市场调查报告书
商品编码
1468024
数位 PCR 和即时PCR市场:按类型、产品类型、应用和最终用户 - 2024-2030 年全球预测Digital PCR & Real-Time PCR Market by Type (dPCR, qPCR), Product Type (Instruments, Reagents & Consumables, Services), Application, End-User - Global Forecast 2024-2030 |
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数位PCR和即时PCR市场规模预计到2023年为82.4亿美元,2024年达到88.7亿美元,预计2030年将达到141.1亿美元,复合年增长率为7.98%。
数位 PCR (dPCR) 和即时PCR,通常称为定量 PCR (qPCR),是聚合酵素链锁反应(PCR) 科学广泛领域中体现的两项关键技术。数位 PCR (dPCR) 是一种用于绝对定量核酸的先进分子生物学技术,涉及将样本细分为许多包含 0 或 1 个模板分子的单独小反应。即时PCR,也称为定量PCR(qPCR),与标准PCR的不同之处在于可以即时检测扩增产物反应的累积。由于这些技术在检测低水平病原体和稀有基因序列方面具有高精度和敏感性,因此需求量很大。对早期准确诊断的需求迅速增加,遗传疾病和感染疾病的扩散正在导致数位 PCR 和即时PCR市场的成长。此外,COVID-19 大流行特别凸显了基于 PCR 的诊断在管理感染疾病爆发方面的关键作用。儘管数位 PCR 和即时PCR市场不断增长,但仍面临一些限制,例如液滴大小和型态的变化,这影响了方法的稳健性,以及新兴经济体对专业知识的需求。然而,市场参与企业对研发的投资不断增加,以及提供高精度和灵敏度的液滴数位 PCR (ddPCR) 技术的出现,为数位 PCR 和即时PCR市场的成长带来了前景。
主要市场统计 | |
---|---|
基准年[2023] | 82.4亿美元 |
预测年份 [2024] | 88.7亿美元 |
预测年份 [2030] | 141.1亿美元 |
复合年增长率(%) | 7.98% |
qPCR 的高通量和宽动态范围日益偏好
数位 PCR 透过将样本分为数千个单独的反应,每个反应包含零个、一个或几个模板分子,从而可以对核酸进行绝对定量。 PCR 后,对含有扩增 DNA 的分区进行计数,描述直接、准确的定量,无需标准曲线或参考样本。即时PCR,通常称为定量 PCR 或 qPCR,是分子生物学中广泛使用的技术,可扩增并同时定量目标 DNA 分子。 qPCR 的一个关键特征是使用萤光染料或探针。萤光染料或探针与 DNA 结合,可以随着反应的进行定量。
产品类型:对专用套件的需求不断增加,以满足专业最终用户的需求
在数位 PCR 和即时PCR市场中,设备是研究人员为各种应用扩增 DNA 和 RNA 的必备产品。样品分裂系统用于将样品分裂成数千个独立的小液滴。另一方面,聚合酵素连锁反应热迴圈仪用于透过聚合酵素链锁反应扩增部分样品,封板机用于密封PCR板,以尽量减少扩增过程中样品的蒸发。试剂和耗材是数位 PCR 和即时PCR技术的重要组成部分,包括这些工作流程中使用的所有必要化学品和一次性材料。这包括用于 dPCR 和 qPCR 应用的各种酵素、引子、缓衝液和预混液。这些试剂的品质直接影响 dPCR 和 qPCR 技术的准确性、灵敏度和重现性。同样,PCR 管、板和密封等耗材的设计可确保与各种 dPCR 和 qPCR 仪器相容,同时防止日常业务所必需的交叉污染和样品损失。数位 PCR 和即时PCR市场得到了从开发到验证和样本测试的一系列服务的补充,可满足客户的多样化需求。外包 dPCR 和 qPCR 服务使最终用户能够最大限度地降低实验室设置的前期成本,同时促进经过认证的专业服务供应商开发客製化解决方案。
应用:在法医学方面具有巨大潜力,例如亲子鑑定和犯罪现场调查中低水平 DNA 的检测
在临床研究领域,数位 PCR (dPCR) 和即时PCR(qPCR) 在促进疾病理解和治疗方面发挥重要作用。这些技术因其高精度和强大功能而被专门采用,使其可用于检测罕见突变和拷贝数变异以及监测微小残留疾病。此外,快速可靠的基因表现定量可以帮助疾病分层、监测治疗效果以及检验疾病进展和治疗反应的生物标记。法医实验室严重依赖 qPCR 的特异性和灵敏度来进行 DNA 分析、检测微量遗传物质以及在序列测定前对 DNA 进行定量。 dPCR 和 qPCR 的出现进一步完善了法医分析,增强了低水平病原体的检测和混合 DNA 样本的分析。在研究实验室中,dPCR 和 qPCR 是基因组、功能基因体学和分子生物学研究的重要工具。这些技术对于检验次世代定序仪的结果、研究基因编辑的结果以及探索病毒感染和微生物定量的动态至关重要。
最终使用者:dPCR 和 qPCR 在个人化药物开发中的重要应用
数位PCR和即时PCR方法在定量基因表现分析、定序结果检验和单细胞分析方面具有高精度和准确性,在学术研究中发挥至关重要的作用。 dPCR 提供的资料粒度对于检测稀有等位基因和了解单分子水平的变异特别有用,而 qPCR 的快速即时资料功能使其可用于快速实验复製和教育应用。在农业和生命科学领域,数位 PCR 和即时PCR是遗传分析、基因改造作物(GMO) 检测和病原体鑑定的重要工具。 dPCR 在量化 DNA 变异方面具有无与伦比的灵敏度,这是作物改良计划中性状选择的基础,而qPCR 用于监测植物和牲畜的疾病爆发,提高农业生产力和生物安全性,因其多功能性和快速通量而被广泛应用。 CRO和CDMO利用数位PCR和即时PCR技术为药物开发提供生物标记发现、临床试验支援和品管等专业服务。医院和诊断实验室依靠即时PCR提供的快速、准确的诊断来检测感染疾病、遗传疾病和癌症生物标记。在临床环境中,qPCR 的轻鬆整合和快速週转时间对于患者管理决策至关重要。数位 PCR 和即时PCR在药物和生物製药研发中对于药物发现验证、药物基因体学和製造过程中的品管至关重要。 dPCR 的高解析度对于低丰度标靶的准确定量以及评估可能影响药物功效或安全性的基因表现的微小变化特别有用。 qPCR 的适应性为药物发现和药物开发中的高通量筛检和验证提供了可靠的方法,从而简化了药物研发流程。
区域洞察
强大的生物技术和製药行业、政府对医学研究的大力投资以及技术先进的诊断技术的广泛采用正在推动美洲数位 PCR 的成长,即时PCR市场也呈现强劲增长。由于需要先进的能力来对抗感染疾病、遗传疾病和各种癌症的传播,欧洲数位 PCR 和即时PCR市场正在稳步增长。先进的医疗基础设施和生物技术领域研发活动的大量投资正在支持该地区的市场扩张。中东和非洲地区的成长是由医疗设施改善、经济发展和创新诊断技术的普及所推动的。亚太地区是 dPCR 和 qPCR 技术成长最快的区域市场。这一成长主要归功于中国、日本、印度、韩国和澳洲等国家生物医药产业的扩张。由于该地区人口众多,对包括 dPCR 和 qPCR 在内的先进诊断方法有很高的需求。政府在医疗保健方面的支出增加和慢性病盛行率的上升进一步推动了该地区的市场成长。
FPNV定位矩阵
FPNV定位矩阵对于评估数位PCR和即时PCR市场至关重要。我们检视与业务策略和产品满意度相关的关键指标,以对供应商进行全面评估。这种深入的分析使用户能够根据自己的要求做出明智的决策。根据评估,供应商被分为四个成功程度不同的像限。最前线 (F)、探路者 (P)、利基 (N) 和重要 (V)。
市场占有率分析
市场占有率分析是一种综合工具,可对数位 PCR 和即时PCR市场供应商的现状进行深入而深入的研究。全面比较和分析供应商在整体收益、基本客群和其他关键指标方面的贡献,以便更好地了解公司的绩效及其在争夺市场占有率时面临的挑战。此外,该分析还提供了对该细分市场竞争特征的宝贵见解,包括在研究基准年观察到的累积、碎片化主导地位和合併特征等因素。这种详细程度的提高使供应商能够做出更明智的决策并制定有效的策略,从而在市场上获得竞争优势。
1. 市场渗透率:提供有关主要企业所服务的市场的全面资讯。
2. 市场开拓:我们深入研究利润丰厚的新兴市场,并分析其在成熟细分市场的渗透率。
3. 市场多元化:包括新产品发布、开拓地区、最新发展和投资的详细资讯。
4.竞争力评估及资讯:对主要企业的市场占有率、策略、产品、认证、监管状况、专利状况、製造能力等进行全面评估。
5. 产品开发与创新:包括对未来技术、研发活动和突破性产品开发的智力见解。
1. 数位PCR和即时PCR市场的市场规模和预测是多少?
2. 在数位PCR和即时PCR市场的预测期内,我们应该考虑投资哪些产品和应用?
3. 数位PCR和即时PCR市场的技术趋势和法规结构是什么?
4.数位PCR和即时PCR市场主要厂商的市场占有率是多少?
5. 进入数位PCR和即时PCR市场的合适型态和策略手段是什么?
[194 Pages Report] The Digital PCR & Real-Time PCR Market size was estimated at USD 8.24 billion in 2023 and expected to reach USD 8.87 billion in 2024, at a CAGR 7.98% to reach USD 14.11 billion by 2030.
Digital PCR (dPCR) and real-time PCR, often referred to as quantitative PCR (qPCR), are two pivotal techniques bodied under the broader field of polymerase chain reaction (PCR) science. Digital PCR (dPCR) is an advanced molecular biology technique for the absolute quantification of nucleic acids, which includes subdividing the sample into many individual, smaller reactions that contain either zero or one template molecule. Real-Time PCR, known as quantitative PCR (qPCR), differs from standard PCR by enabling the detection of the accumulation of amplification product reaction as it occurs in real-time. These techniques are in high demand owing to their heightened precision and sensitivity for detecting low-level pathogens and rare genetic sequences. The surge in the need for early and precise diagnosis and an uptick in genetic disorders and infectious diseases has led to the growth of the digital PCR & real-time PCR market. Further, the COVID-19 pandemic particularly highlighted the critical role of PCR-based diagnostics in managing infectious outbreaks. Despite its growth, the digital PCR & real-time PCR market contend with limitations, including the variability in the size and shape of droplets, which affect the robustness of the method and the need for specialized expertise in developing economies. However, growing investments by industry participants in R&D and the emergence of droplet digital PCR (ddPCR) technology for exquisite precision and sensitivity promise future prospects for the digital PCR & real-time PCR market growth.
KEY MARKET STATISTICS | |
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Base Year [2023] | USD 8.24 billion |
Estimated Year [2024] | USD 8.87 billion |
Forecast Year [2030] | USD 14.11 billion |
CAGR (%) | 7.98% |
Type: Higher preferences for qPCR for high throughput and a broader dynamic range
Digital PCR allows absolute quantification of nucleic acids by partitioning the sample into thousands of separate reactions, with each containing zero, one, or a few template molecules. Post PCR, the number of partitions containing amplified DNA is counted, providing direct and precise quantification without the need for standard curves or reference samples. Real-time PCR, often referred to as quantitative PCR or qPCR, is a technology widely used in molecular biology to amplify and simultaneously quantify a targeted DNA molecule. A key feature of qPCR is the use of fluorescent dyes or probes, which bind to the DNA and allow quantification as the reaction progresses.
Product Type: Growing demand for application-specific kits that address the needs of specialized end-users
Within the digital PCR & real-time PCR market, instruments are the vital products that enable researchers to amplify DNA and RNA for various applications. Sample partitioning systems are used to divide the sample into thousands of separate, small droplets. Whereas, thermal cyclers are deployed to amplify segments of the sample via the polymerase chain reaction, and plate sealers are used to seal PCR plates to minimize sample evaporation during amplification. Reagents and consumables represent a critical segment of digital PCR & real-time PCR technologies, encompassing all necessary chemicals and disposable materials used in these workflows. This includes a variety of enzymes, primers, buffers, and master mixes tailored for dPCR and qPCR applications. The quality of these reagents directly impacts the accuracy, sensitivity, and repeatability of dPCR and qPCR techniques. Likewise, the consumables, such as PCR tubes, plates, and seals, are designed to ensure compatibility with different dPCR and qPCR instruments while preventing cross-contamination and sample loss and are essential for the day-to-day operation of any laboratory engaged in molecular testing. The digital PCR & real-time PCR market is complemented by an array of services that cater to customers' diverse needs, from development, validation, and sample testing. Outsourcing dPCR and qPCR services minimizes upfront costs of laboratory setup for end-users while facilitating the development of customized solutions from authorized and expert service providers.
Application: Higher potential in forensics for paternity testing and the detection of low-level DNA in crime scene investigations
In the realm of clinical research, both digital PCR (dPCR) and real-time PCR (qPCR) serve critical roles in advancing our understanding and treatment of diseases. These techniques are particularly adopted for their high precision and ability, making them valuable for detecting rare mutations, copy number variations, and monitoring minimal residual disease. Further, their rapid and reliable quantification of gene expression helps with disease stratification, monitoring treatment efficacy, and validating biomarkers for disease progression and therapeutic response. Forensic laboratories rely heavily on the specificity and sensitivity of qPCR for DNA profiling, detecting minute traces of genetic material, and quantifying DNA prior to sequencing. The advent of dPCR and qPCR has further refined forensic analysis, enhancing the detection of low-level pathogens and analysis of mixed DNA samples. At research institutes, dPCR and qPCR are indispensable tools for genomic research, functional genomics, and molecular biology studies. These techniques are crucial for validating findings from next-generation sequencing, studying gene-editing outcomes, and probing the dynamics of viral infections and microbial quantification.
End-User: Significant applications of dPCR & qPCR in the personalized drug development he
Digital PCR and real-time PCR methods are pivotal in academic research for their high precision and accuracy in quantitative gene expression analysis, validation of sequencing results, and single-cell analysis. The granularity of data provided by dPCR is especially valuable for detecting rare alleles and understanding variations at the single-molecule level in scientific studies, while qPCR's rapid real-time data capabilities allow for swift experimental iterations and educational applications. In the agriculture and life sciences sector, digital PCR and real-time PCR are indispensable tools for genetic trait analysis, genetically modified organism (GMO) detection, and pathogen identification. dPCR offers unparalleled sensitivity in quantifying DNA alterations that underpin trait selection in crop improvement programs, while qPCR is widely used for its versatility and rapid throughput in monitoring disease outbreaks in plants and livestock, ensuring agricultural productivity and biosecurity. CROs and CDMOs utilize digital and real-time PCR techniques to offer specialized services, such as biomarker discovery, clinical trial support, and quality control for drug development. Hospitals and diagnostic laboratories rely on the rapid and accurate diagnostics afforded by real-time PCR to detect infectious diseases, genetic disorders, and cancer biomarkers. In the clinical environment, the ease of integration and rapid turnaround time of qPCR are critical for patient management decisions. Digital PCR and real-time PCR are essential in pharmaceutical and biopharmaceutical research and development for drug target validation, pharmacogenomics, and quality control during manufacturing processes. The fine resolution of dPCR is particularly beneficial in the precise quantitation of low-abundance targets and in assessing minor variations in gene expression that may influence drug efficacy and safety. qPCR's adaptability streamlines the pharmaceutical pipeline by offering a robust method for high-throughput screening and validation in drug discovery and development.
Regional Insights
In the Americas, the digital PCR & real-time PCR market is showing robust growth, attributed to the region's strong biotechnology and pharmaceutical sectors, active government investments in healthcare research, and the wide adoption of technologically advanced diagnostic methods. The European market for digital PCR & real-time PCR is witnessing steady growth owing to the need for advanced capabilities to counter the increasing prevalence of infectious diseases, genetic disorders, and various types of cancer. Advanced healthcare infrastructure and significant investments in R&D activities in the biotechnology sector underpin the market expansion in the region. The growth in the Middle East and Africa is propelled by improving healthcare facilities, economic development, and increased access to innovative diagnostic technologies. The Asia-Pacific is emerging as the fastest-growing regional market for dPCR and qPCR technologies. The growth is largely fueled by the expanding biomedical industry in countries such as China, Japan, India, South Korea, and Australia. The region's large population base presents a significant demand for advanced diagnostic methods including dPCR and qPCR. Increased government expenditure on healthcare and the rising prevalence of chronic diseases are further catalyzing the market growth in the region.
FPNV Positioning Matrix
The FPNV Positioning Matrix is pivotal in evaluating the Digital PCR & Real-Time PCR Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).
Market Share Analysis
The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the Digital PCR & Real-Time PCR Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.
Key Company Profiles
The report delves into recent significant developments in the Digital PCR & Real-Time PCR Market, highlighting leading vendors and their innovative profiles. These include Abbott Laboratories, Inc., Agilent Technologies, Inc., Analytik Jena GmbH+Co. KG, Azure Biosystems Inc., Becton, Dickinson and Company, Bio-Rad Laboratories, Inc., Biocompare by CompareNetworks, Inc., BIOMERIEUX S.A., Bioneer Corporation, Danaher Corporation, ELITech Group, Enzo Life Sciences, Inc., Eppendorf SE, Etcon Analytical and Environmental Systems & Services Ltd., Explorea s.r.o, F. Hoffmann-La Roche AG, Global Engage Sdn. Bhd., Hangzhou Longgene Scientific Instruments Co., Ltd., Heal Force Bio-Meditech Holdings Limited, Integrated DNA Technologies, Inc., LABGENE Scientific SA, Merck KGaA, Meridian Bioscience, Inc., Promega Corporation, QIAGEN N.V., Quidel Corporation, R-Biopharm AG, RainSure Scientific, Roche Diagnostics Corporation, Solis BioDyne OU, STANDARD BIOTOOLS INC., Takara Bio USA, Inc., Thermo Fisher Scientific Inc., and Zymo Research Corp.
Market Segmentation & Coverage
1. Market Penetration: It presents comprehensive information on the market provided by key players.
2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.
3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.
4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.
5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.
1. What is the market size and forecast of the Digital PCR & Real-Time PCR Market?
2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the Digital PCR & Real-Time PCR Market?
3. What are the technology trends and regulatory frameworks in the Digital PCR & Real-Time PCR Market?
4. What is the market share of the leading vendors in the Digital PCR & Real-Time PCR Market?
5. Which modes and strategic moves are suitable for entering the Digital PCR & Real-Time PCR Market?
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