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市场调查报告书
商品编码
1820001
2025 年至 2033 年脊椎生物製剂市场报告(按产品、手术类型、最终用户和地区)Spine Biologics Market Report by Product, Surgery Type, End User, and Region 2025-2033 |
2024年,全球脊椎生物製剂市场规模达21.4亿美元。展望未来, IMARC Group预计到2033年,市场规模将达到29.7亿美元,2025-2033年期间的复合年增长率(CAGR)为3.52%。推动市场发展的因素包括:微创手术(MIS)的广泛应用、老年人口的成长、收入水准提高带来的医疗服务可近性的提升,以及脊椎疾病发生率的上升。
脊椎疾病盛行率不断上升
脊椎疾病的日益增加影响着脊椎生物製剂市场的成长。此外,预期寿命的延长和生活方式的问题也刺激了椎间盘疾病和椎管狭窄等退化性疾病的发展。根据世界卫生组织 (WHO) 的数据,2020 年大约每 13 个人中就有 1 人(相当于 6.19 亿人)患有腰痛 (LBP),比 1990 年增加了 60%。据进一步估计,到 2050 年,腰痛病例将增加约 8.43 亿,凸显了脊椎问题的普遍性。 80 岁年龄层的发生率不断上升,而 50-55 岁年龄层的 LBP 病例数则不断增加。这种普遍的盛行率需要持续开发和部署有效的治疗方法,包括生物製剂,这有助于促进骨骼生长和癒合,使其成为治疗这些普遍存在的疾病的关键。
微创手术(MIS)的采用率不断上升
与传统的开放式手术相比,微创手术 (MIS) 因其痛苦小、恢復快而成为治疗脊椎疾病的首选。根据 IMARC 集团的数据,预计 2024 年至 2032 年期间,全球微创手术市场将以约 6% 的年复合成长率(CAGR) 扩张。 2023 年,该市场规模达到 529 亿美元,预计到 2032 年将达到 910 亿美元。这一增长表明手术方法的转变,从而缩短了住院时间和恢復期,这对脊椎生物製剂的市场价值尤其有利。
老年人口不断增加
老年人口的成长推动了脊椎生物製剂市场的需求。随着年龄的增长,脊椎疾病的风险也会增加,因此需要更频繁、更深入的照护。根据联合国的资料,预计65岁及以上人口的比例将从2022年的10%上升到2050年的16%。预计到2050年,全球65岁及以上人口的数量将是5岁以下儿童数量的两倍,相当于12岁儿童的数量。这意味着与年龄相关的脊椎疾病数量将持续增加,对有效且微创的治疗方法的需求也随之增加。例如,有助于自然癒合过程的生物製剂尤其适合满足这些需求,符合全球老化人口日益增长的医疗保健需求。
骨移植替代品占大部分市场份额
骨移植替代品是传统骨移植的替代方案,可在脊椎手术中提供结构支撑并促进骨癒合。这些替代品包括合成材料、同种异体骨和脱矿骨基质,因其能够促进骨融合、减少从患者自身取骨的需求、最大限度地减少手术併发症和缩短恢復时间而备受推崇。根据IMARC GROUP的数据,全球骨移植和替代品市场规模在2023年达到32亿美元。预计到2032年将达到51亿美元,2024-2032年期间的年复合成长率(CAGR)为5.2%。此外,生物材料、再生医学和骨移植替代品领域的各项进步正见证着其在脊椎手术中的应用日益广泛,从而积极提升了脊椎生物製品市场的价值。
微创脊椎手术占据业界最大份额
微创脊椎手术的兴起主要归功于患者和医护人员对微创手术的日益青睐。与传统的开放式手术相比,微创脊椎手术具有许多优势,包括切口较小、出血量较少、住院时间较短、恢復较快。因此,它在治疗各种脊椎疾病方面广受欢迎,例如退化性椎间盘疾病、椎间盘突出、椎管狭窄和椎体骨折。根据美国国家医学图书馆的数据,随着影像导航系统、机器人技术和内视镜技术的进步,微创脊椎 (MIS) 手术取得了显着进展。美国每年完成的微创脊椎手术超过 40 万例,其中脊椎融合术是治疗脊椎创伤、肿瘤、结构畸形和退化性疾病的常用且成熟的治疗方案。
医院是主要的细分市场
医院是主要的专科医疗中心,吸引了大量寻求各种脊椎疾病(包括需要手术治疗的疾病)的患者。此外,一些医院设有专门的脊椎中心或科室提供服务,使其成为提供全面护理的首选中心。此外,医院与脊椎生物製剂製造商和供应商保持着密切的合作,从而提高了设备的效率。 2022年6月,Xenco Medical 获得美国食品药物管理局 (FDA) 的批准,并推出了一次性使用的多节段颈椎手术套件 (Multilevel CerviKit),从而扩大了其面向门诊手术中心的设备范围。该套件包含一整套用于颈椎前路两节段、三节段和四节段手术的植入物和一次性器械。
北美引领市场,占据脊椎生物製剂最大市场份额
该报告还对所有主要区域市场进行了全面分析,包括北美(美国和加拿大);欧洲(德国、法国、英国、义大利、西班牙、俄罗斯等);亚太地区(中国、日本、印度、韩国、澳洲、印尼等);拉丁美洲(巴西、墨西哥等);以及中东和非洲。报告指出,北美是脊椎生物製剂最大的区域市场。
北美在市场上的主导地位可以归因于高度发展的医疗基础设施、创新医疗技术的高采用率以及庞大的脊椎疾病患者群体。例如,根据美国国家脊髓损伤协会的资料,美国约有 45 万人患有脊髓损伤 (SCI)。美国每年估计有 17,000 例新发生 SCI 病例,主要源自于脊椎创伤。因此,SCI 族群发病率的上升显着增加了该地区对治疗脊椎疾病的生物製剂的需求。此外,优惠的报销政策、强大的研发力度以及对微创手术优势的认识,正在为北美脊椎生物製剂市场带来收入。
The global spine biologics market size reached USD 2.14 Billion in 2024. Looking forward, IMARC Group expects the market to reach USD 2.97 Billion by 2033, exhibiting a growth rate (CAGR) of 3.52% during 2025-2033. The market is driven by the widespread adoption of minimally invasive surgeries (MIS), the growing geriatric population, the growing access to healthcare services on account of inflating income levels, and the increasing incidence of spinal disorders.
Increasing Prevalence of Spinal Disorders
The growing occurrence of spinal disorders is affecting the spine biologics market growth. In addition, the increasing life expectancy, and lifestyle issues, are spurring the development of degenerative illnesses such as disc disease and spinal stenosis. According to the World Health Organization (WHO) in 2020 approximately 1 in 13 individuals equating to 619 million individuals experienced low back pain (LBP), a 60% increase from 1990. It is further estimated that low back pain cases will increase by around 843 million by 2050 which emphasizes the widespread nature of spinal issues. The rising number of incidences is with the age group of 80 years, and the increasing number of LBP cases occur at the age of 50-55 years. This widespread prevalence necessitates ongoing development and deployment of effective treatments, including biologics, which help promote bone growth and healing, making them critical in treating these pervasive conditions.
Rising Adoption of Minimally Invasive Surgeries (MIS)
Minimally invasive surgeries (MIS) for spinal conditions are preferred due to their less distressful nature and quicker recovery times compared to traditional open surgeries. The global market for minimally invasive surgery is projected to expand at a compound annual growth rate (CAGR) of roughly 6% during 2024-2032 as per the IMARC GROUP. It reached US$ 52.9 Billion in 2023 and anticipates the market to reach US$ 91.0 Billion by 2032. This growth is declarative of a shift in surgical methods that reduce hospital stays and recovery periods, which is particularly beneficial for spine biologics market value.
Growing Geriatric Population
The growing geriatric population is driving the spine biologics market demand. As individuals age, the risk of developing spinal disorders increases, necessitating more frequent and intensive care. As per the data from the UNITED NATIONS population aged 65 and over is expected to rise from 10% in 2022 to 16% in 2050. It is forecasted that individuals aged 65 years or above globally will double the number of children under age 5 and will be equal to the number of 12-year-old children. It means a rising number of age-associated spinal conditions, escalating the demand for treatments that are effective and minimally invasive. For instance, biologics, which aid in the natural healing processes, are particularly suited to meet these needs, aligning with the growing healthcare requirements of an aging global population.
Bone graft substitutes account for the majority of the market share
Bone graft substitutes offer an alternative to customary bone grafts, stipulating structural support and facilitating bone healing processes in spinal surgeries. These substitutes embrace synthetic materials, allografts, and demineralized bone matrix, and are advocated for their aptitude to endorse bone fusion and curb the need for harvesting bone from the patient's own body, minimizing surgical complications and recovery time. As per the statistics by IMARC GROUP, the global bone graft and substitute market reached US$3.2 Billion in 2023. It is estimated to reach US$ 5.1 Billion by 2032 with a compound annual growth rate (CAGR) of 5.2% during 2024-2032. Moreover, various advancements in biomaterials, regenerative medicine, and bone graft substitutes are witnessing increasing adoption in spinal procedures, thus positively increasing the spine biologic market value.
Minimally invasive spine surgery holds the largest share of the industry
Minimally invasive spine surgery is primarily attributed to the growing preference for minimally invasive procedures among patients and healthcare providers. Minimally invasive spine surgery offers several advantages over traditional open surgeries, including smaller incisions, reduced blood loss, shorter hospital stays, and faster recovery times. As a result, it has gained popularity for treating various spinal conditions, such as degenerative disc disease, herniated discs, spinal stenosis, and vertebral fractures. According to the NATIONAL LIBRARY OF MEDICINE, minimally invasive spine (MIS) surgery has advanced significantly with imaging navigation systems, robotics, and endoscopy. More than 400,000 cases are accomplished in the United States annually with spine fusion being the commonly conducted and established treatment options for spine trauma, tumors, structural deformities, and degenerative disorders.
Hospitals represent the leading market segment
Hospitals are major centers for specialized medical care that attract a considerable proportion of patients seeking treatments for several forms of spinal disorders including those that necessitate surgeries. Furthermore, some hospitals have dedicated spine centers or departments where they offer services, making them the preferred centers for comprehensive source care. Besides this, hospitals have strong collaborations with spine biologic manufacturers and suppliers, thereby enhancing the efficiency of the equipment. In June 2022, Xenco Medical broadened its range of devices for ambulatory surgery centers by securing Food and Drug Administration (FDA) clearance and introducing its Multilevel CerviKit for their single use. It comprises a complete suite of implants and single-use instruments for two, three, and four level procedures of the anterior cervical spine.
North America leads the market, accounting for the largest spine biologics market share
The report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, North America represents the largest regional market for spine biologics.
North America's dominance in the market can be attributed to highly developed healthcare infrastructure, the high rate of innovative medical technologies' adoption, and a large patient pool with spinal disorders. For instance, as per the data from the National Spinal Cord Injury Association, approximately 450,000 individuals reside in the United States with a spinal cord injury (SCI). Annually, an estimated 17,000 new cases of SCI arise in the U.S., predominantly stemming from trauma to the vertebral column. Thus, the increasing incidence of SCI population is significantly escalating the demand for spine biologics to treat disorders across the region. Additionally, favorable reimbursement policies, strong R&D efforts, and awareness of the advantages of minimally invasive surgical procedures are generating the spine biologics market revenue in North America.