市场调查报告书
商品编码
1470778
製备色谱和过程层析法市场:按产品类型和最终用户 - 2024-2030 年全球预测Preparative & Process Chromatography Market by Product, Type (Gas Chromatography, Gel-permeation Chromatography, Hydrophobic Interaction Chromatography), End-User - Global Forecast 2024-2030 |
※ 本网页内容可能与最新版本有所差异。详细情况请与我们联繫。
预计2023年製备色谱和製层析法市场规模为102亿美元,预计2024年将达114.9亿美元,2030年将达237亿美元,复合年增长率为12.80%。
层析法和製程层析法是用于以适合商业生产的规模分离和精製化合物的先进技术。製备层析法是指从混合物中分离出足够量的特定化合物以供后续使用或分析的过程,通常用于实验室或研究环境。另一方面,过程层析法是製备层析法的放大版本,旨在处理大规模分离和精製。过程层析法在製造业中发挥着至关重要的作用,在製造业中,一致的品质、效率和法律规章遵循至关重要。层析法和製程层析法是广泛用于药品、生物技术产品和特种化学品生产中化学和生化化合物分离和精製的基本技术。由于生物製药需求不断增长、确保产品纯度的严格法规、层析法技术的进步以及生物技术和製药领域的大量研发投资,製备和工艺层析法市场正在快速成长。然而,他们也面临着挑战,例如与先进层析法系统相关的高成本、需要熟练的操作员来管理复杂的流程以及来自其他分离技术的竞争。对客製化服务和创新的一次性层析法解决方案的需求不断增长,为未来的市场成长提供了利润丰厚的机会。
主要市场统计 | |
---|---|
基准年[2023] | 102亿美元 |
预测年份 [2024] | 114.9亿美元 |
预测年份 [2030] | 237亿美元 |
复合年增长率(%) | 12.80% |
在产品药物发现中扩大製备层析法的采用
製备层析法用于从复杂的混合物中精製和分离特定的化合物。製备层析法的主要应用是研究和开发、大规模製造和纯物质的生产,特别是在製药和生物技术领域。该方法在药物发现、活性药物成分 (API) 的小规模合成和新型化合物开发的学术环境中至关重要。製程层析法广泛用于大规模製造过程中生物分子的连续精製,特别是在生物製药产业。该技术可生产大量生物分子,如疫苗、单株抗体和治疗性蛋白质。这是良好生产规范 (GMP) 环境的重要组成部分。层析法和製程层析法之间的选择主要取决于操作规模、监管需求和纯度规格。製备层析法系统必须具有高度适应性,才能实现方法开发和放大製程。製层析法系统专为坚固耐用、高通量、可自动整合到生产线中而设计,并专注于 GMP 合规性。
类型 製药业对 HPLC 纯度检测和产品品管的需求增加
气相层析法是分析化学中广泛使用的方法,用于分离和分析蒸发而不分解的化合物。凝胶渗透层析法,也称为尺寸排阻层析法,主要用于大分子和聚合物的分析。其效用基于按分子大小分离分析物。疏水交互作用层析法是蛋白质和复杂生物样品的首选方法。它的优势在于能够在分离过程中维持生物分子的活性和构形。该技术在生物技术和製药领域受到青睐,尤其是抗体精製。液相层析法是一种多功能分析技术,具有从药物到环境分析的多种应用。亲和层析法是一种基于固定配体与目标分子的特异性相互作用的选择性精製技术。急速层析法也称为中压层析法,是製备型液相层析法的一种快速型态。透过在正压下使化合物通过填充固定相(例如硅胶或氧化铝)的管柱,将化合物从混合物中分离和精製。高效液相层析(HPLC) 是液相层析法的一种高级型态,它使用高压迫使样品通过填充固定相微粒的管柱。以高分辨率分离复杂的混合物并处理各种样品类型。离子交换层析法技术依赖于样品中的带电粒子与固定相上附着的带相反电荷的基团之间的可逆相互作用。尺寸排阻层析法(SEC) 或凝胶过滤层析法可根据分子通过填充多孔珠的管柱时的大小和形状来分离分子。高效液相层析(HPLC) 是一种常见的层析法,以其高灵敏度和特异性而闻名。纸层析法是一种具有成本效益的教育技术,主要用于教授层析法原理和简单的分离。与更先进的方法相比,低解析度和效率限制了其应用。薄层层析法也是一种简单、快速、有效的定性技术。它通常用于有机化学和生物化学中监测反应进程和分析混合物的组成。
最终用户:经常使用层析法和製程层析法来进行製程优化和製造品管
在学术实验室中,製备层析法和过程层析法主要用于教育目的和基础研究。这些实验室需要强大且多功能的系统来进行各种实验和教育演示。成本效益和易用性非常重要,因为资金有限且需要专门培训。生物技术和製药公司在药物发现、开发和大规模生产中广泛使用层析法和工艺层析法。效率、可重复性、遵守监管标准以及扩大商业生产的能力至关重要。食品和营养补充食品依靠层析法和工艺层析法来提取和精製营养补充、食品食品和天然化合物。为了确保商业性可行性,系统需要能够处理具有不同纯度要求的各种天然产物,并且通常具有高通量。
区域洞察
在製药和生物技术产业(主要在美国)扩张的推动下,美洲的製备和製程层析法市场呈现稳定成长。该地区成熟的製药公司和强大的研发活动促进了对层析法技术不断增长的需求。此外,FDA 等监管机构对医药品认证过程製定了严格的指导方针,推动了层析法系统的采用,以确保整个美洲的合规性。欧洲、中东和非洲地区的层析法层析法不断发展。政府对製药和生物技术研究的资助也支持了该地区层析法市场的成长。由于中国和印度製药和生物技术行业的快速扩张,亚太地区是成长最快的製备和工艺层析法市场。製造成本的下降以及政府对医疗保健和药品研发的投资增加是该地区的主要市场驱动力。学名药产量的增加和委外研发机构(CRO) 数量的快速增加也促进了亚太地区製备和製程层析法市场的成长。
FPNV定位矩阵
FPNV 定位矩阵对于评估製备和製程层析法市场至关重要。我们检视与业务策略和产品满意度相关的关键指标,以对供应商进行全面评估。这种深入的分析使用户能够根据自己的要求做出明智的决策。根据评估,供应商被分为四个成功程度不同的像限:前沿(F)、探路者(P)、利基(N)和重要(V)。
市场占有率分析
市场占有率分析是一种综合工具,可以对製备色谱和工艺层析法市场中供应商的现状进行深入而深入的研究。全面比较和分析供应商在整体收益、基本客群和其他关键指标方面的贡献,以便更好地了解公司的绩效及其在争夺市场占有率时面临的挑战。此外,该分析还提供了对该行业竞争特征的宝贵见解,包括在研究基准年观察到的累积、分散主导地位和合併特征等因素。这种详细程度的提高使供应商能够做出更明智的决策并制定有效的策略,从而在市场上获得竞争优势。
1. 市场渗透率:提供有关主要企业所服务的市场的全面资讯。
2. 市场开拓:我们深入研究利润丰厚的新兴市场,并分析其在成熟细分市场的渗透率。
3. 市场多元化:提供有关新产品发布、开拓地区、最新发展和投资的详细资讯。
4.竞争评估与资讯:对主要企业的市场占有率、策略、产品、认证、监管状况、专利状况、製造能力等进行全面评估。
5. 产品开发与创新:提供对未来技术、研发活动和突破性产品开发的见解。
1.製备/製程层析法市场的市场规模和预测是多少?
2.在製备层析和製程层析法市场的预测期内,有哪些产品、细分市场、应用和领域需要考虑投资?
3.製备/製层析法市场的技术趋势和法规结构是什么?
4.製备/製层析法市场主要供应商的市场占有率是多少?
5.进入製备/製层析法市场的适当型态或策略手段是什么?
[185 Pages Report] The Preparative & Process Chromatography Market size was estimated at USD 10.20 billion in 2023 and expected to reach USD 11.49 billion in 2024, at a CAGR 12.80% to reach USD 23.70 billion by 2030.
Preparative and process chromatography are advanced techniques used to separate and purify chemical compounds on a scale suitable for commercial production. Preparative chromatography refers to the process of isolating specific compounds from mixtures in sufficient quantities for further use or analysis, typically in a laboratory or research setting. Process chromatography, on the other hand, is an upscaled version of preparative chromatography designed to handle large-scale separations and purifications, often within industrial environments. It plays a crucial role in the manufacturing sector, where consistent quality, efficiency, and regulatory compliance are paramount. Preparative and process chromatography is an essential technique widely used to separate and purify chemical and biochemical compounds for the production of pharmaceuticals, biotech products, and specialty chemicals. The preparative and process chromatography market is growing rapidly, driven by increasing demands for biopharmaceuticals, stringent regulations ensuring product purity, advancements in chromatographic technologies, and significant R&D investments in the biotech and pharma sectors. However, the market also confronts challenges such as the steep costs associated with advanced chromatographic systems, the need for skilled operators to manage the complexity of the processes, and competition from other separation techniques. Growing demand for tailored services and innovative single-use chromatography solutions has been presenting lucrative opportunities for future market growth.
KEY MARKET STATISTICS | |
---|---|
Base Year [2023] | USD 10.20 billion |
Estimated Year [2024] | USD 11.49 billion |
Forecast Year [2030] | USD 23.70 billion |
CAGR (%) | 12.80% |
Product: Growing adoption of preparative chromatography for drug discovery
Preparative chromatography is leveraged to purify and isolate specific compounds from complex mixtures. Its primary application is in producing pure substances for research, development, and large-scale manufacturing, especially in the pharmaceutical and biotechnology sectors. This method is crucial in drug discovery, small-scale synthesis for active pharmaceutical ingredients (APIs), and academic settings for novel compound development. Process Chromatography is extensively used in the continual purification of biological molecules during large-scale manufacturing processes, particularly in the biopharmaceutical industry. This technique produces high volumes of biomolecules such as vaccines, monoclonal antibodies, and therapeutic proteins. It is a critical component of the good manufacturing practice (GMP) environments. The choice between preparative and process chromatography depends primarily on the scale of operation, regulatory necessities, and purity specifications. Preparative chromatography systems must be highly adaptable, allowing for method development and scale-up processes. Process chromatography systems are designed for robustness, high throughput, and integration into automatable production lines, focusing on GMP compliance.
Type: Increasing demand for HPLC in the pharmaceutical industry for purity testing and quality control of products
Gas chromatography is a prevalent method utilized in analytical chemistry for isolating and analyzing compounds that can be vaporized without decomposition. Gel-permeation chromatography, also known as size-exclusion chromatography, serves primarily for the analysis of macromolecules and polymers. Its utility is based on the separation of analytes by molecular size. Hydrophobic interaction chromatography is a method of choice for proteins and complex biological samples. Its strength lies in its capacity to maintain the activity and conformation of biomolecules during separation. This technique is favored in the biotechnological and pharmaceutical sectors, particularly for antibody purification. Liquid chromatography is a versatile analytical technique with many applications, from pharmaceutical to environmental analysis. Affinity chromatography is a selective technique used for purification based on the specific interaction between an immobilized ligand and its target molecule. Flash chromatography, also known as medium-pressure chromatography, is a rapid form of preparative liquid chromatography. It separates and purifies compounds from a mixture by passing them via a column packed with a stationary phase, typically silica gel or alumina, under positive pressure. High-performance liquid chromatography (HPLC) is an advanced form of liquid chromatography that uses high pressure to drive the sample through a column packed with fine particles of the stationary phase. It provides high-resolution separations of complex mixtures and is capable of handling a variety of sample types. Ion-exchange chromatography This technique relies on the reversible interaction between charged particles in a sample and oppositely charged groups attached to the stationary phase. Size-exclusion chromatography (SEC), or gel filtration chromatography, separates molecules based on size and shape as they pass through a column filled with porous beads. High-performance liquid chromatography (HPLC) is a popular variant known for its high sensitivity and specificity. Paper chromatography is an educational and cost-effective technique primarily used to teach chromatography principles and simple separations. Its applications are limited compared to more advanced methods due to lower resolution and efficiency. Thin-layer chromatography is another simple, quick, and effective qualitative technique. It is commonly used in organic chemistry and biochemistry to monitor the progress of reactions and analyze mixtures' composition.
End-User: Significant use of preparative and process chromatography for process optimization and production quality control
Academic research laboratories primarily use preparative and process chromatography for educational purposes and basic research. These laboratories require robust and versatile systems for various experiments and educational demonstrations. Cost-effectiveness and ease of use are often crucial, as funding can be limited, and users may need specialized training. Biotechnology & pharmaceutical companies extensively use preparative and process chromatography in drug discovery, development, and large-scale production. Efficiency, reproducibility, compliance with regulatory standards, and the ability to scale up for commercial production are essential. Food and nutraceutical companies utilize preparative and process chromatography to extract and purify nutraceuticals, food additives, and natural compounds. They require systems that can handle various natural products with varying purity requirements, often at high throughput, to ensure commercial viability.
Regional Insights
The preparative and process chromatography market in the Americas has shown a robust growth rate driven by the expanding pharmaceutical and biotechnology industries, especially in the United States. The presence of established pharmaceutical companies and a strong focus on R&D activities contribute to the higher demand for chromatography techniques in the region. Moreover, regulatory bodies, including the FDA have stringent guidelines for drug approval processes, which in turn boosts the adoption of chromatography systems to ensure compliance across the Americas. The EMEA region presents a growing market landscape for preparative and process chromatography, supported by the presence of a well-established pharmaceutical industry, a strong focus on quality control, and high standards for drug development. Government funding for pharmaceutical and biotechnological research also supports the growth of the chromatography market in the region. The Asia-Pacific region is witnessing the fastest growth in the preparative and process chromatography market, attributed to the rapid expansion of pharmaceutical and biotech industries in China and India. Lower manufacturing costs and increasing government investments in healthcare and pharmaceutical R&D are significant market drivers in the region. Increased generic drug production and a surge in the number of Contract Research Organizations (CROs) also contribute to the growth of the preparative and process chromatography market in the APAC.
FPNV Positioning Matrix
The FPNV Positioning Matrix is pivotal in evaluating the Preparative & Process Chromatography Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).
Market Share Analysis
The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the Preparative & Process Chromatography Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.
Key Company Profiles
The report delves into recent significant developments in the Preparative & Process Chromatography Market, highlighting leading vendors and their innovative profiles. These include Agilent Technologies, Inc, Akzo Nobel N.V., Altmann Analytik GmbH & Co. Kg, Bio-Rad Laboratories, Inc., Biobase Biodusty(Shandong), Co., Ltd., Bruker Corporation, Centurion Scientific, Daicel Corporation, Danaher Corporation, General Electric Company, Gilson, Inc., GL Sciences Inc., Hamilton Bonaduz AG, Hitachi High-Technologies Corporation, JASCO Corporation, Merck KGaA, Perkinelmer, Inc., Repligen Corporation, Restek Corporation, Sartorius AG, Sykam GmbH, Thermo Fisher Scientific Inc., Unimicro Technologies, Waters Corporation, and Welch Materials, Inc..
Market Segmentation & Coverage
1. Market Penetration: It presents comprehensive information on the market provided by key players.
2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.
3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.
4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.
5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.
1. What is the market size and forecast of the Preparative & Process Chromatography Market?
2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the Preparative & Process Chromatography Market?
3. What are the technology trends and regulatory frameworks in the Preparative & Process Chromatography Market?
4. What is the market share of the leading vendors in the Preparative & Process Chromatography Market?
5. Which modes and strategic moves are suitable for entering the Preparative & Process Chromatography Market?