性。例如,2023年11月,DNA定序和基于阵列的技术公司Illumina Inc.开发了其分散式液体活检检测方法的改进版本,用于基因组分析。新的TruSight Oncology 500 ctDNA v2(TSO 500 ctDNA v2)是一种研究检测方法,可对血液中的循环肿瘤DNA (ctDNA) 进行非侵入性全面基因组分析 (CGP)。这些进步有助于早期癌症检测、疗效监测和抗药性突变识别,从而推动液体活检在临床环境中的应用,从而促进乳癌液体活检市场的成长。
The global breast cancer liquid biopsy market size reached USD 150.7 Million in 2024. Looking forward, IMARC Group expects the market to reach USD 553.4 Million by 2033, exhibiting a growth rate (CAGR) of 14.77% during 2025-2033. The rising prevalence of breast cancer, shift towards non-invasive diagnostic methods, ongoing technological advancements, and surging investment in cancer research, are primarily driving the market's growth.
Increasing Prevalence of Breast Cancer
The increasing global prevalence of breast cancer is one of the primary drivers. For instance, according to the World Health Organization (WHO), in 2022, nearly 2.3 million women were diagnosed with breast cancer, and approximately 670,000 died worldwide. Similarly, according to the National Breast Cancer Foundation, in the United States, 1 out of every 8 women will be diagnosed with breast cancer during their lifetime. In 2024, an estimated 310,720 women and 2,800 males will be diagnosed with invasive breast cancer. As breast cancer remains one of the most common cancers among women worldwide, the demand for early detection and monitoring solutions, like liquid biopsy, is rising. These factors are expected to propel the breast cancer liquid biopsy market share in the coming years.
Focus on Early Detection
Early detection of breast cancer significantly improves patient outcomes, and liquid biopsy allows for earlier detection than some traditional imaging methods. For instance, according to an article published by the National Library of Medicine, LB has demonstrated potential in diagnosing cancer at an early stage, tracking tumor growth and recurrence, and predicting patient response to therapy. It also enables continuous monitoring, which is essential for tracking disease progression and treatment response, making it an essential tool in modern oncology. These factors further positively influence the breast cancer liquid biopsy market forecast.
Product Innovations
Innovations in genomic sequencing, molecular biology, and bioinformatics are enhancing the sensitivity, specificity, and accuracy of liquid biopsy techniques. For instance, in November 2023, Illumina Inc., a DNA sequencing and array-based technology business, developed an improved version of their distributed liquid biopsy assay for genomic profiling. The new TruSight Oncology 500 ctDNA v2 (TSO 500 ctDNA v2) is a research assay that allows for non-invasive comprehensive genomic profiling (CGP) of circulating tumor DNA (ctDNA) from blood. These advancements help in early cancer detection, monitoring treatment efficacy, and identifying resistance mutations, which drives the adoption of liquid biopsy in clinical settings, thereby boosting the breast cancer liquid biopsy market growth.
Currently, reagent kits account for the majority of the global market share
According to the breast cancer liquid biopsy market outlook, the increasing global incidence of breast cancer has heightened the need for better diagnostic, monitoring, and screening tools. As liquid biopsy becomes more commonly used, the demand for reagent kits that support these tests rises proportionally. Moreover, traditional tissue biopsies are invasive and can cause discomfort and complications. Liquid biopsy offers a non-invasive alternative, which is gaining popularity for both diagnostic and treatment monitoring purposes. This shift is a key driver for reagent kits used in liquid biopsy procedures, such as those for detecting circulating tumor DNA (ctDNA) or circulating tumor cells (CTCs).
According to the breast cancer liquid biopsy market analysis report, CTCs are cancer cells that have shed from the primary tumor into the bloodstream. The presence of CTCs in the blood correlates with disease stage and prognosis. Higher numbers of CTCs are often associated with advanced cancer and poorer outcomes. Moreover, cfDNA consists of small fragments of DNA released from tumor cells (also referred to as circulating tumor DNA or ctDNA) and other cells into the bloodstream. Moreover, analysis of cfDNA allows for the detection of specific mutations, such as those in the PIK3CA gene, TP53, or ESR1, which can guide treatment choices, especially for targeted therapies. Furthermore, extracellular vesicles (such as exosomes and microvesicles) are small membrane-bound particles released by cells, including cancer cells, into the bloodstream. EVs contain a variety of biomolecules, including proteins, RNA, DNA, and lipids, and can play a role in cell-to-cell communication.
According to the breast cancer liquid biopsy market outlook report, reference labs often have access to the most cutting-edge technologies in liquid biopsy, including next-generation sequencing (NGS) and circulating tumor DNA (ctDNA) analysis. Their advanced infrastructure attracts demand from hospitals and physician labs that do not have these capabilities. Moreover, large hospitals, especially those with dedicated oncology centers, have a high volume of breast cancer patients requiring regular monitoring. Liquid biopsy offers a less invasive, faster alternative to traditional tissue biopsies for diagnosis, treatment monitoring, and recurrence detection. Furthermore, physical labs are often the first point of care for breast cancer screening. Liquid biopsies provide a more accessible and less invasive option for patients at high risk of breast cancer, allowing for earlier detection and intervention.
North America currently dominates the global market
The report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, North America dominates the global market.
According to the breast cancer liquid biopsy market statistics, breast cancer remains one of the most common cancers among women in North America, driving demand for improved diagnostic tools. Moreover, liquid biopsies offer a non-invasive alternative to traditional tissue biopsies, which can be painful, risky, and difficult to perform, especially in advanced cancer cases. As a simple blood test, liquid biopsy is more appealing to patients, contributing to its growing adoption. Besides this, advances in liquid biopsy technologies, including next-generation sequencing (NGS), PCR-based methods, and improved ctDNA and CTC (circulating tumor cells) detection platforms, have significantly increased the accuracy and sensitivity of these tests. These innovations are driving wider clinical adoption of liquid biopsy for breast cancer diagnosis and monitoring.