首页 > 市场调查报告书 > 製药

生物製剂

市场调查报告书

商品编码

1627538

分子交换器市场:治疗标的，医药品开发，药物输送机制，各适应症用途:2025年

Molecular Switches As Therapeutic Targets, Drug Development, Drug Delivery Mechanism & Application By Indications Insight 2025

出版日期: 2025年01月01日 | 出版商:

KuicK Research | 英文 150 Pages | 商品交期: 最快1-2个工作天内

价格

简介目录图表

分子开关是动态实体，可以回应特定的环境或生物触发因素在不同状态之间转换。这些触发因素包括 pH 值、光照射、温度、氧化还原条件以及某些离子和生物分子的存在的变化。分子开关的概念为高度控制的诊断和治疗系统提供了基础，对医疗和製药领域产生了重大影响。精确控制生物反应的能力使得分子开关对于先进药物输送系统、即时诊断工具和个人化治疗介入的开发至关重要。

在製药领域，分子开关透过精确时空控制活性药物成分的释放，彻底改变了药物传递。 pH敏感分子开关已用于基于奈米颗粒的药物载体，其在正常生理条件下保持稳定，但在酸性环境中降解以释放有效负载。例如，FPBC@SN 奈米颗粒系统整合了一个针对乳癌细胞酸性细胞质的 pH 敏感分子开关。此系统释放索拉非尼（诱导铁死亡）和 IDO 抑制剂（增强肿瘤免疫力）。透过利用此类开关，这些系统可以减少脱靶效应，提高治疗指数，并解决肿瘤学中的重要课题。

本报告提供全球分子交换器市场相关调查，市场概要，以及分子交换器治疗目标的重要性，各市场区隔趋势，新兴技术与今后预测等资讯。

Molecular Switches In Cancer Therapeutics: Breast Cancer, Prostate Cancer, Lung Cancer, Colorectal Cancer, Gastric Cancer
Molecular Switches In Neurological Disorder: Parkinson's Disease, Alzheimer's Disease, Multiple Sclerosis
Molecular Switches In Autoimmune & Inflammatory Disorder: Diabetes, Arthritis, Lupus, Psoriasis

Molecular switches are dynamic entities capable of transitioning between distinct states in response to specific environmental or biological triggers. These triggers can include changes in pH, light exposure, temperature, redox conditions, or the presence of certain ions or biomolecules. The concept of molecular switching has significantly influenced the medical and pharmaceutical domain by providing a foundation for highly controlled diagnostic and therapeutic systems. The ability to precisely regulate biological responses has made molecular switches indispensable in the development of advanced drug delivery systems, real-time diagnostic tools, and personalized therapeutic interventions.

In the pharmaceutical sector, molecular switches have revolutionized drug delivery by enabling precise spatiotemporal control over the release of active pharmaceutical ingredients. One of the most widely explored triggers is pH, as pathological conditions like cancer and inflammation often create acidic microenvironments. pH-sensitive molecular switches are employed in nanoparticle-based drug carriers, which remain stable under normal physiological conditions but disassemble in acidic environments to release their payload. For example, the FPBC@SN nanoparticle system integrates a pH-sensitive molecular switch to target acidic cytoplasm in breast cancer cells. This system releases both sorafenib, which induces ferroptosis, and an IDO inhibitor to enhance tumor immunity. By leveraging such switches, these systems reduce off-target effects and enhance the therapeutic index, addressing key challenges in oncology.

1. Introduction To Molecular Switches

1.1 Overview
1.2 History & Emergence In Medicine

2. Molecular Switches Clinical Significance In Medicine

3. Molecular Switches Significance In Drug Delivery & Release

3.1 Overview
3.2 Ongoing Research & Developments

4. Molecular Switches Significance As Therapeutic Targets

5. Molecular Switches - Broad Classification

6. Molecular Switches By Cancer Indication

6.1 Breast Cancer
6.2 Prostate Cancer
6.3 Colorectal cancer
6.4 Lung Cancer
6.5 Gastric Cancer

7. Molecular Switches By Neurological Disorder

7.1 Parkinson's Disease
7.2 Alzheimer's Disease
7.3 Multiple Sclerosis

8. Molecular Switches By Infectious Disease

8.1 Viral Infection
8.2 Bacterial Infection

9. Molecular Switches By Autoimmune & Inflammatory Disorder

9.1 Diabetes
9.2 Arthritis
9.3 Lupus
9.4 Psoriasis

10. Molecular Switches By Cardiovascular Disease

10.1 Myocardial Infarction (Heart Attack)
10.2 Others

11. Molecular Switches Significance In Regenerative Medicine

12. Sales Insight Of Key Drugs Targeting Molecular Switches

13. Molecular Switches In Drug Formulation

13.1 Smart Drug Formulations & Molecular Switches
13.2 Biomaterial Based Drug Delivery Systems
13.3 Self Regulating Drug Systems

14. Current Trends & Emerging Technologies

14.1 Molecular Switches In Nanomedicine
14.2 Innovations In Responsive Drug Systems
14.3 Integration With Artificial Intelligence & Machine Learning

15. Future Perspectives & Directions

15.1 Advancements In Molecular Switch Technology
15.2 The Future Of Personalized Medicine With Molecular Switches
15.3 Potential Impact On Drug Discovery & Therapeutics

简介目录图表

List of Figures

Figure 1-1: Molecular Switches - Introduction
Figure 1-2: Molecular Switches - Emergence & Evolution
Figure 3-1: Molecular Switches In Drug Delivery & Release
Figure 3-2: Drug Delivery Systems With Molecular Switches
Figure 3-3: Peptide-Based Drug Delivery System
Figure 3-4: Switchable Molecular Tweezers
Figure 3-5: Rotaxane-Based Drug Delivery System
Figure 3-6: Enzyme-Activatable Drug Delivery System
Figure 3-7: Light-Responsive Drug Delivery Systems
Figure 3-8: Photo-Responsive Drug Delivery Using Spiropyran
Figure 3-9: Photopharmacological Approach For Neuropathic Pain
Figure 3-10: Insulin Prodrug Activation
Figure 6-1: AR Activation & Its Dual Role In Tumor Growth
Figure 6-2: PRL-3 Activation & AMPI-109's Impact On TNBC
Figure 6-3: Molecular Switch in Prostate Cancer
Figure 7-1: PINK1-Parkin Molecular Switch In Parkinson's Disease
Figure 8-1: Molecular Switches In Viral infections

Figure 11 1: Molecular Switches In Regenerative Medicine

Figure 13-1: Smart Drug Delivery With Molecular Switches
Figure 13-2: Biomaterial Based Drug Delivery Systems With Molecular Switches
Figure 13-3: Self-regulating Drug Systems With Molecular Switches
Figure 14-1: Molecular Switches In Nanomedicine
Figure 14-2: Molecular switches In Responsive Drug Systems
Figure 14-3: Integration Of Molecular Switches With Artificial Intelligence & Machine Learning

List of Tables

Table 1-1: Traditional v/s Molecular Switch Enabled Drug Delivery
Table 4-1: Examples Of Approved Drugs Targeting Molecular Switches
Table 5-1: Molecular Switches - Broad Classification
Table 12-1: Top 20 Drugs Targeting Molecular Switches (US$ Billion), 2022-2024

02-2729-4219

+886-2-2729-4219

License/价格

分子交换器市场:治疗标的，医药品开发，药物输送机制，各适应症用途:2025年

Molecular Switches As Therapeutic Targets, Drug Development, Drug Delivery Mechanism & Application By Indications Insight 2025

目录

第1章分子交换器的简介

第2章分子交换器的医学的意义

第3章药物输送和放出的分子交换器的重要性

第4章分子交换器治疗目标的重要性

第5章分子交换器- 大分类

第6章分子交换器，癌症各适应症

第7章分子交换器，神经各疾病

第8章分子交换器，感染疾病

第9章分子交换器，自体免疫疾病和发炎性各疾病

第10章分子交换器，各心血管疾病

第11章再生医疗的分子交换器的重要性

第12章把分子交换器作为标的主要医药品的销售趋势

第13章医药品处方的分子交换器

第14章目前趋势与新兴技术

第15章未来展望与方向性