市场调查报告书
商品编码
1261662
2022-2028年按产品,应用(Western Blotting,Southern Blotting,Northern Blotting 等)、最终用户、地区展望和预测分列的全球转移膜市场规模、份额、行业趋势分析报告Global Transfer Membrane Market Size, Share & Industry Trends Analysis Report By Product, By Application (Western Blotting, Southern Blotting, Northern Blotting and Others), By End-User, By Regional Outlook and Forecast, 2022 - 2028 |
转移膜市场规模预计到 2028 年将达到 4.189 亿美元,预测期内復合年增长率为 4.7%。
印迹是一种将蛋白质和核酸固定在固体基质(通常是尼龙或硝酸纤维素膜)上的方法。 杂交研究的主要技术是核酸印迹。 研究基因表达、组织等的各种实验方法都是基于核酸在膜上的标记和杂交。
在血液等复杂的生物混合物中,特定蛋白质的鑑定和定量一直是科学和医学的重要目标。 近年来,检测基因组DNA中的异常基因在临床研究和遗传咨询中越来越重要。 通过印迹方法检测不同的蛋白质和核酸序列。 因此,作为分子生物学和临床研究不可或缺的设备,研究和开发正在取得进展。
COVID-19 影响分析
大流行对全球经济产生了不利影响,许多市场在封锁限制的重压下崩溃。 由于研发项目被关闭,大流行也打击了转印膜业务。 冠状病毒疫苗的研发使转移膜市场保持活力。 然而,在疫情初期,市场的增长趋势出现了下行趋势。
市场增长因素
遗传和传染病的增加
虽然最近进行了一些积极的尝试,但政府通常不会强调对遗传病和先天缺陷(EMR)的控制。 有一种严重的误解,认为这些问题很少见且无法控制。 据世界卫生组织称,约有 2% 至 5% 的出生婴儿受到遗传病和先天缺陷的影响,它们占发达国家儿科住院人数的 30% 和婴儿死亡人数的 50% 以上。 与流行观点相反,先天性和遗传性疾病在该地区至少与发达国家一样普遍。
对基于 RNA 的药物的需求不断增长
生物治疗学发展最快的领域之一是 RNA 疗法。 这些疗法建立在强大且适应性强的基础上,具有几乎无限的可能性来满足未满足的临床需求。 RNA 疗法将改变许多疾病的护理标准。 越来越多的 RNA 疗法正在研究和临床研究中。 RNA 疗法的快速扩张归功于解决了递送、免疫原性和稳定性问题。 每个领域都有进一步发展和发明的潜力,但到 RNA 疗法投入实际使用时,解决方案已经演变。
市场约束
有多种可供选择的印迹方法
在光谱等聚焦和毛细管等聚焦中,蛋白质按等电点而不是大小分类。 也就是说,在凝胶上形成一个 pH 梯度,这样当蛋白质达到与其 pI 相对应的 pH 值时,它们就会停止迁移。 该方法具有分辨率高、样品分析快速、样品保存方便等优点。 因此,其他选择的存在与否及其优势预计会阻碍转移膜市场的扩张。
产品概览
根据产品,转移膜市场分为 PVDF、硝化纤维和尼龙。 PDVF 细分市场以 2021 年最大的收入份额主导转移膜市场。 这是因为它提供了一种高度可靠且化学惰性的替代其他膜的方法。 PVDF 转移膜允许更简单的蛋白质剥离和重新检测。 该膜的疏水结构使其能够与蛋白质强烈相互作用,增强蛋白质结合併促进有效运输。 由于PVDF膜的优势,其产品被广泛使用,推动了该细分市场的增长。
交通方式展望
转印膜市场根据转印方式分为湿式或槽式转印、半干式电印迹(半干式转印)、干式电印迹(干式转印)等。 在 2021 年的转印膜市场中,半干式电印迹(半干式转印)细分市场占据了相当大的收入份额。 这是因为该技术使用水平盒组件,该组件由浸有转移缓衝液的过滤器、预湿膜、滤纸和凝胶组成。 这种方法是有益的,因为它使用少量的转移缓衝液,并允许在室温下将蛋白质快速转移到膜上。
样本类型
按样品类型,转印膜市场分为蛋白质印迹、Southern 印迹、Northern 印蹟等。 Western blotting 部分在 2021 年的转移膜市场中占据了最大的收入份额。 这是由于这种方法广泛用于临床和诊断测试。 蛋白鑑定的高灵敏度和特异性是Western blotting作为分析工具的两大优势。 此外,该方法可以在超过 300,000 种蛋白质中准确识别单一目标蛋白质,极大地促进了其在探索性研究应用中的使用。
最终用户视角
根据最终用户,转移膜市场分为生物製药和製药公司、学术和研究机构以及诊断实验室。 2021 年,学术和研究机构部门在转移膜市场中占据了重要的收入份额。 这是由于发达国家政府的大力支持和大量研究成果的现成可用性。 此外,随着印迹方法在知名学术机构中的日益普及,预计未来几年转印膜的收入前景将有所增加。
区域展望
按地区划分,分析了北美、欧洲、亚太地区和 LAMEA 的转印膜市场。 北美地区将在 2021 年占据转移膜市场的最高收入份额。 这是由于研发活动的数量、新药开发的大量财政支出以及公共和商业机构为研究提供的支持。 此外,该地区慢性病和特殊疾病高发,预计将促进该地区的发展。 预计这些因素将影响预测期内转移膜市场的扩张。
The Global Transfer Membrane Market size is expected to reach $418.9 Million by 2028, rising at a market growth of 4.7% CAGR during the forecast period.
The term "transfer membrane" describes a group of systems that control how ions and other solutes travel across biological membranes composed of lipid bilayers with embedded proteins. Proteins must be moved from the gel onto a suitable membrane for antibody staining and detection when electrophoresis is finished. The transfer is accomplished by running a current from the gel to the membrane. Transfer membrane has many benefits, including improved staining properties, the ability to be tested repeatedly, and compatibility with a range of detection chemistries, such as radioactive, chromogenic, chemiluminescent, fluorescent, and chemifluorescent methods.
Transfer membranes are the solid phase support employed in blotting procedures to transfer proteins or nucleic acids from gel matrices for detection and analysis. Proteins or nucleic acids are immobilized on a solid matrix membrane after size separation by electrophoresis in a polyacrylamide or agarose gel. This makes it easier to identify certain proteins or nucleic acids using antibodies specific to the target of interest.
Blotting is a method for immobilizing proteins or nucleic acids on a solid substrate, often nylon or nitrocellulose membranes. The primary methodology for hybridization research is nucleic acid blotting. Various experimental approaches to investigate gene expression, organization, etc., are based on the labeling and hybridization of nucleic acids on membranes.
With complicated biological mixes like blood, identifying and quantifying particular proteins has long been a crucial objective in science and medical practice. In recent years, clinical research and genetic counseling have increasingly emphasized the detection of aberrant genes in genomic DNA. Protein and nucleic acid sequences that are distinct are found using blotting methods. They have evolved into crucial molecular biology and clinical research instruments due to their development into susceptible and specialized devices.
COVID-19 Impact Analysis
The international economy was negatively impacted by the pandemic, which led to numerous markets collapsing under the weight of lockdown regulations. As a result of lockdown regulations, numerous research and development projects were halted during the COVID-19 pandemic, which harmed the transfer membrane business. The transfer membrane market was kept alive by research on creating coronavirus vaccines. Still, the market witnessed a downward growth trend in the initial phase of the pandemic.
Market Growth Factors
Increasing prevalence of hereditary and infectious disorders
Despite some recent positive attempts, governments typically do not emphasize controlling genetic illnesses and congenital anomalies (EMR). There are severe misunderstandings that these problems are uncommon and cannot be controlled. According to WHO, around 2% to 5% of all live births are affected by genetic illnesses and congenital anomalies, accounting for up to 30% of pediatric hospital admissions and over 50% of infant fatalities in developed nations. Contrary to popular opinion, congenital and genetic illnesses are at least as prevalent in the area as in more developed parts of the world.
Growing need for RNA-based medicines
A fast-developing area of biotherapeutics is RNA Therapeutics. These treatments are built on a strong, adaptable foundation that offers almost limitless potential to meet unmet clinical requirements. The standard of treatment for numerous illnesses will alter due to RNA Therapeutics. There are an increasing number of RNA medications under research and clinical studies. The fast expansion of RNA treatments results from the issues with delivery, immunogenicity, and stability being resolved. While each area has potential for additional development and invention, the solutions have evolved to the point where RNA Therapies are now practicable.
Market Restraining Factors
Availability of a variety of blotting method substitutes
Spectroscopic isofocusing, proteins are sorted by isoelectric point rather than by size in capillary isofocusing. In other words, the protein will cease migrating when it reaches the pH corresponding to its pI since a pH gradient has been generated throughout the gel. This approach has the advantages of greater resolution, quicker sample analysis, and sample preservation. That is why, the availability of the other alternatives and their advantages are expected to hinder the market expansion of the transfer membrane.
Product Outlook
Based on product, the transfer membrane market is segmented into PVDF, nitrocellulose and nylon. The PDVF segment dominated the transfer membrane market with maximum revenue share in 2021. This is because it provides a very reliable and chemically inert alternative to other membranes. PVDF transfer membranes make it simpler to strip and re-probe proteins. These membranes' hydrophobic structure allows them to interact strongly with proteins, enhancing protein binding and facilitating effective transport. Because of PVDF transfer membranes' benefits, their goods are widely used, which aids in boosting the segment's growth.
Transfer Method Outlook
On the basis of transfer method, the transfer membrane market is divided into wet or tank transfer, semi-dry electro blotting (semi-dry transfer), dry electro blotting (dry transfer) and others. The semi-dry electro blotting (semi-dry transfer) segment procured a substantial revenue share in the transfer membrane market in 2021. This is because this technique uses horizontal cassette assemblies, which are made up of transfer buffer-soaked filters, pre-wetted membranes, filter paper, and gel. The approach is beneficial since it uses less transfer buffer and can swiftly transfer proteins to membranes at room temperature.
Sample Type Outlook
By sample type, the transfer membrane market is classified into western blotting, southern blotting, northern blotting and others. The western blotting segment witnessed the largest revenue share in the transfer membrane market in 2021. This is due to the widespread use of the method for clinical and diagnostic tests. High sensitivity and specificity for protein identification are two benefits of western blotting that make it useful as an analytical tool. Moreover, the method can precisely identify a single target protein among more than 300,000 other proteins, considerably enhancing its use in exploratory research applications.
End User Outlook
Based on the end-user, the transfer membrane market is bifurcated into biopharmaceutical & pharmaceutical companies, academic & research institutes and diagnostic labs. The academic & research institutes segment recorded a significant revenue share in the transfer membrane market in 2021. This is due to the robust government backing and extensive research findings readily accessible in industrialized nations. In addition, the growing penetration of blotting methods among reputable academic research institutes is anticipated to increase the prospects for transfer membranes to generate income in the following years.
Regional Outlook
Region-wise, the transfer membrane market is analyzed across North America, Europe, Asia Pacific, and LAMEA. The North America region generated the highest revenue share in the transfer membrane market in 2021. This is owing to the volume of R & D activities, major financial expenditures made in developing new pharmaceuticals, and support provided by both public and commercial entities for research. Moreover, the increased incidence of chronic illnesses and specific diseases in the area is projected to boost the region's development. These factors are anticipated to impact the transfer membrane market's expansion in the projected period.
The market research report covers the analysis of key stake holders of the market. Key companies profiled in the report include Thermo Fisher Scientific, Inc., Danaher Corporation, Bio-Rad Laboratories, Inc., Merck KGaA, PerkinElmer, Inc., Abcam Plc, Santa Cruz Biotechnology, Inc., ATTO Corporation, Azure Biosystems, Inc., and GVS S.p.A.
Strategies Deployed in Transfer Membrane Market
Oct-2022: Thermo Fisher Scientific revealed Gibco CTS DynaCellect magnetic separation system. The system features cell isolation, activation and depletion. DynaCellect separate the right cells and minimize failures in manufacturing. The launch is aimed at providing a scalable, flexible, automated and closed system for cell therapy manufacturing.
Jan-2022: Thermo Fisher completed its acquisition of PeproTech, a recombinant proteins provider. With this acquisition, the company aimed to expand its capabilities in order to meet the rising demand for gene therapy and the growth of the cell market. In addition, this acquisition would also complement the cell culture media products of Thermo Fisher through the addition of applications. PeproTech's recombinant proteins offering, which would allow Thermo Fisher to offer substantial benefits to its customers via an integrated portfolio.
Jun-2021: Danaher completed the acquisition of Aldevron, a US-based biotech business. With this acquisition, Danaher would expand its abilities into the crucial field of genomic medicine and help consumers and their essential task to obtain more life-saving treatments and vaccines to market quickly.
May-2021: PerkinElmer took over Nexcelom Bioscience, a Massachusetts-based biotechnology company. Under this acquisition, the integration would broaden PerkinElmer's efforts to support the government, academic, and biopharmaceutical organizations in developing their comprehensive workflows and help efforts to boost time to market and time to target other beneficial therapies.
Jul-2020: Merc expanded its footprint by opening a lab in Shanghai. M Lab Collaboration Center provides customizable solutions made for the Life Science community in China to help advance drug development.
Apr-2020: Bio-Rad Laboratories took over Celsee, an instruments and consumables provider. With this acquisition, the company aimed to expand its reach throughout the world in order to meet the rising demands of customers for single-cell analysis and precision medicine in order to offer improved insight into the disease along with its diagnosis as well as treatment.
Feb-2018: PerkinElmer, Inc. took over RHS Limited, develops and markets biotechnology technologies. Through this acquisition, the company aimed to expand its genomic research offerings.
Market Segments covered in the Report:
By Product
By Transfer Method
By Application
By End-User
By Geography
Companies Profiled
Unique Offerings from KBV Research
List of Figures