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空间基因组学和转录组学市场：2023 年至 2028 年预测
市场调查报告书
商品编码
1410098

空间基因组学和转录组学市场：2023 年至 2028 年预测

Spatial Genomics and Transcriptomics Market - Forecasts from 2023 to 2028
出版日期: | 出版商: Knowledge Sourcing Intelligence | 英文 150 Pages | 商品交期: 最快1-2个工作天内

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简介目录

空间基因组学和转录组学市场预计在预测期内将以 17.38% 的复合年增长率成长。

空间基因组学和转录组学是指应用最尖端科技来帮助分析和视觉化基因表现模式。由于对精准医学的需求不断增长以及单细胞分析的进步，空间基因组学和转录组学市场正在显着扩大。这些技术在许多领域具有巨大的潜力，因为它们同时提供了对组织内基因和遗传物质的空间组织的洞察。这些技术将帮助癌症研究破解肿瘤微环境的复杂性和异质性，指导有针对性的治疗方法和诊断的创建。

空间基因组学和转录组学市场的成长动力

在药物研发和开发中，对空间基因组学和转录组学市场的需求不断增长。空间基因组学和转录组学越来越多地用于药物研发发现和开发。这种需求的重点最近从研究转向药物研发发现和开发，尤其是对癌症和神经系统疾病等疾病的需求不断增加。随着第四代定序仪的出现以及空间基因组分析作为癌症诊断工具的潜力不断增加，空间基因组学和转录组学市场预计将变得更加活跃。

增加基因组学/转录组学应用的研究

来自学术机构的研究人员是影响基因组学和转录组学市场成长的关键因素。例如，费城儿童医院等研究中心在学术和生物技术环境中拥有 GWAS 和基因座鑑定方面的专业知识。各种纵向和功能基因组中心正在建设中，以研究由遗传性疾病引起的疾病型态，例如糖尿病、阿兹海默症。此外，基因组和转录组技术在该领域得到了更广泛的应用，包括人类细胞图谱。这些是影响基因组学和转录组市场占有率份额成长的关键因素。

学术领域的扩大使用预计将推动市场

空间基因组研究经常在学术研究机构中使用，以提供对多种疾病的深入研究。例如，费城儿童医院研究中心建立了空间和功能基因组学中心，利用基于 3D 基因组学的方法研究几种流行疾病的遗传基础。大学研究人员可以透过空间基因组学和转录组学来探索基因表现动态的新领域。这种方法对于分析遗传疾病的细胞型态状态的学术研究人员很有价值，并已应用于人类细胞图谱等研究计划。

转录组学的采用增加

与基因组学领域相比，越来越多地采用转录组学进行单细胞转录组学分析，进一步推动了太空基因组学和转录组学市场的扩张。雷射捕获晶粒切割技术（LCM）等自动化序列测定技术正在满足生物材料核酸序列测定的需求，推动空间基因组学业务的扩张。此外，对组织异质性的理解的加深催生了最先进的测序资料资料以后使用。预计这一方面将在预期期间推动空间基因组学和转录组学市场的成长。

预计北美将在空间基因组学和转录组学市场中占据很大份额

由于疾病病理学研究的策略性投资以及转录组学研究和开发的重要性日益增加，预计北美将出现强劲增长。例如，美国卫生研究院通用基金正在进行的单细胞分析计画的重点是使用定序方法和基于萤光的方法来提高空间分辨率。

随着许多综合医院和其他相关组织实施基于基因组学的疾病预防，市场预计将随着新技术的发展和产品的推出而扩大。例如，2022年3月，美国国立卫生研究院宣布已收集了来自不同物种的约10万个全基因组序列。

多家综合医院政府倡议的成长

多家综合医院和其他有兴趣的机构引入基因组疾病预防，以及新的进展和产品的发布，预计将推动该行业的成长。例如，Illumina 和 Genetic Alliance 于 2021 年 11 月推出了一项耗资 1.2 亿美元的全球宣传活动，旨在增加公平性并改善受遗传疾病影响的家庭的结果。此外，美国国立卫生研究院于 2022 年 3 月宣布，已从多个物种收集了约 10 万个全基因组序列。这表明北美政府机构高度重视基因组学，预计这将在预测期内推动空间基因组学和转录组学市场的成长。

手术规划软体产品

Visium 空间基因表现是一种下一代分子分析技术，可根据总 mRNA 对组织进行分类。此外，整个转录组将映射到 FFPE 或新鲜冷冻组织的型态背景上，以获得对健康发育、疾病病理学和临床转化研究的新见解。 GeoMx 数位空间分析器 对于空间转录组和空间蛋白质组研究，GeoMx 数位空间分析器 (DSP) 仅透过一张幻灯片即可提供型态背景。 GeoMx DSP 是适应性最强、最可靠的空间生物学系统，旨在满足从探索性研究到转化​​性研究不断变化的研究需求。

市场开拓的主要进展

2023 年 2 月，Curio Bioscience 宣布商业发布 Curio Seeker，这是一种使用高分辨率成像方法的全转录组空间作图套件。 2022年10月，Oxford Nanopore Technologies与10x Genomics共同开发了用于单细胞和空间全长异构体定序的耗材。 2022 年 6 月，在奥兰多举行的 AGBT 大会上，10x Genomics 宣布了包括 Chromium、Visium 和 Xenium 在内的新产品。

目录

第一章简介

  • 市场概况
  • 市场定义
  • 调查范围
  • 市场区隔
  • 货币
  • 先决条件
  • 基准年和预测年时间表

第二章调查方法

  • 调查资料
  • 先决条件

第三章执行摘要

  • 研究亮点

第四章市场动态

  • 市场驱动因素
  • 市场抑制因素
  • 波特五力分析
  • 产业价值链分析

第五章空间基因组学和转录组学市场：副产品

  • 介绍
  • 空间转录组学
    • 基于序列的方法
    • IHC
    • 基于显微镜的 RNA成像技术
  • 空间基因体学
    • FISH
    • 基于显微镜的活体 DNA 成像
    • 基因组扰动工具
    • 大规模平行序列
    • 生化方法
    • 其他的

第六章 空间基因体学与转录组学市场：依技术分类

  • 介绍
  • 装置
  • 消耗品
  • 软体

第七章 空间基因体学与转录组学市场：依最终用途

  • 介绍
  • 转化研究
  • 学术客户
  • 诊断客户
  • 药品製造商

第八章空间基因组学和转录组学市场：按地区

  • 介绍
  • 北美洲
    • 美国
    • 加拿大
    • 墨西哥
  • 南美洲
    • 巴西
    • 阿根廷
    • 其他的
  • 欧洲
    • 英国
    • 德国
    • 法国
    • 西班牙
    • 其他的
  • 中东/非洲
    • 沙乌地阿拉伯
    • 阿拉伯聯合大公国
    • 以色列
    • 其他的
  • 亚太地区
    • 日本
    • 中国
    • 印度
    • 韩国
    • 印尼
    • 泰国
    • 其他的

第九章竞争环境及分析

  • 主要企业及策略分析
  • 新兴企业和市场盈利
  • 合併、收购、协议和合作
  • 供应商竞争力矩阵

第十章 公司简介

  • Natera Inc.
  • 10x Genomics
  • Dovetail Genomics
  • Illumina, Inc.
  • S2 Genomics, Inc.
  • NanoString Technologies, Inc.
  • Seven Bridges Genomics
  • Horizon Discovery Group plc
  • Bio-Techne
简介目录
Product Code: KSI061615762

The spatial genomics and transcriptomics market is estimated to grow at a CAGR of 17.38% during the forecast period.

Spatial genomics and transcriptomics are referred to as the application of cutting-edge technologies that help with the analysis of gene expression patterns and visualizations. The market for spatial genomics and transcriptomics is expanding significantly due to the growing need for precision medicine and the progress made in single-cell analysis. These technologies have great potential in a number of sectors since they provide insights into the spatial organisation of genes and genetic material within tissues at the same time. They aid in the deciphering of the complexity of tumour microenvironments and heterogeneity in cancer research, directing the creation of focused treatments and diagnostics.

Growth drivers for the spatial genomics and transcriptomics market

Drug discovery and development is experiencing an increasing need for spatial genomics and transcriptomics markets. Drug discovery and development are seeing increasing applications for spatial genomics and transcriptomics. The focus of this demand has recently shifted from research to drug discovery and development, notably for diseases like cancer and neurological illnesses. The launch of the fourth generation of sequencing and the growing potential of spatial genomic analysis as a cancer diagnosis tool is expected to further fuel the spatial genomics and transcriptomics market.

Rising research in genomics and transcriptomics applications

Researchers from academic institutes are the major element influencing genomics and transcriptomics market growth. For instance, a research centre like Children's Hospital for Philadelphia has expertise in GWAS and locus identification in both academic and biotech environments. Various longitudinal and functional genomics centres have been built to investigate the morphology of diseases brought by genetic disorders, including diabetes, cancer, and Alzheimer's. Additionally, there are more extensive uses for genomic and transcriptomic technology in the field, including the Human Cell Atlas. These are the key factors influencing the growth of genomics and transcriptomics market share.

Growing use in the academic field is anticipated to drive the market

The spatial genomic studies are being used frequently in academic research facilities as they offer a thorough study of a wide range of illnesses. For instance, the Children's Hospital of Philadelphia's research centre has established a Centre of Spatial and Functional Genomics to investigate the genetic basis of several prevalent illnesses using 3D genomics-based methods. Researchers at universities can investigate novel regions of gene expression dynamics due to spatial genomics and transcriptomics. The approach is valuable for academic researchers who analyse the morphological status of cells for genetically derived disorders and find applications in research projects like the Human Cell Atlas.

Rising adoption of transcriptomics

The spatial genomics and transcriptomics market expansion is further fueled by the increased adoption of transcriptomics for single-cell transcriptomics analysis as compared to the genomics segment. The demand for nucleic acid sequencing of biological materials has been answered by automated sequencing techniques like the laser capture microdissection technique (LCM), which has propelled the expansion of the spatial genomics business. Additionally, a heightened understanding of tissue heterogeneity has sparked the creation of cutting-edge sequencing technology intended to archive genetic or spatial data for later use. It is predicted that during the anticipated period, this aspect will fuel spatial genomics and transcriptomics market growth.

North America is predicted to hold a significant market share in the spatial genomics and transcriptomics market

North America is anticipated to grow significantly due to the strategic investments in disease pathology research and the increasing importance of transcriptomics R&D. For instance, the ongoing Single Cell Analysis Programme of the National Institutes of Health Common Fund focuses on sequencing methodologies and improving spatial resolution using fluorescence-based approaches.

Numerous general hospitals and other concerned organisations' implementation of genomics-based illness prevention is anticipated to aid the market's expansion along with new technological developments and product introductions. For instance, in March 2022, the National Institutes of Health declared that it had a collection of around 100,000 whole-genome sequencing from diverse species.

Growth in government initiatives in several general hospitals

The introduction of preventative illness through genomics by several general hospitals and other concerned organisations is predicted to fuel the industry growth along with new advancements and product releases. For instance, Illumina and the Genetic Alliance established a USD 120 million worldwide campaign in November 2021 to boost fairness and improve outcomes for families impacted by genetic disorders. Furthermore, The National Institutes of Health also announced in March 2022 that it had a collection of approximately 100,000 whole-genome sequencing from a wide range of species. This suggests that North American government organisations place a high priority on genomics, which is anticipated to fuel the spatial genomics and transcriptomics market's growth throughout the projected period.

Surgical Planning Software Products

  • Visium Spatial Gene Expression, to categorise tissue based on total mRNA, Visium Spatial Gene Expression is a next-generation molecular profiling technology. In addition, to gain new insights into healthy development, disease pathology, and clinical translational research, the whole transcriptome with morphological context in FFPE or fresh frozen tissues is mapped.
  • GeoMx Digital Spatial Profiler, in spatial transcriptomics and spatial proteomics investigations, the GeoMx Digital Spatial Profiler (DSP) gives morphological context from only one slide. The GeoMx DSP is the most adaptable and reliable spatial biology system created to meet constantly changing research demands, from discovery to translational research.

Market Key Developments

  • In February 2023, The commercial release of Curio Seeker, a whole-transcriptome spatial mapping kit with a high-resolution imaging method, was announced by Curio Bioscience.
  • In October 2022, To produce consumables for single-cell and spatial full-length isoform transcript sequencing, Oxford Nanopore Technologies and 10x Genomics worked together.
  • In June 2022, At the AGBT general conference in Orlando, 10x Genomics introduced several new products, including Chromium, Visium, and Xenium.

Segmentation:

By Product

  • Spatial Transcriptomics
  • Sequencing-Based Methods
  • IHC
  • Microscopy-based RNA Imaging Techniques
  • Spatial Genomics
  • FISH
  • Microscopy-based Live DNA Imaging
  • Genome Perturbation Tools
  • Massively-Parallel Sequencing
  • Biochemical Techniques
  • Others

By Technology

  • Instruments
  • Consumables
  • Software

By End-User

  • Translational Research
  • Academic Customers
  • Diagnostic Customers
  • Pharmaceutical Manufacturer

By Geography

  • North America
  • United States
  • Canada
  • Mexico
  • South America
  • Brazil
  • Argentina
  • Others
  • Europe
  • United Kingdom
  • Germany
  • France
  • Spain
  • Others
  • Middle East and Africa
  • Saudi Arabia
  • UAE
  • Israel
  • Others
  • Asia Pacific
  • Japan
  • China
  • India
  • South Korea
  • Indonesia
  • Thailand
  • Others

TABLE OF CONTENTS

1. INTRODUCTION

  • 1.1. Market Overview
  • 1.2. Market Definition
  • 1.3. Scope of the Study
  • 1.4. Market Segmentation
  • 1.5. Currency
  • 1.6. Assumptions
  • 1.7. Base, and Forecast Years Timeline

2. RESEARCH METHODOLOGY

  • 2.1. Research Data
  • 2.2. Assumptions

3. EXECUTIVE SUMMARY

  • 3.1. Research Highlights

4. MARKET DYNAMICS

  • 4.1. Market Drivers
  • 4.2. Market Restraints
  • 4.3. Porter's Five Force Analysis
    • 4.3.1. Bargaining Power of Suppliers
    • 4.3.2. Bargaining Power of Buyers
    • 4.3.3. Threat of New Entrants
    • 4.3.4. Threat of Substitutes
    • 4.3.5. Competitive Rivalry in the Industry
  • 4.4. Industry Value Chain Analysis

5. SPATIAL GENOMICS AND TRANSCRIPTOMICS MARKET, BY PRODUCT

  • 5.1. Introduction
  • 5.2. Spatial Transcriptomics
    • 5.2.1. Sequencing-Based Methods
    • 5.2.2. IHC
    • 5.2.3. Microscopy-based RNA Imaging Techniques
  • 5.3. Spatial Genomics
    • 5.3.1. FISH
    • 5.3.2. Microscopy-based Live DNA Imaging
    • 5.3.3. Genome Perturbation Tools
    • 5.3.4. Massively-Parallel Sequencing
    • 5.3.5. Biochemical Techniques
    • 5.3.6. Others

6. SPATIAL GENOMICS AND TRANSCRIPTOMICS MARKET, BY TECHNOLOGY

  • 6.1. Introduction
  • 6.2. Instruments
  • 6.3. Consumables
  • 6.4. Software

7. SPATIAL GENOMICS AND TRANSCRIPTOMICS MARKET, BY END-USE

  • 7.1. Introduction
  • 7.2. Translational Research
  • 7.3. Academic Customers
  • 7.4. Diagnostic Customers
  • 7.5. Pharmaceutical Manufacturer

8. SPATIAL GENOMICS AND TRANSCRIPTOMICS MARKET, BY GEOGRAPHY

  • 8.1. Introduction
  • 8.2. North America
    • 8.2.1. United States
    • 8.2.2. Canada
    • 8.2.3. Mexico
  • 8.3. South America
    • 8.3.1. Brazil
    • 8.3.2. Argentina
    • 8.3.3. Others
  • 8.4. Europe
    • 8.4.1. United Kingdom
    • 8.4.2. Germany
    • 8.4.3. France
    • 8.4.4. Spain
    • 8.4.5. Others
  • 8.5. The Middle East and Africa
    • 8.5.1. Saudi Arabia
    • 8.5.2. UAE
    • 8.5.3. Israel
    • 8.5.4. Others
  • 8.6. Asia Pacific
    • 8.6.1. Japan
    • 8.6.2. China
    • 8.6.3. India
    • 8.6.4. South Korea
    • 8.6.5. Indonesia
    • 8.6.6. Thailand
    • 8.6.7. Others

9. COMPETITIVE ENVIRONMENT AND ANALYSIS

  • 9.1. Major Players and Strategy Analysis
  • 9.2. Emerging Players and Market Lucrativeness
  • 9.3. Mergers, Acquisitions, Agreements, and Collaborations
  • 9.4. Vendor Competitiveness Matrix

10. COMPANY PROFILES

  • 10.1. Natera Inc.
  • 10.2. 10x Genomics
  • 10.3. Dovetail Genomics
  • 10.4. Illumina, Inc.
  • 10.5. S2 Genomics, Inc.
  • 10.6. NanoString Technologies, Inc.
  • 10.7. Seven Bridges Genomics
  • 10.8. Horizon Discovery Group plc
  • 10.9. Bio-Techne