![]() |
市场调查报告书
商品编码
1800791
预装色谱管市场报告(按类型、技术、应用、最终用途和地区)2025-2033Prepacked Chromatography Columns Market Report by Type, Technique, Application, End-Use, and Region 2025-2033 |
2024年,全球预载层析柱市场规模达22亿美元。展望未来, IMARC Group预计到2033年,该市场规模将达到39亿美元,2025-2033年期间的复合年增长率(CAGR)为6.3%。各种慢性疾病的发生率不断上升,疾病管理对生物製药的需求不断增长,以及各行各业对层析柱应用的不断增加,是推动市场成长的主要因素。
生物製药需求增加
癌症、糖尿病、心血管疾病和自体免疫疾病等各种慢性疾病的盛行率不断上升,推动着市场的成长。再加上对疾病管理用生物製药的需求不断增长,这些因素共同促进了市场的成长。根据美国国立卫生研究院 (NIH) 的数据,预计 2022 年印度癌症发生率为 14,61,427 例(粗发病率:每 10 万人中有 100.4 例)。在儿童 (0-14 岁) 癌症中,淋巴球白血病(男孩:29.2%,女孩:24.2%)是主要发病部位。预计 2025 年癌症发生率将比 2020 年增加 12.8%。例如,IDF 糖尿病图集(2021 年)报告称,10.5% 的成年人口(20-79 岁)患有糖尿病,其中近一半的人不知道自己患有糖尿病。 IDF 预测显示,到 2045 年,每八名成年人中就有一人患有糖尿病,约 7.83 亿人,增幅达 46%。这将对预装层析柱市场统计数据产生重大影响。
色谱技术的重大进步
色谱技术的不断进步也推动着市场的发展。例如,包括高效液相层析 (HPLC) 和亲和色谱在内的色谱技术的持续创新正在提高分离的效率、速度和分辨率。色谱法在环境检测中的广泛应用正在影响市场的成长。例如,2023 年 6 月,安捷伦科技公司宣布推出两款新型液相层析质谱系统 (LCMS):Agilent 6495D LC/TQ 和 Agilent Revident LC/Q-TQF。为了提升 Revident LC/Q-TQF 的高阶效能,安捷伦也宣布推出全新的 Agilent MassHunter Explorer Profiling 软体和 Agilent ChemVistra 库管理器软体。预计这将推动未来几年预装色谱柱市场的成长。
生物加工和一次性技术日益受到重视
生物製药和生物技术行业日益关註一次性技术,以简化生产流程并降低交叉污染风险,这促进了市场的成长。一次性预包装柱无需批次间的清洁和验证步骤,从而优化了宝贵的生产时间,从而提高了生产效率和成本效益。例如,2023年9月,专注于生物製程技术领导地位的生命科学公司Repligen Corporation宣布已达成最终协议,收购位于瑞典默恩达尔的私人控股公司Metenova AB(简称Metenova)。 Metenova预计在2023财年实现2,400万至2,500万美元的收入,这主要得益于其磁力混合和传动系统技术的成功,这些技术已被全球生物製药公司和合约开发与生产组织(CDMO)广泛应用。该公司近期推出MixOne平台,进军一次性混合市场,并充分利用其现有不锈钢(重复使用)产品线的成功经验。
>1000 ML 占据大部分市场份额
不同行业对大尺寸色谱柱的偏好日益增长,这推动了该细分市场的发展。 >1000 毫升预装柱通常用于纯化生物分子,例如单株抗体、蛋白质和疫苗。它们有助于实现高容量层析分离,确保生产出纯度高、品质优良的生物製药产品。此外,食品和饮料 (F&B) 製造商使用>1000 毫升预装柱进行风味提取、品质控制以及糖、氨基酸和着色剂等成分的分离等任务。这些色谱柱有助于实现稳定的产品品质并符合食品安全法规。在化学研发 (R&D) 领域,这些色谱管柱对于化合物的合成和纯化至关重要。研究人员可以有效地扩大色谱流程,节省时间和资源,同时确保产品纯度。
离子交换层析法占大部分市场份额
离子交换层析法用途广泛,可应用于多种生物分子,包括蛋白质、核酸和其他带电分子。这种适应性使其适用于各种研究和工业应用。此外,它还能根据待分离分子的电荷提供优异的选择性。透过使用具有不同官能基的离子交换树脂,研究人员可以从复杂混合物中有效地分离和纯化目标分子。此外,它还能提供高解析度分离,从而能够分离电荷性质不同的近缘物种。此外,它易于规模化生产,适用于生物製药、食品加工和其他行业的大规模纯化製程。
样品製备占据最大的市场份额
样品製备是色谱分析的基本前提,推动了色谱分析市场的成长。它涉及从复杂样品中提取、净化和浓缩目标分子,确保只有相关化合物到达色谱柱。样品製备的品质直接影响后续色谱分析的准确性和灵敏度,因此至关重要。此外,包括製药、生物技术、食品饮料、环境监测和医疗保健在内的众多行业都严重依赖色谱分析进行品质控制、研究和产品开发。此外,高效液相层析 (HPLC) 和质谱 (MS) 等分析技术的持续发展,要求样品製备方法能够满足不断变化的需求。
製药和生物技术公司占据最大的市场份额
製药和生物技术公司必须遵守严格的监管要求,以确保其产品的安全性和有效性,这进一步推动了该细分市场的快速成长。色谱法是一种可靠且标准化的化合物表征和纯化方法,预装管柱是实现合规性和保持生产一致性的理想选择。此外,包括单株抗体和基因疗法在内的生物製药领域的不断进步,也导致了针对这些复杂分子的专用色谱柱的需求不断增长。此外,这些产业在药物开发、生产和品质控制的各个阶段都依赖对蛋白质、抗体和核酸等生物分子进行精确且高效的分离和纯化。预装色谱管柱提供了即用型解决方案,可显着简化这些流程,从而降低时间和人工成本。
北美引领市场,占据最大的预装层析柱市场份额
该报告还对所有主要区域市场进行了全面分析,包括北美(美国和加拿大);欧洲(德国、法国、英国、义大利、西班牙、俄罗斯等);亚太地区(中国、日本、印度、韩国、澳洲、印尼等);拉丁美洲(巴西、墨西哥等);以及中东和非洲。报告指出,北美是预装层析柱最大的区域市场。
北美拥有众多从事药物发现、开发和生产的製药和生物技术公司,这推动了市场的成长。此外,北美的製药和生物技术产业受到美国食品药物管理局 (FDA) 和加拿大卫生部製定的严格监管标准的约束。除此之外,色谱柱製造业的几家主要参与者的总部或在北美拥有重要的业务。关键产业参与者的集中促进了竞争、创新和广泛的产品供应。此外,该地区拥有先进的医疗保健基础设施,包括尖端的诊断实验室和医疗保健设施。色谱法广泛应用于临床诊断和研究,进一步刺激了对预装柱的需求。例如,2024 年 2 月,岛津製作所从 Activated Research Company, LLC(美国明尼苏达州 ARC)收购了气相层析 (GC) 催化微反应业务。
(请注意,这只是关键参与者的部分列表,完整列表在报告中提供。)
The global prepacked chromatography columns market size reached USD 2.2 Billion in 2024. Looking forward, IMARC Group expects the market to reach USD 3.9 Billion by 2033, exhibiting a growth rate (CAGR) of 6.3% during 2025-2033. The growing prevalence of various chronic diseases, the rising demand for biopharmaceuticals for disease management, and increasing utilization of chromatography across various industries are some of the major factors propelling the growth of the market.
Increased Demand for Biopharmaceuticals
The rising prevalence of various chronic diseases including cancer, diabetes, cardiovascular disorders, and autoimmune conditions is driving the growth of the market. This, coupled with the escalating demand for biopharmaceuticals for disease management is strengthening the growth of the market. According to NIH, the estimated number of incident cases of cancer in India for the year 2022 was found to be 14,61,427 (crude rate:100.4 per 100000). Among the childhood (0-14 yr) cancers, lymphoid leukemia (boys: 29.2% and girls: 24.2%) was the leading site. The incidence of cancer cases is estimated to increase by 12.8% in 2025 as compared to 2020. For instance, IDF Diabetes Atlas (2021) reports that 10.5% of the adult population (20-79 years) has diabetes, with almost half unaware that they are living with the condition. By 2045, IDF projections show that one in eight adults approximately 783 million, will be living with diabetes an increase of 46%. This is infleuncing the prepacked chromatography columns market statistics significantly.
Significant Technological Advancement in Chromatography
The market is also driven by continuous advancements in chromatography technology. For instance, ongoing innovations in chromatographic techniques including high-performance liquid chromatography (HPLC) and affinity chromatography are improving the efficiency, speed, and resolution of separation. The widespread adoption of chromatography in environmental testing is influencing the growth of the market. For instance, in June 2023, Agilent Technologies Inc. announced two new liquid chromatography-mass spectrometry systems (LCMS), the Agilent 6495D LC/TQ and the Agilent Revident LC/Q-TQF. Facilitating the high-end performance of the Revident LC/Q-TQF, Agilent is also announcing the new Agilent MassHunter Explorer Profiling software and the new Agilent ChemVistra library manager software. This is expected to fuel the prepacked chromatography columns market forecast over the coming years.
Rising Emphasis on Bioprocessing and Single-Use Technologies
The increasing focus of biopharmaceutical and biotechnology industries towards single-use technologies to streamline production and reduce cross-contamination risk is contributing to the growth of the market. Single-use prepackaged columns optimize the use of valuable production time by eliminating the need for cleaning and validation steps between batches which leads to more efficient and cost-effective manufacturing. For instance, in September 2023, Repligen Corporation, a life sciences company focused on bioprocessing technology leadership, announced that it has entered into a definitive agreement to acquire privately held Metenova AB (Metenova) of Molndal, Sweden. Metenova is projected to generate revenues of $24 million to $25 million for fiscal year 2023, led by the success of its magnetic mixing and drive train technologies that are widely used by global biopharmaceutical companies and contract development and manufacturing organizations (CDMOs). The company recently entered the single-use mixing market with the launch of its MixOne platform, leveraging the success of its existing stainless steel (repeat-use) product line.
>1000 ML accounts for the majority of the market share
The rising preference for large column sizes across different industry verticals is driving the market segment. >1000 ML prepacked columns are commonly employed for the purification of biomolecules such as monoclonal antibodies, proteins, and vaccines. They facilitate high-capacity chromatographic separations, ensuring the production of pure and high-quality biopharmaceutical products. Additionally, food and beverage (F&B) manufacturers utilize >1000 mL prepacked columns for tasks like flavor extraction, quality control, and the separation of components like sugars, amino acids, and colorants. These columns aid in achieving consistent product quality and compliance with food safety regulations. In chemical research and development (R&D), these columns are essential for synthesizing and purifying compounds. Researchers can scale up their chromatographic processes efficiently, saving time and resources while ensuring product purity.
Ion-exchange chromatography holds the majority of the market share
Ion-exchange chromatography is versatile and can be applied to a wide range of biomolecules, including proteins, nucleic acids, and other charged molecules. This adaptability makes it suitable for various research and industrial applications. Additionally, it offers excellent selectivity based on the charge of the molecules being separated. By using ion-exchange resins with different functional groups, researchers can effectively separate and purify target molecules from complex mixtures. Apart from this, it provides high-resolution separation, enabling the isolation of closely related species with different charge properties. Furthermore, it can be easily scaled up for industrial production, making it suitable for large-scale purification processes in biopharmaceuticals, food processing, and other industries.
Sample preparation represents the largest market segment
Sample preparation is a fundamental prerequisite for chromatographic analyses which is fueling the segment growth in the market. It involves the extraction, clean-up, and concentration of target molecules from complex samples, ensuring that only relevant compounds reach the chromatography columns. The quality of sample preparation directly influences the accuracy and sensitivity of subsequent chromatographic analyses, making it an essential step. Additionally, diverse industries, including pharmaceuticals, biotechnology, food and beverage, environmental monitoring, and healthcare, heavily rely on chromatography for quality control, research, and product development. Furthermore, ongoing advancements in analytical techniques, such as high-performance liquid chromatography (HPLC) and mass spectrometry (MS), demand sample preparation methods that can cater to evolving needs.
Pharmaceutical and biotechnology companies account for the largest market share
Pharmaceutical and biotechnology companies are subject to rigorous regulatory requirements to ensure the safety and efficacy of their products which is further driving the segment growth in the market. Chromatography is a trusted and standardized method for characterizing and purifying compounds, making prepacked columns an attractive option for achieving compliance and maintaining consistency in manufacturing. Moreover, the continuous advancements in biopharmaceuticals, including monoclonal antibodies and gene therapies, have led to increased demand for specialized chromatography columns tailored to these complex molecules. Furthermore, these industries rely on precise and efficient separation and purification of biomolecules, such as proteins, antibodies, and nucleic acids, at various stages of drug development, production, and quality control. Prepacked chromatography columns offer ready-to-use solutions that significantly streamline these processes, reducing time and labor costs.
North America leads the market, accounting for the largest prepacked chromatography columns market share
The report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, North America represents the largest regional market for prepacked chromatography columns.
North America is home to numerous pharmaceutical and biotechnology companies engaged in drug discovery, development, and production which is driving the market growth. Additionally, pharmaceutical and biotechnology sectors in North America are subject to strict regulatory standards set by the U.S. Food and Drug Administration (FDA) and Health Canada. Apart from this, several major players in the chromatography column manufacturing industry are headquartered or have a significant presence in North America. This concentration of key industry players fosters competition, innovation, and a wide range of product offerings. Furthermore, the region boasts advanced healthcare infrastructure, including cutting-edge diagnostic laboratories and healthcare facilities. Chromatography is extensively used in clinical diagnostics and research, further fueling the demand for prepacked columns. For instance, in February 2024, Shimadzu Corporation acquired the catalytic micro-reactive business for gas chromatography (GC) from Activated Research Company, LLC (ARC, Minnesota, USA).
(Please note that this is only a partial list of the key players, and the complete list is provided in the report.)