市场调查报告书
商品编码
1466231
氧化压力测定市场:按产品和服务、测试类型、技术、最终用户、适应症分类 - 2024-2030 年全球预测Oxidative Stress Assay Market by Product & Service (Consumables, Instruments, Services), Test Type (Antioxidant Capacity Assays, Enzyme-Based Assays, Indirect Assays), Technology, End-user, Indication - Global Forecast 2024-2030 |
※ 本网页内容可能与最新版本有所差异。详细情况请与我们联繫。
氧化压力检测市场规模预计2023年为10.6亿美元,预计2024年将达到11.7亿美元,2030年将达到21.9亿美元,复合年增长率为10.85%。
氧化压力测定是一种评估体内活性氧(ROS)产生和抗氧化防御机制之间平衡的生物分析方法。这些测定对于了解氧化压力在细胞过程、疾病进展和治疗效果中的作用至关重要。氧化压力测定对于了解氧化压力是神经退化性疾病、心血管疾病、癌症和老化过程等病理学的重要贡献者。对氧化压力测定的需求显着增加,因为活性氧透过细胞代谢活动不断产生并与细胞成分相互作用,损害蛋白质、核酸和脂质,导致细胞功能障碍和细胞死亡。此外,与氧化压力相关的慢性疾病的盛行率不断增加,增加了对能够早期检测和治疗指导的强大诊断工具的需求。然而,先进诊断技术的高成本以及各种检测平台缺乏标准化通讯协定导致结果不一致,极大地阻碍了氧化压力检测的采用。此外,对体外诊断和就地检验技术的需求不断增长,为扩大氧化压力测定在临床环境中的应用提供了巨大的潜力。开发与先进检测系统整合的便携式、易于使用的可携式可以简化早期诊断并实现更快的治疗性介入。这些检测平台与机器学习演算法和人工智慧 (AI) 相结合,可以帮助提高对复杂疾病机制的理解并确定新的治疗标靶。
主要市场统计 | |
---|---|
基准年[2023] | 10.6亿美元 |
预测年份 [2024] | 11.7亿美元 |
预测年份 [2030] | 21.9亿美元 |
复合年增长率(%) | 10.85% |
产品和服务最终用途领域对消耗品的需求不断增长
氧化压力测定耗材包括试剂、套件、酵素、探针以及检测和测量氧化压力标记物所需的其他材料。学术研究机构和临床实验室需要高品质的氧化压力测定耗材,这些耗材既要经济高效,又要提供准确的结果。用于氧化压力测定的仪器包括微孔盘、光强度、萤光、光强度、流式细胞仪和高内涵筛检系统,可灵敏地检测氧化压力生物标记。氧化压力测定服务涉及将您的研究计划外包给提供测定开发、验证、样品测试、资料分析和解释服务的受託研究机构(CRO) 或核心设施。研究人员更喜欢熟悉氧化压力测定并拥有成功计划记录的服务供应商,以确保结果可靠。
测试类型抗氧化能力测量的需求不断增长
抗氧化能力测定评估检体清除自由基和其他活性物质的整体能力,从而了解整体抗氧化能力。评估各种抗氧化剂(包括亲水性和亲油性化合物)的能力是这些测定的基于必要性的偏好。基于酵素的测定可测量特定氧化酵素的活性,这些酵素在维持细胞氧化还原平衡中发挥重要作用。当研究人员旨在研究特定酶途径或确定各种干预措施对酶活性的影响时,这些测定是首选。间接测定透过测量氧化过程中产生的副产物来评估氧化压力,当由于浓度低或担心与目标分子的反应性而难以直接检测时,间接测定非常有用。基于活性氧的测定旨在直接检测特定的活性氧分子。研究人员更喜欢用这种方法来测量各种实验条件下单一活性氧的水平。
酵素结合免疫吸附检测法(ELISA) 技术的日益普及
层析法是一种广泛使用的分离技术,用于定量和鑑定内源性或外源性添加的活性氧标记物,例如脂肪过氧化产物、麸胺基硫和其他抗氧化剂。酵素结合免疫吸附检测法(ELISA)是一种基于酵素的测试,使用特异性抗体来测量生物检体中的氧化压力生物标记物,具有高灵敏度和选择性。 ELISA 方法的主要优点是其简单、处理时间快以及适合高通量筛检。流式细胞技术是一种强大的多参数技术,用于使用与活性氧和其他细胞标记物反应的萤光染料测量单细胞水平的氧化压力。该技术能够对 ROS 水平、粒线体电位和细胞活力等多个参数进行高通量即时分析。高内涵筛检(HCS) 是一种基于成像的先进方法,它将萤光显微镜与自动影像撷取和分析相结合,以监测活细胞中的氧化压力。利用这项技术,研究人员可以同时评估多个终点,例如活性氧的产生、抗氧化反应和细胞型态的变化,从而获得更高水平的资讯。无标定检测技术,例如表面等离子共振 (SPR)、生物层干涉测量 (BLI) 和电化学方法,提供了非侵入性替代方法来量化不需要萤光标记的氧化压力生物标记。这些技术可以即时监测分子间相互作用,并且可以直接研究自然状态下的功能活动。共聚焦显微镜、电子显微镜和原子力显微镜等显微技术用于可视化细胞内 ROS 的产生和定位。
氧化压力测定在最终用户製药和生物技术公司中的普及
氧化压力测定主要用于学术研究机构研究活性氧在癌症、神经退化性疾病和心血管疾病等各种疾病中的功能。临床实验室对于诊断和个人化医疗至关重要,需要进行氧化压力测定来评估患者的抗氧化状态,评估药物的有效性,并监测与氧化压力相关的疾病的治疗结果。委外研发机构(CRO) 为製药和生技公司提供研究外包服务,同时在不影响品质标准的情况下保持成本效率。在 CRO 进行的临床前研究中,氧化压力测定透过监测药物开发过程中可能导致细胞损伤的活性氧水平,在评估药物安全性和有效性方面发挥重要作用。製药和生物技术公司正在大力投资研发,以发现针对氧化压力相关疾病的创新疗法。
扩大氧化压力检测法在呼吸系统疾病适应症检测的应用
氧化压力会影响癌症的发生和进展,因为它会诱发 DNA 损伤并导致基因突变。癌症研究需要检测活性氧 (ROS)、评估抗氧化能力以及评估麸胺基硫和丙二醛等特定生物标记。在心血管疾病 (CVD) 中,氧化还原稳态失衡会导致内皮功能障碍、发炎和斑块形成。在 CVD 研究中,测量一氧化氮 (NO) 的产生和脂肪过氧化对于更好地了解潜在的疾病机制至关重要。糖尿病的慢性高血糖会增加氧化压力,导致组织损伤和併发症,如神经病变、肾臟病变和视网膜病变。氧化压力也与气喘、特发性肺纤维化(IPF)和慢性阻塞性肺病(COPD)等疾病有关。该领域的关键优先领域包括测量支气管上皮细胞中ROS产生的测定以及检测与氧化性肺损伤相关的生物标记的测定。
区域洞察
在美洲地区,人们对活性氧 (ROS) 的认识不断提高,慢性病盛行率不断上升,以及对先进氧化压力检测方法开发的投资增加,正在推动氧化压力检测方法的采用。各个学术机构正在广泛研究疾病进展和老化中的氧化压力。 Thermo Fisher Scientific, Inc. 和 Merck KGaA 等製造商正专注于合作研究活动,以扩大其质谱产品组合併巩固其在氧化压力测定市场的地位。在亚太地区(APAC),由于印度和中国等新兴国家的经济开拓,氧化压力检测市场正在快速成长。由于强大的研发投资以及 Abnova Corporation 和FUJIFILM Wako Pure Chemical 等主要製造商的存在,中国和日本已成为氧化压力测定市场的主要参与者。由于製药和生物技术公司的强大存在以及政府对研究计划的资助,欧洲氧化压力测定市场在欧洲、中东和非洲地区得到了显着发展。由于慢性病的增加和人口老化,欧盟(EU)国家正在积极投资氧化压力检测的开发。欧盟成员国之间的监管协调实现了产品核可和创新支援的简化方法。由于医疗基础设施的改善,中东正在经历显着成长,而非洲则越来越关注非传染性疾病,为未来的市场扩张提供了机会。
FPNV定位矩阵
FPNV定位矩阵对于评估氧化压力检测市场至关重要。我们检视与业务策略和产品满意度相关的关键指标,以对供应商进行全面评估。这种深入的分析使用户能够根据自己的要求做出明智的决策。根据评估,供应商被分为四个成功程度不同的像限:前沿(F)、探路者(P)、利基(N)和重要(V)。
市场占有率分析
市场占有率分析是一种综合工具,可以对氧化压力测定市场中供应商的现状进行深入而详细的研究。全面比较和分析供应商在整体收益、基本客群和其他关键指标方面的贡献,以便更好地了解公司的绩效及其在争夺市场占有率时面临的挑战。此外,该分析还提供了对该行业竞争特征的宝贵见解,包括在研究基准年观察到的累积、分散主导地位和合併特征等因素。这种详细程度的提高使供应商能够做出更明智的决策并制定有效的策略,从而在市场上获得竞争优势。
1. 市场渗透率:提供有关主要企业所服务的市场的全面资讯。
2. 市场开拓:我们深入研究利润丰厚的新兴市场,并分析其在成熟细分市场的渗透率。
3. 市场多元化:提供有关新产品发布、开拓地区、最新发展和投资的详细资讯。
4. 竞争评估和情报:对主要企业的市场占有率、策略、产品、认证、监管状况、专利状况和製造能力进行全面评估。
5. 产品开发与创新:提供对未来技术、研发活动和突破性产品开发的见解。
1.氧化压力检测市场的市场规模与预测是多少?
2.在氧化压力检测市场的预测期内,有哪些产品、细分市场、应用和领域需要考虑投资?
3.氧化压力检测市场的技术趋势和法规结构是什么?
4.氧化压力检测市场主要供应商的市场占有率是多少?
5. 进入氧化压力检测市场的合适型态和策略手段是什么?
[183 Pages Report] The Oxidative Stress Assay Market size was estimated at USD 1.06 billion in 2023 and expected to reach USD 1.17 billion in 2024, at a CAGR 10.85% to reach USD 2.19 billion by 2030.
The oxidative stress assay is a bioanalytical method to evaluate the balance between reactive oxygen species (ROS) production and the antioxidant defense mechanisms within biological systems. These assays are essential for understanding oxidative stress's role in cellular processes, disease progression, and treatment efficacy. Oxidative stress assay is crucial in understanding oxidative stress, a significant contributor to pathological conditions such as neurodegenerative diseases, cardiovascular disorders, cancer, and aging processes. The constant generation of ROS through cellular metabolic activities and their interaction with cellular components cause harm to proteins, nucleic acids, and lipids, leading to cell dysfunction or cell death, significantly increasing the need for oxidative stress assays. Moreover, the rising prevalence of chronic diseases associated with oxidative stress has increased the demand for robust diagnostic tools that enable early detection and treatment guidance. However, high costs associated with advanced diagnostic technologies and the lack of standardized protocols across various assay platforms result in inconsistent results, significantly impeding the adoption of oxidative stress assays. In addition, the growing demand for in vitro diagnostics and point-of-care testing technologies presents a vast potential for expanding the application of oxidative stress assays in clinical settings. Developing portable, easy-to-use devices integrated with advanced detection systems can streamline early diagnosis and enable faster therapeutic interventions. Combining machine learning algorithms and artificial intelligence (AI) into these assay platforms facilitates a greater understanding of complex disease mechanisms and helps identify novel therapeutic targets.
KEY MARKET STATISTICS | |
---|---|
Base Year [2023] | USD 1.06 billion |
Estimated Year [2024] | USD 1.17 billion |
Forecast Year [2030] | USD 2.19 billion |
CAGR (%) | 10.85% |
Product & Service: Rising demand for consumables across end-use sectors
Consumables for oxidative stress assays include reagents, kits, enzymes, probes, and other materials required to detect and measure oxidative stress markers. Academic research institutes and clinical laboratories require high-quality consumables for oxidative stress assays that cost-effectively produce accurate results. Instruments used in oxidative stress assays include microplate readers, spectrophotometers, fluorometers, luminometers, flow cytometers, and high-content screening systems that sensitively detect oxidative stress biomarkers. Oxidative stress assay services involve outsourcing research projects to contract research organizations (CROs) or core facilities offering assay development, validation, sample testing, data analysis, and interpretation services. Researchers prefer service providers with expertise in oxidative stress assays and a proven track record of successful projects to ensure reliable results.
Test Type: Increasing demand for antioxidant capacity assays
Antioxidant capacity assays evaluate the overall capacity of a specimen to scavenge free radicals and other reactive species, providing an understanding of the total antioxidant potential. The need-based preference for these assays lies in their ability to evaluate various antioxidants, including hydrophilic and lipophilic compounds. Enzyme-based assays measure the activity of specific antioxidant enzymes that play crucial functions in maintaining cellular redox balance. These assays are preferred when researchers aim to investigate particular enzymatic pathways or determine the effect of various interventions on enzyme activity. Indirect assays are employed to evaluate oxidative stress by measuring by-products generated during oxidation processes, which are helpful when direct detection is difficult due to low concentration or reactivity concerns with target molecules. Reactive oxygen species-based assays are designed to detect specific ROS molecules directly. The researchers prefer them to determine the levels of individual ROS species under various experimental conditions.
Technology: Emerging popularity of Enzyme-linked Immunosorbent Assay (ELISA)
Chromatography is a widespread separation technique used that quantifies and identifies endogenous or exogenously added ROS markers such as lipid peroxidation products, glutathione, and other antioxidants. Enzyme-linked immunosorbent assay (ELISA) is an enzyme-based test that utilizes specific antibodies to measure oxidative stress biomarkers in biological samples with high sensitivity and selectivity. The significant advantage of ELISA is its simplicity, fast processing time, and adaptability to high-throughput screening. Flow cytometry is a powerful multi-parameter technique used to measure oxidative stress at the single-cell level using fluorescent dyes that react with ROS or other cellular markers. This technology offers high-throughput and real-time analysis of multiple parameters such as ROS levels, mitochondrial potential, and cell viability. High-content screening (HCS) is an advanced imaging-based method that combines fluorescence microscopy with automated image acquisition and analysis to monitor oxidative stress in living cells. Researchers can assess multiple endpoints simultaneously with this technology, such as ROS production, antioxidant responses, and cell morphology changes, contributing to higher content information. Label-free detection technologies, including surface plasmon resonance (SPR), bio-layer interferometry (BLI), or electrochemical methods, offer non-invasive alternatives to quantify oxidative stress biomarkers without the need for fluorescent labels. These techniques provide real-time monitoring of molecular interactions and allow for studying functional activity directly in their natural state. Microscopy techniques such as confocal, electron, or atomic force microscopy are used to visualize intracellular ROS production and localization.
End-user: Penetration of oxidative-stress-assay in pharmaceutical and biotechnology companies
Academic research institutes primarily use oxidative stress assays to investigate the function of reactive oxygen species (ROS) in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. Clinical laboratories are essential in diagnostics and personalized medicine, which require oxidative stress assays to evaluate patients' antioxidant status, assess drug efficacy, or monitor treatment outcomes for conditions associated with oxidative stress. Contract research organizations (CROs) provide research outsourcing services to pharmaceutical and biotech companies while maintaining cost efficiency without compromising quality standards. Oxidative stress assays play an important role in preclinical studies conducted by CROs to assess drug safety and efficacy by monitoring ROS levels with the potential to cause cellular damage during drug development. Pharmaceutical and biotechnology companies heavily invest in research and development to discover innovative therapeutics targeting oxidative stress-related diseases.
Indication: Expanding use of oxidative-stress-assay for detecting respiratory diseases
Oxidative stress is consequential in cancer development and progression, as it can induce DNA damage, leading to genetic mutations. Need-based preferences for cancer research include detecting reactive oxygen species (ROS), assessing antioxidant capacity, and evaluating specific biomarkers, including glutathione or malondialdehyde. In cardiovascular diseases (CVDs), imbalanced redox homeostasis contributes to endothelial dysfunction, inflammation, and plaque formation. Assays measuring nitric oxide (NO) production or lipid peroxidation are essential for CVD research to understand the underlying disease mechanisms better. Chronic hyperglycemia in diabetes increases oxidative stress, causing tissue damage and complications such as neuropathy, nephropathy, and retinopathy. Oxidative stress is implicated in conditions such as asthma, idiopathic pulmonary fibrosis (IPF), and chronic obstructive pulmonary disease (COPD). Key preference areas in this field include assays for measuring ROS production in bronchial epithelial cells or detecting biomarkers related to oxidative lung injury.
Regional Insights
In the Americas region, increased awareness and research on reactive oxygen species (ROS), the rising prevalence of chronic diseases, and growing investments in developing advanced oxidative stress assays have raised the adoption of oxidative stress assays in the region. Various academic institutions have extensively studied oxidative stress in disease progression and aging. The presence of manufacturers such as Thermo Fisher Scientific, Inc. and Merck KGaA focus on collaboration activities to expand its mass spectrometry portfolio, thereby strengthening its position in the oxidative stress assay market. The Asia-Pacific (APAC) region witnessed rapid oxidative stress assay market growth due to expansive economic development across emerging nations such as India and China. China and Japan have established themselves as key players in the oxidative stress assay market with strong R&D investments and the presence of key manufacturers such as Abnova Corporation and Fujifilm Wako Pure Chemical Corporation. Europe's oxidative stress assay market significantly developed in the EMEA region due to its strong presence of pharmaceutical and biotechnology companies and government funding for research projects. The European Union (EU) countries actively invest in oxidative stress assay development due to the rising incidences of chronic disorders and an aging population. Regulatory harmonization across EU member states has enabled a streamlined approach towards product approvals and innovation support. The Middle East is witnessing significant growth due to improving healthcare infrastructure, while Africa's emerging focus on non-communicable diseases presents opportunities for future market expansion.
FPNV Positioning Matrix
The FPNV Positioning Matrix is pivotal in evaluating the Oxidative Stress Assay Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).
Market Share Analysis
The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the Oxidative Stress Assay Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.
Key Company Profiles
The report delves into recent significant developments in the Oxidative Stress Assay Market, highlighting leading vendors and their innovative profiles. These include Abcam PLC, Agilent Technologies, Inc., AMS Biotechnology, Arbor Assays Inc., Assay Genie, Bio-Rad Laboratories, Inc., Bio-Techne Corporation, BioAssay Systems, Biomedica Medizinprodukte GmbH, BPS Bioscience, Inc., Callegari Srl, Cayman Chemical Company, Cell Biolabs, Inc., Cytek Biosciences, Inc., Eagle Biosciences, Inc., Enzo Biochem, Inc., Ethos Biosciences, Inc., Geno Technology Inc., Genox Corporation, Helvetica Health Care Sarl, Hycult Biotech Inc., Kamiya Biomedical Company, Labstat Inc., Merck KGaA, Oxford Biomedical Research, Inc., Promega Corporation, Qiagen N.V., Thermo Fisher Scientific, Inc., Vivid Microscopy, LLC, and ZenBio, Inc..
Market Segmentation & Coverage
1. Market Penetration: It presents comprehensive information on the market provided by key players.
2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.
3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.
4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.
5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.
1. What is the market size and forecast of the Oxidative Stress Assay Market?
2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the Oxidative Stress Assay Market?
3. What are the technology trends and regulatory frameworks in the Oxidative Stress Assay Market?
4. What is the market share of the leading vendors in the Oxidative Stress Assay Market?
5. Which modes and strategic moves are suitable for entering the Oxidative Stress Assay Market?