市场调查报告书
商品编码
1464888
去矿骨基质市场:按产品、型态、应用和最终用途 - 2024-2030 年全球预测Demineralized Bone Matrix Market by Product (Gel, Putty, Putty Combined with Cancellous Chips), Administration Mode (Implantation, Injection), Application, End-Use - Global Forecast 2024-2030 |
※ 本网页内容可能与最新版本有所差异。详细情况请与我们联繫。
脱矿骨基质市场规模预计到2023年为6.7114亿美元,2024年达到7.1336亿美元,预计到2030年将达到10.4637亿美元,复合年增长率为6.54%。
去矿骨基质(DBM)是一种骨移植物,源自同种异体骨的胶原蛋白基质,经由酸萃取过程脱矿。这种脱矿过程暴露了骨生长因子,尤其是骨生成激素(BMP),使 DBM 具有骨诱导性并能够促进新骨形成。 DBM 的使用不断增长的主要因素包括其在骨骼修復和再生方面的有效性,其在各种整形外科、牙科和脊柱手术中作为移植物延长剂的作用,其减少自体移植物需求的潜力,从而包括最大限度地减少供体部位发病率。然而,DBM製剂之间骨诱导能力的差异、免疫抗原性反应的可能性以及某些DBM製剂的高成本对DBM製剂的采用提出了重大挑战。为了解决这些限制,正在进行的研究和技术进步集中在提高 DBM 配方的一致性和骨诱导潜力。该策略包括开发将DBM与合成或天然生物材料结合的复合植入物,以改善结构和功能特性,以及先进的加工以在确保安全的同时保持生物活性。扩大新兴地区的应用以及与下一代生技药品的整合代表了 DBM 的动态成长路径,并为研发和临床应用打开了新的大门。
主要市场统计 | |
---|---|
基准年[2023] | 67114万美元 |
预测年份 [2024] | 71336万美元 |
预测年份 [2030] | 10.4637 亿美元 |
复合年增长率(%) | 6.54% |
腻子与 DBM 产品的鬆质碎片的结合使用可以实现广泛的骨骼修復。
DBM 凝胶是一种流动製剂,可轻鬆应用于需要精确骨移植的手术,例如脊椎融合手术和某些牙科应用。其延展性使其适合空间和精确度至关重要的微创手术。 DBM腻子在不需要结构支撑、需要最少干预和精确涂抹的情况下是首选。 DBM 腻子是一种更具延展性的解决方案,可涂布手术部位并根据需要成型。由于其多功能性,它被广泛用于各种骨骼修復手术,包括但不限于脊椎手术、骨折修復和关节重组。选择它是因为其多功能性和易用性,适用于需要生长因子输送和一定成型性的各种外科应用。含鬆质骨片的腻子是混合有鬆质骨片的DBM腻子,兼具骨诱导性和骨传导性,使其成为修復大块骨缺损和大规模重组手术的新选择。此尖端适用于需要改善可成形性、稳定性和骨癒合特性的各种骨骼修復手术。
DBM 在应用整形外科手术的快速普及
脊椎融合手术利用脱矿骨基质 (DBM) 促进脊椎骨融合。此应用利用 DBM 的骨诱导特性来刺激人体的自然骨形成机制。透过协助融合过程,DBM 促进脊椎稳定,并为患有退化性椎间盘疾病、椎间滑脱、脊椎等的患者提供缓解。 DBM 在牙科手术中有着重要的应用,特别是与植入和牙周修復相关的骨移植。 DBM 充当支架,支持缺损部位新骨的生长,提高人工植牙的稳定性和成功率,并帮助因牙周病流失的骨再生。在整形外科,DBM 可用于治疗骨缺损和骨折。 DBM 的骨传导和骨诱导特性对于需要骨再生和修復的情况至关重要。 DBM 在关节重组置换术中的使用,特别是髋关节和膝关节关节重建,有助于假体关节组件与宿主骨的整合。 DBM 应用于合成骨组件周围,以促进骨骼生长,从而植入并提高长期稳定性。在颅颚颜面手术中,DBM 用于修復创伤、先天性疾病或切除引起的骨缺损。它支持骨形成的能力对于这个复杂解剖区域的重组手术至关重要,从而获得卓越的功能和美学效果。
区域洞察
在美洲,特别是在美国,由于先进的医疗基础设施和骨骼相关疾病的高发病率,DBM 的使用受到严格监管但被广泛接受。该地区的生产遵循严格的 FDA 法规,确保产品的安全性和有效性。各大公司都拥有强大的研发投资和广泛的销售网络的支持。亚太地区市场正在快速成长,但其特点是监管环境多样化,以及因整形外科手术的兴起而带来的高需求。本土製造商不断涌现,利用 DBM 产品和区域客製化的成本优势。欧洲、中东和非洲市场根据国家的不同有不同的法规环境,是欧洲国家先进医疗保健系统与中东和非洲新兴市场的均衡融合。该地区的特点是拥有大量全球 DBM 参与者和适应当地医疗保健需求和合规标准的当地子公司。这些公司正在将 DBM 添加到其全面的骨移植产品组合中,从而实现更广泛的商业化。
FPNV定位矩阵
FPNV定位矩阵对于评估去矿骨基质市场至关重要。我们检视与业务策略和产品满意度相关的关键指标,以对供应商进行全面评估。这种深入的分析使用户能够根据自己的要求做出明智的决策。根据评估,供应商被分为四个成功程度不同的像限:前沿(F)、探路者(P)、利基(N)和重要(V)。
市场占有率分析
市场占有率分析是一种综合工具,可对脱矿骨基质市场供应商的现状进行深入而详细的研究。全面比较和分析供应商在整体收益、基本客群和其他关键指标方面的贡献,以便更好地了解公司的绩效及其在争夺市场占有率时面临的挑战。此外,该分析还提供了对该行业竞争特征的宝贵见解,包括在研究基准年观察到的累积、分散主导地位和合併特征等因素。这种详细程度的提高使供应商能够做出更明智的决策并制定有效的策略,从而在市场上获得竞争优势。
1. 市场渗透率:提供有关主要企业所服务的市场的全面资讯。
2. 市场开拓:我们深入研究利润丰厚的新兴市场,并分析其在成熟细分市场的渗透率。
3. 市场多元化:提供有关新产品发布、开拓地区、最新发展和投资的详细资讯。
4.竞争评估及资讯:对主要企业的市场占有率、策略、产品、认证、监管状况、专利状况、製造能力等进行综合评估。
5. 产品开发与创新:提供对未来技术、研发活动和突破性产品开发的见解。
1.脱矿骨基质市场规模及预测为何?
2.在去矿骨基质市场的预测期内,有哪些产品、细分市场、应用和领域需要考虑投资?
3.脱矿骨基质市场的技术趋势和法规结构是什么?
4.脱矿骨基质市场主要供应商的市场占有率为何?
5.进入脱矿骨基质市场合适的型态和策略手段是什么?
[186 Pages Report] The Demineralized Bone Matrix Market size was estimated at USD 671.14 million in 2023 and expected to reach USD 713.36 million in 2024, at a CAGR 6.54% to reach USD 1,046.37 million by 2030.
Demineralized bone matrix (DBM) is a type of bone graft material obtained from the collagen matrix of allogeneic bone, which has had its mineral content removed through an acid extraction process. This demineralization process exposes the bone's growth factors, particularly bone morphogenetic proteins (BMPs), making DBM osteoinductive and capable of promoting new bone formation. The primary factors contributing to the expansion of DBM use include its efficacy in bone repair and regeneration, its role as a graft extender in various orthopedic, dental, and spinal surgeries, and its potential to reduce the need for autografts, thus minimizing donor site morbidity. However, the variability in osteoinductive potential between different DBM products, the potential for immunogenic reaction, and the high costs associated with some DBM preparations pose significant challenges to their adoption. To address these restraints, ongoing research, and technological advancements focus on enhancing the consistency and osteoinductive potential of DBM products. Strategies include the development of composite grafts that combine DBM with synthetic or natural biomaterials to improve structural and functional properties and the application of advanced processing and sterilization techniques to preserve biological activity while ensuring safety. Expanding applications in emerging regions and integration with next-generation biologics signify dynamic growth avenues for the DBM, opening new doors for research, development, and clinical application.
KEY MARKET STATISTICS | |
---|---|
Base Year [2023] | USD 671.14 million |
Estimated Year [2024] | USD 713.36 million |
Forecast Year [2030] | USD 1,046.37 million |
CAGR (%) | 6.54% |
Product: Adoption of putty combined with cancellous chips form of DBM for extensive bone repair situations
DBM gel is a fluid-like formulation that allows for easy application in surgeries requiring precise bone graft placement, such as spinal fusion and certain dental applications. Its malleability makes it well-suited for minimally invasive procedures where space and precision are paramount. They are preferred in scenarios requiring minimal intervention and precise application without structural support. DBM putty offers a more malleable solution that can be applied to the surgical site and shaped as needed. Its versatility makes it widely used in a variety of bone repair procedures, including, but not limited to, spinal surgeries, fracture repair, and joint reconstruction. They are chosen for their versatility and ease of use in a broad range of surgical applications where both the delivery of growth factors and some degree of moldability are required. Putty combined with cancellous chips form combines DBM putty with cancellous bone chips, offering both osteoinductive and osteoconductive properties, making it an ideal choice for procedures requiring a scaffold for new bone growth, such as large bone defect repair and major reconstructive surgeries. They are preferred in extensive bone repair procedures where a blend of moldability, stability, and enhanced bone healing properties are needed.
Application: Exponential adoption of DBM for orthopedic surgical procedures
In spinal fusion surgery, a demineralized bone matrix (DBM) is utilized to promote the fusion of vertebrae. This application leverages the osteoinductive properties of DBM, which stimulate the body's natural bone-forming mechanisms. By aiding in the fusion process, DBM facilitates the stabilization of the spine, offering relief to patients with conditions such as degenerative disc disease, spondylolisthesis, and scoliosis. DBM finds significant applications in dental surgery, particularly in bone grafting procedures associated with dental implants and periodontal disease repair. It acts as a scaffold, supporting new bone growth in areas of deficiency, thus enhancing the stability and success rate of dental implants and aiding in the regeneration of bone lost to periodontal disease. Orthopedic surgery benefits from DBM in the treatment of bone defects and fractures. DBM's osteoconductive and osteoinductive characteristics are vital in scenarios where bone regeneration and repair are required. The use of DBM in joint reconstruction surgeries, particularly in hip and knee replacements, enhances the integration of the prosthetic components with the host bone. It is applied around the prosthetic components to promote bone ingrowth, thereby securing the implant and improving its long-term stability. In craniomaxillofacial procedures, DBM is used to repair bone defects resulting from trauma, congenital conditions, or resections. Its ability to support bone formation makes it an integral part of reconstructive surgeries in this complex anatomical region, contributing to both functional and aesthetic outcomes.
Regional Insights
In the Americas, particularly the United States, the use of DBM is highly regulated but widely accepted, driven by an advanced healthcare infrastructure and a high incidence of bone-related disorders. Production in this region is characterized by stringent FDA regulations, ensuring product safety and efficacy. Major companies are backed by robust R&D investments and expansive distribution networks. The APAC market, while rapidly growing, presents a contrast with a diverse regulatory landscape and a high need stemming from increasing orthopedic surgeries. Local manufacturers are emerging, leveraging cost advantages and regional customization of DBM products. The EMEA market, with its diverse regulatory environment across countries, shows a balanced blend of advanced healthcare systems in European countries and emerging markets in the Middle East and Africa. The region is marked by a strong presence of both global DBM players and local entities adapting to regional healthcare needs and compliance standards. They are working on including DBM with their comprehensive bone graft portfolio, enabling its wider commercialization.
FPNV Positioning Matrix
The FPNV Positioning Matrix is pivotal in evaluating the Demineralized Bone Matrix Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).
Market Share Analysis
The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the Demineralized Bone Matrix Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.
Key Company Profiles
The report delves into recent significant developments in the Demineralized Bone Matrix Market, highlighting leading vendors and their innovative profiles. These include Advanced Biotech Products P Ltd, AlloSource, Arthrex, Inc., Bioventus LLC, Cerapedics.Inc., Curasan AG, Exactech, Inc., Geistlich Pharma AG, Globus Medical, HansBioMed., Institut Straumann AG, Integra LifeSciences Holdings Corporation, Johnson & Johnson Services, Inc., KLS Martin SE & Co. KG, Kuros Biosciences Ltd., Medtronic PLC, NovaBone by Halma PLC, Orthofix Medical Inc., Osteogenics Biomedical, RTI Surgical Holdings, Inc., SpineWave, Inc., Stryker Corporation, Synerheal, XTANT Medical, and Zimmer Biomet.
Market Segmentation & Coverage
1. Market Penetration: It presents comprehensive information on the market provided by key players.
2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.
3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.
4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.
5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.
1. What is the market size and forecast of the Demineralized Bone Matrix Market?
2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the Demineralized Bone Matrix Market?
3. What are the technology trends and regulatory frameworks in the Demineralized Bone Matrix Market?
4. What is the market share of the leading vendors in the Demineralized Bone Matrix Market?
5. Which modes and strategic moves are suitable for entering the Demineralized Bone Matrix Market?
TA