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局部止血剂市场:按产品、配方、应用和最终用途 - 全球预测 2024-2030Topical Hemostat Market by Product, Formulation, Application, End-Use - Global Forecast 2024-2030 |
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预计2023年外用止血剂市场规模为21.2亿美元,预计2024年将达22.6亿美元,2030年将达33.6亿美元,复合年增长率为6.80%。
外用止血剂是指用于促进止血的产品。当直接涂布伤口或手术部位时,它可以防止过度出血并促进血块形成。局部止血剂用于各种医疗环境,从急诊和外科手术到慢性伤口处理。外用止血剂含有促进人体自然凝血过程或提供物理屏障以帮助抑制血液的活性物质。由于人口老化和慢性病增加,全球手术数量增加推动了该市场的发展。然而,先进止血材料的高成本以及与使用某些止血材料相关的潜在併发症可能会限制其应用并限制其可用性。然而,能够模仿自然止血的合成和生物活性材料的开拓以及新兴市场止血剂开发中奈米技术的使用预计将为市场提供利润丰厚的机会。
主要市场统计 | |
---|---|
基准年[2023] | 21.2亿美元 |
预测年份 [2024] | 22.6亿美元 |
预测年份 [2030] | 33.6亿美元 |
复合年增长率(%) | 6.80% |
由于预防产品感染疾病等其他好处,外用止血剂的合併使用正在迅速增加。
基于胶原蛋白的局部止血剂源自于动物胶原蛋白,并透过提供促进凝块形成的基质来促进止血。胶原蛋白吸引并活化血小板,促进自然凝血连锁。这些产品型态多种形式,包括海绵、粉末和薄膜,用于各种手术环境中控制出血。组合局部止血剂结合了多种止血剂或机制以增强其有效性。它通常将胶原蛋白或明胶等物理基质与凝血酶和抗生素等促凝血物质结合以预防感染。此类多效产品同时提供控制出血和控制感染等其他益处,使其适合在手术领域更困难的出血情况下使用。明胶局部止血剂由猪或牛来源的明胶组成,通常呈现颗粒、发泡体或压缩海绵形式。这些止血材料提供了吸收血液并将凝血因子浓缩在出血部位的物理基质。明胶止血剂由于其有效性和易于使用而常用于手术和紧急情况。氧化再生纤维素基止血材料(外用止血剂)是透过对植物来源的纤维素进行化学处理而製成的,以提高其止血性能。这些产品提供凝血基质,降低伤口周围的 pH 值,并有助于止血过程。基于凝血酶的局部止血剂含有凝血酶,这是一种将纤维蛋白原转化为纤维蛋白的酶,诱导血块形成。这些止血剂由人类、牛或重组凝血酶製成,通常与其他材料(例如明胶或胶原蛋白垫片)结合使用。当手动压力不足或不切实际时,这种类型的止血剂对于控制出血特别有用。
配方:基质和凝胶止血材料越来越多地使用,因为它们能够适应不规则的伤口表面。
基质和凝胶止血剂是生物可吸收剂,其工作原理是提供支撑稳定血栓形成的物理支架。它们通常含有天然或合成物质,如胶原蛋白、明胶和纤维素。这些物质可与凝血酶和其他活性凝血剂结合,增强止血效果。粉状止血剂由颗粒状或绒毛状材料组成,黏附在伤口部位并透过脱水机制和凝血因子浓缩来帮助凝血。通常使用高岭土、沸石和其他矿物质等活性成分。它们特别有利,因为它们易于应用于出血表面,可用于微创手术,并且可以使用施用器或气腹进行应用。片状止血器和垫片止血器通常是止血材料的扁平结构,设计用于直接放置在出血组织表面上。常用的材料有氧化再生纤维素(ORC)、聚乙二醇(PEG)聚合物和胶原蛋白等。这些材料通常是优选的,因为它们易于处理,可以切割成所需的形状,并且适合提供促进凝块形成的机械屏障。海绵止血剂由明胶或胶原蛋白等可吸收材料製成,具有多孔结构,可为凝块形成提供机械支撑,并为血小板黏附和聚集提供基质。这些止血材料常用于各种外科手术,可应用于渗出表面或填充难以控制出血的空腔。
应用局部止血剂在心血管手术的重要用途
在心血管手术中,局部止血剂广泛用于控制血管吻合、移植部位和心臟组织的出血。它对于高风险患者的促进止血起着至关重要的作用,并且在准确的止血管理对于防止出血过多、血肿形成以及因出血而再次手术等併发症至关重要的情况下发挥着至关重要的作用。普通手术涉及多种手术,其中使用局部止血剂来控製手术部位的出血。这些药物可控製手术期间的出血,无论是开放性手术或腹腔镜手术。它可用于多种组织和器官,透过使手术野更加干燥,有望提高手术效果并缩短手术时间。肝臟和脾臟的撕裂通常会导致大量出血,因为这些器官是血管性的。在这种情况下,局部止血剂对于控制出血至关重要,可以快速止血以稳定患者的病情。整形外科手术,尤其是涉及关节关节重建和截骨术的手术,可能会导致大量出血。局部止血剂用于止血骨表面和软组织,可以减少术中出血,最大限度地减少术后瘀伤和血肿,并缩短癒合时间。在重组手术中,仔细止血对于确保移植物的活力和美观效果至关重要。局部止血剂可控制供体和受体部位的出血,最大限度地减少失血并降低术后併发症的风险,例如影响重组成功的血清肿和血肿形成。
最终用途:医院局部止血剂使用的演变
外用止血剂用于医院的各个科室,例如急诊室和手术室,特别是在心血管外科、整形外科和器官移植等高出血风险的手术中。在医院中,止血材料用于各种手术,从复杂手术到常规手术,因此通常需要稳定的止血材料供应,这使其成为製造商的重要市场。疗养院使用的局部止血剂主要用于需要小型手术或侵入性手术的老年族群。儘管疗养院的使用量远低于医院,但需要各种止血剂来适应因老龄化相关併发症而出血风险增加的患者。门诊手术中心是进行不需要住院的手术的专业设施。这些中心强调手术病例的效率和快速週转,通常需要速效局部止血剂来提高患者吞吐量并缩短手术时间。整容手术、微创手术等择期手术经常在这些中心进行,导致对止血材料的需求稳定。
区域洞察
在医疗基础设施、高人均医疗成本以及对先进外科手术的关注的支持下,美洲局部止血剂市场呈现强劲成长。此外,外科手术的普及和先进伤口管理推动的消费者需求正在推动市场成长,因为人们对局部止血剂的有效性的认识很高,并且医疗保健提供者准备采用新技术。最近的投资主要集中在美洲开发高度生物相容性和生物分解性的止血材料。欧盟 (EU) 拥有完善的医疗保健系统,强调病人安全和高标准护理,这推动了欧洲对局部止血剂的需求。大型製药公司的存在和对研究的大量投资为市场成长创造了有利的环境。同时,由于消费者对先进医疗产品的认识以及与医疗基础设施和私人医疗保健行业的开拓相关的需求不断增长,中东和非洲的市场正在扩大。这些地区的投资和倡议着重于建立医疗保健服务的能力,包括采用有效的手术辅助器具,例如外用止血剂。由于亚太地区人口众多、经济不断增长以及对医疗保健创新的投资,亚太地区代表了一个多元化且快速扩张的局部止血剂市场。此外,政府的支持和对医疗保健技术自给自足的关注正在推动市场成长,从而带动本地製造和创新的激增。亚太地区的最新专利反映出,考虑到经济和医疗保健服务的限制,开发适合当地市场的创新止血剂的措施。
FPNV定位矩阵
FPNV定位矩阵对于评估外用止血剂市场至关重要。我们检视与业务策略和产品满意度相关的关键指标,以对供应商进行全面评估。这种深入的分析使用户能够根据自己的要求做出明智的决策。根据评估,供应商被分为四个成功程度不同的像限:前沿(F)、探路者(P)、利基(N)和重要(V)。
市场占有率分析
市场占有率分析是一种综合工具,可以对局部止血剂市场供应商的现状进行深入而深入的研究。全面比较和分析供应商在整体收益、基本客群和其他关键指标方面的贡献,以便更好地了解公司的绩效及其在争夺市场占有率时面临的挑战。此外,该分析还提供了对该行业竞争特征的宝贵见解,包括在研究基准年观察到的累积、分散主导地位和合併特征等因素。详细程度的提高使供应商能够做出更明智的决策并制定有效的策略,从而在市场上获得竞争优势。
1. 市场渗透率:提供有关主要企业所服务的市场的全面资讯。
2. 市场开拓:我们深入研究利润丰厚的新兴市场,并分析其在成熟细分市场的渗透率。
3. 市场多元化:提供有关新产品发布、开拓地区、最新发展和投资的详细资讯。
4.竞争力评估及资讯:对主要企业的市场占有率、策略、产品、认证、监管状况、专利状况、製造能力等进行全面评估。
5. 产品开发与创新:提供对未来技术、研发活动和突破性产品开发的见解。
1.局部止血剂市场规模及预测是多少?
2.在外用止血剂市场的预测期间内,有哪些产品、细分市场、应用和领域需要考虑投资?
3.外用止血剂市场的技术趋势和法规结构是什么?
4.局部止血剂市场主要厂商的市场占有率是多少?
5. 进入局部止血剂市场的合适型态和策略手段是什么?
[184 Pages Report] The Topical Hemostat Market size was estimated at USD 2.12 billion in 2023 and expected to reach USD 2.26 billion in 2024, at a CAGR 6.80% to reach USD 3.36 billion by 2030.
A topical hemostat refers to products used to promote hemostasis, a process of stopping bleeding. It is applied directly to a wound or surgical site to prevent excessive blood loss and to encourage clot formation. Topical hemostats are used in various medical situations, from emergency settings and surgical procedures to managing chronic wounds. Topical hemostats contain active substances that accelerate the body's natural clotting process or provide a physical barrier to assist with blood containment. A global rise in surgeries due to an aging population and the elevating incidences of chronic diseases is driving the market. However, the high cost of advanced hemostats and potential complications associated with using certain hemostatic agents can restrict their application and limit their accessibility. Nevertheless, the development of synthetic and bioactive materials that can mimic natural hemostasis and the utilization of nanotechnology in developing advanced hemostatic agents are expected to create lucrative opportunities for the topical hemostat market.
KEY MARKET STATISTICS | |
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Base Year [2023] | USD 2.12 billion |
Estimated Year [2024] | USD 2.26 billion |
Forecast Year [2030] | USD 3.36 billion |
CAGR (%) | 6.80% |
Product: Burgeoning adoption of combination topical hemostats owing to the additional benefits such as infection reduction
Collagen-based topical hemostats are derived from animal collagen, which promotes hemostasis by providing a matrix that facilitates clot formation. Collagen attracts and activates platelets, enhancing the natural coagulation cascade. These products, such as sponges, powders, or films, can come in various forms and are used in different surgical scenarios to control bleeding. Combination topical hemostats incorporate multiple hemostatic agents or mechanisms to enhance their efficacy. They often combine a physical matrix, such as collagen or gelatin, with a procoagulant substance like thrombin or an antibiotic agent to prevent infection. These multi-action products provide simultaneous bleeding control and additional benefits such as infection reduction and are suitable for use in more challenging bleeding situations in surgical settings. Gelatin-based topical hemostats consist of porcine or bovine-derived gelatin and often come as granules, foams, or compressed sponges. These hemostats provide a physical matrix that can absorb blood and concentrate clotting factors at the bleeding site. Gelatin-based hemostats are commonly used in surgical and emergency settings due to their efficacy and ease of application. Oxidized regenerated cellulose-based topical hemostats are made from plant-derived cellulose that is chemically treated to improve its hemostatic properties. These products provide a matrix for clotting and lowering the pH around the wound, which assists in the hemostasis process. Thrombin-based topical hemostats contain thrombin, an enzyme that converts fibrinogen to fibrin, thereby inducing clot formation. These hemostats can be made from human, bovine, or recombinant thrombin and are often applied in conjunction with other materials, including gelatin or collagen pads. This category of hemostatic agent is particularly useful in controlling bleeding when the application of manual pressure is insufficient or impractical.
Formulation: Proliferating utilization of matrix and gel hemostats owing to their ability to conform to irregular wound surfaces
Matrix and gel hemostats are bioresorbable agents that work on the principle of providing a physical scaffold to assist in the formation of a stable blood clot. They often contain natural or synthetic substances such as collagen, gelatin, or cellulose. These materials can be combined with thrombin or other active clotting agents to enhance hemostasis. Powder hemostats comprise granular or fluffy materials that adhere to the wound site and assist in clotting through dehydration mechanisms and concentration of clotting factors. Active ingredients such as kaolin, zeolite, or other mineral substances are commonly used. They are particularly advantageous for their ease of application on bleeding surfaces, their usefulness in minimally invasive procedures, and their ability to be applied using applicators or insufflators. Sheet and pad hemostats are usually flat configurations of hemostatic materials designed to be placed directly onto bleeding tissue surfaces. Materials such as oxidized regenerated cellulose (ORC), polyethylene glycol (PEG) polymers, and collagen are commonly used in these formats. They are often preferred for their ease of handling, ability to cut to required shapes, and suitability for providing a mechanical barrier that facilitates clot formation. Sponge hemostats are made from absorbable materials such as gelatin or collagen, which have a porous structure that provides mechanical support for clot formation and a matrix for platelet adhesion and aggregation. These hemostats are commonly used in various surgical procedures and can be applied to oozing surfaces or fill cavities where controlling bleeding is challenging.
Application: Significant usage of topical hemostats in cardiovascular surgery
In cardiovascular surgery, topical hemostats are extensively used to manage bleeding from vascular anastomoses, graft sites, and heart tissues. They are pivotal in promoting hemostasis in high-risk patients or scenarios where precise hemostatic control is critical to prevent excessive blood loss and potential complications such as hematoma formation or reoperation due to bleeding. General surgery involves various procedures where topical hemostats are applied to control bleeding from the surgical site. Whether in open or laparoscopic procedures, these agents reduce intraoperative bleeding. They can be used on various tissues and organs to ensure a drier operative field, which may improve surgical outcomes and shorten operative times. Liver and spleen lacerations often result in significant bleeding due to the vascular nature of these organs. Topical hemostats are crucial in managing bleeding in such cases, providing rapid hemostasis for patient stability. Orthopedic surgeries, particularly those involving joint replacements or bone cutting, can cause significant bleeding. Topical hemostats are used to provide hemostasis at bone surfaces and soft tissue, reducing intraoperative bleeding and potentially minimizing postoperative bruising, hematoma, and improving healing time. In reconstructive surgery, achieving meticulous hemostasis is critical to ensure graft viability and aesthetic outcomes. Topical hemostats are utilized to manage bleeding from both donor and recipient sites, minimizing blood loss and mitigating the risk of postoperative complications such as seroma or hematoma formation, which could compromise the success of the reconstruction.
End-Use: Evolving utilization of topical hemostats in hospitals
Topical hemostats are utilized across various departments of hospitals, such as emergency wards and operating theatres, especially in surgeries involving high bleeding risks, such as cardiovascular, orthopedic, and organ transplantations. Hospitals often require a consistent supply of hemostats due to their broad service in complex and routine surgeries, making them a critical market for manufacturers. Nursing homes adopt topical hemostats, focusing mainly on the geriatric population that may require minor surgical or invasive procedures. Although the volume of use in nursing homes is significantly lower than in hospitals, they still need an array of hemostatic agents to cater to patients who may have heightened bleeding risks due to age-related comorbid conditions. Ambulatory surgical centers, or outpatient surgical centers, are specialized facilities where surgeries that do not require hospital admission. These centers value efficiency and the rapid turnover of surgical cases, often looking for fast-acting topical hemostats to enhance patient throughput and reduce procedure times. The frequency of elective surgeries, such as cosmetic and minimally invasive procedures, at these centers contributes to a steady demand for hemostatic products.
Regional Insights
The Americas exhibit robust growth in the topical hemostat market supported by healthcare infrastructure, high per capita healthcare expenditure, and a focus on advanced surgical procedures. Furthermore, the consumer need, due to the prevalence of surgical procedures and advanced wound management practices with high awareness of the effectiveness of topical hemostats and the readiness of healthcare providers to adopt new technologies, bolster the market growth. Recent investments are primarily channeled toward developing advanced biocompatible and biodegradable hemostats in the Americas. The European Union boasts a sophisticated healthcare system with a strong emphasis on patient safety and high standards of care, which drives the demand for topical hemostats in Europe. The presence of major pharmaceutical companies, coupled with significant investments in research, creates a favorable environment for market growth. On the other hand, in the Middle East and Africa, the market is growing owing to consumers' awareness of advanced medical products and rising demand linked to the development of healthcare infrastructure and the private healthcare sector. Investments and initiatives in these regions focus on capacity building in healthcare services, including adopting effective surgical aids such as topical hemostats. The Asia Pacific region presents a diverse and rapidly expanding topical hemostat market owing to its sizeable populations, growing economies, and investment in healthcare innovation. Furthermore, government backing and a focus on self-sufficiency in healthcare technologies have spurred market growth, leading to a surge in local manufacturing and innovation. The latest patents in the APAC region reflect a drive towards developing innovative hemostatic agents suitable for the local market, considering the economic and healthcare delivery constraints.
FPNV Positioning Matrix
The FPNV Positioning Matrix is pivotal in evaluating the Topical Hemostat Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).
Market Share Analysis
The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the Topical Hemostat Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.
Key Company Profiles
The report delves into recent significant developments in the Topical Hemostat Market, highlighting leading vendors and their innovative profiles. These include Aegis Lifesciences Private Limited, Axio Biosolutions Pvt Ltd, B.Braun Melsungen AG, Baxter International, Inc., Becton, Dickinson and Company, Betatech Medical, BioCer Entwicklungs-GmbH, Bristol-Myers Squibb Company, Dilon Technologies Inc, GELITA MEDICAL GmbH, Hemostasis, LLC, Integra LifeSciences Corporation, Johnson & Johnson Services, Inc., Marine Polymer Technologies, Inc., Medline Industries, LP, Medtrade Products Ltd, Medtronic PLC, Meril Life Sciences Pvt. Ltd, Pfizer Inc., Southmedic Inc., Stryker Corporation, SYMATESE SAS, Takeda Pharmaceutical Company Limited, Teleflex Incorporated, and Zeria Pharmaceutical Co., Ltd..
Market Segmentation & Coverage
1. Market Penetration: It presents comprehensive information on the market provided by key players.
2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.
3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.
4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.
5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.
1. What is the market size and forecast of the Topical Hemostat Market?
2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the Topical Hemostat Market?
3. What are the technology trends and regulatory frameworks in the Topical Hemostat Market?
4. What is the market share of the leading vendors in the Topical Hemostat Market?
5. Which modes and strategic moves are suitable for entering the Topical Hemostat Market?