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市场调查报告书
商品编码
1497775
碱基编辑市场:按组件、类型、技术、应用和最终用途划分 - 2024-2030 年全球预测Base Editing Market by Component (Consumables, Services), Type (DNA Base Editing, RNA Base Editing), Technique, Application, End-use - Global Forecast 2024-2030 |
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基础编辑市场规模预计2023年为2.7765亿美元,2024年达到3.1993亿美元,预计2030年将达到7.8547亿美元,复合年增长率为16.01%。
碱基编辑是一种精确基因组编辑技术,可在基因组的特定位置将一个 DNA 碱基对直接不可逆地改变为另一个碱基对,无需双链DNA 断裂或供体DNA 模板即可转换为.这种创新方法使用融合蛋白,将非催化作用CRISPR-Cas9 与碱基脱氨酶结合。透过以嚮导 RNA 靶向所需的基因组位点,碱基编辑酶透过化学修饰 DNA 碱基来诱导点突变,从而在 DNA 复製后导致碱基对替换。该技术在治疗性基因编辑、疾病遗传学研究和新农产品开发方面具有潜在应用。该市场包括碱基编辑工具、服务、消耗品的开发和销售,以及治疗开发、农业和生物技术研究中的各种应用。低音编辑具有广泛的用途。在治疗领域,碱基编辑用于纠正导致遗传疾病的单点突变。在农业中,碱基编辑可以开发具有抗病性和增加产量等有益特性的作物。在研究和开发中,它是了解基因功能和创建人类疾病模型的宝贵工具。碱基编辑的市场开拓包括开发基因疗法的製药公司、农业生物技术公司和学术研究机构。影响碱基编辑成长的关键因素包括政府资助的增加、对基因组研究的更多关注、扩大基因组在製药领域的应用以及罕见疾病盛行率的增加。此外,生物技术公司和研究机构之间的策略联盟正在推动市场扩张。然而,碱基编辑市场面临一些限制和挑战,包括伦理和安全问题以及有关碱基编辑的严格法规。另一方面,碱基编辑在农业领域的不断扩大应用以及全球范围内对个人化医疗日益增长的偏好为碱基编辑的扩展提供了机会。
主要市场统计 | |
---|---|
基准年[2023] | 27765万美元 |
预测年份 [2024] | 31993万美元 |
预测年份 [2030] | 7.8547 亿美元 |
复合年增长率(%) | 16.01% |
区域洞察
在北美,美国和加拿大处于碱基编辑研究和应用的前沿,大型生物技术公司的存在、对基因编辑技术的大量投资以及有利的法规环境有助于碱基编辑的快速普及。学术机构和生物技术公司之间的合作正在刺激创新,重点是治疗遗传疾病的治疗应用。在南美洲,人们对碱基编辑越来越感兴趣,特别是在农业和作物改良领域。巴西和阿根廷等国家正在利用碱基编辑来提高作物的復原力和生产力,并投资生物技术来加强其庞大的农业部门。由于基因研究的增加和生物技术投资的增加,亚太地区的碱基编辑市场正在经历显着成长。中国、日本等国家走在前列,其中中国在研究成果和专利技术方面处于领先地位。尤其是中国,因其在基因编辑方面取得的显着进展而成为热门话题,并积极将碱基编辑引入临床研究。日本以其健全的法律规范而闻名,该框架平衡了技术创新和道德考虑。欧洲拥有强大的製药工业和强大的研究环境,这正在推动碱基编辑技术的采用。一些欧洲国家正在该领域做出重大贡献,欧盟(EU)透过各种财政援助积极支持基因编辑研究。随着中东地区,特别是沙乌地阿拉伯和阿拉伯联合大公国等国家对医疗创新的投资增加,碱基编辑正成为医学研究和潜在治疗的工具。在非洲,科技仍在发展,有望解决医疗保健和农业领域的重要挑战。透过国际伙伴关係和教育措施进行能力建设对于扩大该地区的碱基编辑至关重要。
FPNV定位矩阵
FPNV 定位矩阵对于评估供应商在基础编辑市场的定位至关重要。此矩阵提供了对供应商的全面评估,并检验了与业务策略和产品满意度相关的关键指标。这种详细的评估使用户能够根据自己的要求做出明智的决定。根据评估结果,供应商被分为代表其成功程度的四个像限:前沿(F)、探路者(P)、利基(N)和重要(V)。
市场占有率分析
市场占有率分析是一个综合工具,可以对基础编辑市场中供应商的当前状态进行深入而详细的评估。透过仔细比较和分析供应商的贡献,您可以更深入地了解每个供应商的绩效以及他们在争夺市场占有率时面临的挑战。这些贡献包括整体收益、客户群和其他重要指标。此外,该分析还提供了对该行业竞争性质的宝贵见解,包括在研究基准年期间观察到的累积、分散主导地位和合併特征等因素。有了这些详细信息,供应商可以做出更明智的决策并製定有效的策略,以在市场竞争中保持领先地位。
策略分析与建议
策略分析对于寻求在全球市场站稳脚跟的组织至关重要。对目前在基础编辑市场中的地位进行全面评估,使公司能够做出符合其长期愿望的明智决策。此关键评估涉及对组织的资源、能力和整体绩效进行彻底分析,以确定核心优势和需要改进的领域。
[183 Pages Report] The Base Editing Market size was estimated at USD 277.65 million in 2023 and expected to reach USD 319.93 million in 2024, at a CAGR 16.01% to reach USD 785.47 million by 2030.
Base Editing is a form of precision genome editing technique that enables the direct, irreversible conversion of one DNA base pair into another at a specific location in the genome without requiring a double-stranded DNA break or a donor DNA template. This innovative approach uses a fusion protein consisting of a catalytically disabled CRISPR-Cas9 linked to a base deaminase enzyme. By targeting the desired genomic loci with guide RNA, base editors can induce point mutations by chemically modifying the DNA bases, leading to a base pair substitution after DNA replication. This technique offers potential applications in therapeutic gene editing, research on disease genetics, and the development of new agricultural products. This market includes the development and sales of base editing tools, services, consumables, and various applications in therapeutic development, agriculture, and biotechnology research. The applications of base editing are vast and varied. In the therapeutic space, base editing is used to correct single-point mutations that cause genetic diseases. Base editing can develop crops with beneficial traits such as disease resistance or increased yield in agriculture. For research and development, it is an invaluable tool for understanding gene function and creating models of human disease. The market scope for base editing includes pharmaceutical companies developing gene therapies, agricultural biotechnology firms, and academic and research institutions. Key factors influencing the growth of base editing include rising government funding and growing focus on genomic studies, expanding the application of genomics in the pharmaceutical sector, and increasing prevalence of rare diseases. Additionally, strategic collaborations among biotech firms and research organizations fuel market expansion. However, the base editing market faces several limitations and challenges, such as issues associated with ethics and safety and stringent regulations regarding base editing. On the other hand, the expanding application of base editing in the agricultural sector and increasing preference for personalized medicine worldwide present opportunities for expanding base editing.
KEY MARKET STATISTICS | |
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Base Year [2023] | USD 277.65 million |
Estimated Year [2024] | USD 319.93 million |
Forecast Year [2030] | USD 785.47 million |
CAGR (%) | 16.01% |
Regional Insights
In North America, the United States and Canada are at the forefront of base editing research and applications, with the presence of major biotechnology companies, heavy investments in gene editing technologies, and a favorable regulatory environment contributing to the rapid adoption of base editing. Partnerships between academic institutions and biotech firms are fueling innovation, with an emphasis on therapeutic applications to treat genetic disorders. South America has shown an increased interest in base editing, particularly in the areas of agriculture and crop improvement. Countries such as Brazil and Argentina are investing in biotechnology to bolster their vast agricultural sectors, using base editing to enhance crop resilience and productivity. The APAC region is experiencing substantial growth in the base editing market due to the rise in genetic research and increased investments in biotechnology. Countries such as China and Japan are at the forefront, with China leading in research output and patented technologies. China, in particular, has made headlines with significant advancements in gene editing and is actively implementing base editing in clinical research. Japan is notable for its precise regulatory framework, which balances innovation with ethical considerations. Europe boasts a strong pharmaceutical industry and a robust research environment, which propels the adoption of base editing technology. With the European Union's active support for gene editing research through various funding initiatives, several European countries are making notable contributions to the field. The Middle East has seen increased investment in healthcare innovation, particularly in nations such as Saudi Arabia and the United Arab Emirates, where base editing is emerging as a tool for medical research and potential treatments. In Africa, while the technology is still developing, it has the prospect of addressing critical challenges in healthcare and agriculture. Capacity building through international partnerships and educational initiatives is essential for the expansion of base editing in the region.
Market Insights
The market dynamics represent an ever-changing landscape of the Base Editing Market by providing actionable insights into factors, including supply and demand levels. Accounting for these factors helps design strategies, make investments, and formulate developments to capitalize on future opportunities. In addition, these factors assist in avoiding potential pitfalls related to political, geographical, technical, social, and economic conditions, highlighting consumer behaviors and influencing manufacturing costs and purchasing decisions.
FPNV Positioning Matrix
The FPNV positioning matrix is essential in evaluating the market positioning of the vendors in the Base Editing Market. This matrix offers a comprehensive assessment of vendors, examining critical metrics related to business strategy and product satisfaction. This in-depth assessment empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success, namely Forefront (F), Pathfinder (P), Niche (N), or Vital (V).
Market Share Analysis
The market share analysis is a comprehensive tool that provides an insightful and in-depth assessment of the current state of vendors in the Base Editing Market. By meticulously comparing and analyzing vendor contributions, companies are offered a greater understanding of their performance and the challenges they face when competing for market share. These contributions include overall revenue, customer base, and other vital metrics. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With these illustrative details, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.
Recent Developments
Beam Announces Agreement for Lilly to Acquire Beam's Opt-In Rights to Verve Therapeutics' Base Editing Programs for Cardiovascular Disease
Beam Therapeutics Inc., a prominent provider in base editing technology, has crafted a strategic alliance with Eli Lilly and Company, a pharmaceutical company. Lilly is expected to acquire rights from Beam's updated agreement with Verve Therapeutics, Inc., taking a significant step forward with co-development and co-commercialization options for programs targeting key cardiovascular disease markers like PCSK9 and ANGPTL3-plus an undisclosed target. [Published On: 2023-10-31]
Revvity Expands Access to Base Editing Technology With Aim to Accelerate Discovery to Cure
Revvity Inc. has launched its state-of-the-art Pin-point base editing platform reagents, heralding a new era in CRISPR gene editing technology for preclinical research researchers. With the ability to carry out precision single base changes across various genomic sites, Revvity's Pin-point platform enhances functional genomics, aiding in the optimization of drug development and the simplification of cell line and cell therapy production. [Published On: 2023-09-26]
Researchers develop new base editing tools using AI-predicted protein structure clustering
The research team at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, has significantly advanced the field of base editing with their groundbreaking use of artificial intelligence. By leveraging the AlphaFold2 platform to predict and classify structures of deaminase proteins, they have made strides in identifying novel enzymes with unique functions. These enzymes have paved the way for the innovation of custom genetic traits in plants, addressing previous limitations in gene editing due to sequence specificity and organism compatibility. Their research led to the development of various new base editors, which exhibit enhanced efficiencies, minimized off-target effects, and are adaptable to preferred sequence contexts. [Published On: 2023-06-27]
Strategy Analysis & Recommendation
The strategic analysis is essential for organizations seeking a solid foothold in the global marketplace. Companies are better positioned to make informed decisions that align with their long-term aspirations by thoroughly evaluating their current standing in the Base Editing Market. This critical assessment involves a thorough analysis of the organization's resources, capabilities, and overall performance to identify its core strengths and areas for improvement.
Key Company Profiles
The report delves into recent significant developments in the Base Editing Market, highlighting leading vendors and their innovative profiles. These include Addgene, Inc., Beam Therapeutics, Beijing Qi Biodesign Biotechnology Company Limited, Bio Palette Co., Ltd., Creative Biogene, DH Life Sciences, LLC, Editas Medicine, Inc., ElevateBio, LLC, GenScript Biotech Corporation, Intellia Therapeutics, Inc., KromaTiD Inc., Pairwise Plants Services, ProQR Therapeutics N.V., QIAGEN GmbH, Revvity, Inc., Sangamo Therapeutics, Inc., Synthego Corporation, Tecan Group, and TriLink BioTechnologies by Maravai LifeSciences.
Market Segmentation & Coverage