![]() |
市场调查报告书
商品编码
1820450
吸入式一氧化氮市场规模、份额、趋势及各应用及地区预测(2025-2033)Inhaled Nitric Oxide Market Size, Share, Trends and Forecast by Application and Region, 2025-2033 |
||||||
2024 年,全球吸入式一氧化氮市场规模为 10.0283 亿美元。展望未来, IMARC Group估计,到 2033 年,市场规模将达到 17.3293 亿美元,2025 年至 2033 年的复合年增长率为 5.64%。目前,北美占据市场主导地位,2024 年的市占率将超过 77.7%。吸入式一氧化氮的市场份额正在扩大,这得益于越来越多的临床指南支持在新生儿加护病房 (NICU) 中广泛使用吸入式一氧化氮,以及对医疗技术的投资不断增加,以改善治疗方法,从而改善患者的治疗效果。
新生儿併发症病例的增加推动了市场的成长。医院和医疗保健机构将吸入式一氧化氮作为新生儿缺氧性呼吸衰竭和急性呼吸窘迫症候群 (ARDS) 患者的关键治疗方法。慢性阻塞性肺病 (COPD) 和其他肺部疾病发生率的上升进一步刺激了对吸入式一氧化氮的需求。此外,药物输送系统的进步提高了吸入式一氧化氮治疗的效率和可及性。此外,医疗基础设施和研究方面不断增长的投资也鼓励了创新,拓展了其医疗应用。监管部门的批准和有利的医疗政策支持其更广泛的应用,尤其是在已开发地区。
由于多种因素,美国已成为吸入型一氧化氮市场的主要地区。呼吸系统疾病、新生儿併发症和肺动脉高压的日益普及为吸入型一氧化氮市场提供了良好的前景。根据美国政府官方网站公布的资料,截至 2025 年 2 月,6.5% 的美国人患有呼吸道合胞病毒 (RSV)。本院依靠吸入型一氧化氮治疗患有缺氧呼吸衰竭的新生儿和急性呼吸窘迫症候群 (ARDS) 患者。先进的医疗基础设施和对医学研发 (R&D) 活动的大力投资促进了创新,改善了药物输送系统并扩大了治疗应用。此外,大型製药公司的存在加速了产品的开发和可用性。随着老龄人口的成长和群众对呼吸照护意识的提高,美国各医疗机构对吸入型一氧化氮的需求持续增强。
新生儿呼吸系统疾病盛行率不断上升
新生儿呼吸道及其他后续疾病的发生率不断上升,推动了市场的成长。许多早产儿患有缺氧性呼吸衰竭和持续性肺动脉高压,而吸入一氧化氮有助于提高氧气含量,减少对体外膜氧合 (ECMO) 等侵入性手术的需求。根据美国国立卫生研究院的数据,全球五岁以下儿童下呼吸道感染病例达 3,780 万例,死亡人数达 501,910 人,伤残调整生命年达 4,480 万年。随着全球早产儿的增加,医院和新生儿监护室越来越依赖这种疗法来减少併发症。监管部门的批准和临床指南进一步支持了其在新生儿加护病房的广泛使用。此外,正在进行的研发工作正在帮助探索吸入一氧化氮在治疗其他新生儿疾病方面的新应用,从而提高其应用率。随着医疗保健投入的增加和新生儿护理的加强,对吸入一氧化氮的需求正在上升,使其成为治疗新生儿呼吸系统疾病的重要方法。
老年人口不断增加
老年人口的成长对市场产生了正面影响。老年人更容易患高血压、动脉粥状硬化、週边动脉疾病、心臟衰竭和血栓形成,所有这些疾病都需要吸入一氧化氮来扩张血管。根据 2024 年 MDPI 报告,心臟衰竭盛行率随着年龄增长而上升,每年影响约 1% 的 55 岁以下人群,超过 10% 的 70 岁以上人群。老年人口也相对更容易罹患慢性阻塞性肺病 (COPD)、肺动脉高压和急性呼吸窘迫症候群 (ARDS) 等疾病,因此需要有效的氧气治疗。吸入一氧化氮有助于改善氧气流量并降低肺压,使其成为老年患者的关键治疗方法。随着预期寿命的延长,医疗保健系统更加重视先进的呼吸治疗,导致医院和长期照护机构更多地采用吸入一氧化氮。随着需要呼吸支持的老年人数量不断增加,对吸入一氧化氮的需求也上升。
增加对先进医疗基础设施的投资
对先进医疗基础设施的投资不断增加,推动了吸入式一氧化氮市场的成长。根据国际贸易管理局 (ITA) 官方网站提供的信息,印度政府将于 2024 年在全国范围内启动五个新的全印度医学科学院 (AIIMS) 中心,并推出共 202 项医疗基础设施计划,以促进医疗技术的进步。设备齐全的医院、专门的新生儿护理单位和现代化的重症监护设施广泛使用吸入式一氧化氮治疗缺氧呼吸衰竭、肺动脉高压和急性呼吸窘迫症候群 (ARDS) 等疾病。先进医疗设备的普及提高了吸入式一氧化氮疗法的效率,使其对患有呼吸系统疾病的新生儿和成年人更有效。对医疗技术和研发活动的大力投资进一步增强了治疗方法,从而改善了患者的治疗效果。监管机构也支持创新,鼓励开发改良的吸入装置和药物输送系统。
The global inhaled nitric oxide market size was valued at USD 1,002.83 Million in 2024. Looking forward, IMARC Group estimates the market to reach USD 1,732.93 Million by 2033, exhibiting a CAGR of 5.64% from 2025-2033. North America currently dominates the market, holding a market share of over 77.7% in 2024. The inhaled nitric oxide market share is expanding, driven by the rising adoption of clinical guidelines that support the widespread utilization of inhaled nitric oxide in neonatal intensive care units (NICUs), along with increasing investments in healthcare technology to enhance treatment methods, leading to better patient outcomes.
The increasing cases of neonatal complications are fueling the market growth. Hospitals and healthcare providers use inhaled nitric oxide as a critical treatment for newborns with hypoxic respiratory failure and patients suffering from acute respiratory distress syndrome (ARDS). The rising incidence of chronic obstructive pulmonary disease (COPD) and other lung disorders is further catalyzing the demand for inhaled nitric oxide. Besides this, advancements in drug delivery systems improve the efficiency and accessibility of inhaled nitric oxide therapy. Moreover, the growing investments in healthcare infrastructure and research are encouraging innovations, expanding its medical applications. Regulatory approvals and favorable healthcare policies support wider adoption, especially in developed regions.
The United States has emerged as a major region in the inhaled nitric oxide market owing to many factors. The increasing prevalence of respiratory diseases, neonatal complications, and pulmonary hypertension is offering a favorable inhaled nitric oxide market outlook. According to the data published on the official website of the United States government, as of February 2025, 6.5% of people in the US were suffering from respiratory syncytial virus (RSV). Hospitals rely on inhaled nitric oxide to treat newborns with hypoxic respiratory failure and patients with ARDS. Advanced healthcare infrastructure and strong investments in medical research and development (R&D) activities promote innovations, improving drug delivery systems and expanding therapeutic applications. Additionally, the presence of major pharmaceutical companies accelerates product development and availability. With a growing elderly population and rising awareness among the masses about respiratory care, the demand for inhaled nitric oxide in the US continues to strengthen across various healthcare settings.
Growing prevalence of respiratory diseases in newborns
The increasing prevalence of respiratory and other subsequent diseases in newborns is propelling the market growth. Many premature babies suffer from hypoxic respiratory failure and persistent pulmonary hypertension, conditions where inhaled nitric oxide helps to improve oxygen levels and reduce the need for invasive procedures like extracorporeal membrane oxygenation (ECMO). According to the NIH, lower respiratory infections in children under five accounted for 37.8 Million cases, 501,910 deaths, and 44.8 Million disability-adjusted life years worldwide. As preterm births rise globally, hospitals and neonatal care units rely more on this therapy to reduce complications. Regulatory approvals and clinical guidelines further support its widespread use in NICUs. Additionally, ongoing R&D efforts are assisting in exploring new applications for inhaled nitric oxide in treating other neonatal conditions, increasing its adoption. With high healthcare investments and enhanced neonatal care, the demand for inhaled nitric oxide is rising, making it a crucial treatment for newborn respiratory disorders.
Rising geriatric population
The growing geriatric population is positively influencing the market. Older adults are more susceptible to hypertension, atherosclerosis, peripheral artery disease, heart failure, and thrombosis, all of which require inhaled nitric oxide for vasodilation. As per a 2024 MDPI report, heart failure prevalence rose with age, annually affecting about 1% of individuals under 55 and exceeding 10% in those over 70. The elderly population is also relatively more prone to conditions like COPD, pulmonary hypertension, and ARDS, creating the need for effective oxygen therapy. Inhaled nitric oxide helps to improve oxygen flow and reduce lung pressure, making it a crucial treatment for elderly patients. As life expectancy rises, healthcare systems focus on advanced respiratory treatments, leading to higher adoption of inhaled nitric oxide in hospitals and long-term care facilities. With the increasing number of elderly individuals requiring respiratory support, the demand for inhaled nitric oxide is rising.
Increasing investments in advanced healthcare infrastructure
The rising investments in advanced healthcare infrastructure are fueling the inhaled nitric oxide market growth. According to the information provided on the official website of the International Trade Administration (ITA), in 2024, the Indian Government launched five new All India Institute of Medical Sciences (AIIMS) centers and introduced a total of 202 healthcare infrastructure initiatives throughout the country to promote progress in healthcare technologies. Well-equipped hospitals, specialized neonatal care units, and modern intensive care facilities widely employ inhaled nitric oxide for treating conditions like hypoxic respiratory failure, pulmonary hypertension, and ARDS. The availability of advanced medical equipment improves the efficiency of inhaled nitric oxide therapy, making it more effective for both newborns and adults with respiratory disorders. Strong investments in healthcare technology and R&D activities further enhance treatment methods, leading to better patient outcomes. Regulatory bodies also support innovations, encouraging the development of improved inhalation devices and drug delivery systems.
Neonatal respiratory treatment held 86.1% of the market share in 2024. It is the primary therapy for newborns with hypoxic respiratory failure and persistent pulmonary hypertension. Inhaled nitric oxide helps to improve oxygen levels by relaxing blood vessels in the lungs, reducing the need for invasive procedures like ECMO. Hospitals widely adopt this treatment due to its effectiveness and safety in managing neonatal respiratory distress. The increasing number of preterm births and rising cases of neonatal lung disorders further drive the demand for inhaled nitric oxide. Regulatory approvals and clinical guidelines support the employment of inhaled nitric oxide in neonatal care, ensuring its availability in healthcare settings. Additionally, ongoing research focuses on expanding its applications in premature infants, increasing its market dominance. With advancements in neonatal care and better access to specialized treatments, the requirement for inhaled nitric oxide in neonatal respiratory therapy is growing, keeping it at the forefront of the market.
North America, accounting for 77.7%, enjoys the leading position in the market. The region is noted for its strong healthcare infrastructure, high prevalence of respiratory diseases, and increasing neonatal complications. The region has a well-developed hospital network that widely adopts inhaled nitric oxide therapy for conditions like hypoxic respiratory failure in newborns and ARDS in adults. The rising cases of COPD and pulmonary hypertension further drive the demand for inhaled nitric oxide. As per the information provided on the official website of the National Library of Medicine, as of April 2024, a sum of 29,445 male and 14,693 female cases of COPD were registered in workers in Canada. The ongoing R&D efforts by pharmaceutical companies contribute to continuous innovations in drug delivery systems and treatment protocols. Favorable regulatory policies and approvals from government agencies are supporting the market growth by ensuring safety. Additionally, high healthcare spending and reimbursement policies make inhaled nitric oxide treatments more available to patients.
United States Inhaled Nitric Oxide Market Analysis
The United States holds 93.20% of the market share in North America. The market in the United States is significantly driven by the increasing incidence of neonatal hypoxic respiratory failure, pulmonary hypertension (PAH), and ARDS. The Pulmonary Hypertension Association Registry anticipated that in 2022, the mortality rates for patients with PAH at 1, 2, and 3 years were 8%, 16%, and 21%, respectively, in the US. In 2011, the estimated prevalence of PAH was 109 per Million in commercially insured individuals and 451 per Million in Medicare patients, whereas in 2022, projections suggested approximately 40,000 adult PAH patients in the country. The high adoption of inhaled nitric oxide therapy in NICUs and post-cardiac surgery patients is driving the demand. The market is witnessing significant innovations, with companies developing advanced inhaled nitric oxide delivery systems that eliminate bulky gas cylinders, improving hospital efficiency and patient care. Regulatory approvals for portable and home-use inhaled nitric oxide devices are expanding accessibility beyond hospital settings. Increased competition is accelerating advancements in cost-effective and safer inhaled nitric oxide therapies. Moreover, the rising focus on digital health integration and precision dosing is supporting the market growth.
Europe Inhaled Nitric Oxide Market Analysis
The European market is expanding due to the strong healthcare infrastructure, rising cases of chronic lung diseases, and increasing preterm births requiring respiratory support. According to the European Environment Agency, in 2021, respiratory diseases were the third leading cause of death in its member countries, accounting for approximately 420,000 fatalities annually, with over 60% due to chronic respiratory diseases (CRDs). Environmental factors contributed to one-third of these deaths, nearly 80,000 preventable fatalities each year. Air pollution (14%), extreme temperatures (11%), occupational exposures (8%), and second-hand smoke (3%) were major risk causes. Regulatory frameworks, including CE Mark approvals, ensure high standards for inhaled nitric oxide therapy, promoting its use in hospitals and specialized clinics. Research into inhaled nitric oxide's role in treating PAH and post-operative care is driving the demand. Increased investments in precision medicine and artificial intelligence (AI)-based monitoring systems are improving therapy efficiency. Collaborations between healthcare institutions and pharmaceutical companies are leading to innovations.
Asia-Pacific Inhaled Nitric Oxide Market Analysis
The Asia-Pacific market is seeing a rapid rise attributed to increasing healthcare investments, rising neonatal respiratory disorders, and the growing awareness about advanced respiratory treatments. According to the India Brand Equity Foundation, India's healthcare sector was valued at USD 372 Billion in 2024, employing 7.5 Million people. Public healthcare spending reached 1.9% of GDP in FY24, while the hospital market, worth USD 98.98 Billion in 2023, is set to attain USD 193.59 Billion by 2032. China, Japan, and India are leading in inhaled nitric oxide adoption, driven by government initiatives to improve neonatal and pulmonary care. The expansion of tertiary hospitals and research centers is catalyzing the demand for advanced inhaled nitric oxide delivery systems. Industry leaders are investing in localized production and cost-effective solutions to refine market penetration.
Latin America Inhaled Nitric Oxide Market Analysis
In Latin America, the market is experiencing growth on account of the improved healthcare infrastructure, neonatal care awareness, and rising respiratory illness cases. An NIH review of 3,627 ARDS patients in 32 studies found 52% mortality rate in Latin America in 2023, varying by study type and region. Brazil and Mexico lead inhaled nitric oxide adoption through government pediatric and critical care initiatives. Investments in cost-effective respiratory therapies are enhancing local production and distribution. Portable inhaled nitric oxide delivery systems are expanding access in remote areas. Moreover, private-sector investments and worldwide collaborations are improving inhaled nitric oxide availability. Research into inhaled nitric oxide for respiratory infections and pulmonary conditions is further creating new market opportunities across Latin America.
Middle East and Africa Inhaled Nitric Oxide Market Analysis
The market in the Middle East and Africa is experiencing growth driven by rising investments in neonatal and critical care, particularly in GCC countries. Increasing respiratory diseases, premature births, and ARDS cases are driving hospital demand for inhaled nitric oxide therapy. During Q1 2024, the Dubai Health Authority (DHA) reported a 9% increase in healthcare settings and a 7% rise in professionals, licensing 12,319 specialists and 150 centers, totaling 5,020 facilities and 59,509 healthcare workers. Partnerships with international healthcare providers are promoting inhaled nitric oxide technology adoption.
Key players work on developing efficient solutions to meet the high inhaled nitric oxide market demand. They are investing in R&D activities to improve drug delivery systems and expand the medical applications of inhaled nitric oxide. They focus on creating modern inhalation devices that enhance treatment efficiency and patient outcomes. Strategic partnerships with healthcare providers and research institutions help to strengthen distribution networks and accelerate innovations. Regulatory approvals and compliance with safety standards ensure widespread adoption in hospitals and clinics. Key companies also wager on clinical trials to explore new therapeutic uses, increasing market potential. Marketing efforts and awareness campaigns educate healthcare professionals on the benefits of inhaled nitric oxide therapy, driving the demand. Additionally, broadening production capabilities and improving supply chain efficiency are making treatments more accessible. For instance, in February 2024, Third Pole Therapeutics reported the successful conclusion of a preliminary feasibility study for eNOfit, a portable delivery system for inhaled nitric oxide aimed at treating pulmonary hypertension linked to interstitial lung disease. The two-pound appliance enabled use at home and while on the go. This achievement promoted clinical trials and activated the final financing of Third Pole's USD 32 Million Series B funding round.